메뉴 건너뛰기




Volumn 14, Issue 6, 2003, Pages 351-356

Endocrinological activities of ghrelin: New insights

Author keywords

Cortisol; Ghrelin; Growth hormone; Hypothalamus; Pituitary; Prolactin

Indexed keywords

GHRELIN; GLUCAGON; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HYDROCORTISONE; INSULIN; OCTREOTIDE; SOMATOSTATIN;

EID: 4344680499     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0953-6205(03)90000-8     Document Type: Review
Times cited : (8)

References (59)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999;402:656-60.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3
  • 2
    • 0034676324 scopus 로고    scopus 로고
    • Structure-function studies on the new growth hormone-releasing peptide, ghrelin: Minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a
    • Bednarek MA, Feighner SD, Pong SS et al. Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a. J Med Chem 2000;43:4370-6.
    • (2000) J Med Chem , vol.43 , pp. 4370-4376
    • Bednarek, M.A.1    Feighner, S.D.2    Pong, S.S.3
  • 3
    • 0036225018 scopus 로고    scopus 로고
    • Short ghrelin peptides neither displace ghrelin binding in vitro nor stimulate GH release in vivo
    • Torsello A, Ghe' C, Bresciani E et al. Short ghrelin peptides neither displace ghrelin binding in vitro nor stimulate GH release in vivo. Endocrinology 2002;143:1968-71.
    • (2002) Endocrinology , vol.143 , pp. 1968-1971
    • Torsello, A.1    Ghe, C.2    Bresciani, E.3
  • 4
    • 0036720568 scopus 로고    scopus 로고
    • Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats
    • Tamura H, Kamegai J, Shimizu T et al. Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats. Endocrinology 2002;143:3268-75.
    • (2002) Endocrinology , vol.143 , pp. 3268-3275
    • Tamura, H.1    Kamegai, J.2    Shimizu, T.3
  • 5
    • 0035085099 scopus 로고    scopus 로고
    • Presence of ghrelin in normal and adenomatous human pituitary
    • Korbonits M, Kojima M, Kangawa K, Grossman AB. Presence of ghrelin in normal and adenomatous human pituitary. Endocrine 2001;14:101-4.
    • (2001) Endocrine , vol.14 , pp. 101-104
    • Korbonits, M.1    Kojima, M.2    Kangawa, K.3    Grossman, A.B.4
  • 6
    • 0034824420 scopus 로고    scopus 로고
    • Regulation of Pit-1 expression by ghrelin and GHRP-6 through the GH secretagogue receptor
    • Garcia A, Alvarez CV, Smith RG, Dieguez C. Regulation of Pit-1 expression by ghrelin and GHRP-6 through the GH secretagogue receptor. Mol Endocrinol 2001;15:1484-95.
    • (2001) Mol Endocrinol , vol.15 , pp. 1484-1495
    • Garcia, A.1    Alvarez, C.V.2    Smith, R.G.3    Dieguez, C.4
  • 7
    • 0036263016 scopus 로고    scopus 로고
    • Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity
    • Shuto Y, Shibasaki T, Otagiri A et al. Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity. J Clin Invest 2002;109:1429-36.
    • (2002) J Clin Invest , vol.109 , pp. 1429-1436
    • Shuto, Y.1    Shibasaki, T.2    Otagiri, A.3
  • 8
    • 0034726741 scopus 로고    scopus 로고
    • Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats
    • Date Y, Murakami N, Kojima M et al. Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats. Biochem Biophys Res Commun 2000;28:477-80.
    • (2000) Biochem Biophys Res Commun , vol.28 , pp. 477-480
    • Date, Y.1    Murakami, N.2    Kojima, M.3
  • 9
    • 0033663608 scopus 로고    scopus 로고
    • Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats
    • Seoane LM, Tovar S, Baldelli R et al. Ghrelin elicits a marked stimulatory effect on GH secretion in freely-moving rats. Eur J Endocrinol 2000;143:R7-9.
    • (2000) Eur J Endocrinol , vol.143
    • Seoane, L.M.1    Tovar, S.2    Baldelli, R.3
  • 10
    • 0033805978 scopus 로고    scopus 로고
    • Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans
    • Arvat E, Di Vito L, Broglio F et al. Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans. J Endocrinol Invest 2000;23:493-5.
