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Volumn 49, Issue 3, 2008, Pages 499-509

Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology

Author keywords

Cancer; Cutaneous; Differentiation; Inflammation; Permeability barrier; Proliferation; Skin; Stratum corneum; Transcription factor

Indexed keywords

3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ABC TRANSPORTER A1; CHOLESTEROL DERIVATIVE; CHOLESTEROL SULFATE; CIGLITAZONE; CYCLOHEXIMIDE; ETRETIN; FILAGGRIN; GW 1514; INVOLUCRIN; LIVER X RECEPTOR; LIVER X RECEPTOR AGONIST; LORICRIN; OXYSTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PIRINIXIC ACID; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; ROSIGLITAZONE; SKIN LIPID; THIOACETIC ACID; TROGLITAZONE; UNCLASSIFIED DRUG; CELL RECEPTOR; DNA BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

EID: 42949178186     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.R800001-JLR200     Document Type: Review
Times cited : (169)

References (119)
  • 2
    • 0029887202 scopus 로고    scopus 로고
    • Population-based epidemiologic study of psoriasis with emphasis on quality of life assessment
    • Koo, J. 1996. Population-based epidemiologic study of psoriasis with emphasis on quality of life assessment. Dermatol. Clin. 14: 485-496.
    • (1996) Dermatol. Clin , vol.14 , pp. 485-496
    • Koo, J.1
  • 3
    • 3042593698 scopus 로고    scopus 로고
    • Epidemiology of psoriasis
    • Naldi, L. 2004. Epidemiology of psoriasis. Curr. Drug Targets. 3: 121-128.
    • (2004) Curr. Drug Targets , vol.3 , pp. 121-128
    • Naldi, L.1
  • 4
    • 0037431756 scopus 로고    scopus 로고
    • Atopic dermatitis
    • Leung, D. Y., and T. Bieber. 2003. Atopic dermatitis. Lancet. 361: 151-160.
    • (2003) Lancet , vol.361 , pp. 151-160
    • Leung, D.Y.1    Bieber, T.2
  • 8
    • 12344282955 scopus 로고    scopus 로고
    • Treatment of active psoriatic arthritis with the PPARgamma ligand pioglitazone: An open-label pilot study
    • Bongartz, T., B. Coras, T. Vogt, J. Scholmerich, and U. Muller-Ladner. 2005. Treatment of active psoriatic arthritis with the PPARgamma ligand pioglitazone: an open-label pilot study. Rheumatology (Oxford). 44: 126-129.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 126-129
    • Bongartz, T.1    Coras, B.2    Vogt, T.3    Scholmerich, J.4    Muller-Ladner, U.5
  • 9
    • 0034030527 scopus 로고    scopus 로고
    • Troglitazone improves psoriasis and normalizes models of proliferative skin disease: Ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation
    • Ellis, C. N., J. Varani, G. J. Fisher, M. E. Zeigler, H. A. Pershadsingh, S. C. Benson, Y. Chi, and T. W. Kurtz. 2000. Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation. Arch. Dermatol. 136: 609-616.
    • (2000) Arch. Dermatol , vol.136 , pp. 609-616
    • Ellis, C.N.1    Varani, J.2    Fisher, G.J.3    Zeigler, M.E.4    Pershadsingh, H.A.5    Benson, S.C.6    Chi, Y.7    Kurtz, T.W.8
  • 10
    • 13244286538 scopus 로고    scopus 로고
    • Pioglitazone: A promising therapy for psoriasis
    • Robertshaw, H., and P. S. Friedmann. 2005. Pioglitazone: a promising therapy for psoriasis. Br. J. Dermatol. 152: 189-191.
    • (2005) Br. J. Dermatol , vol.152 , pp. 189-191
    • Robertshaw, H.1    Friedmann, P.S.2
  • 12
    • 33750135442 scopus 로고    scopus 로고
    • Thiazolidinediones: Potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease
    • Varani, J., N. Bhagavathula, C. N. Ellis, and H. A. Pershadsingh. 2006. Thiazolidinediones: potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease. Expert Opin. Investig. Drugs. 15: 1453-1468.
    • (2006) Expert Opin. Investig. Drugs , vol.15 , pp. 1453-1468
    • Varani, J.1    Bhagavathula, N.2    Ellis, C.N.3    Pershadsingh, H.A.4
  • 15
    • 0036241593 scopus 로고    scopus 로고
    • The epidemiology of skin cancer
    • Diepgen, T. L., and V. Mahler. 2002. The epidemiology of skin cancer. Br. J. Dermatol. 146 (Suppl. 61): 1-6.
    • (2002) Br. J. Dermatol , vol.146 , Issue.SUPPL. 61 , pp. 1-6
    • Diepgen, T.L.1    Mahler, V.2
  • 16
    • 33748802515 scopus 로고    scopus 로고
    • Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis
    • Icre, G., W. Wahli, and L. Michalik. 2006. Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis. J. Invest. Dermatol. 11: 30-35.
    • (2006) J. Invest. Dermatol , vol.11 , pp. 30-35
    • Icre, G.1    Wahli, W.2    Michalik, L.3
  • 17
    • 34547602370 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease
    • Michalik, L., and W. Wahli. 2007. Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease. Biochim. Biophys. Acta. 1771: 991-998.
