메뉴 건너뛰기




Volumn 13, Issue 5, 2003, Pages 270-277

Chemical genetics: Tailoring tools for cell biology

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPURVALANOL; FUMAGILLIN; ILIMAQUINONE; LACTACYSTIN; PURVALANOL; QUINONE DERIVATIVE; RAPAMYCIN; UNCLASSIFIED DRUG;

EID: 0038400185     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0962-8924(03)00077-1     Document Type: Review
Times cited : (88)

References (66)
  • 1
    • 0026343121 scopus 로고
    • Twenty-five years of cell cycle genetics
    • Hartwell L.H. Twenty-five years of cell cycle genetics. Genetics. 129:1991;975-980.
    • (1991) Genetics , vol.129 , pp. 975-980
    • Hartwell, L.H.1
  • 2
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S. The genetics of Caenorhabditis elegans. Genetics. 77:1974;71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 3
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nusslein-Volhard C., Wieschaus E. Mutations affecting segment number and polarity in Drosophila. Nature. 287:1980;795-801.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nusslein-Volhard, C.1    Wieschaus, E.2
  • 4
    • 0033874150 scopus 로고    scopus 로고
    • Unnatural ligands for engineered proteins: New tools for chemical genetics
    • Bishop A., et al. Unnatural ligands for engineered proteins: new tools for chemical genetics. Annu. Rev. Biophys. Biomol. Struct. 29:2000;577-606.
    • (2000) Annu. Rev. Biophys. Biomol. Struct. , vol.29 , pp. 577-606
    • Bishop, A.1
  • 5
    • 0026561901 scopus 로고
    • Brefeldin A: Insights into the control of membrane traffic and organelle structure
    • Klausner R.D., et al. Brefeldin A: insights into the control of membrane traffic and organelle structure. J. Cell Biol. 116:1992;1071-1080.
    • (1992) J. Cell Biol. , vol.116 , pp. 1071-1080
    • Klausner, R.D.1
  • 6
    • 0014107077 scopus 로고
    • The effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of Chinese hamster cells in vitro
    • Brinkley B.R., et al. The effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of Chinese hamster cells in vitro. J. Ultrastruct. Res. 19:1967;1-18.
    • (1967) J. Ultrastruct. Res. , vol.19 , pp. 1-18
    • Brinkley, B.R.1
  • 7
    • 0014117442 scopus 로고
    • The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein
    • Borisy G.G., Taylor E.W. The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein. J. Cell Biol. 34:1967;525-533.
    • (1967) J. Cell Biol. , vol.34 , pp. 525-533
    • Borisy, G.G.1    Taylor, E.W.2
  • 8
    • 0026569828 scopus 로고
    • Microtubule functions
    • Avila J. Microtubule functions. Life Sci. 50:1992;327-334.
    • (1992) Life Sci. , vol.50 , pp. 327-334
    • Avila, J.1
  • 9
    • 0034105412 scopus 로고    scopus 로고
    • Taxol in the management of cancers of the breast and the ovary
    • Khayat D., et al. Taxol in the management of cancers of the breast and the ovary. Cancer Invest. 18:2000;242-260.
    • (2000) Cancer Invest. , vol.18 , pp. 242-260
    • Khayat, D.1
  • 10
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Schiff P.B., et al. Promotion of microtubule assembly in vitro by taxol. Nature. 277:1979;665-667.
    • (1979) Nature , vol.277 , pp. 665-667
    • Schiff, P.B.1
  • 11
    • 0000297058 scopus 로고
    • Taxol stabilizes microtubules in mouse fibroblast cells
    • Schiff P.B., Horwitz S.B. Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl. Acad. Sci. U. S. A. 77:1980;1561-1565.
    • (1980) Proc. Natl. Acad. Sci. U. S. A. , vol.77 , pp. 1561-1565
    • Schiff, P.B.1    Horwitz, S.B.2
  • 12
    • 0020031810 scopus 로고
    • A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs)
    • Vallee R.B. A taxol-dependent procedure for the isolation of microtubules and microtubule-associated proteins (MAPs). J. Cell Biol. 92:1982;435-442.
    • (1982) J. Cell Biol. , vol.92 , pp. 435-442
    • Vallee, R.B.1
  • 13
    • 0027715517 scopus 로고
    • Analyzing microtubule motors in real time
    • Cohn S.A., et al. Analyzing microtubule motors in real time. Methods Cell Biol. 39:1993;75-88.