    • (2000) J Endocrinol Invest , vol.23 , pp. 493-495
    • Arvat, E.1    Di Vito, L.2    Broglio, F.3
  • 11
    • 0036218881 scopus 로고    scopus 로고
    • Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats
    • Tolle V, Bassant MH, Zizzari P et al. Ultradian rhythmicity of ghrelin secretion in relation with GH, feeding behavior, and sleep-wake patterns in rats. Endocrinology 2002;143:1353-61.
    • (2002) Endocrinology , vol.143 , pp. 1353-1361
    • Tolle, V.1    Bassant, M.H.2    Zizzari, P.3
  • 12
    • 0037243646 scopus 로고    scopus 로고
    • Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women
    • Tolle V, Kadem M, Bluet-Pajot MT et al. Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women. J Clin Endocrinol Metab 2003;88:109-16.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 109-116
    • Tolle, V.1    Kadem, M.2    Bluet-Pajot, M.T.3
  • 13
    • 0037372024 scopus 로고    scopus 로고
    • Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion
    • Tannenbaum GS, Epelbaum J, Bowers CY. Interrelationship between the novel peptide ghrelin and somatostatin/growth hormone-releasing hormone in regulation of pulsatile growth hormone secretion. Endocrinology 2003;144:967-74.
    • (2003) Endocrinology , vol.144 , pp. 967-974
    • Tannenbaum, G.S.1    Epelbaum, J.2    Bowers, C.Y.3
  • 14
    • 0037220691 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations are not regulated by glucose or insulin: A double-blind, placebo-controlled crossover clamp study
    • Schaller G, Schmidt A, Pleiner J et al. Plasma ghrelin concentrations are not regulated by glucose or insulin: a double-blind, placebo-controlled crossover clamp study. Diabetes 2003;52:16-20.
    • (2003) Diabetes , vol.52 , pp. 16-20
    • Schaller, G.1    Schmidt, A.2    Pleiner, J.3
  • 15
    • 0036399151 scopus 로고    scopus 로고
    • Ghrelin immunoreactivity in human plasma is suppressed by somatostatin
    • Norrelund H, Hansen TK, Orskov H et al. Ghrelin immunoreactivity in human plasma is suppressed by somatostatin. Clin Endocrinol 2002;57:539-46.
    • (2002) Clin Endocrinol , vol.57 , pp. 539-546
    • Norrelund, H.1    Hansen, T.K.2    Orskov, H.3
  • 16
    • 0036360192 scopus 로고    scopus 로고
    • Effects of glucose, free fatty acids or arginine load on the GH-releasing activity of ghrelin in humans
    • Broglio F, Benso A, Gottero C et al. Effects of glucose, free fatty acids or arginine load on the GH-releasing activity of ghrelin in humans. Clin Endocrinol 2002;57:265-71.
    • (2002) Clin Endocrinol , vol.57 , pp. 265-271
    • Broglio, F.1    Benso, A.2    Gottero, C.3
  • 17
    • 0036268616 scopus 로고    scopus 로고
    • The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans
    • Di Vito L, Broglio F, Benso A et al. The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans. Clin Endocrinol 2002;56:643-8.
    • (2002) Clin Endocrinol , vol.56 , pp. 643-648
    • Di Vito, L.1    Broglio, F.2    Benso, A.3
  • 18
    • 18644363784 scopus 로고    scopus 로고
    • Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans
    • Broglio F, Koetsveld PvP, Benso A et al. Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans. J Clin Endocrinol Metab 2002;87:4829-32.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4829-4832
    • Broglio, F.1    Koetsveld, Pv.P.2    Benso, A.3
  • 19
    • 0037320674 scopus 로고    scopus 로고
    • Agouti-related peptide, neuropeptide y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus
    • Seoane LM, Lopez M, Tovar S et al. Agouti-related peptide, neuropeptide y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus. Endocrinology 2003;144:544-51.