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 991-998
    • Michalik, L.1    Wahli, W.2
  • 18
    • 61849169690 scopus 로고    scopus 로고
    • Sebaceous gland lipids: Friend or foe?
    • In press
    • Smith, K. R., and D. M. Thiboutot. 2007. Sebaceous gland lipids: friend or foe? J. Lipid Res. 48: In press.
    • (2007) J. Lipid Res , vol.48
    • Smith, K.R.1    Thiboutot, D.M.2
  • 19
    • 33747154772 scopus 로고    scopus 로고
    • Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
    • Bookout, A. L., Y. Jeong, M. Downes, R. T. Yu, R. M. Evans, and D. J. Mangelsdorf. 2006. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell. 126: 789-799.
    • (2006) Cell , vol.126 , pp. 789-799
    • Bookout, A.L.1    Jeong, Y.2    Downes, M.3    Yu, R.T.4    Evans, R.M.5    Mangelsdorf, D.J.6
  • 20
    • 1842733168 scopus 로고    scopus 로고
    • Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma
    • Ghosh, A. K., S. Bhattacharyya, G. Lakos, S. J. Chen, Y. Mori, and J. Varga. 2004. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma. Arthritis Rheum. 50: 1305-1318.
    • (2004) Arthritis Rheum , vol.50 , pp. 1305-1318
    • Ghosh, A.K.1    Bhattacharyya, S.2    Lakos, G.3    Chen, S.J.4    Mori, Y.5    Varga, J.6
  • 22
    • 30744436829 scopus 로고    scopus 로고
    • Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands
    • Alestas, T., R. Ganceviciene, S. Fimmel, K. Muller-Decker, and C. C. Zouboulis. 2006. Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands. J. Mol. Med. 84: 75-87.
    • (2006) J. Mol. Med , vol.84 , pp. 75-87
    • Alestas, T.1    Ganceviciene, R.2    Fimmel, S.3    Muller-Decker, K.4    Zouboulis, C.C.5
  • 23
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant, O., F. Foufelle, C. Scotto, M. Dauca, and W. Wahli. 1996. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology. 137: 354-366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 24
    • 8344287013 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro
    • Downie, M. M., D. A. Sanders, L. M. Maier, D. M. Stock, and T. Kealey. 2004. Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro. Br. J. Dermatol. 151: 766-775.
    • (2004) Br. J. Dermatol , vol.151 , pp. 766-775
    • Downie, M.M.1    Sanders, D.A.2    Maier, L.M.3    Stock, D.M.4    Kealey, T.5
  • 25
    • 0035204352 scopus 로고    scopus 로고
    • Limited cooperation between peroxisome proliferator-activated receptors and retinoid X receptor agonists in sebocyte growth and development
    • Kim, M. J., D. Deplewski, N. Ciletti, S. Michel, U. Reichert, and R. L. Rosenfield. 2001. Limited cooperation between peroxisome proliferator-activated receptors and retinoid X receptor agonists in sebocyte growth and development. Mol. Genet. Metab. 74: 362-369.
    • (2001) Mol. Genet. Metab , vol.74 , pp. 362-369
    • Kim, M.J.1    Deplewski, D.2    Ciletti, N.3    Michel, S.4    Reichert, U.5    Rosenfield, R.L.6
  • 26
    • 34548484120 scopus 로고    scopus 로고
    • Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit
    • Russell, L. E., W. J. Harrison, A. W. Bahta, C. C. Zouboulis, J. M. Burrin, and M. P. Philpott. 2007. Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit. Exp. Dermatol. 16: 844-852.
    • (2007) Exp. Dermatol , vol.16 , pp. 844-852
    • Russell, L.E.1    Harrison, W.J.2    Bahta, A.W.3    Zouboulis, C.C.4    Burrin, J.M.5    Philpott, M.P.6
  • 27
    • 0034502453 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator activated receptors (PPARs) in human hair follicles and PPAR alpha involvement in hair growth
    • Billoni, N., B. Buan, B. Gautier, C. Collin, O. Gaillard, Y. F. Mahe, and B. A. Bernhard. 2000. Expression of peroxisome proliferator activated receptors (PPARs) in human hair follicles and PPAR alpha involvement in hair growth. Acta Derm. Venereol. 80: 329-334.
    • (2000) Acta Derm. Venereol , vol.80 , pp. 329-334
    • Billoni, N.1    Buan, B.2    Gautier, B.3    Collin, C.4    Gaillard, O.5    Mahe, Y.F.6    Bernhard, B.A.7
  • 28
    • 33749065765 scopus 로고    scopus 로고
    • Tcf3 governs stem cell features and represses cell fate determination in skin
    • Nguyen, H., M. Rendl, and E. Fuchs. 2006. Tcf3 governs stem cell features and represses cell fate determination in skin. Cell. 127: 171-183.
    • (2006) Cell , vol.127 , pp. 171-183
    • Nguyen, H.1    Rendl, M.2    Fuchs, E.3
  • 29
    • 0031788318 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development
    • Braissant, O., and W. Wahli. 1998. Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development. Endocrinology. 139: 2748-2754.