    • (1993) Methods Cell Biol. , vol.39 , pp. 75-88
    • Cohn, S.A.1
  • 14
    • 0000669419 scopus 로고    scopus 로고
    • Comprehensive survey of combinatorial library synthesis: 2001
    • Dolle R.E. Comprehensive survey of combinatorial library synthesis: 2001. J. Comb. Chem. 4:2002;369-418.
    • (2002) J. Comb. Chem. , vol.4 , pp. 369-418
    • Dolle, R.E.1
  • 15
    • 85031191844 scopus 로고    scopus 로고
    • On the World Wide Web URL: http://www.combichem.net .
  • 16
    • 0037012724 scopus 로고    scopus 로고
    • Pharmacophore features of potential drugs
    • Muegge I. Pharmacophore features of potential drugs. Chemistry. 8:2002;1976-1981.
    • (2002) Chemistry , vol.8 , pp. 1976-1981
    • Muegge, I.1
  • 17
    • 85031180061 scopus 로고    scopus 로고
    • http://www.ninds.nih.gov/funding/neurodegeneration/ NINDS_Drug_Screening.htm, http://www.hki-jena.de/hki_hp.htm
    • On the World Wide Web URL: http://dtp.nci.nih.gov/webdata.html, http://www.ninds.nih.gov/funding/neurodegeneration/NINDS_Drug_Screening.htm, http://www.hki-jena.de/hki_hp.htm .
  • 18
    • 0033863669 scopus 로고    scopus 로고
    • High-throughput screening: New technology for the 21st century
    • Hertzberg R.P., Pope A.J. High-throughput screening: new technology for the 21st century. Curr. Opin. Chem. Biol. 4:2000;445-451.
    • (2000) Curr. Opin. Chem. Biol. , vol.4 , pp. 445-451
    • Hertzberg, R.P.1    Pope, A.J.2
  • 19
    • 0033080348 scopus 로고    scopus 로고
    • High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications
    • Stockwell B.R., et al. High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications. Chem. Biol. 6:1999;71-83.
    • (1999) Chem. Biol. , vol.6 , pp. 71-83
    • Stockwell, B.R.1
  • 20
    • 0032212323 scopus 로고    scopus 로고
    • Automated recognition of patterns characteristic of subcellular structures in fluorescence microscopy images
    • Boland M.V., et al. Automated recognition of patterns characteristic of subcellular structures in fluorescence microscopy images. Cytometry. 33:1998;366-375.
    • (1998) Cytometry , vol.33 , pp. 366-375
    • Boland, M.V.1
  • 21
    • 0034700166 scopus 로고    scopus 로고
    • Small molecule developmental screens reveal the logic and timing of vertebrate development
    • Peterson R.T., et al. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc. Natl. Acad. Sci. U. S. A. 97:2000;12965-12969.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 12965-12969
    • Peterson, R.T.1
  • 22
    • 0034016816 scopus 로고    scopus 로고
    • Myoseverin, a microtubule-binding molecule with novel cellular effects
    • Rosania G.R., et al. Myoseverin, a microtubule-binding molecule with novel cellular effects. Nat. Biotechnol. 18:2000;304-308.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 304-308
    • Rosania, G.R.1
  • 23
    • 0034809353 scopus 로고    scopus 로고
    • Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product
    • Pelish H.E., et al. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product. J. Am. Chem. Soc. 123:2001;6740-6741.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 6740-6741
    • Pelish, H.E.1
  • 24
    • 0028505040 scopus 로고
    • Towards a pharmacological genetics
    • Mitchison T.J. Towards a pharmacological genetics. Chem. Biol. 1:1994;3-6.
    • (1994) Chem. Biol. , vol.1 , pp. 3-6
    • Mitchison, T.J.1
  • 25
    • 0032858094 scopus 로고    scopus 로고
    • Functional phage display of leech-derived tryptase inhibitor (LDTI): Construction of a library and selection of thrombin inhibitors
    • Tanaka A.S., et al. Functional phage display of leech-derived tryptase inhibitor (LDTI): construction of a library and selection of thrombin inhibitors. FEBS Lett. 458:1999;11-16.
    • (1999) FEBS Lett. , vol.458 , pp. 11-16
    • Tanaka, A.S.1
  • 26
    • 0034622925 scopus 로고    scopus 로고
    • Printing proteins as microarrays for high-throughput function determination
    • MacBeath G., Schreiber S.L. Printing proteins as microarrays for high-throughput function determination. Science. 289:2000;1760-1763.
    • (2000) Science , vol.289 , pp. 1760-1763
    • MacBeath, G.1    Schreiber, S.L.2
  • 27
    • 0029824170 scopus 로고    scopus 로고
    • A three-hybrid system for detecting small ligand-protein receptor interactions
    • Licitra E.J., Liu J.O. A three-hybrid system for detecting small ligand-protein receptor interactions. Proc. Natl. Acad. Sci. U. S. A. 93:1996;12817-12821.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 12817-12821
    • Licitra, E.J.1    Liu, J.O.2
  • 28
    • 0033048778 scopus 로고    scopus 로고
    • Genomic profiling of drug sensitivities via induced haploinsufficiency
    • Giaever G., et al. Genomic profiling of drug sensitivities via induced haploinsufficiency. Nat. Genet. 21:1999;278-283.
    • (1999) Nat. Genet. , vol.21 , pp. 278-283
    • Giaever, G.1
  • 29
    • 0031594985 scopus 로고    scopus 로고
    • Drug-induced phenotypes provide a tool for the functional analysis of yeast genes
    • Launhardt H., et al. Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. Yeast. 14:1998;935-942.
    • (1998) Yeast , vol.14 , pp. 935-942
    • Launhardt, H.1
  • 30
    • 85031190884 scopus 로고    scopus 로고
    • A chemistry-based approach to identify regulators of spindle assembly: Characterization of a microtubule destabilizing compound and target identification
    • Wignall S.M., et al. A chemistry-based approach to identify regulators of spindle assembly: Characterization of a microtubule destabilizing compound and target identification. Mol. Biol. Cell. 11:2000;361a.
    • (2000) Mol. Biol. Cell , vol.11
    • Wignall, S.M.1
  • 31
    • 0035931501 scopus 로고    scopus 로고
    • S-adenosylmethionine reverses ilimaquinone's vesiculation of the Golgi apparatus: A fluorescence study on the cellular interactions of ilimaquinone
    • Casaubon R.L., Snapper M.L. S-adenosylmethionine reverses ilimaquinone's vesiculation of the Golgi apparatus: a fluorescence study on the cellular interactions of ilimaquinone. Bioorg. Med. Chem. Lett. 11:2001;133-136.
    • (2001) Bioorg. Med. Chem. Lett. , vol.11 , pp. 133-136
    • Casaubon, R.L.1    Snapper, M.L.2
  • 32
    • 0033609044 scopus 로고    scopus 로고
    • A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts
    • Rosania G.R., et al. A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts. Proc. Natl. Acad. Sci. U. S. A. 96:1999;4797-4802.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 4797-4802
    • Rosania, G.R.1
  • 33
    • 0036884167 scopus 로고    scopus 로고
    • The use and analysis of microarray data
    • Butte A. The use and analysis of microarray data. Nat. Rev. Drug Discov. 1:2002;951-960.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 951-960
    • Butte, A.1
  • 34
    • 0031730097 scopus 로고    scopus 로고
    • Drug target validation and identification of secondary drug target effects using DNA microarrays
    • Marton M.J., et al. Drug target validation and identification of secondary drug target effects using DNA microarrays. Nat. Med. 4:1998;1293-1301.
    • (1998) Nat. Med. , vol.4 , pp. 1293-1301
    • Marton, M.J.1
  • 35
    • 0026009964 scopus 로고
    • Feedback control of mitosis in budding yeast
    • Li R., Murray A.W. Feedback control of mitosis in budding yeast. Cell. 66:1991;519-531.
    • (1991) Cell , vol.66 , pp. 519-531
    • Li, R.1    Murray, A.W.2
  • 36
    • 0025941405 scopus 로고
    • S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
    • Hoyt M.A., et al. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function. Cell. 66:1991;507-517.
    • (1991) Cell , vol.66 , pp. 507-517
    • Hoyt, M.A.1
  • 37
    • 0033961307 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the cell cycle
    • Crews C.M., Mohan R. Small-molecule inhibitors of the cell cycle. Curr. Opin. Chem. Biol. 4:2000;47-53.
