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Volumn 16, Issue 4, 2002, Pages 623-637

Hypothalamic regulation of energy homeostasis

Author keywords

AgRP; CART; Energy expenditure; Energy intake; Hormone output; Hypothalamus; NPY; MSH

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; GHRELIN; GLUCOCORTICOID; HORMONE; INSULIN; LEPTIN; LIPID; MELANOCORTIN 4 RECEPTOR; NEUROPEPTIDE; NEUROPEPTIDE Y; ANOREXIGENIC AGENT; APPETITE STIMULANT; MELANOCORTIN;

EID: 12244265510     PISSN: 1521690X     EISSN: None     Source Type: Journal    
DOI: 10.1053/beem.2002.0230     Document Type: Review
Times cited : (115)

References (104)
  • 2
    • 0032577404 scopus 로고    scopus 로고
    • Environmental contributions to the obesity epidemic
    • Hill JO & Peters JC. Environmental contributions to the obesity epidemic. Science 1998; 280: 1371-1374.
    • (1998) Science , vol.280 , pp. 1371-1374
    • Hill, J.O.1    Peters, J.C.2
  • 3
    • 0024241717 scopus 로고
    • Thermogenesis after lateral hypothalamic lesions: Contributions of brown adipose tissue
    • Corbett SW, Kaufman LN & Keesey RE. Thermogenesis after lateral hypothalamic lesions: Contributions of brown adipose tissue. American Journal of Physiology 1988; 255: E708-E715.
    • (1988) American Journal of Physiology , vol.255
    • Corbett, S.W.1    Kaufman, L.N.2    Keesey, R.E.3
  • 4
    • 0035851851 scopus 로고    scopus 로고
    • The hypothalamus and the control of energy homeostasis: Different circuits, different purposes
    • Williams G, Bing C, Cai XJ et al. The hypothalamus and the control of energy homeostasis: Different circuits, different purposes. Physiology and Behavior 2001; 74: 683-701.
    • (2001) Physiology and Behavior , vol.74 , pp. 683-701
    • Williams, G.1    Bing, C.2    Cai, X.J.3
  • 5
    • 0015132483 scopus 로고
    • Neural pathways involved in the ventromedial hypothalamic lesion syndrome in the rat
    • Sclafani A. Neural pathways involved in the ventromedial hypothalamic lesion syndrome in the rat. Journal of Comparative and Physiological Psychology 1971; 77: 70-96.
    • (1971) Journal of Comparative and Physiological Psychology , vol.77 , pp. 70-96
    • Sclafani, A.1
  • 6
    • 0020149519 scopus 로고
    • Gold thioglucose-induced hypothalamic damage, hyperphagia, and obesity: Dependence on the adrenal gland
    • Debons AF, Siclari E, Das KC et al. Gold thioglucose-induced hypothalamic damage, hyperphagia, and obesity: Dependence on the adrenal gland. Endocrinology 1982; 110: 2024-2029.
    • (1982) Endocrinology , vol.110 , pp. 2024-2029
    • Debons, A.F.1    Siclari, E.2    Das, K.C.3
  • 7
    • 0022515464 scopus 로고
    • In vivo metabolic changes as studied longitudinally after ventromedial hypothalamic lesions
    • Penicaud L, Rohner-Jeanrenaud F & Jeanrenaud B. In vivo metabolic changes as studied longitudinally after ventromedial hypothalamic lesions. American Journal of Physiology 1986; 250: E662-E668.
    • (1986) American Journal of Physiology , vol.250
    • Penicaud, L.1    Rohner-Jeanrenaud, F.2    Jeanrenaud, B.3
  • 8
    • 0024158305 scopus 로고
    • Sympathetic activity following paraventricular or ventromedial hypothalamic lesions in rats
    • Sakaguchi T, Bray GA & Eddlestone G. Sympathetic activity following paraventricular or ventromedial hypothalamic lesions in rats. Brain Research Bulletin 1988; 20: 461-465.
    • (1988) Brain Research Bulletin , vol.20 , pp. 461-465
    • Sakaguchi, T.1    Bray, G.A.2    Eddlestone, G.3
  • 10
    • 0033497369 scopus 로고    scopus 로고
    • Hypothalamic obesity caused by cranial insult in children: Altered glucose and insulin dynamics and reversal by a somatostatin agonist
    • Lustig RH, Rose SR, Burghen GA et al. Hypothalamic obesity caused by cranial insult in children: Altered glucose and insulin dynamics and reversal by a somatostatin agonist. Journal of Pediatrics 1999; 135: 162-168.
    • (1999) Journal of Pediatrics , vol.135 , pp. 162-168
    • Lustig, R.H.1    Rose, S.R.2    Burghen, G.A.3
  • 11
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM & Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 12
    • 0027319108 scopus 로고
    • Increased neuropeptide-Y messenger and decreased neurotensin messenger RNA in the hypothalamus of the obese (ob/ob) mouse
    • Wilding JPH, Gilbey SG, Bailey CJ et al. Increased neuropeptide-Y messenger and decreased neurotensin messenger RNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 1993; 132: 1939-1944.
    • (1993) Endocrinology , vol.132 , pp. 1939-1944
    • Wilding, J.P.H.1    Gilbey, S.G.2    Bailey, C.J.3
  • 13
    • 0032879096 scopus 로고    scopus 로고
    • Neuropeptide Y overexpression in the preweanling Zucker (fa/fa) rat
    • Kowalski TJ, Houpt TA, Jahng J et al. Neuropeptide Y overexpression in the preweanling Zucker (fa/fa) rat. Physiology and Behavior 1999; 67: 521-525.