    • (1998) Endocrinology , vol.139 , pp. 2748-2754
    • Braissant, O.1    Wahli, W.2
  • 31
    • 0033601824 scopus 로고    scopus 로고
    • Correlation between expression of peroxisome proliferator-activated receptor beta and squamous differentiation in epidermal and tracheobronchial epithelial cells
    • Matsuura, H., H. Adachi, R. C. Smart, X. Xu, J. Arata, and A. M. Jetten. 1999. Correlation between expression of peroxisome proliferator-activated receptor beta and squamous differentiation in epidermal and tracheobronchial epithelial cells. Mol. Cell. Endocrinol. 147: 85-92.
    • (1999) Mol. Cell. Endocrinol , vol.147 , pp. 85-92
    • Matsuura, H.1    Adachi, H.2    Smart, R.C.3    Xu, X.4    Arata, J.5    Jetten, A.M.6
  • 32
    • 0032448111 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptor subtypes during the differentiation of human keratinocytes
    • Rivier, M., I. Safonova, P. Lebrun, C. E. Griffiths, G. Ailhaud, and S. Michel. 1998. Differential expression of peroxisome proliferator-activated receptor subtypes during the differentiation of human keratinocytes. J. Invest. Dermatol. 111: 1116-1121.
    • (1998) J. Invest. Dermatol , vol.111 , pp. 1116-1121
    • Rivier, M.1    Safonova, I.2    Lebrun, P.3    Griffiths, C.E.4    Ailhaud, G.5    Michel, S.6
  • 36
    • 0038221307 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: Consequences for the immune response
    • Angeli, V., H. Hammad, B. Staels, M. Capron, B. N. Lambrecht, and F. Trottein. 2003. Peroxisome proliferator-activated receptor gamma inhibits the migration of dendritic cells: consequences for the immune response. J. Immunol. 170: 5295-5301.
    • (2003) J. Immunol , vol.170 , pp. 5295-5301
    • Angeli, V.1    Hammad, H.2    Staels, B.3    Capron, M.4    Lambrecht, B.N.5    Trottein, F.6
  • 38
    • 1842558965 scopus 로고    scopus 로고
    • Expression and function of peroxisome proliferator-activated receptors in human melanocytes
    • Kang, H. Y., E. Chung, M. Lee, Y. Cho, and W. H. Kang. 2004. Expression and function of peroxisome proliferator-activated receptors in human melanocytes. Br. J. Dermatol. 150: 462-468.
    • (2004) Br. J. Dermatol , vol.150 , pp. 462-468
    • Kang, H.Y.1    Chung, E.2    Lee, M.3    Cho, Y.4    Kang, W.H.5
  • 39
    • 0034717067 scopus 로고    scopus 로고
    • The acute phase response is associated with retinoid X receptor repression in rodent liver
    • Beigneux, A. P., A. H. Moser, J. K. Shigenaga, C. Grunfeld, and K. R. Feingold. 2000. The acute phase response is associated with retinoid X receptor repression in rodent liver. J. Biol. Chem. 275: 16390-16399.
    • (2000) J. Biol. Chem , vol.275 , pp. 16390-16399
    • Beigneux, A.P.1    Moser, A.H.2    Shigenaga, J.K.3    Grunfeld, C.4    Feingold, K.R.5
  • 40
    • 0942287345 scopus 로고    scopus 로고
    • Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response
    • Feingold, K., M. S. Kim, J. Shigenaga, A. Moser, and C. Grunfeld. 2004. Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response. Am. J. Physiol. 286: E201-E207.
    • (2004) Am. J. Physiol , vol.286
    • Feingold, K.1    Kim, M.S.2    Shigenaga, J.3    Moser, A.4    Grunfeld, C.5
  • 41
    • 33845586654 scopus 로고    scopus 로고
    • Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response
    • Lu, B., A. H. Moser, J. K. Shigenaga, K. R. Feingold, and C. Grunfeld. 2006. Type II nuclear hormone receptors, coactivator, and target gene repression in adipose tissue in the acute-phase response. J. Lipid Res. 47: 2179-2190.
    • (2006) J. Lipid Res , vol.47 , pp. 2179-2190
    • Lu, B.1    Moser, A.H.2    Shigenaga, J.K.3    Feingold, K.R.4    Grunfeld, C.5
  • 46
    • 11244328917 scopus 로고    scopus 로고
    • The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide
    • Lo Verme, J., J. Fu, G. Astarita, G. La Rana, R. Russo, A. Calignano, andD. Piomelli. 2005. The nuclear receptor peroxisome proliferator-activated receptor-alpha mediates the anti-inflammatory actions of palmitoylethanolamide. Mol. Pharmacol. 67: 15-19.
    • (2005) Mol. Pharmacol , vol.67 , pp. 15-19
    • Lo Verme, J.J.1    Fu2    Astarita, G.3    La Rana, G.4    Russo, R.5    Calignano, A.6    andD7    Piomelli8
  • 50
    • 33646181467 scopus 로고    scopus 로고
    • Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta)
    • Kim, D. J., K. S. Prabhu, F. J. Gonzalez, and J. M. Peters. 2006. Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). Carcinogenesis. 27: 1105-1112.