    • (2003) Endocrinology , vol.144 , pp. 544-551
    • Seoane, L.M.1    Lopez, M.2    Tovar, S.3
  • 20
    • 0035117145 scopus 로고    scopus 로고
    • Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland
    • Deghenghi R, Papotti M, Ghigo E, Muccioli G. Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland. J Endocrinol Invest 2001;24:RC1-3.
    • (2001) J Endocrinol Invest , vol.24
    • Deghenghi, R.1    Papotti, M.2    Ghigo, E.3    Muccioli, G.4
  • 21
    • 0035085142 scopus 로고    scopus 로고
    • Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin
    • Tannenbaum GS, Bowers CY. Interactions of growth hormone secretagogues and growth hormone-releasing hormone/somatostatin. Endocrine 2001;14:21-7.
    • (2001) Endocrine , vol.14 , pp. 21-27
    • Tannenbaum, G.S.1    Bowers, C.Y.2
  • 22
    • 0034878898 scopus 로고    scopus 로고
    • Regulation of the ghrelin gene: Growth hormone-releasing hormone upregulates ghrelin mRNA in the pituitary
    • Kamegai J, Tamura H, Shimizu T et al. Regulation of the ghrelin gene: growth hormone-releasing hormone upregulates ghrelin mRNA in the pituitary. Endocrinology 2001;142:4154-7.
    • (2001) Endocrinology , vol.142 , pp. 4154-4157
    • Kamegai, J.1    Tamura, H.2    Shimizu, T.3
  • 23
    • 17944364819 scopus 로고    scopus 로고
    • A low dose of ghrelin stimulates growth hormone (GH) release synergistically with GH-releasing hormone in humans
    • Hataya Y, Akamizu T, Takaya K et al. A low dose of ghrelin stimulates growth hormone (GH) release synergistically with GH-releasing hormone in humans. J Clin Endocrinol Metab 2001;86:4552.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4552
    • Hataya, Y.1    Akamizu, T.2    Takaya, K.3
  • 24
    • 0036141444 scopus 로고    scopus 로고
    • Regulational effect of ghrelin on growth hormone secretion from perifused rat anterior pituitary cells
    • Yamazaki M, Nakamura K, Kobayashi H et al. Regulational effect of ghrelin on growth hormone secretion from perifused rat anterior pituitary cells. J Neuroendocrinol 2002;14:156-62.
    • (2002) J Neuroendocrinol , vol.14 , pp. 156-162
    • Yamazaki, M.1    Nakamura, K.2    Kobayashi, H.3
  • 25
    • 0036442864 scopus 로고    scopus 로고
    • The hypothalamic mechanisms of the hypophysiotropic action of ghrelin
    • Wren AM, Small CJ, Fribbens CV et al. The hypothalamic mechanisms of the hypophysiotropic action of ghrelin. Neuroendocrinology 2002;76:316-24.
    • (2002) Neuroendocrinology , vol.76 , pp. 316-324
    • Wren, A.M.1    Small, C.J.2    Fribbens, C.V.3
  • 26
    • 0036224988 scopus 로고    scopus 로고
    • Role of ghrelin in the regulation of vasopressin release in conscious rats
    • Ishizaki S, Murase T, Sugimura Y et al. Role of ghrelin in the regulation of vasopressin release in conscious rats. Endocrinology 2002;143:589-1593.
    • (2002) Endocrinology , vol.143 , pp. 589-1593
    • Ishizaki, S.1    Murase, T.2    Sugimura, Y.3
  • 27
    • 0035834586 scopus 로고    scopus 로고
    • Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats
    • Furuta M, Funabashi T, Kimura F. Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats. Biochem Biophys Res Commun 2001;288:780-5.
