-
1
-
-
0037039374
-
Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer
-
Barak Y., Liao D., He W., Ong E.S., Nelson M.C., Olefsky J.M., Boland R., Evans R.M. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc. Natl. Acad. Sci. USA. 99:2002;303-308.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 303-308
-
-
Barak, Y.1
Liao, D.2
He, W.3
Ong, E.S.4
Nelson, M.C.5
Olefsky, J.M.6
Boland, R.7
Evans, R.M.8
-
2
-
-
0035448879
-
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
-
Chen W.S., Xu P.Z., Gottlob K., Chen M.L., Sokol K., Shiyanova T., Roninson I., Weng W., Suzuki R., Tobe K.et al. Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev. 15:2001;2203-2208.
-
(2001)
Genes Dev.
, vol.15
, pp. 2203-2208
-
-
Chen, W.S.1
Xu, P.Z.2
Gottlob, K.3
Chen, M.L.4
Sokol, K.5
Shiyanova, T.6
Roninson, I.7
Weng, W.8
Suzuki, R.9
Tobe, K.10
-
3
-
-
0035914388
-
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho H., Thorvaldsen J.L., Chu Q., Feng F., Birnbaum M.J. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276:2001;38349-38352.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
4
-
-
0033305213
-
Ppars: Nuclear control of metabolism
-
Desvergne B., Wahli W. Ppars. nuclear control of metabolism Endocr. Rev. 20:1999;649-688.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 649-688
-
-
Desvergne, B.1
Wahli, W.2
-
5
-
-
0027278522
-
Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors
-
Dreyer C., Keller H., Mahfoudi A., Laudet V., Krey G., Wahli W. Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors. Biol. Cell. 77:1993;67-76.
-
(1993)
Biol. Cell
, vol.77
, pp. 67-76
-
-
Dreyer, C.1
Keller, H.2
Mahfoudi, A.3
Laudet, V.4
Krey, G.5
Wahli, W.6
-
6
-
-
0033912843
-
Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation
-
Filippa N., Sable C.L., Hemmings B.A., Van Obberghen E. Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation. Mol. Cell. Biol. 20:2000;5712-5721.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5712-5721
-
-
Filippa, N.1
Sable, C.L.2
Hemmings, B.A.3
Van Obberghen, E.4
-
7
-
-
0034676303
-
Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival
-
Flynn P., Wongdagger M., Zavar M., Dean N.M., Stokoe D. Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival. Curr. Biol. 10:2000;1439-1442.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1439-1442
-
-
Flynn, P.1
Wongdagger, M.2
Zavar, M.3
Dean, N.M.4
Stokoe, D.5
-
8
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
Frisch S.M., Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124:1994;619-626.
-
(1994)
J. Cell Biol.
, vol.124
, pp. 619-626
-
-
Frisch, S.M.1
Francis, H.2
-
9
-
-
0033596123
-
Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: Transgenics and knockouts
-
Gerondakis S., Grossmann M., Nakamura Y., Pohl T., Grumont R. Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function. transgenics and knockouts Oncogene. 18:1999;6888-6895.
-
(1999)
Oncogene
, vol.18
, pp. 6888-6895
-
-
Gerondakis, S.1
Grossmann, M.2
Nakamura, Y.3
Pohl, T.4
Grumont, R.5
-
10
-
-
0032960727
-
A central role of Bcl-X(L) in the regulation of keratinocyte survival by autocrine EGFR ligands
-
Jost M., Class R., Kari C., Jensen P.J., Rodeck U. A central role of Bcl-X(L) in the regulation of keratinocyte survival by autocrine EGFR ligands. J. Invest. Dermatol. 112:1999;443-449.
-
(1999)
J. Invest. Dermatol.
, vol.112
, pp. 443-449
-
-
Jost, M.1
Class, R.2
Kari, C.3
Jensen, P.J.4
Rodeck, U.5
-
11
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja A., Rodriguez-Viciana P., Wennstrom S., Warne P.H., Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16:1997;2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.2
Wennstrom, S.3
Warne, P.H.4
Downward, J.5
-
12
-
-
0035921419
-
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice
-
Michalik L., Desvergne B., Tan N.S., Basu-Modak S., Escher P., Rieusset J., Peters J.M., Kaya G., Gonzalez F.J., Zakany J.et al. Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J. Cell Biol. 154:2001;799-814.
-
(2001)
J. Cell Biol.
, vol.154
, pp. 799-814
-
-
Michalik, L.1
Desvergne, B.2
Tan, N.S.3
Basu-Modak, S.4
Escher, P.5
Rieusset, J.6
Peters, J.M.7
Kaya, G.8
Gonzalez, F.J.9
Zakany, J.10
-
13
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
Nicholson K.M., Anderson N.G. The protein kinase B/Akt signalling pathway in human malignancy. Cell. Signal. 14:2002;381-395.
-
(2002)
Cell. Signal.