    • (2006) Carcinogenesis , vol.27 , pp. 1105-1112
    • Kim, D.J.1    Prabhu, K.S.2    Gonzalez, F.J.3    Peters, J.M.4
  • 52
    • 0033625677 scopus 로고    scopus 로고
    • Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)
    • Peters, J. M., S. S. Lee, W. Li, J. M. Ward, O. Gavrilova, C. Everett, M. L. Reitman, L. D. Hudson, and F. J. Gonzalez. 2000. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol. Cell. Biol. 20: 5119-5128.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 5119-5128
    • Peters, J.M.1    Lee, S.S.2    Li, W.3    Ward, J.M.4    Gavrilova, O.5    Everett, C.6    Reitman, M.L.7    Hudson, L.D.8    Gonzalez, F.J.9
  • 54
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla, A., Y. Barak, L. Nagy, D. Liao, P. Tontonoz, and R. M. Evans. 2001. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat. Med. 7: 48-52.
    • (2001) Nat. Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 55
    • 0037289786 scopus 로고    scopus 로고
    • Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: Liver-X-receptor-specific inhibition of inflammation and primary cytokine production
    • Fowler, A. J., M. Y. Sheu, M. Schmuth, J. Kao, J. W. Fluhr, L. Rhein, J. L. Collins, T. M. Willson, D. J. Mangelsdorf, P. M. Elias, et al. 2003. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. J. Invest. Dermatol. 120: 246-255.
    • (2003) J. Invest. Dermatol , vol.120 , pp. 246-255
    • Fowler, A.J.1    Sheu, M.Y.2    Schmuth, M.3    Kao, J.4    Fluhr, J.W.5    Rhein, L.6    Collins, J.L.7    Willson, T.M.8    Mangelsdorf, D.J.9    Elias, P.M.10
  • 56
    • 0037324340 scopus 로고    scopus 로고
    • Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
    • Joseph, S. B., A. Castrillo, B. A. Laffitte, D. J. Mangelsdorf, and P. Tontonoz. 2003. Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9: 213-219.
    • (2003) Nat. Med , vol.9 , pp. 213-219
    • Joseph, S.B.1    Castrillo, A.2    Laffitte, B.A.3    Mangelsdorf, D.J.4    Tontonoz, P.5
  • 57
    • 0024325324 scopus 로고
    • Structure, function, and differentiation of the keratinocyte
    • Eckert, R. L. 1989. Structure, function, and differentiation of the keratinocyte. Physiol. Rev. 69: 1316-1346.
    • (1989) Physiol. Rev , vol.69 , pp. 1316-1346
    • Eckert, R.L.1
  • 58
    • 0025679060 scopus 로고
    • Epidermal differentiation: The bare essentials
    • Fuchs, E. 1990. Epidermal differentiation: the bare essentials. J. Cell Biol. 111: 2807-2814.
    • (1990) J. Cell Biol , vol.111 , pp. 2807-2814
    • Fuchs, E.1
  • 63
    • 33746394604 scopus 로고    scopus 로고
    • Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin
    • Kim, S., I. Hong, J. S. Hwang, J. K. Choi, H. S. Rho, D. H. Kim, I. Chang, S. H. Lee, M. O. Lee, and J. S. Hwang. 2006. Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin. Mol. Med. 12: 17-24.
    • (2006) Mol. Med , vol.12 , pp. 17-24
    • Kim, S.1    Hong, I.2    Hwang, J.S.3    Choi, J.K.4    Rho, H.S.5    Kim, D.H.6    Chang, I.7    Lee, S.H.8    Lee, M.O.9    Hwang, J.S.10
  • 65
    • 33644876516 scopus 로고    scopus 로고
    • Phytocomponents of triterpenoids, oleanolic acid and ursolic acid, regulated differently the processing of epidermal keratinocytes via PPAR-alpha pathway
    • Lee, H. K., G. W. Nam, S. H. Kim, and S. H. Lee. 2006. Phytocomponents of triterpenoids, oleanolic acid and ursolic acid, regulated differently the processing of epidermal keratinocytes via PPAR-alpha pathway. Exp. Dermatol. 15: 66-73.
    • (2006) Exp. Dermatol , vol.15 , pp. 66-73
    • Lee, H.K.1    Nam, G.W.2    Kim, S.H.3    Lee, S.H.4
  • 66
    • 34548150880 scopus 로고    scopus 로고
    • Simultaneous effect of ursolic acid and oleanolic acid on epidermal permeability barrier function and epidermal keratinocyte differentiation via peroxisome proliferator-activated receptor-alpha
    • Lim, S. W., S. P. Hong, S. W. Jeong, B. Kim, H. Bak, H. C. Ryoo, S. H. Lee, and S. K. Ahn. 2007. Simultaneous effect of ursolic acid and oleanolic acid on epidermal permeability barrier function and epidermal keratinocyte differentiation via peroxisome proliferator-activated receptor-alpha. J. Dermatol. 34: 625-634.
    • (2007) J. Dermatol , vol.34 , pp. 625-634
    • Lim, S.W.1    Hong, S.P.2    Jeong, S.W.3    Kim, B.4    Bak, H.5    Ryoo, H.C.6    Lee, S.H.7    Ahn, S.K.8
  • 67
    • 0037106540 scopus 로고    scopus 로고
    • Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors
    • Thuillier, P., A. R. Brash, J. P. Kehrer, J. B. Stimmel, L. M. Leesnitzer, P. Yang, R. A. Newman, and S. M. Fischer. 2002. Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors. Biochem. J. 366: 901-910.