    • (2001) Biochem Biophys Res Commun , vol.288 , pp. 780-785
    • Furuta, M.1    Funabashi, T.2    Kimura, F.3
  • 28
    • 0040184557 scopus 로고    scopus 로고
    • Ghrelin strongly stimulates growth hormone release in humans
    • Takaya K, Ariyasu H, Kanamoto N et al. Ghrelin strongly stimulates growth hormone release in humans. J Clin Endocrinol Metab 2000;85:4908-11.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4908-4911
    • Takaya, K.1    Ariyasu, H.2    Kanamoto, N.3
  • 30
    • 17744374270 scopus 로고    scopus 로고
    • Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: Comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone
    • Arvat E, Maccario M, Di Vito L et al. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone. J Clin Endocrinol Metab 2001;86:1169-74.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1169-1174
    • Arvat, E.1    Maccario, M.2    Di Vito, L.3
  • 31
    • 0037232370 scopus 로고    scopus 로고
    • Acetylcholine does not play a major role in mediating the endocrine responses to ghrelin, a natural ligand of the GH secretagogue receptor, in humans
    • Oxf
    • Broglio F, Gottero C, Benso A et al. Acetylcholine does not play a major role in mediating the endocrine responses to ghrelin, a natural ligand of the GH secretagogue receptor, in humans. Clin Endocrinol (Oxf) 2003;58:92-8.
    • (2003) Clin Endocrinol , vol.58 , pp. 92-98
    • Broglio, F.1    Gottero, C.2    Benso, A.3
  • 32
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren AM, Small CJ, Ward HL et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2000;141:4325-8.
    • (2000) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3
  • 33
    • 0141923119 scopus 로고    scopus 로고
    • Cardiovascular and hormonal effects of subcutaneous administration of Ghrelin, a novel growth hormone-releasing peptide, in healthy humans
    • Lond e-published ahead of print
    • Enomoto M, Nagaya N, Uematsu M, et al. Cardiovascular and hormonal effects of subcutaneous administration of Ghrelin, a novel growth hormone-releasing peptide, in healthy humans. Clin Sci (Lond) 2003;29 [e-published ahead of print].
    • (2003) Clin Sci , vol.29
    • Enomoto, M.1    Nagaya, N.2    Uematsu, M.3
  • 34
    • 18244390529 scopus 로고    scopus 로고
    • Novel expression and functional role of ghrelin in rat testis
    • Tena-Sempere M, Barreiro ML, Gonzalez LC et al. Novel expression and functional role of ghrelin in rat testis. Endocrinology 2002;143:717-25.
    • (2002) Endocrinology , vol.143 , pp. 717-725
    • Tena-Sempere, M.1    Barreiro, M.L.2    Gonzalez, L.C.3
  • 35
    • 0034986336 scopus 로고    scopus 로고
    • Gender and gonadal influences on ghrelin mRNA levels in rat stomach
    • Gualillo O, Caminos JE, Kojima M et al. Gender and gonadal influences on ghrelin mRNA levels in rat stomach. Eur J Endocrinol 2001;144:687-90.
    • (2001) Eur J Endocrinol , vol.144 , pp. 687-690
    • Gualillo, O.1    Caminos, J.E.2    Kojima, M.3
  • 36
    • 0037329049 scopus 로고    scopus 로고
    • Immunolocalization of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in the cyclic human ovary
    • Gaytan F, Barreiro ML, Chopin LK et al. Immunolocalization of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in the cyclic human ovary. J Clin Endocrinol Metab 2003;88:879-87.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 879-887
    • Gaytan, F.1    Barreiro, M.L.2    Chopin, L.K.3
  • 37
    • 0036925201 scopus 로고    scopus 로고
    • Plasma ghrelin, obesity, and the polycystic ovary syndrome: Correlation with insulin resistance and androgen levels
    • Pagotto U, Gambineri A, Vicennati V et al. Plasma ghrelin, obesity, and the polycystic ovary syndrome: correlation with insulin resistance and androgen levels. J Clin Endocrinol Metab 2002;87:5625-9.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5625-5629
    • Pagotto, U.1    Gambineri, A.2    Vicennati, V.3
  • 38
    • 0036855443 scopus 로고    scopus 로고
    • Expression and homologous regulation of GH secretagogue receptor mRNA in rat adrenal gland
    • Barreiro ML, Pinilla L, Aguilar E, Tena-Sempere M. Expression and homologous regulation of GH secretagogue receptor mRNA in rat adrenal gland. Eur J Endocrinol 2002;147:677-88.