    • (2000) Curr. Opin. Chem. Biol. , vol.4 , pp. 47-53
    • Crews, C.M.1    Mohan, R.2
  • 38
    • 0032858387 scopus 로고    scopus 로고
    • The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle
    • Theesfeld C.L., et al. The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle. J. Cell Biol. 146:1999;1019-1032.
    • (1999) J. Cell Biol. , vol.146 , pp. 1019-1032
    • Theesfeld, C.L.1
  • 39
    • 0036909567 scopus 로고    scopus 로고
    • Small molecules, big impact. A history of chemical inhibitors and the cytoskeleton
    • Peterson J.R., Mitchison T.J. Small molecules, big impact. A history of chemical inhibitors and the cytoskeleton. Chem. Biol. 9:2002;1275-1285.
    • (2002) Chem. Biol. , vol.9 , pp. 1275-1285
    • Peterson, J.R.1    Mitchison, T.J.2
  • 40
    • 0035910031 scopus 로고    scopus 로고
    • Identification of a small molecule inhibitor of Sir2p
    • Bedalov A., et al. Identification of a small molecule inhibitor of Sir2p. Proc. Natl. Acad. Sci. U. S. A. 98:2001;15113-15118.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 15113-15118
    • Bedalov, A.1
  • 41
    • 0033615357 scopus 로고    scopus 로고
    • Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
    • Mayer T.U., et al. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science. 286:1999;971-974.
    • (1999) Science , vol.286 , pp. 971-974
    • Mayer, T.U.1
  • 42
    • 0037436506 scopus 로고    scopus 로고
    • Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor
    • Straight A.F., et al. Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science. 299:2003;1743-1747.
    • (2003) Science , vol.299 , pp. 1743-1747
    • Straight, A.F.1
  • 43
    • 0029417238 scopus 로고
    • Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
    • Blangy A., et al. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell. 83:1995;1159-1169.
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1
  • 44
    • 0034605123 scopus 로고    scopus 로고
    • Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5
    • Kapoor T.M., et al. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J. Cell Biol. 150:2000;975-988.
    • (2000) J. Cell Biol. , vol.150 , pp. 975-988
    • Kapoor, T.M.1
  • 45
    • 0035904233 scopus 로고    scopus 로고
    • Eg5 is static in bipolar spindles relative to tubulin: Evidence for a static spindle matrix
    • Kapoor T.M., Mitchison T.J. Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix. J. Cell Biol. 154:2001;1125-1133.
    • (2001) J. Cell Biol. , vol.154 , pp. 1125-1133
    • Kapoor, T.M.1    Mitchison, T.J.2
  • 46
    • 0032101688 scopus 로고    scopus 로고
    • Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
    • Waters J.C., et al. Localization of Mad2 to kinetochores depends on microtubule attachment, not tension. J. Cell Biol. 141:1998;1181-1191.
    • (1998) J. Cell Biol. , vol.141 , pp. 1181-1191
    • Waters, J.C.1
  • 47
    • 0037428217 scopus 로고    scopus 로고
    • Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway
    • Jiang X., et al. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science. 299:2003;223-226.
    • (2003) Science , vol.299 , pp. 223-226
    • Jiang, X.1
  • 49
    • 0024117897 scopus 로고
    • Dissecting glycoprotein biosynthesis by the use of specific inhibitors
    • McDowell W., Schwarz R.T. Dissecting glycoprotein biosynthesis by the use of specific inhibitors. Biochimie. 70:1988;1535-1549.
    • (1988) Biochimie , vol.70 , pp. 1535-1549
    • McDowell, W.1    Schwarz, R.T.2
  • 50
    • 0037079065 scopus 로고    scopus 로고
    • Chemical genetic screening approaches to neurobiology
    • Stockwell B.R. Chemical genetic screening approaches to neurobiology. Neuron. 36:2002;559-562.
    • (2002) Neuron , vol.36 , pp. 559-562
    • Stockwell, B.R.1
  • 51
    • 0036669959 scopus 로고    scopus 로고
    • Using small molecules to study big questions in cellular microbiology
    • Ward G.E., et al. Using small molecules to study big questions in cellular microbiology. Cell Microbiol. 4:2002;471-482.