    • (2002) Biochem. J , vol.366 , pp. 901-910
    • Thuillier, P.1    Brash, A.R.2    Kehrer, J.P.3    Stimmel, J.B.4    Leesnitzer, L.M.5    Yang, P.6    Newman, R.A.7    Fischer, S.M.8
  • 70
    • 0036829882 scopus 로고    scopus 로고
    • Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1, and AP2 families
    • Jang, S. I., and P. M. Steinert. 2002. Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1, and AP2 families. J. Biol. Chem. 277: 42268-42279.
    • (2002) J. Biol. Chem , vol.277 , pp. 42268-42279
    • Jang, S.I.1    Steinert, P.M.2
  • 71
    • 0034702882 scopus 로고    scopus 로고
    • Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression
    • Jessen, B. A., Q. Qin, and R. H. Rice. 2000. Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression. Gene. 254: 77-85.
    • (2000) Gene , vol.254 , pp. 77-85
    • Jessen, B.A.1    Qin, Q.2    Rice, R.H.3
  • 72
    • 0031910165 scopus 로고    scopus 로고
    • Effect of AP1 transcription factors on the regulation of transcription in normal human epidermal keratinocytes
    • Rossi, A., S. I. Jang, R. Ceci, P. M. Steinert, and N. G. Markova. 1998. Effect of AP1 transcription factors on the regulation of transcription in normal human epidermal keratinocytes. J. Invest. Dermatol. 110: 34-40.
    • (1998) J. Invest. Dermatol , vol.110 , pp. 34-40
    • Rossi, A.1    Jang, S.I.2    Ceci, R.3    Steinert, P.M.4    Markova, N.G.5
  • 74
    • 0036024023 scopus 로고    scopus 로고
    • Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma
    • Nickoloff, B. J., J. Z. Qin, V. Chaturvedi, M. F. Denning, B. Bonish, and L. Miele. 2002. Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma. Cell Death Differ. 9: 842-855.
    • (2002) Cell Death Differ , vol.9 , pp. 842-855
    • Nickoloff, B.J.1    Qin, J.Z.2    Chaturvedi, V.3    Denning, M.F.4    Bonish, B.5    Miele, L.6
  • 75
    • 37249053783 scopus 로고    scopus 로고
    • Thematic review series: Skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis
    • Feingold, K. R. 2007. Thematic review series: skin lipids. The role of epidermal lipids in cutaneous permeability barrier homeostasis. J. Lipid Res. 48: 2531-2546.
    • (2007) J. Lipid Res , vol.48 , pp. 2531-2546
    • Feingold, K.R.1
  • 76
    • 33644642167 scopus 로고    scopus 로고
    • Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: Liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing
    • Man, M. Q., E. H. Choi, M. Schmuth, D. Crumrine, Y. Uchida, P. M. Elias, W. M. Holleran, and K. R. Feingold. 2006. Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing. J. Invest. Dermatol. 126: 386-392.
    • (2006) J. Invest. Dermatol , vol.126 , pp. 386-392
    • Man, M.Q.1    Choi, E.H.2    Schmuth, M.3    Crumrine, D.4    Uchida, Y.5    Elias, P.M.6    Holleran, W.M.7    Feingold, K.R.8
  • 77
    • 33744798752 scopus 로고    scopus 로고
    • Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes
    • Calleja, C., N. Messaddeq, B. Chapellier, H. Yang, W. Krezel, M. Li, D. Metzger, B. Mascrez, K. Ohta, H. Kagechika, et al. 2006. Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes. Genes Dev. 20: 1525-1538.
    • (2006) Genes Dev , vol.20 , pp. 1525-1538
    • Calleja, C.1    Messaddeq, N.2    Chapellier, B.3    Yang, H.4    Krezel, W.5    Li, M.6    Metzger, D.7    Mascrez, B.8    Ohta, K.9    Kagechika, H.10
  • 78
    • 0034004910 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha enhances lipid metabolism in a skin equivalent model
    • Rivier, M., I. Castiel, I. Safonova, G. Ailhaud, and S. Michel. 2000. Peroxisome proliferator-activated receptor-alpha enhances lipid metabolism in a skin equivalent model. J. Invest. Dermatol. 114: 681-687.
    • (2000) J. Invest. Dermatol , vol.114 , pp. 681-687
    • Rivier, M.1    Castiel, I.2    Safonova, I.3    Ailhaud, G.4    Michel, S.5
  • 79
    • 22144488775 scopus 로고    scopus 로고
    • Harlequin ichthyosis unmasked: A defect of lipid transport
    • Hovnanian, A. 2005. Harlequin ichthyosis unmasked: a defect of lipid transport. J. Clin. Invest. 115: 1708-1710.
    • (2005) J. Clin. Invest , vol.115 , pp. 1708-1710
    • Hovnanian, A.1
  • 83
    • 0027316078 scopus 로고
    • Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function
    • Holleran, W. M., Y. Takagi, G. K. Menon, G. Legler, K. R. Feingold, and P. M. Elias. 1993. Processing of epidermal glucosylceramides is required for optimal mammalian cutaneous permeability barrier function. J. Clin. Invest. 91: 1656-1664.