    • (2002) Eur J Endocrinol , vol.147 , pp. 677-688
    • Barreiro, M.L.1    Pinilla, L.2    Aguilar, E.3    Tena-Sempere, M.4
  • 39
    • 0037331656 scopus 로고    scopus 로고
    • Ghrelin in fetal thyroid and follicular tumors and cell lines: Expression and effects on tumor growth
    • Volante M, Allia E, Fulcheri E et al. Ghrelin in fetal thyroid and follicular tumors and cell lines: expression and effects on tumor growth. Am J Pathol 2003;162:645-54.
    • (2003) Am J Pathol , vol.162 , pp. 645-654
    • Volante, M.1    Allia, E.2    Fulcheri, E.3
  • 40
    • 17944364737 scopus 로고    scopus 로고
    • Substantial production of ghrelin by a human medullary thyroid carcinoma cell line
    • Kanamoto N, Akamizu T, Hosoda H et al. Substantial production of ghrelin by a human medullary thyroid carcinoma cell line. J Clin Endocrinol Metab 2001;86:4984-90.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4984-4990
    • Kanamoto, N.1    Akamizu, T.2    Hosoda, H.3
  • 42
  • 44
    • 0036789176 scopus 로고    scopus 로고
    • Ghrelin is not necessary for adequate hormonal counterregulation of insulin-induced hypoglycemia
    • Lucidi P, Murdolo G, Di Loreto C et al. Ghrelin is not necessary for adequate hormonal counterregulation of insulin-induced hypoglycemia. Diabetes 2002;51:2911-4.
    • (2002) Diabetes , vol.51 , pp. 2911-2914
    • Lucidi, P.1    Murdolo, G.2    Di Loreto, C.3
  • 45
    • 0036064740 scopus 로고    scopus 로고
    • Endocrine responses to ghrelin in adult patients with isolated childhood-onset growth hormone deficiency
    • Aimaretti G, Baffoni C, Broglio F et al. Endocrine responses to ghrelin in adult patients with isolated childhood-onset growth hormone deficiency. Clin Endocrinol 2002;56:765-71.
    • (2002) Clin Endocrinol , vol.56 , pp. 765-771
    • Aimaretti, G.1    Baffoni, C.2    Broglio, F.3
  • 46
    • 0035214675 scopus 로고    scopus 로고
    • Systemic ghrelin levels in subjects with growth hormone deficiency are not modified by one year of growth hormone replacement therapy
    • Janssen JA, van der Toorn FM, Hofland LJ et al. Systemic ghrelin levels in subjects with growth hormone deficiency are not modified by one year of growth hormone replacement therapy. Eur J Endocrinol 2001;145:711-6.
    • (2001) Eur J Endocrinol , vol.145 , pp. 711-716
    • Janssen, J.A.1    Van Der Toorn, F.M.2    Hofland, L.J.3
  • 47
    • 0036316624 scopus 로고    scopus 로고
    • Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients
    • Dall R, Kanaley J, Hansen TK et al. Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients. Eur J Endocrinol 2002;147:65-70.
    • (2002) Eur J Endocrinol , vol.147 , pp. 65-70
    • Dall, R.1    Kanaley, J.2    Hansen, T.K.3
  • 48
    • 0036141195 scopus 로고    scopus 로고
    • Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: Enteric distribution, ontogeny, influence of endocrine, and dietary manipulations
    • Lee HM, Wang G, Englander EW, Kojima M, Greeley Jr. GH. Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology 2002;143:85-190.
    • (2002) Endocrinology , vol.143 , pp. 85-190
    • Lee, H.M.1    Wang, G.2    Englander, E.W.3    Kojima, M.4    Greeley Jr., G.H.5
  • 49
    • 0036777687 scopus 로고    scopus 로고
    • Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats
    • Tschöp M, Flora DB, Mayer JP, Heiman ML. Hypophysectomy prevents ghrelin-induced adiposity and increases gastric ghrelin secretion in rats. Obes Res 2002;10:991-9.
    • (2002) Obes Res , vol.10 , pp. 991-999
    • Tschöp, M.1    Flora, D.B.2    Mayer, J.P.3    Heiman, M.L.4
  • 50
    • 0036061558 scopus 로고    scopus 로고
    • Elevated plasma ghrelin levels in Prader Willi syndrome
    • Cummings DE, Clement K, Purnell JQ et al. Elevated plasma ghrelin levels in Prader Willi syndrome. Nat Med 2002;8:643-4.
