A defect in novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish

Development

Volumn 129, Issue 24, 2002, Pages 5839-5846

  Liu, Shanming ^a   Lu, Weining ^a   Obara, Tomoko ^b   Kuida, Shiei ^a   Lehoczky, Jennifer ^c   Dewar, Ken ^c   Drummond, Iain A ^b   Beier, David R ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Renal Unit   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Mouse models; Nek kinase; PKD; Zebrafish

Indexed keywords

ACTIN; ANTISENSE OLIGONUCLEOTIDE; PROTEIN KINASE; PROTEIN NEK8; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOSKELETON; EMBRYO; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; GENETIC CONSERVATION; IN VITRO STUDY; KIDNEY POLYCYSTIC DISEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FAMILY; SPECIES; ZEBRA FISH;

AMINO ACID SEQUENCE; ANIMALS; CELL NUCLEUS; CLONING, MOLECULAR; COS CELLS; DATABASES; DISEASE MODELS, ANIMAL; GENOME; KIDNEY DISEASES, CYSTIC; MICE; MICE, INBRED C57BL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES, ANTISENSE; PHYSICAL CHROMOSOME MAPPING; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

ANIMALIA; DANIO RERIO; MURINAE;

EID: 0036931712     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00173     Document Type: Article

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