, vol.14
, pp. 381-395
-
-
Nicholson, K.M.1
Anderson, N.G.2
-
14
-
-
0032516094
-
Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
-
Novak A., Hsu S.C., Leung-Hagesteijn C., Radeva G., Papkoff J., Montesano R., Roskelley C., Grosschedl R., Dedhar S. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc. Natl. Acad. Sci. USA. 95:1998;4374-4379.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4374-4379
-
-
Novak, A.1
Hsu, S.C.2
Leung-Hagesteijn, C.3
Radeva, G.4
Papkoff, J.5
Montesano, R.6
Roskelley, C.7
Grosschedl, R.8
Dedhar, S.9
-
15
-
-
0033517189
-
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes O.N., Mayo L.D., Gustin J.A., Pfeffer S.R., Pfeffer L.M., Donner D.B. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature. 401:1999;82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
16
-
-
0035167762
-
Peroxisome proliferator-activated receptors: Roles in tumorigenesis and chemoprevention in human cancer
-
Park B.H., Breyer B., He T.C. Peroxisome proliferator-activated receptors. roles in tumorigenesis and chemoprevention in human cancer Curr. Opin. Oncol. 13:2001;78-83.
-
(2001)
Curr. Opin. Oncol.
, vol.13
, pp. 78-83
-
-
Park, B.H.1
Breyer, B.2
He, T.C.3
-
17
-
-
0035873953
-
Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN
-
Patel L., Pass I., Coxon P., Downes C.P., Smith S.A., Macphee C.H. Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN. Curr. Biol. 11:2001;764-768.
-
(2001)
Curr. Biol.
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
18
-
-
0033625677
-
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)
-
Peters J.M., Lee S.S., Li W., Ward J.M., Gavrilova O., Everett C., Reitman M.L., Hudson L.D., Gonzalez F.J. Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta). Mol. Cell. Biol. 20:2000;5119-5128.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5119-5128
-
-
Peters, J.M.1
Lee, S.S.2
Li, W.3
Ward, J.M.4
Gavrilova, O.5
Everett, C.6
Reitman, M.L.7
Hudson, L.D.8
Gonzalez, F.J.9
-
19
-
-
0029823946
-
A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophils
-
Ptasznik A., Prossnitz E.R., Yoshikawa D., Smrcka A., Traynor-Kaplan A.E., Bokoch G.M. A tyrosine kinase signaling pathway accounts for the majority of phosphatidylinositol 3,4,5-trisphosphate formation in chemoattractant-stimulated human neutrophils. J. Biol. Chem. 271:1996;25204-25207.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25204-25207
-
-
Ptasznik, A.1
Prossnitz, E.R.2
Yoshikawa, D.3
Smrcka, A.4
Traynor-Kaplan, A.E.5
Bokoch, G.M.6
-
20
-
-
0026590541
-
Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells
-
Schreck R., Meier B., Mannel D.N., Droge W., Baeuerle P.A. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells. J. Exp. Med. 175:1992;1181-1194.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1181-1194
-
-
Schreck, R.1
Meier, B.2
Mannel, D.N.3
Droge, W.4
Baeuerle, P.A.5
-
21
-
-
0037012011
-
Functional roles of Akt signaling in mouse skin tumorigenesis
-
Segrelles C., Ruiz S., Perez P., Murga C., Santos M., Budunova I.V., Martinez J., Larcher F., Slaga T.J., Gutkind J.S.et al. Functional roles of Akt signaling in mouse skin tumorigenesis. Oncogene. 21:2002;53-64.
-
(2002)
Oncogene
, vol.21
, pp. 53-64
-
-
Segrelles, C.1
Ruiz, S.2
Perez, P.3
Murga, C.4
Santos, M.5
Budunova, I.V.6
Martinez, J.7
Larcher, F.8
Slaga, T.J.9
Gutkind, J.S.10
-
22
-
-
0035883151
-
NF-kappaB signaling pathways in mammalian and insect innate immunity
-
Silverman N., Maniatis T. NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15:2001;2321-2342.
-
(2001)
Genes Dev.
, vol.15
, pp. 2321-2342
-
-
Silverman, N.1
Maniatis, T.2
-
23
-
-
0034717285
-
Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60
-
Sonoda Y., Matsumoto Y., Funakoshi M., Yamamoto D., Hanks S.K., Kasahara T. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60. J. Biol. Chem. 275:2000;16309-16315.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16309-16315
-
-
Sonoda, Y.1
Matsumoto, Y.2
Funakoshi, M.3
Yamamoto, D.4
Hanks, S.K.5
Kasahara, T.6
-
24
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
Sternlicht M.D., Werb Z. How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17:2001;463-516.
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
25
-
-
0035893364
-
Critical roles of PPARβ/δ in keratinocyte response to inflammation
-
Tan N.S., Michalik L., Noy N., Yasmin R., Pacot C., Heim H., Flühmann B., Desvergne B., Wahli W. Critical roles of PPARβ/δ in keratinocyte response to inflammation. Genes Dev. 15:2001;3263-3277.
-
(2001)
Genes Dev.
, vol.15
, pp. 3263-3277
-
-
Tan, N.S.1
Michalik, L.2
Noy, N.3
Yasmin, R.4
Pacot, C.5
Heim, H.6
Flühmann, B.7
Desvergne, B.8
Wahli, W.9
-
26
-
-
0032079523
-
Protein kinase B and Rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway
-
Welch H., Eguinoa A., Stephens L.A., Hawkins P.T. Protein kinase B and Rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway. J. Biol. Chem. 273:1998;11248-11256.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 11248-11256
-
-
Welch, H.1
Eguinoa, A.2
Stephens, L.A.3
Hawkins, P.T.4
-
27
-
-
0033976586
-
Transfac: An integrated system for gene expression regulation
-
Wingender E., Chen X., Hehl R., Karas H., Liebich I., