-
1
-
-
0028062665
-
History of drugs for thrombotic disease. Discovery, development, and directions for the future
-
Mueller R.L., Scheidt S. History of drugs for thrombotic disease. Discovery, development, and directions for the future. Circulation. 89:1994;432-449.
-
(1994)
Circulation
, vol.89
, pp. 432-449
-
-
Mueller, R.L.1
Scheidt, S.2
-
2
-
-
0014783280
-
Teratogenic compounds of Veratrum californicum (Durand) X. Cyclopia in rabbits produced by cyclopamine
-
Keeler R.F. Teratogenic compounds of Veratrum californicum (Durand) X. Cyclopia in rabbits produced by cyclopamine. Teratology. 3:1970;175-180.
-
(1970)
Teratology
, vol.3
, pp. 175-180
-
-
Keeler, R.F.1
-
4
-
-
0029920318
-
Paul Ehrlich: Pathfinder in cell biology. 1. Chronicle of his life and accomplishments in immunology, cancer research, and chemotherapy
-
Kasten F.H. Paul Ehrlich. pathfinder in cell biology. 1. Chronicle of his life and accomplishments in immunology, cancer research, and chemotherapy Biotech. Histochem. 71:1996;2-37.
-
(1996)
Biotech. Histochem.
, vol.71
, pp. 2-37
-
-
Kasten, F.H.1
-
5
-
-
85030967529
-
Prescriptions and polio
-
J. Ryan, A. Newman, and J.M., eds. ACS Publications
-
Tweedy, B.D., and Lesney, M.S. (2000). Prescriptions and polio. In The Pharmaceutical Century: Ten Decades of Drug Discovery, J. Ryan, A. Newman, and J.M., eds. ACS Publications http://pubs.acs.org/journals/pharmcent/index.html .
-
(2000)
The Pharmaceutical Century: Ten Decades of Drug Discovery
-
-
Tweedy, B.D.1
Lesney, M.S.2
-
6
-
-
0037416141
-
The small molecule approach to biology
-
Schreiber S.L. The small molecule approach to biology. Chem. Eng. News. 81:2003;51-61.
-
(2003)
Chem. Eng. News
, vol.81
, pp. 51-61
-
-
Schreiber, S.L.1
-
7
-
-
0035657098
-
The art and design of genetic screens: Zebrafish
-
Patton E.E., Zon L.I. The art and design of genetic screens. zebrafish Nat. Rev. Genet. 2:2001;956-966.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 956-966
-
-
Patton, E.E.1
Zon, L.I.2
-
8
-
-
0036731971
-
Headwaters of the zebrafish-emergence of a new model vertebrate
-
Grunwald D.J., Eisen J.S. Headwaters of the zebrafish-emergence of a new model vertebrate. Nat. Rev. Genet. 3:2002;717-724.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 717-724
-
-
Grunwald, D.J.1
Eisen, J.S.2
-
9
-
-
0035834358
-
Genomics. Zebrafish-the canonical vertebrate
-
Fishman M.C. Genomics. Zebrafish-the canonical vertebrate. Science. 294:2001;1290-1291.
-
(2001)
Science
, vol.294
, pp. 1290-1291
-
-
Fishman, M.C.1
-
10
-
-
0037370495
-
The transformation of the model organism: A decade of developmental genetics
-
Anderson K.V., Ingham P.W. The transformation of the model organism. a decade of developmental genetics Nat. Genet. 33:2003;285-293.
-
(2003)
Nat. Genet.
, vol.33
, pp. 285-293
-
-
Anderson, K.V.1
Ingham, P.W.2
-
11
-
-
0042673755
-
Anterior and posterior waves of cyclic her1 gene expression are differentially regulated in the presomitic mesoderm of zebrafish
-
Gajewski M., Sieger D., Alt B., Leve C., Hans S., Wolff C., Rohr K.B., Tautz D. Anterior and posterior waves of cyclic her1 gene expression are differentially regulated in the presomitic mesoderm of zebrafish. Development. 130:2003;4269-4278.