    • (1993) J. Clin. Invest , vol.91 , pp. 1656-1664
    • Holleran, W.M.1    Takagi, Y.2    Menon, G.K.3    Legler, G.4    Feingold, K.R.5    Elias, P.M.6
  • 85
    • 0142074270 scopus 로고    scopus 로고
    • Cholesterol sulfate in human physiology: What's it all about?
    • Strott, C. A., and Y. Higashi. 2003. Cholesterol sulfate in human physiology: what's it all about? J. Lipid Res. 44: 1268-1278.
    • (2003) J. Lipid Res , vol.44 , pp. 1268-1278
    • Strott, C.A.1    Higashi, Y.2
  • 86
    • 30844464332 scopus 로고    scopus 로고
    • LXR and PPAR activators stimulate cholesterol sulfotransferase type 2 isoform 1b in human keratinocytes
    • Jiang, Y. J., P. Kim, P. M. Elias, and K. R. Feingold. 2005. LXR and PPAR activators stimulate cholesterol sulfotransferase type 2 isoform 1b in human keratinocytes. J. Lipid Res. 46: 2657-2666.
    • (2005) J. Lipid Res , vol.46 , pp. 2657-2666
    • Jiang, Y.J.1    Kim, P.2    Elias, P.M.3    Feingold, K.R.4
  • 87
    • 33845595443 scopus 로고    scopus 로고
    • Regulation of ABCA1 expression in human keratinocytes and murine epidermis
    • Jiang, Y. J., B. Lu, P. Kim, P. M. Elias, and K. R. Feingold. 2006. Regulation of ABCA1 expression in human keratinocytes and murine epidermis. J. Lipid Res. 47: 2248-2258.
    • (2006) J. Lipid Res , vol.47 , pp. 2248-2258
    • Jiang, Y.J.1    Lu, B.2    Kim, P.3    Elias, P.M.4    Feingold, K.R.5
  • 88
    • 0030835838 scopus 로고    scopus 로고
    • Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier
    • Hanley, K., Y. Jiang, D. Crumrine, N. M. Bass, R. Appel, P. M. Elias, M. L. Williams, and K. R. Feingold. 1997. Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier. J. Clin. Invest. 100: 705-712.
    • (1997) J. Clin. Invest , vol.100 , pp. 705-712
    • Hanley, K.1    Jiang, Y.2    Crumrine, D.3    Bass, N.M.4    Appel, R.5    Elias, P.M.6    Williams, M.L.7    Feingold, K.R.8
  • 90
    • 0029985932 scopus 로고    scopus 로고
    • The epidermal hyperplasia associated with repeated barrier disruption by acetone treatment or tape stripping cannot be attributed to increased water loss
    • Denda, M., L. C. Wood, S. Emami, C. Calhoun, B. E. Brown, P. M. Elias, and K. R. Feingold. 1996. The epidermal hyperplasia associated with repeated barrier disruption by acetone treatment or tape stripping cannot be attributed to increased water loss. Arch. Dermatol. Res. 288: 230-238.
    • (1996) Arch. Dermatol. Res , vol.288 , pp. 230-238
    • Denda, M.1    Wood, L.C.2    Emami, S.3    Calhoun, C.4    Brown, B.E.5    Elias, P.M.6    Feingold, K.R.7
  • 91
    • 0033832034 scopus 로고    scopus 로고
    • Keratinocyte differentiation in hyperproliferative epidermis: Topical application of PPARalpha activators restores tissue homeostasis
    • Komuves, L. G., K. Hanley, M. Q. Man, P. M. Elias, M. L. Williams, and K. R. Feingold. 2000. Keratinocyte differentiation in hyperproliferative epidermis: topical application of PPARalpha activators restores tissue homeostasis. J. Invest. Dermatol. 115: 361-367.
    • (2000) J. Invest. Dermatol , vol.115 , pp. 361-367
    • Komuves, L.G.1    Hanley, K.2    Man, M.Q.3    Elias, P.M.4    Williams, M.L.5    Feingold, K.R.6
  • 92
    • 33644644271 scopus 로고    scopus 로고
    • Alterations in skin and stratified epithelia by constitutively activated PPARalpha
    • Yang, Q., A. Yamada, S. Kimura, J. M. Peters, and F. J. Gonzalez. 2006. Alterations in skin and stratified epithelia by constitutively activated PPARalpha. J. Invest. Dermatol. 126: 374-385.
    • (2006) J. Invest. Dermatol , vol.126 , pp. 374-385
    • Yang, Q.1    Yamada, A.2    Kimura, S.3    Peters, J.M.4    Gonzalez, F.J.5
  • 93
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee, S. S., T. Pineau, J. Drago, E. J. Lee, J. W. Owens, D. L. Kroetz, P. M. Fernandez-Salguero, H. Westphal, and F. J. Gonzalez. 1995. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15: 3012-3022.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 94
    • 33644653240 scopus 로고    scopus 로고
    • P)PARsing epidermal development
    • Dubrac, S., and M. Schmuth. 2006. (P)PARsing epidermal development. J. Invest. Dermatol. 126: 241-242.
    • (2006) J. Invest. Dermatol , vol.126 , pp. 241-242
    • Dubrac, S.1    Schmuth, M.2
  • 95
    • 34147146967 scopus 로고    scopus 로고
    • Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes
    • Burdick, A. D., M. T. Bility, E. E. Girroir, A. N. Billin, T. M. Willson, F. J. Gonzalez, and J. M. Peters. 2007. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. Cell. Signal. 19: 1163-1171.