    • (1999) Physiology and Behavior , vol.67 , pp. 521-525
    • Kowalski, T.J.1    Houpt, T.A.2    Jahng, J.3
  • 15
    • 0030878110 scopus 로고    scopus 로고
    • Congenital leptin deficiency is associated with severe early-onset obesity in humans
    • Montague CT, Farooqi IS, Whitehead JP et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997; 387: 903-908.
    • (1997) Nature , vol.387 , pp. 903-908
    • Montague, C.T.1    Farooqi, I.S.2    Whitehead, J.P.3
  • 16
    • 0343953074 scopus 로고    scopus 로고
    • Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
    • Farooqi IS, Yeo GS, Keogh JM et al. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. Journal of Clinical Investigation 2000; 106: 271-279.
    • (2000) Journal of Clinical Investigation , vol.106 , pp. 271-279
    • Farooqi, I.S.1    Yeo, G.S.2    Keogh, J.M.3
  • 17
    • 0030889192 scopus 로고    scopus 로고
    • Targeted disruption of the melanocortin-4 receptor results in obesity in mice
    • Huszar D, Lynch CA, Fairchild-Huntress V et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997; 88: 131-141.
    • (1997) Cell , vol.88 , pp. 131-141
    • Huszar, D.1    Lynch, C.A.2    Fairchild-Huntress, V.3
  • 18
    • 0032863468 scopus 로고    scopus 로고
    • Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
    • Yaswen L, Diehl N, Brennan MB et al. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nature Medicine 1999; 5: 1066-1070.
    • (1999) Nature Medicine , vol.5 , pp. 1066-1070
    • Yaswen, L.1    Diehl, N.2    Brennan, M.B.3
  • 19
    • 0029946644 scopus 로고    scopus 로고
    • Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
    • Erickson JC, Clegg KE & Palmiter RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 1996; 381: 415-418.
    • (1996) Nature , vol.381 , pp. 415-418
    • Erickson, J.C.1    Clegg, K.E.2    Palmiter, R.D.3
  • 20
    • 0029804743 scopus 로고    scopus 로고
    • Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
    • Ericksson JC, Hollopeter G & Palmiter RD. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 1996; 274: 1704-1707.
    • (1996) Science , vol.274 , pp. 1704-1707
    • Ericksson, J.C.1    Hollopeter, G.2    Palmiter, R.D.3
  • 21
    • 0031779479 scopus 로고    scopus 로고
    • Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor
    • Pedrazzini T, Seydoux J, Kunstner P et al. Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor. Nature Medicine 1998; 4: 722-726.
    • (1998) Nature Medicine , vol.4 , pp. 722-726
    • Pedrazzini, T.1    Seydoux, J.2    Kunstner, P.3
  • 23
    • 0032861562 scopus 로고    scopus 로고
    • Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor
    • Naveilhan P, Hassani H, Canals JM et al. Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor. Nature Medicine 1999; 5: 1188-1193.
    • (1999) Nature Medicine , vol.5 , pp. 1188-1193
    • Naveilhan, P.1    Hassani, H.2    Canals, J.M.3
  • 24
    • 0037173035 scopus 로고    scopus 로고
    • Important role of hypothalamic Y2 receptors in bodyweight regulation revealed in conditional knockout mice
    • Sainsbury A, Schwarzer C, Couzens M et al. Important role of hypothalamic Y2 receptors in bodyweight regulation revealed in conditional knockout mice. Proceedings of the National Academy of Sciences of the USA 2002: 99: 8938-8943.
    • (2002) Proceedings of the National Academy of Sciences of the USA , vol.99 , pp. 8938-8943
    • Sainsbury, A.1    Schwarzer, C.2    Couzens, M.3
  • 25
    • 0031779336 scopus 로고    scopus 로고
    • Role of the Y5 neuropeptide Y receptor in feeding and obesity
    • Marsh DJ, Hollopeter G, Kafer KE et al. Role of the Y5 neuropeptide Y receptor in feeding and obesity. Nature Medicine 1998; 4: 718-721.
    • (1998) Nature Medicine , vol.4 , pp. 718-721
    • Marsh, D.J.1    Hollopeter, G.2    Kafer, K.E.3
  • 26
    • 0036288345 scopus 로고    scopus 로고
    • Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice
    • Qian S, Chen H, Weingarth D et al. Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice. Molecular and Cell Biology 2002; 22: 5027-5035.
    • (2002) Molecular and Cell Biology , vol.22 , pp. 5027-5035
    • Qian, S.1    Chen, H.2    Weingarth, D.3
  • 27
    • 0030062356 scopus 로고    scopus 로고
    • Expression cloning of a human brain neuropeptide Y Y2 receptor
    • Gehlert DR, Beavers LS, Johnson D et al. Expression cloning of a human brain neuropeptide Y Y2 receptor. Molecular Pharmacology 1996; 49: 224-228.
    • (1996) Molecular Pharmacology , vol.49 , pp. 224-228
    • Gehlert, D.R.1    Beavers, L.S.2    Johnson, D.3
  • 28
    • 0037043704 scopus 로고    scopus 로고
    • Gut hormone PYY3-36 physiologically inhibits food intake
    • Batterham RJ, Cowley MA, Small CJ et al. Gut hormone PYY3-36 physiologically inhibits food intake. Nature 2002; 418: 650-654.
    • (2002) Nature , vol.418 , pp. 650-654
    • Batterham, R.J.1    Cowley, M.A.2    Small, C.J.3
  • 29
    • 0018671876 scopus 로고
    • Distribution of alpha-melanocyte-stimulating hormone in the rat brain: Evidence, that alpha-MSH-containing cells in the arcuate region send projections to extrahypothalamic areas
    • Eskay RL, Giraud P, Oliver C et al. Distribution of alpha-melanocyte-stimulating hormone in the rat brain: Evidence, that alpha-MSH-containing cells in the arcuate region send projections to extrahypothalamic areas. Brain Research 1979; 178: 55-67.