-
(2003)
Development
, vol.130
, pp. 4269-4278
-
-
Gajewski, M.1
Sieger, D.2
Alt, B.3
Leve, C.4
Hans, S.5
Wolff, C.6
Rohr, K.B.7
Tautz, D.8
-
12
-
-
0038636259
-
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish
-
Liu N.A., Huang H., Yang Z., Herzog W., Hammerschmidt M., Lin S., Melmed S. Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Mol. Endocrinol. 17:2003;959-966.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 959-966
-
-
Liu, N.A.1
Huang, H.2
Yang, Z.3
Herzog, W.4
Hammerschmidt, M.5
Lin, S.6
Melmed, S.7
-
14
-
-
0034802481
-
Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio)
-
Mattingly C.J., McLachlan J.A., Toscano W.A. Jr. Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio). Environ. Health Perspect. 109:2001;845-849.
-
(2001)
Environ. Health Perspect.
, vol.109
, pp. 845-849
-
-
Mattingly, C.J.1
McLachlan, J.A.2
Toscano W.A., Jr.3
-
15
-
-
0035907008
-
Genetic analysis of digestive physiology using fluorescent phospholipid reporters
-
Farber S.A., Pack M., Ho S.Y., Johnson I.D., Wagner D.S., Dosch R., Mullins M.C., Hendrickson H.S., Hendrickson E.K., Halpern M.E. Genetic analysis of digestive physiology using fluorescent phospholipid reporters. Science. 292:2001;1385-1388.
-
(2001)
Science
, vol.292
, pp. 1385-1388
-
-
Farber, S.A.1
Pack, M.2
Ho, S.Y.3
Johnson, I.D.4
Wagner, D.S.5
Dosch, R.6
Mullins, M.C.7
Hendrickson, H.S.8
Hendrickson, E.K.9
Halpern, M.E.10
-
16
-
-
0036389722
-
Construction of a zebrafish cDNA microarray: Gene expression profiling of the zebrafish during development
-
Ton C., Stamatiou D., Dzau V.J., Liew C.C. Construction of a zebrafish cDNA microarray. gene expression profiling of the zebrafish during development Biochem. Biophys. Res. Commun. 296:2002;1134-1142.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
, pp. 1134-1142
-
-
Ton, C.1
Stamatiou, D.2
Dzau, V.J.3
Liew, C.C.4
-
17
-
-
0036917021
-
Rapid mapping of zebrafish mutations with SNPs and oligonucleotide microarrays
-
Stickney H.L., Schmutz J., Woods I.G., Holtzer C.C., Dickson M.C., Kelly P.D., Myers R.M., Talbot W.S. Rapid mapping of zebrafish mutations with SNPs and oligonucleotide microarrays. Genome Res. 12:2002;1929-1934.
-
(2002)
Genome Res.
, vol.12
, pp. 1929-1934
-
-
Stickney, H.L.1
Schmutz, J.2
Woods, I.G.3
Holtzer, C.C.4
Dickson, M.C.5
Kelly, P.D.6
Myers, R.M.7
Talbot, W.S.8
-
18
-
-
0036022515
-
Cloned zebrafish by nuclear transfer from long-term-cultured cells
-
Lee K.Y., Huang H., Ju B., Yang Z., Lin S. Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat. Biotechnol. 20:2002;795-799.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 795-799
-
-
Lee, K.Y.1
Huang, H.2
Ju, B.3
Yang, Z.4
Lin, S.5
-
19
-
-
0033780376
-
Effective targeted gene 'knockdown' in zebrafish
-
Nasevicius A., Ekker S.C. Effective targeted gene 'knockdown' in zebrafish. Nat. Genet. 26:2000;216-220.
-
(2000)
Nat. Genet.
, vol.26
, pp. 216-220
-
-
Nasevicius, A.1
Ekker, S.C.2
-
21
-
-
12644303221
-
The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio
-
Haffter P., Granato M., Brand M., Mullins M.C., Hammerschmidt M., Kane D.A., Odenthal J., van Eeden F.J., Jiang Y.J., Heisenberg C.P.et al. The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development. 123:1996;1-36.
-
(1996)
Development
, vol.123
, pp. 1-36
-
-
Haffter, P.1
Granato, M.2
Brand, M.3
Mullins, M.C.4
Hammerschmidt, M.5
Kane, D.A.6
Odenthal, J.7
Van Eeden, F.J.8
Jiang, Y.J.9
Heisenberg, C.P.10
-
22
-
-
12644268233
-
A genetic screen for mutations affecting embryogenesis in zebrafish
-
Driever W., Solnica-Krezel L., Schier A.F., Neuhauss S.C., Malicki J., Stemple D.L., Stainier D.Y., Zwartkruis F., Abdelilah S., Rangini Z.et al. A genetic screen for mutations affecting embryogenesis in zebrafish. Development. 123:1996;37-46.