    • (2002) Nat Med , vol.8 , pp. 643-644
    • Cummings, D.E.1    Clement, K.2    Purnell, J.Q.3
  • 51
    • 0036928761 scopus 로고    scopus 로고
    • High circulating ghrelin: A potential cause for hyperphagia and obesity in prader-willi syndrome
    • DelParigi A, Tschöp M, Heiman ML et al. High circulating ghrelin: a potential cause for hyperphagia and obesity in prader-willi syndrome. J Clin Endocrinol Metab 2002;87:5461-4.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5461-5464
    • Delparigi, A.1    Tschöp, M.2    Heiman, M.L.3
  • 52
    • 0036679260 scopus 로고    scopus 로고
    • Central ghrelin production does not substantially contribute to systemic ghrelin concentrations: A study in two subjects with active acromegaly
    • van der Toorn FM, Janssen JA, de Herder WW et al. Central ghrelin production does not substantially contribute to systemic ghrelin concentrations: a study in two subjects with active acromegaly. Eur J Endocrinol 2002;147:195-9.
    • (2002) Eur J Endocrinol , vol.147 , pp. 195-199
    • Van Der Toorn, F.M.1    Janssen, J.A.2    De Herder, W.W.3
  • 53
    • 0036677654 scopus 로고    scopus 로고
    • Circulating ghrelin levels in basal conditions and during glucose tolerance test in acromegalic patients
    • Cappiello V, Ronchi C, Morpurgo PS et al. Circulating ghrelin levels in basal conditions and during glucose tolerance test in acromegalic patients. Eur J Endocrinol 2002;147:189-94.
    • (2002) Eur J Endocrinol , vol.147 , pp. 189-194
    • Cappiello, V.1    Ronchi, C.2    Morpurgo, P.S.3
  • 55
    • 0036107852 scopus 로고    scopus 로고
    • Neuroendocrine and metabolic determinants of the adaptation of GH/IGF-I axis to obesity
    • Paris
    • Maccario M, Tassone F, Grottoli S et al. Neuroendocrine and metabolic determinants of the adaptation of GH/IGF-I axis to obesity. Ann Endocrinol (Paris) 2002;63:140-4.
    • (2002) Ann Endocrinol , vol.63 , pp. 140-144
    • Maccario, M.1    Tassone, F.2    Grottoli, S.3
  • 56
    • 0036102978 scopus 로고    scopus 로고
    • Vasodilatory effect of ghrelin, an endogenous peptide from the stomach
    • Okumura H, Nagaya N, Enomoto M et al. Vasodilatory effect of ghrelin, an endogenous peptide from the stomach. J Cardiovasc Pharmacol 2002;39:779-83.
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 779-783
    • Okumura, H.1    Nagaya, N.2    Enomoto, M.3
  • 57
    • 0036247188 scopus 로고    scopus 로고
    • Circulating ghrelin levels as function of gender, pubertal status and adiposity in childhood
    • Bellone S, Rapa A, Vivenza D et al. Circulating ghrelin levels as function of gender, pubertal status and adiposity in childhood. J Endocrinol Invest 2002;25:RC13-5.
    • (2002) J Endocrinol Invest , vol.25
    • Bellone, S.1    Rapa, A.2    Vivenza, D.3
  • 58
    • 0037930163 scopus 로고    scopus 로고
    • Ghrelin and the hyposomatotropism of obesity
    • Lindeman JH, Pijl H, Van Dielen FM et al. Ghrelin and the hyposomatotropism of obesity. Obes Res 2002;10:1161-6.
    • (2002) Obes Res , vol.10 , pp. 1161-1166
    • Lindeman, J.H.1    Pijl, H.2    Van Dielen, F.M.3
  • 59
    • 0036802266 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations in elderly subjects: Comparison with anorexic and obese patients
    • Rigamonti AE, Pincelli AI, Corra B et al. Plasma ghrelin concentrations in elderly subjects: comparison with anorexic and obese patients. J Endocrinol 2002;175:R1-5.
    • (2002) J Endocrinol , vol.175
    • Rigamonti, A.E.1    Pincelli, A.I.2    Corra, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.