    • (2002) Cell Microbiol. , vol.4 , pp. 471-482
    • Ward, G.E.1
  • 52
    • 0036180246 scopus 로고    scopus 로고
    • A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells
    • Holt J.R., et al. A chemical-genetic strategy implicates myosin-1c in adaptation by hair cells. Cell. 108:2002;371-381.
    • (2002) Cell , vol.108 , pp. 371-381
    • Holt, J.R.1
  • 53
    • 0037133575 scopus 로고    scopus 로고
    • Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts
    • Berg T., et al. Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts. Proc. Natl. Acad. Sci. U. S. A. 99:2002;3830-3835.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 3830-3835
    • Berg, T.1
  • 54
    • 0035150803 scopus 로고    scopus 로고
    • Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL
    • Degterev A., et al. Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL. Nat. Cell Biol. 3:2001;173-182.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 173-182
    • Degterev, A.1
  • 55
    • 0036143029 scopus 로고    scopus 로고
    • A small-molecule inhibitor of skeletal muscle myosin II
    • Cheung A., et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat. Cell Biol. 4:2002;83-88.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 83-88
    • Cheung, A.1
  • 56
    • 0029166667 scopus 로고
    • A synthetic inhibitor of the mitogen-activated protein kinase cascade
    • Dudley D.T., et al. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7686-7689.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 7686-7689
    • Dudley, D.T.1
  • 57
    • 0033543728 scopus 로고    scopus 로고
    • A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
    • Komarov P.G., et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science. 285:1999;1733-1737.
    • (1999) Science , vol.285 , pp. 1733-1737
    • Komarov, P.G.1
  • 58
    • 0032504007 scopus 로고    scopus 로고
    • A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor
    • Tian S.S., et al. A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor. Science. 281:1998;257-259.
    • (1998) Science , vol.281 , pp. 257-259
    • Tian, S.S.1
  • 59
    • 0034177962 scopus 로고    scopus 로고
    • Dissecting cellular processes using small molecules: Identification of colchicine-like, taxol-like and other small molecules that perturb mitosis
    • Haggarty S.J., et al. Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis. Chem. Biol. 7:2000;275-286.
    • (2000) Chem. Biol. , vol.7 , pp. 275-286
    • Haggarty, S.J.1
  • 60
    • 0033564512 scopus 로고    scopus 로고
    • Eponemycin exerts its antitumor effect through the inhibition of proteasome function
    • Meng L., et al. Eponemycin exerts its antitumor effect through the inhibition of proteasome function. Cancer Res. 59:1999;2798-2801.
    • (1999) Cancer Res. , vol.59 , pp. 2798-2801
    • Meng, L.1
  • 61
    • 0030924753 scopus 로고    scopus 로고
    • The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
    • Sin N., et al. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2. Proc. Natl. Acad. Sci. U. S. A. 94:1997;6099-6103.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 6099-6103
    • Sin, N.1
  • 62
    • 0031684679 scopus 로고    scopus 로고
    • Photoaffinity study of the cellular interactions of ilimaquinone
    • Radeke H.S., Snapper M.L. Photoaffinity study of the cellular interactions of ilimaquinone. Bioorg. Med. Chem. 6:1998;1227-1232.
    • (1998) Bioorg. Med. Chem. , vol.6 , pp. 1227-1232
    • Radeke, H.S.1    Snapper, M.L.2
  • 63
    • 0029932598 scopus 로고    scopus 로고
    • A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
    • Taunton J., et al. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science. 272:1996;408-411.
    • (1996) Science , vol.272 , pp. 408-411
    • Taunton, J.1
  • 64
    • 0029033981 scopus 로고
    • Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
    • Fenteany G., et al. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science. 268:1995;726-731.
    • (1995) Science , vol.268 , pp. 726-731
    • Fenteany, G.1
  • 65
    • 0024472603 scopus 로고
    • A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase
    • Harding M.W., et al. A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase. Nature. 341:1989;758-760.
    • (1989) Nature , vol.341 , pp. 758-760
    • Harding, M.W.1
  • 66
    • 0031678366 scopus 로고    scopus 로고
    • Peptide and peptidomimetic libraries. Molecular diversity and drug design
    • Ab-Obeidi F., et al. Peptide and peptidomimetic libraries. Molecular diversity and drug design. Mol. Biotechnol. 9:1998;205-223.
    • (1998) Mol. Biotechnol. , vol.9 , pp. 205-223
    • Ab-Obeidi, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.