    • (1979) Brain Research , vol.178 , pp. 55-67
    • Eskay, R.L.1    Giraud, P.2    Oliver, C.3
  • 30
    • 0030764741 scopus 로고    scopus 로고
    • Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
    • [published erratum appears in Science 1998; 281:1615]
    • Ollmann MM, Wilson BD, Yang YK et al. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein [published erratum appears in Science 1998; 281:1615]. Science 1997; 278: 135-138.
    • (1997) Science , vol.278 , pp. 135-138
    • Ollmann, M.M.1    Wilson, B.D.2    Yang, Y.K.3
  • 31
    • 0017276160 scopus 로고
    • Entry of peroxidase into neurons of the central and peripheral nervous systems for extracerebral and cerebral blood
    • Broadwell RD & Brightman MW. Entry of peroxidase into neurons of the central and peripheral nervous systems for extracerebral and cerebral blood. Journal of Comparative Neuroanatomy 1976; 166: 257-283.
    • (1976) Journal of Comparative Neuroanatomy , vol.166 , pp. 257-283
    • Broadwell, R.D.1    Brightman, M.W.2
  • 33
    • 0023733376 scopus 로고
    • Localization of glucocorticoid receptor in neuropeptide Y-containing neurons in the arcuate nucleus of the rat hypothalamus
    • Hisano S, Kagotani Y, Tsuruo Y et al. Localization of glucocorticoid receptor in neuropeptide Y-containing neurons in the arcuate nucleus of the rat hypothalamus. Neuroscience Letters 1988; 95: 13-18.
    • (1988) Neuroscience Letters , vol.95 , pp. 13-18
    • Hisano, S.1    Kagotani, Y.2    Tsuruo, Y.3
  • 34
    • 0025612094 scopus 로고
    • Localization of insulin receptor mRNA in rat brain by in situ hybridization
    • Marks JL, Porte DJ, Stahl WL et al. Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology 1990; 127: 3234-3236.
    • (1990) Endocrinology , vol.127 , pp. 3234-3236
    • Marks, J.L.1    Porte, D.J.2    Stahl, W.L.3
  • 35
    • 0030829873 scopus 로고    scopus 로고
    • Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus
    • Broberger C, Landry M, Wong H et al. Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus. Neuroendocrinology 1997; 66: 393-408.
    • (1997) Neuroendocrinology , vol.66 , pp. 393-408
    • Broberger, C.1    Landry, M.2    Wong, H.3
  • 37
    • 0022588106 scopus 로고
    • Evidence for different pre- and post-junctional receptors for neuropeptide Y and related peptides
    • Wahlestedt C, Yanaihara N & Hakanson R. Evidence for different pre- and post-junctional receptors for neuropeptide Y and related peptides. Regulatory Peptides 1986; 13: 307-318.
    • (1986) Regulatory Peptides , vol.13 , pp. 307-318
    • Wahlestedt, C.1    Yanaihara, N.2    Hakanson, R.3
  • 38
    • 0032130554 scopus 로고    scopus 로고
    • Coexpression of AGRP and NPY in fasting-activated hypothalamic neurons
    • Hahn TM, Breininger JF, Baskin DG et al. Coexpression of AGRP and NPY in fasting-activated hypothalamic neurons. Nature Neuroscience 1998; 1: 271-272.
    • (1998) Nature Neuroscience , vol.1 , pp. 271-272
    • Hahn, T.M.1    Breininger, J.F.2    Baskin, D.G.3
  • 39
    • 0030893647 scopus 로고    scopus 로고
    • Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice
    • Shutter JR, Graham M, Kinsey AC et al. Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice. Genes & Development 1997; 11: 593-602.
    • (1997) Genes & Development , vol.11 , pp. 593-602
    • Shutter, J.R.1    Graham, M.2    Kinsey, A.C.3
  • 40
    • 0033040237 scopus 로고    scopus 로고
    • Regional distribution of Y-receptor subtype mRNAs in rat brain
    • Parker RM & Herzog H. Regional distribution of Y-receptor subtype mRNAs in rat brain. European Journal of Neuroscience 1999; 11: 1431-1448.
    • (1999) European Journal of Neuroscience , vol.11 , pp. 1431-1448
    • Parker, R.M.1    Herzog, H.2
  • 41
    • 0025897414 scopus 로고
    • Arcuate nucleus projections to brainstem regions which modulate nociception
    • Sim LJ & Joseph SA. Arcuate nucleus projections to brainstem regions which modulate nociception. Journal of Chemical Neuroanatomy 1991; 4: 97-109.
    • (1991) Journal of Chemical Neuroanatomy , vol.4 , pp. 97-109
    • Sim, L.J.1    Joseph, S.A.2
  • 42
    • 0029099078 scopus 로고
    • Arcuate nucleus neurons that project to the hypothalamic paraventricular nucleus: Neuropeptidergic identity and consequences of adrenalectomy on mRNA levels in the rat
    • Baker RA & Herkenham M. Arcuate nucleus neurons that project to the hypothalamic paraventricular nucleus: Neuropeptidergic identity and consequences of adrenalectomy on mRNA levels in the rat. Journal of Comparative Neuroanatomy 1995; 358: 518-530.
    • (1995) Journal of Comparative Neuroanatomy , vol.358 , pp. 518-530
    • Baker, R.A.1    Herkenham, M.2
  • 43
    • 0035096466 scopus 로고    scopus 로고
    • Inhibitory effects of central neuropeptide Y on the somatotropic and gonadotropic axes in male rats are independent of adrenal hormones
    • Sainsbury A & Herzog H. Inhibitory effects of central neuropeptide Y on the somatotropic and gonadotropic axes in male rats are independent of adrenal hormones. Peptides 2001; 22: 467-471.