    • (2007) Cell. Signal , vol.19 , pp. 1163-1171
    • Burdick, A.D.1    Bility, M.T.2    Girroir, E.E.3    Billin, A.N.4    Willson, T.M.5    Gonzalez, F.J.6    Peters, J.M.7
  • 96
    • 26244443261 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation
    • Burdick, A. D., D. J. Kim, M. A. Peraza, F. J. Gonzalez, and J. M. Peters. 2006. The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation. Cell. Signal. 18: 9-20.
    • (2006) Cell. Signal , vol.18 , pp. 9-20
    • Burdick, A.D.1    Kim, D.J.2    Peraza, M.A.3    Gonzalez, F.J.4    Peters, J.M.5
  • 97
    • 15744366162 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity
    • Kim, D. J., I. A. Murray, A. M. Burns, F. J. Gonzalez, G. H. Perdew, and J. M. Peters. 2005. Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by down-regulation of kinase activity. J. Biol. Chem. 280: 9519-9527.
    • (2005) J. Biol. Chem , vol.280 , pp. 9519-9527
    • Kim, D.J.1    Murray, I.A.2    Burns, A.M.3    Gonzalez, F.J.4    Perdew, G.H.5    Peters, J.M.6
  • 98
    • 32344438786 scopus 로고    scopus 로고
    • Effects of di(2-ethylhexyl) phthalate, a widely used peroxisome proliferator and plasticizer, on cell growth in the human keratinocyte cell line NCTC 2544
    • Martinasso, G., M. Maggiora, A. Trombetta, R. A. Canuto, and G. Muzio. 2006. Effects of di(2-ethylhexyl) phthalate, a widely used peroxisome proliferator and plasticizer, on cell growth in the human keratinocyte cell line NCTC 2544. J. Toxicol. Environ. Health. 69: 353-365.
    • (2006) J. Toxicol. Environ. Health , vol.69 , pp. 353-365
    • Martinasso, G.1    Maggiora, M.2    Trombetta, A.3    Canuto, R.A.4    Muzio, G.5
  • 99
    • 0036771764 scopus 로고    scopus 로고
    • Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway
    • Di-Poi, N., N. S. Tan, L. Michalik, W. Wahli, and B. Desvergne. 2002. Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol. Cell. 10: 721-733.
    • (2002) Mol. Cell , vol.10 , pp. 721-733
    • Di-Poi, N.1    Tan, N.S.2    Michalik, L.3    Wahli, W.4    Desvergne, B.5
  • 101
    • 9744249460 scopus 로고    scopus 로고
    • Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes
    • He, G., P. Thuillier, and S. M. Fischer. 2004. Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes. J. Invest. Dermatol. 123: 1110-1119.
    • (2004) J. Invest. Dermatol , vol.123 , pp. 1110-1119
    • He, G.1    Thuillier, P.2    Fischer, S.M.3
  • 102
    • 33645902864 scopus 로고    scopus 로고
    • Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model
    • Demerjian, M., M. Q. Man, E. H. Choi, B. E. Brown, D. Crumrine, S. Chang, T. Mauro, P. M. Elias, and K. R. Feingold. 2006. Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model. Exp. Dermatol. 15: 154-160.
    • (2006) Exp. Dermatol , vol.15 , pp. 154-160
    • Demerjian, M.1    Man, M.Q.2    Choi, E.H.3    Brown, B.E.4    Crumrine, D.5    Chang, S.6    Mauro, T.7    Elias, P.M.8    Feingold, K.R.9
  • 104
    • 0032910469 scopus 로고    scopus 로고
    • Fish oil constituent docosahexaenoic acid selectively inhibits growth of human papillomavirus immortalized keratinocytes
    • Chen, D., and K. Auborn. 1999. Fish oil constituent docosahexaenoic acid selectively inhibits growth of human papillomavirus immortalized keratinocytes. Carcinogenesis. 20: 249-254.
    • (1999) Carcinogenesis , vol.20 , pp. 249-254
    • Chen, D.1    Auborn, K.2
  • 105
    • 23644452316 scopus 로고    scopus 로고
    • The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin
    • He, G., S. Muga, P. Thuillier, R. A. Lubet, and S. M. Fischer. 2005. The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin. Mol. Carcinog. 43: 198-206.
    • (2005) Mol. Carcinog , vol.43 , pp. 198-206
    • He, G.1    Muga, S.2    Thuillier, P.3    Lubet, R.A.4    Fischer, S.M.5
  • 107
    • 0034779322 scopus 로고    scopus 로고
    • Correlation of expression of cyclooxygenase-2, vascular endothelial growth factor, and peroxisome proliferator-activated receptor delta with head and neck squamous cell carcinoma
    • Jaeckel, E. C., S. Raja, J. Tan, S. K. Das, S. K. Dey, D. A. Girod, T. T. Tsue, and T. R. Sanford. 2001. Correlation of expression of cyclooxygenase-2, vascular endothelial growth factor, and peroxisome proliferator-activated receptor delta with head and neck squamous cell carcinoma. Arch. Otolaryngol. Head Neck Surg. 127: 1253-1259.