-
(1996)
Development
, vol.123
, pp. 37-46
-
-
Driever, W.1
Solnica-Krezel, L.2
Schier, A.F.3
Neuhauss, S.C.4
Malicki, J.5
Stemple, D.L.6
Stainier, D.Y.7
Zwartkruis, F.8
Abdelilah, S.9
Rangini, Z.10
-
23
-
-
0034700166
-
Small molecule developmental screens reveal the logic and timing of vertebrate development
-
Peterson R.T., Link B.A., Dowling J.E., Schreiber S.L. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc. Natl. Acad. Sci. USA. 97:2000;12965-12969.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12965-12969
-
-
Peterson, R.T.1
Link, B.A.2
Dowling, J.E.3
Schreiber, S.L.4
-
24
-
-
0002452569
-
Developmental roles and clinical significance of hedgehog signaling
-
McMahon A.P., Ingham P.W., Tabin C.J. Developmental roles and clinical significance of hedgehog signaling. Curr. Top. Dev. Biol. 53:2003;1-114.
-
(2003)
Curr. Top. Dev. Biol.
, vol.53
, pp. 1-114
-
-
McMahon, A.P.1
Ingham, P.W.2
Tabin, C.J.3
-
25
-
-
0036829397
-
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
-
Chen J.K., Taipale J., Cooper M.K., Beachy P.A. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev. 16:2002;2743-2748.
-
(2002)
Genes Dev.
, vol.16
, pp. 2743-2748
-
-
Chen, J.K.1
Taipale, J.2
Cooper, M.K.3
Beachy, P.A.4
-
26
-
-
0038376480
-
Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo
-
Wolff C., Roy S., Ingham P.W. Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Curr. Biol. 13:2003;1169-1181.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1169-1181
-
-
Wolff, C.1
Roy, S.2
Ingham, P.W.3
-
27
-
-
0035797939
-
Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul
-
Peterson R.T., Mably J.D., Chen J.N., Fishman M.C. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Curr. Biol. 11:2001;1481-1491.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1481-1491
-
-
Peterson, R.T.1
Mably, J.D.2
Chen, J.N.3
Fishman, M.C.4
-
28
-
-
0033485896
-
Chemistry or biology: Which comes first after the genome is sequenced?
-
King R.W. Chemistry or biology. which comes first after the genome is sequenced? Chem. Biol. 6:1999;R327-R333.
-
(1999)
Chem. Biol.
, vol.6
-
-
King, R.W.1
-
29
-
-
0141732260
-
Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening
-
Khersonsky S.M., Jung D.-W., Kang T.-W., Walsh D.P., Moon H.S., Jo H., Jacobson E.M., Shetty V., Neubert T.A., Chang Y.T. Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening. J. Am. Chem. Soc. 125:2003;11804-11805.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 11804-11805
-
-
Khersonsky, S.M.1
Jung, D.-W.2
Kang, T.-W.3
Walsh, D.P.4
Moon, H.S.5
Jo, H.6
Jacobson, E.M.7
Shetty, V.8
Neubert, T.A.9
Chang, Y.T.10
-
32
-
-
0037347582
-
Zebrafish: From disease modeling to drug discovery
-
Rubinstein A.L. Zebrafish. from disease modeling to drug discovery Curr. Opin. Drug Discov. Dev. 6:2003;218-223.
-
(2003)
Curr. Opin. Drug Discov. Dev.
, vol.6
, pp. 218-223
-
-
Rubinstein, A.L.1
-
33
-
-
0036340364
-
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels
-
Roman B.L., Pham V.N., Lawson N.D., Kulik M., Childs S., Lekven A.C., Garrity D.M., Moon R.T., Fishman M.C., Lechleider R.J.et al. Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels. Development. 129:2002;3009-3019.