    • (2001) Peptides , vol.22 , pp. 467-471
    • Sainsbury, A.1    Herzog, H.2
  • 44
    • 0032443807 scopus 로고    scopus 로고
    • The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
    • Broberger C, Johansen J, Johansson C et al. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proceedings of the National Academy of Sciences of the USA 1998; 95: 15 043-15 048.
    • (1998) Proceedings of the National Academy of Sciences of the USA , vol.95 , pp. 15043-15048
    • Broberger, C.1    Johansen, J.2    Johansson, C.3
  • 45
    • 0028116136 scopus 로고
    • c-fos expression in the rat brain following central administration of neuropeptide Y and effects of food consumption
    • Li BH, Xu B, Rowland NE et al. c-fos expression in the rat brain following central administration of neuropeptide Y and effects of food consumption. Brain Research 1994; 665: 277-284.
    • (1994) Brain Research , vol.665 , pp. 277-284
    • Li, B.H.1    Xu, B.2    Rowland, N.E.3
  • 46
    • 0027450918 scopus 로고
    • The perifornical area: The major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s)
    • Stanley BG, Magdalin W, Seirafi A et al. The perifornical area: The major focus of (a) patchily distributed hypothalamic neuropeptide Y-sensitive feeding system(s). Brain Research 1993; 604: 304-317.
    • (1993) Brain Research , vol.604 , pp. 304-317
    • Stanley, B.G.1    Magdalin, W.2    Seirafi, A.3
  • 47
    • 0001860773 scopus 로고
    • The MONA LISA hypothesis. Most obesities known are low in sympathetic activity
    • In Oomura Y, Tarui, S Inoue S & Shimazu T (eds); London: John Libbey and Company Ltd
    • Bray GA. The MONA LISA hypothesis. Most obesities known are low in sympathetic activity. In Oomura Y, Tarui, S Inoue S & Shimazu T (eds) Progress in Obesity Research 1990; pp 61-66. London: John Libbey and Company Ltd, 1990.
    • (1990) Progress in Obesity Research 1990 , pp. 61-66
    • Bray, G.A.1
  • 48
    • 0025314708 scopus 로고
    • Metabolic effects of neuropeptide Y injections into the paraventricular nucleus of the hypothalamus
    • Menendez JA, McGregor IS, Healey PA et al. Metabolic effects of neuropeptide Y injections into the paraventricular nucleus of the hypothalamus. Brain Research 1990; 516: 8-14.
    • (1990) Brain Research , vol.516 , pp. 8-14
    • Menendez, J.A.1    McGregor, I.S.2    Healey, P.A.3
  • 49
    • 0032703393 scopus 로고    scopus 로고
    • Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouse
    • Broberger C, Visser TJ, Kuhar MJ et al. Neuropeptide Y innervation and neuropeptide-Y-Y1-receptor-expressing neurons in the paraventricular hypothalamic nucleus of the mouse. Neuroendocrinology 1999; 70: 295-305.
    • (1999) Neuroendocrinology , vol.70 , pp. 295-305
    • Broberger, C.1    Visser, T.J.2    Kuhar, M.J.3
  • 50
    • 0032566817 scopus 로고    scopus 로고
    • Segregation of the intra- and extrahypothalamic neuropeptide Y and catecholaminergic inputs on paraventricular neurons, including those producing thyrotropin-releasing hormone
    • Diano S, Naftolin F, Goglia F et al. Segregation of the intra- and extrahypothalamic neuropeptide Y and catecholaminergic inputs on paraventricular neurons, including those producing thyrotropin-releasing hormone. Regulatory Peptides 1998; 75-76: 117-126.
    • (1998) Regulatory Peptides , vol.75-76 , pp. 117-126
    • Diano, S.1    Naftolin, F.2    Goglia, F.3
  • 51
    • 0342858793 scopus 로고    scopus 로고
    • Alpha-melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression
    • Fekete C, Legradi G, Mihaly E et al. Alpha-melanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression. Journal of Neuroscience 2000; 20: 1550-1558.
    • (2000) Journal of Neuroscience , vol.20 , pp. 1550-1558
    • Fekete, C.1    Legradi, G.2    Mihaly, E.3
  • 52
    • 0029860452 scopus 로고    scopus 로고
    • Multiple NPY receptors coexist in pre- and postsynaptic sites: Inhibition of GABA release in isolated self-innervating SCN neurons
    • Chen G & Van Den Pol AN. Multiple NPY receptors coexist in pre- and postsynaptic sites: Inhibition of GABA release in isolated self-innervating SCN neurons. Journal of Neuroscience 1996; 16: 7711-7724.
    • (1996) Journal of Neuroscience , vol.16 , pp. 7711-7724
    • Chen, G.1    Van Den Pol, A.N.2
  • 53
    • 0032576592 scopus 로고    scopus 로고
    • Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
    • Elias CF, Saper CB, Maratos-Flier E et al. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. Journal of Comparative Neurology 1998; 402: 442-459.
    • (1998) Journal of Comparative Neurology , vol.402 , pp. 442-459
    • Elias, C.F.1    Saper, C.B.2    Maratos-Flier, E.3
  • 54
    • 0022873040 scopus 로고
    • Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity
    • Stanley BG, Kyrkouli SE, Lampert S et al. Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity. Peptides 1986; 7: 1189-1192.
    • (1986) Peptides , vol.7 , pp. 1189-1192
    • Stanley, B.G.1    Kyrkouli, S.E.2    Lampert, S.3
  • 55
    • 0033870091 scopus 로고    scopus 로고
    • Long-term orexigenic effects of AgRP-(83-132) involve mechanisms other than melanocortin receptor blockade
    • Hagan MM, Rushing PA, Pritchard LM et al. Long-term orexigenic effects of AgRP-(83-132) involve mechanisms other than melanocortin receptor blockade. American Journal of Physiology 2000; 279: R47-R52.
    • (2000) American Journal of Physiology , vol.279
    • Hagan, M.M.1    Rushing, P.A.2    Pritchard, L.M.3
  • 56
    • 0000573907 scopus 로고    scopus 로고
    • Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone
    • Kim MS, Rossi M, Abusnana S et al. Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone. Diabetes 2000; 49: 177-182.
    • (2000) Diabetes , vol.49 , pp. 177-182
    • Kim, M.S.1    Rossi, M.2    Abusnana, S.3
  • 57
    • 0033577175 scopus 로고    scopus 로고
    • Long-term administration of MC4 receptor antagonist HS014 causes hyperphagia and obesity in rats
    • Kask A, Pahkla R, Irs A et al. Long-term administration of MC4 receptor antagonist HS014 causes hyperphagia and obesity in rats. Neuroreport 1999; 10: 707-711.
    • (1999) Neuroreport , vol.10 , pp. 707-711
    • Kask, A.1    Pahkla, R.2    Irs, A.3
  • 58
    • 0031914232 scopus 로고    scopus 로고
    • Central infusion of melanocortin agonist MTII in rats: Assessment of c-Fos expression and taste aversion
    • Thiele TE, Van Dijk G, Yagaloff KA et al. Central infusion of melanocortin agonist MTII in rats: Assessment of c-Fos expression and taste aversion. American Journal of Physiology 1998; 274: R248-R254.
    • (1998) American Journal of Physiology , vol.274
    • Thiele, T.E.1    Van Dijk, G.2    Yagaloff, K.A.3
  • 59
    • 0032583131 scopus 로고    scopus 로고
    • Central injection in rats of alpha-melanocyte-stimulating hormone analog: Effects on food intake and brain Fos
    • Brown KS, Gentry RM & Rowland NE. Central injection in rats of alpha-melanocyte-stimulating hormone analog: Effects on food intake and brain Fos. Regulatory Peptides 1998; 78: 89-94.
    • (1998) Regulatory Peptides , vol.78 , pp. 89-94
    • Brown, K.S.1    Gentry, R.M.2    Rowland, N.E.3
  • 60
    • 0032492893 scopus 로고    scopus 로고
    • Hypothalamic CART is a new anorectic peptide regulated by leptin
    • Kristensen P, Judge ME, Thim L et al. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 1998; 393: 72-76.
    • (1998) Nature , vol.393 , pp. 72-76
    • Kristensen, P.1    Judge, M.E.2    Thim, L.3
  • 61
    • 0034331561 scopus 로고    scopus 로고
    • Chronic intracerebroventricular administration of recombinant CART(42-89) peptide inhibits and causes weight loss in lean and obese Zucker (fa/fa) rats
    • Larsen PJ, Vrang N, Petersen PC et al. Chronic intracerebroventricular administration of recombinant CART(42-89) peptide inhibits and causes weight loss in lean and obese Zucker (fa/fa) rats. Obesity Research 2000; 8: 590-596.
    • (2000) Obesity Research , vol.8 , pp. 590-596
    • Larsen, P.J.1    Vrang, N.2    Petersen, P.C.3
  • 62
    • 0029023938 scopus 로고
    • A neuroendocrine reappraisal of the dual-centre hypothesis: Its implications for obesity and insulin resistance
    • Rohner-Jeanrenaud F. A neuroendocrine reappraisal of the dual-centre hypothesis: Its implications for obesity and insulin resistance. International Journal of Obesity 1995; 19: 517-534.
    • (1995) International Journal of Obesity , vol.19 , pp. 517-534
    • Rohner-Jeanrenaud, F.1
  • 63
    • 0024817608 scopus 로고
    • Effects of corticotropin-releasing factor on energy balance in rats are sex dependent
    • Rivest S, Deshaies Y & Richard D. Effects of corticotropin-releasing factor on energy balance in rats are sex dependent. American Journal of Physiology 1989; 257: R1417-R1422.
    • (1989) American Journal of Physiology , vol.257
    • Rivest, S.1    Deshaies, Y.2    Richard, D.3
  • 64
    • 0027362079 scopus 로고
    • Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity
    • Zarjevski N, Cusin I, Vettor R et al. Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity. Endocrinology 1993; 133: 1753-1758.
    • (1993) Endocrinology , vol.133 , pp. 1753-1758
    • Zarjevski, N.1    Cusin, I.2    Vettor, R.3
  • 65
    • 0035142129 scopus 로고    scopus 로고
    • Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals
    • Small CJ, Kim MS, Stanley SA et al. Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals. Diabetes 2001; 50: 248-254.
    • (2001) Diabetes , vol.50 , pp. 248-254
    • Small, C.J.1    Kim, M.S.2    Stanley, S.A.3
  • 66
    • 0036096230 scopus 로고    scopus 로고
    • The leptin-like effects of 3-d peripheral administration of a melanocortin agonist are more marked in genetically obese Zucker (fa/fa) than in lean rats
    • Cettour-Rose P & Rohner-Jeanrenaud F. The leptin-like effects of 3-d peripheral administration of a melanocortin agonist are more marked in genetically obese Zucker (fa/fa) than in lean rats. Endocrinology 2002; 143: 2277-2283.
    • (2002) Endocrinology , vol.143 , pp. 2277-2283
    • Cettour-Rose, P.1    Rohner-Jeanrenaud, F.2
  • 67
    • 0034998139 scopus 로고    scopus 로고
    • Neuropeptide Y has a central inhibitory action on the hypothalamic-pituitary-thyroid axis
    • Fekete C, Kelly J, Mihaly E et al. Neuropeptide Y has a central inhibitory action on the hypothalamic-pituitary-thyroid axis. Endocrinology 2001; 142: 2606-2613.
    • (2001) Endocrinology , vol.142 , pp. 2606-2613
    • Fekete, C.1    Kelly, J.2    Mihaly, E.3
  • 68
    • 0034037278 scopus 로고    scopus 로고
    • The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin
    • Kim MS, Small CJ, Stanley SA et al. The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin. Journal of Clinical Investigation 2000; 105: 1005-1011.
    • (2000) Journal of Clinical Investigation , vol.105 , pp. 1005-1011
    • Kim, M.S.1    Small, C.J.2    Stanley, S.A.3
  • 69
    • 0033304761 scopus 로고    scopus 로고
    • Agouti-related protein containing nerve terminals innervate thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus
    • Legradi G & Lechan RM. Agouti-related protein containing nerve terminals innervate thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 1999; 140: 3643-3652.
    • (1999) Endocrinology , vol.140 , pp. 3643-3652
    • Legradi, G.1    Lechan, R.M.2
  • 70
    • 0031730916 scopus 로고    scopus 로고
    • The arcuate nucleus is the major source for neuropeptide Y-innervation of thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus
    • Legradi G & Lechan RM. The arcuate nucleus is the major source for neuropeptide Y-innervation of thyrotropin-releasing hormone neurons in the hypothalamic paraventricular nucleus. Endocrinology 1998; 139: 3262-3270.
    • (1998) Endocrinology , vol.139 , pp. 3262-3270
    • Legradi, G.1    Lechan, R.M.2
  • 71
    • 0035793941 scopus 로고    scopus 로고
    • Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats
    • Stanley SA, Small CJ, Murphy KG et al. Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Research 2001; 893: 186-194.
    • (2001) Brain Research , vol.893 , pp. 186-194
    • Stanley, S.A.1    Small, C.J.2    Murphy, K.G.3
  • 72
    • 0028009479 scopus 로고
    • Thermoregulatory effect of intracerebral injections of neuropeptide Y in rats at different environmental temperatures
    • Szreder Z, Hori T & Kaizuka Y. Thermoregulatory effect of intracerebral injections of neuropeptide Y in rats at different environmental temperatures. General Pharmacology 1994; 25: 85-91.
    • (1994) General Pharmacology , vol.25 , pp. 85-91
    • Szreder, Z.1    Hori, T.2    Kaizuka, Y.3
  • 73
    • 0029001753 scopus 로고
    • Dissociated feeding and hypothermic effects of neuropeptide Y in the paraventricular and perifornical hypothalamus
    • Currie PJ & Coscina DV. Dissociated feeding and hypothermic effects of neuropeptide Y in the paraventricular and perifornical hypothalamus. Peptides 1995; 16: 599-604.
    • (1995) Peptides , vol.16 , pp. 599-604
    • Currie, P.J.1    Coscina, D.V.2
  • 74
    • 0032805933 scopus 로고    scopus 로고
    • Activation of the NPYY5 receptor regulates both feeding and energy expenditure
    • Hwa JJ, Witten MB, Williams P et al. Activation of the NPYY5 receptor regulates both feeding and energy expenditure. American Journal of Physiology 1999; 277: R1428-R1434.
    • (1999) American Journal of Physiology , vol.277
    • Hwa, J.J.1    Witten, M.B.2    Williams, P.3
  • 75
    • 0031846668 scopus 로고    scopus 로고
    • Divergence of the feeding and thermogenic pathways influenced by NPY in the hypothalamic PVn of the rat
    • Kotz CM, Briggs JE, Grace MK et al. Divergence of the feeding and thermogenic pathways influenced by NPY in the hypothalamic PVn of the rat. American Journal of Physiology 1998; 44: R471-R477.
    • (1998) American Journal of Physiology , vol.44
    • Kotz, C.M.1    Briggs, J.E.2    Grace, M.K.3
  • 76
    • 0026061245 scopus 로고
    • Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats
    • Egawa M, Yoshimatsu H & Bray GA. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats. American Journal of Physiology 1991; 260: R328-R334.
    • (1991) American Journal of Physiology , vol.260
    • Egawa, M.1    Yoshimatsu, H.2    Bray, G.A.3
  • 78
    • 0036097363 scopus 로고    scopus 로고
    • Chronic central melanocortin-4 receptor antagonist and central neuropeptide-y infusion in rats produce increased adiposity by divergent pathways
    • Baran K, Preston E, Wilks D et al. Chronic central melanocortin-4 receptor antagonist and central neuropeptide-y infusion in rats produce increased adiposity by divergent pathways. Diabetes 2002; 51: 152-158.
    • (2002) Diabetes , vol.51 , pp. 152-158
    • Baran, K.1    Preston, E.2    Wilks, D.3
  • 79
    • 0033926927 scopus 로고    scopus 로고
    • Centrally administered MTII affects feeding, drinking, temperature, and activity in the Sprague-Dawley rat
    • Murphy B, Nunes CN, Ronan JJ et al. Centrally administered MTII affects feeding, drinking, temperature, and activity in the Sprague-Dawley rat. Journal of Applied Physiology 2000; 89: 273-282.
    • (2000) Journal of Applied Physiology , vol.89 , pp. 273-282
    • Murphy, B.1    Nunes, C.N.2    Ronan, J.J.3
  • 80
    • 0036515969 scopus 로고    scopus 로고
    • Chronic application of MTII in a rat model of obesity results in sustained weight loss
    • Hamilton BS & Doods HN. Chronic application of MTII in a rat model of obesity results in sustained weight loss. Obesity Research 2002; 10: 182-187.
    • (2002) Obesity Research , vol.10 , pp. 182-187
    • Hamilton, B.S.1    Doods, H.N.2
  • 81
    • 0034727445 scopus 로고    scopus 로고
    • Effect of CART in the hypothalamic paraventricular nucleus on feeding and uncoupling protein gene expression
    • Wang C, Billington CJ, Levine AS et al. Effect of CART in the hypothalamic paraventricular nucleus on feeding and uncoupling protein gene expression. Neuroreport 2000; 11: 3251-3255.
    • (2000) Neuroreport , vol.11 , pp. 3251-3255
    • Wang, C.1    Billington, C.J.2    Levine, A.S.3
  • 82
    • 85047697803 scopus 로고    scopus 로고
    • Chronic central infusion of cocaine- and amphetamine-regulated transcript (CART 55-102): Effects on body weight homeostasis in lean and high-fat-fed obese rats
    • Rohner-Jeanrenaud F, Craft LS, Bridwell J et al. Chronic central infusion of cocaine- and amphetamine-regulated transcript (CART 55-102): Effects on body weight homeostasis in lean and high-fat-fed obese rats. International Journal of Obesity 2002; 26: 143-149.
    • (2002) International Journal of Obesity , vol.26 , pp. 143-149
    • Rohner-Jeanrenaud, F.1    Craft, L.S.2    Bridwell, J.3
  • 83
    • 0034806985 scopus 로고    scopus 로고
    • Cocaine-amphetamine-regulated transcript influences energy metabolism, anxiety and gastric emptying in mice
    • Asakawa A, Inui A, Yuzuriha H et al. Cocaine-amphetamine-regulated transcript influences energy metabolism, anxiety and gastric emptying in mice. Hormone and Metabolic Research 2001; 33: 554-558.
    • (2001) Hormone and Metabolic Research , vol.33 , pp. 554-558
    • Asakawa, A.1    Inui, A.2    Yuzuriha, H.3
  • 84
    • 17844380766 scopus 로고    scopus 로고
    • Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei
    • Abbott CR, Rossi M, Wren AM et al. Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinology 2001; 142: 3457-3463.
    • (2001) Endocrinology , vol.142 , pp. 3457-3463
    • Abbott, C.R.1    Rossi, M.2    Wren, A.M.3
  • 85
    • 0033761530 scopus 로고    scopus 로고
    • Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice
    • Makimura H, Mizuno TM, Roberts J et al. Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice. Diabetes 2000; 49: 1917-1923.
    • (2000) Diabetes , vol.49 , pp. 1917-1923
    • Makimura, H.1    Mizuno, T.M.2    Roberts, J.3
  • 86
    • 0035479022 scopus 로고    scopus 로고
    • Knockout models resulting in the development of obesity
    • Butler AA & Cone RD. Knockout models resulting in the development of obesity. Trends in Genetics 2001; 17: S50-S54.
    • (2001) Trends in Genetics , vol.17
    • Butler, A.A.1    Cone, R.D.2
  • 87
    • 0024471489 scopus 로고
    • Opposite effects of centrally administered neuropeptide Y (NPY) on locomotor activity of spontaneously hypertensive (SH) and normal rats
    • Heilig M, Vecsei L & Widerlov E. Opposite effects of centrally administered neuropeptide Y (NPY) on locomotor activity of spontaneously hypertensive (SH) and normal rats. Acta Physiologica Scandinavica 1989; 137: 243-248.
    • (1989) Acta Physiologica Scandinavica , vol.137 , pp. 243-248
    • Heilig, M.1    Vecsei, L.2    Widerlov, E.3
  • 88
    • 0033913720 scopus 로고    scopus 로고
    • Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference
    • Kimmel HL, Gong W, Vechia SD et al. Intra-ventral tegmental area injection of rat cocaine and amphetamine-regulated transcript peptide 55-102 induces locomotor activity and promotes conditioned place preference. Journal of Pharmacology and Experimental Therapeutics 2000; 294: 784-792.
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.294 , pp. 784-792
    • Kimmel, H.L.1    Gong, W.2    Vechia, S.D.3
  • 89
    • 0025685421 scopus 로고
    • Hyperinsulinemia increases the amount of GLUT4 mRNA in white adipose tissue and decreases that of muscles: A clue for increased fat depot and insulin resistance
    • Cusin I, Terrettaz J, Rohner-Jeanrenaud F et al. Hyperinsulinemia increases the amount of GLUT4 mRNA in white adipose tissue and decreases that of muscles: A clue for increased fat depot and insulin resistance. Endocrinology 1990; 127: 3246-3248.
    • (1990) Endocrinology , vol.127 , pp. 3246-3248
    • Cusin, I.1    Terrettaz, J.2    Rohner-Jeanrenaud, F.3
  • 90
    • 0022980751 scopus 로고
    • Metabolic consequences of prolonged hyperinsulinemia in humans. Evidence for induction of insulin insensitivity
    • Marangou AG, Weber KM, Boston RC et al. Metabolic consequences of prolonged hyperinsulinemia in humans. Evidence for induction of insulin insensitivity. Diabetes 1986; 35: 1383-1389.
    • (1986) Diabetes , vol.35 , pp. 1383-1389
    • Marangou, A.G.1    Weber, K.M.2    Boston, R.C.3
  • 91
    • 0026601859 scopus 로고
    • Patients with insulinoma show insulin resistance in the absence of arterial hypertension
    • Pontiroli AE, Alberetto M & Pozza G. Patients with insulinoma show insulin resistance in the absence of arterial hypertension. Diabetologia 1992; 35: 294-295.