    • (2001) Arch. Otolaryngol. Head Neck Surg , vol.127 , pp. 1253-1259
    • Jaeckel, E.C.1    Raja, S.2    Tan, J.3    Das, S.K.4    Dey, S.K.5    Girod, D.A.6    Tsue, T.T.7    Sanford, T.R.8
  • 108
    • 17444371632 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors
    • Nijsten, T., E. Geluyckens, C. Colpaert, and J. Lambert. 2005. Peroxisome proliferator-activated receptors in squamous cell carcinoma and its precursors. J. Cutan. Pathol. 32: 340-347.
    • (2005) J. Cutan. Pathol , vol.32 , pp. 340-347
    • Nijsten, T.1    Geluyckens, E.2    Colpaert, C.3    Lambert, J.4
  • 112
    • 3242735499 scopus 로고    scopus 로고
    • The novel synthetic oleanane triterpenoid CDDO (2-cyano-3,12-dioxoolean-1,9-dien-28- oic acid) induces apoptosis in mycosis fungoides/Sezary syndrome cells
    • Zhang, C., X. Ni, M. Konopleva, M. Andreeff, and M. Duvic. 2004. The novel synthetic oleanane triterpenoid CDDO (2-cyano-3,12-dioxoolean-1,9-dien-28- oic acid) induces apoptosis in mycosis fungoides/Sezary syndrome cells. J. Invest. Dermatol. 123: 380-387.
    • (2004) J. Invest. Dermatol , vol.123 , pp. 380-387
    • Zhang, C.1    Ni, X.2    Konopleva, M.3    Andreeff, M.4    Duvic, M.5
  • 113
    • 33644878770 scopus 로고    scopus 로고
    • Improvement in psoriasis with rosiglitazone in a diabetic and a nondiabetic patient
    • Pershadsingh, H. A., S. C. Benson, and C. N. Ellis. 2005. Improvement in psoriasis with rosiglitazone in a diabetic and a nondiabetic patient. Skinmed. 4: 386-390.
    • (2005) Skinmed , vol.4 , pp. 386-390
    • Pershadsingh, H.A.1    Benson, S.C.2    Ellis, C.N.3
  • 114
    • 34250633274 scopus 로고    scopus 로고
    • Placebo response in two long-term randomized psoriasis studies that were negative for rosiglitazone
    • Ellis, C. N., J. N. Barker, A. E. Haig, C. A. Parker, S. Daly, and D. A. Jayawardene. 2007. Placebo response in two long-term randomized psoriasis studies that were negative for rosiglitazone. Am. J. Clin. Dermatol. 8: 93-102.
    • (2007) Am. J. Clin. Dermatol , vol.8 , pp. 93-102
    • Ellis, C.N.1    Barker, J.N.2    Haig, A.E.3    Parker, C.A.4    Daly, S.5    Jayawardene, D.A.6
  • 115
    • 17444404606 scopus 로고    scopus 로고
    • Pilot trial: Pioglitazone versus placebo in patients with plaque psoriasis (the P6)
    • Shafiq, N., S. Malhotra, P. Pandhi, M. Gupta, B. Kumar, and K. Sandhu. 2005. Pilot trial: pioglitazone versus placebo in patients with plaque psoriasis (the P6). Int. J. Dermatol. 44: 328-333.
    • (2005) Int. J. Dermatol , vol.44 , pp. 328-333
    • Shafiq, N.1    Malhotra, S.2    Pandhi, P.3    Gupta, M.4    Kumar, B.5    Sandhu, K.6
  • 116
    • 0037250963 scopus 로고    scopus 로고
    • Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis. A pilot study
    • Kuenzli, S., and J. H. Saurat. 2003. Effect of topical PPARbeta/delta and PPARgamma agonists on plaque psoriasis. A pilot study. Dermatology. 206: 252-256.
    • (2003) Dermatology , vol.206 , pp. 252-256
    • Kuenzli, S.1    Saurat, J.H.2
  • 117
    • 0041411241 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in cutaneous biology
    • Kuenzli, S., and J. H. Saurat. 2003. Peroxisome proliferator-activated receptors in cutaneous biology. Br. J. Dermatol. 149: 229-236.
    • (2003) Br. J. Dermatol , vol.149 , pp. 229-236
    • Kuenzli, S.1    Saurat, J.H.2
  • 118
    • 3042633732 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as new molecular targets in psoriasis
    • Kuenzli, S., and J. H. Saurat. 2004. Peroxisome proliferator-activated receptors as new molecular targets in psoriasis. Curr. Drug Targets. 3: 205-211.
    • (2004) Curr. Drug Targets , vol.3 , pp. 205-211
    • Kuenzli, S.1    Saurat, J.H.2
  • 119
    • 61849171959 scopus 로고    scopus 로고
    • New natural PPAR-alpha agonist for childhood atopic dermatitis: Dermocorticoid- sparing and quality of life improvement (Abstract)
    • Msika, P., C. De Belilovsky, B. Chadoutaud, and J. F. Nicolas. 2007. New natural PPAR-alpha agonist for childhood atopic dermatitis: dermocorticoid- sparing and quality of life improvement (Abstract). J. Am. Acad. Dermatol. 56: AB67.
    • (2007) J. Am. Acad. Dermatol , vol.56
    • Msika, P.1    De Belilovsky, C.2    Chadoutaud, B.3    Nicolas, J.F.4


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