-
(2002)
Development
, vol.129
, pp. 3009-3019
-
-
Roman, B.L.1
Pham, V.N.2
Lawson, N.D.3
Kulik, M.4
Childs, S.5
Lekven, A.C.6
Garrity, D.M.7
Moon, R.T.8
Fishman, M.C.9
Lechleider, R.J.10
-
34
-
-
0028803128
-
Gridlock, a localized heritable vascular patterning defect in the zebrafish
-
Weinstein B.M., Stemple D.L., Driever W., Fishman M.C. Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nat. Med. 1:1995;1143-1147.
-
(1995)
Nat. Med.
, vol.1
, pp. 1143-1147
-
-
Weinstein, B.M.1
Stemple, D.L.2
Driever, W.3
Fishman, M.C.4
-
35
-
-
18744363879
-
Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos
-
Davis J.M., Clay H., Lewis J.L., Ghori N., Herbomel P., Ramakrishnan L. Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. Immunity. 17:2002;693-702.
-
(2002)
Immunity
, vol.17
, pp. 693-702
-
-
Davis, J.M.1
Clay, H.2
Lewis, J.L.3
Ghori, N.4
Herbomel, P.5
Ramakrishnan, L.6
-
36
-
-
0042829260
-
Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections
-
Van Der Sar A.M., Musters R.J., Van Eeden F.J., Appelmelk B.J., Vandenbroucke-Grauls C.M., Bitter W. Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections. Cell. Microbiol. 5:2003;601-611.
-
(2003)
Cell. Microbiol.
, vol.5
, pp. 601-611
-
-
Van Der Sar, A.M.1
Musters, R.J.2
Van Eeden, F.J.3
Appelmelk, B.J.4
Vandenbroucke-Grauls, C.M.5
Bitter, W.6
-
37
-
-
0037453021
-
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish
-
Milan D.J., Peterson T.A., Ruskin J.N., Peterson R.T., MacRae C.A. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation. 107:2003;1355-1358.
-
(2003)
Circulation
, vol.107
, pp. 1355-1358
-
-
Milan, D.J.1
Peterson, T.A.2
Ruskin, J.N.3
Peterson, R.T.4
MacRae, C.A.5
-
38
-
-
0041817808
-
Zebrafish: A new model on the pharmaceutical catwalk
-
Langheinrich U. Zebrafish. a new model on the pharmaceutical catwalk Bioessays. 25:2003;904-912.
-
(2003)
Bioessays
, vol.25
, pp. 904-912
-
-
Langheinrich, U.1
-
39
-
-
0037138650
-
Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform
-
Spring D.R., Krishnan S., Blackwell H.E., Schreiber S.L. Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform. J. Am. Chem. Soc. 124:2002;1354-1363.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 1354-1363
-
-
Spring, D.R.1
Krishnan, S.2
Blackwell, H.E.3
Schreiber, S.L.4
-
40
-
-
0035961490
-
Split-pool synthesis of 1,3-dioxanes leading to arrayed stock solutions of single compounds sufficient for multiple phenotypic and protein-binding assays
-
Sternson S.M., Louca J.B., Wong J.C., Schreiber S.L. Split-pool synthesis of 1,3-dioxanes leading to arrayed stock solutions of single compounds sufficient for multiple phenotypic and protein-binding assays. J. Am. Chem. Soc. 123:2001;1740-1747.
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 1740-1747
-
-
Sternson, S.M.1
Louca, J.B.2
Wong, J.C.3
Schreiber, S.L.4
-
41
-
-
0037009971
-
A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening
-
Moon H.S., Jacobson E.M., Khersonsky S.M., Luzung M.R., Walsh D.P., Xiong W., Lee J.W., Parikh P.B., Lam J.C., Kang T.W.et al. A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. J. Am. Chem. Soc. 124:2002;11608-11609.
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 11608-11609
-
-
Moon, H.S.1
Jacobson, E.M.2
Khersonsky, S.M.3
Luzung, M.R.4
Walsh, D.P.5
Xiong, W.6
Lee, J.W.7
Parikh, P.B.8
Lam, J.C.9
Kang, T.W.10
-
42
-
-
0037255348
-
Issues related to the use of fish models in toxicologic pathology: Session introduction
-
Law J.M. Issues related to the use of fish models in toxicologic pathology. session introduction Toxicol. Pathol. 3:2003;49-52.
-
(2003)
Toxicol. Pathol.
, vol.3
, pp. 49-52
-
-
Law, J.M.1
|