    • (1992) Diabetologia , vol.35 , pp. 294-295
    • Pontiroli, A.E.1    Alberetto, M.2    Pozza, G.3
  • 93
    • 0034093811 scopus 로고    scopus 로고
    • Diazoxide down-regulates leptin and lipid metabolizing enzymes in adipose tissue of Zucker rats
    • Standridge M, Alemzadeh R, Zemel M et al. Diazoxide down-regulates leptin and lipid metabolizing enzymes in adipose tissue of Zucker rats. FASEB Journal 2000; 14: 455-460.
    • (2000) FASEB Journal , vol.14 , pp. 455-460
    • Standridge, M.1    Alemzadeh, R.2    Zemel, M.3
  • 94
    • 0030831040 scopus 로고    scopus 로고
    • Chronic central neuropeptide Y infusion in normal rats - Status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia
    • Sainsbury A, Rohner-Jeanrenaud F, Cusin I et al. Chronic central neuropeptide Y infusion in normal rats - Status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia. Diabetologia 1997; 40: 1269-1277.
    • (1997) Diabetologia , vol.40 , pp. 1269-1277
    • Sainsbury, A.1    Rohner-Jeanrenaud, F.2    Cusin, I.3
  • 95
    • 0034527518 scopus 로고    scopus 로고
    • Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes
    • Raposinho PD, Castillo E, D'Alleves V et al. Chronic blockade of the melanocortin 4 receptor subtype leads to obesity independently of neuropeptide Y action, with no adverse effects on the gonadotropic and somatotropic axes. Endocrinology 2000; 141: 4419-4427.
    • (2000) Endocrinology , vol.141 , pp. 4419-4427
    • Raposinho, P.D.1    Castillo, E.2    D'Alleves, V.3
  • 96
    • 0028231062 scopus 로고
    • Obesity, diabetes and neoplasia in yellow A(vy)/- mice: Ectopic expression of the agouti gene
    • Yen TT, Gill AM, Frigeri LG et al. Obesity, diabetes and neoplasia in yellow A(vy)/- mice: Ectopic expression of the agouti gene. FASEB Journal 1994; 8: 479-488.
    • (1994) FASEB Journal , vol.8 , pp. 479-488
    • Yen, T.T.1    Gill, A.M.2    Frigeri, L.G.3
  • 97
    • 0030678119 scopus 로고    scopus 로고
    • Independent and additive effects of central POMC and leptin pathways on murine obesity
    • Boston BA, Blaydon KM, Varnerin J et al. Independent and additive effects of central POMC and leptin pathways on murine obesity. Science 1997; 278: 1641-1644.
    • (1997) Science , vol.278 , pp. 1641-1644
    • Boston, B.A.1    Blaydon, K.M.2    Varnerin, J.3
  • 98
    • 0026649567 scopus 로고
    • Effect of chronic stress and exogenous glucocorticoids on regional fat distribution and metabolism
    • Rebuffe-Scrive M, Walsh UA, McEwen B et al. Effect of chronic stress and exogenous glucocorticoids on regional fat distribution and metabolism. Physiology and Behaviour 1992; 52: 583-590.
    • (1992) Physiology and Behaviour , vol.52 , pp. 583-590
    • Rebuffe-Scrive, M.1    Walsh, U.A.2    McEwen, B.3
  • 99
    • 0027372655 scopus 로고
    • Feast and famine: Critical role of glucocorticoids with insulin in daily energy flow
    • Dallman MF, Strack AM, Akana SF et al. Feast and famine: Critical role of glucocorticoids with insulin in daily energy flow. Frontiers in Neuroendocrinology 1993; 14: 303-347.
    • (1993) Frontiers in Neuroendocrinology , vol.14 , pp. 303-347
    • Dallman, M.F.1    Strack, A.M.2    Akana, S.F.3
  • 100
    • 0026588548 scopus 로고
    • Intraventricular corticosterone increases the rate of body weight gain in underweight adrenalectomized rats
    • Green PK, Wilkinson CW & Woods SC. Intraventricular corticosterone increases the rate of body weight gain in underweight adrenalectomized rats. Endocrinology 1992; 130: 269-275.
    • (1992) Endocrinology , vol.130 , pp. 269-275
    • Green, P.K.1    Wilkinson, C.W.2    Woods, S.C.3
  • 101
    • 0033014744 scopus 로고    scopus 로고
    • Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat
    • Zakrzewska KE, Cusin I, Stricker-Krongrad A et al. Induction of obesity and hyperleptinemia by central glucocorticoid infusion in the rat. Diabetes 1999; 48: 365-370.
    • (1999) Diabetes , vol.48 , pp. 365-370
    • Zakrzewska, K.E.1    Cusin, I.2    Stricker-Krongrad, A.3
  • 103
    • 0035320914 scopus 로고    scopus 로고
    • Central but not peripheral glucocorticoid infusion in adrenalectomized male rats increases basal and substrate-induced insulinemia via a parasympathetic pathway
    • Sainsbury A, Wilks D & Cooney GJ. Central but not peripheral glucocorticoid infusion in adrenalectomized male rats increases basal and substrate-induced insulinemia via a parasympathetic pathway. Obesity Research 2001; 9: 274-281.
    • (2001) Obesity Research , vol.9 , pp. 274-281
    • Sainsbury, A.1    Wilks, D.2    Cooney, G.J.3
  • 104
    • 0001312506 scopus 로고
    • Neuropeptide Y actions on reproductive and endocrine functions
    • In Colmers WF & Wahlestedt C (eds); New Jersey: Humana Press Inc
    • McDonald JK & Koenig JI. Neuropeptide Y actions on reproductive and endocrine functions. In Colmers WF & Wahlestedt C (eds) The Biology of Neuropeptide Y and Related Peptides, pp 419-456. New Jersey: Humana Press Inc, 1993.
    • (1993) The Biology of Neuropeptide Y and Related Peptides , pp. 419-456
    • McDonald, J.K.1    Koenig, J.I.2


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