Leptin signaling, adiposity, and energy balance

Annals of the New York Academy of Sciences

Volumn 967, Issue , 2002, Pages 379-388

  Jéquier, Eric ^a,b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b Institut de Physiologie   (Switzerland)

Author keywords

Body weight; Energy expenditure; Food intake; Obesity; Starvation

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID; LEPTIN; LEPTIN RECEPTOR; MELANIN CONCENTRATING HORMONE; MESSENGER RNA; NEUROPEPTIDE Y; OREXIN;

BODY WEIGHT; CONFERENCE PAPER; ENERGY BALANCE; ENERGY EXPENDITURE; FOOD INTAKE; GENE EXPRESSION REGULATION; HORMONAL REGULATION; HUMAN; LIPID STORAGE; NEUROENDOCRINOLOGY; OBESITY; SIGNAL TRANSDUCTION; STARVATION; WEIGHT REDUCTION;

AGOUTI; RODENTIA;

EID: 0036293591     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04293.x     Document Type: Conference Paper

References (53)

1. Obesity and the regulation of energy balance
2. How not to approach the obesity problem
3. Comparison of dietary assessment methods in nutritional epidemiology: Weighed records v. 24 h recalls, food-frequency questionnaires, and estimated-diet records
4. Long-term measurements of energy expenditure in humans using a respiration chamber
5. Reduced rate of energy expenditure as a risk factor for body-weight gain
6. Development of beta 3-adrenoceptor agonists for the treatment of obesity and diabetes - An update
7. New evidence for a thermogenic defect in human obesity
8. Positional cloning of the mouse ob gene and its human homologue
9. Serum immunoreactive-leptin concentrations in normal-weight and obese humans
10. Transient increase in obese gene expression after food intake or insulin administration
11. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
12. Weight-reducing effects of the plasma protein encoded by the obese gene
13. Effects of the obese gene product on body weight regulation in ob/ob mice
14. Increased obese mRNA expression in omental fat cells from massively obese humans
15. Lipid second messengers
16. Cellular and molecular aspects of adipose tissue development
17. Mitotic forces control a cell-cycle checkpoint
18. Sexual dimorphism in plasma leptin concentration
19. Leptin concentrations, sex hormones, and cortisol in nondiabetic men
20. Relationship of serum leptin levels with body composition and sex steroid and insulin levels in men and women
21. Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP
22. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
23. Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
24. Severe early-onset obesity, adrenal insufficiency, and red hair pigmentation caused by POMC mutations in humans
25. Leptin enters the brain by a saturable system independent of insulin
26. Diet-induced obese mice develop peripheral, but not central, resistance to leptin
27. Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
28. Recombinant leptin for weight loss in obese and lean adults: A randomized, controlled, dose-escalation trial
29. Decreased cerebrospinal-fluid/serum leptin ratio in obesity: A possible mechanism for leptin resistance
30. Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
31. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
32. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice, but not db/db mice
33. SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985
34. Divergent roles of SHP-2 in ERK activation by leptin receptors
35. Abnormal splicing of the leptin receptor in diabetic mice
36. From lesions to leptin: Hypothalamic control of food intake and body weight
37. The hypothalamic leptin receptor in humans
38. Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice
39. Localization of binding sites in the central nervous system for leptin (OB protein) in normal, obese (ob/ob), and diabetic (db/db) C57BL/6J mice
40. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
41. Leptin directly alters lipid partitioning in skeletal muscle
42. Direct antidiabetic effect of leptin through triglyceride depletion of tissues
43. Leptin physiology: A second look
44. Diseases of liporegulation: New perspective on obesity and related disorders
45. Endocytosis of low-density lipoprotein by human pancreatic beta cells and uptake in lipid-storing vesicles, which increase with age
46. Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats
47. The "thrifty genotype" in 1998
48. The role of SOCS-3 in leptin signaling and leptin resistance
49. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
50. Responses of leptin to short-term fasting and refeeding in humans
51. Role of leptin in the neuro-endocrine response to fasting
52. Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus
53. Role of leptin in hypothalamic-pituitary function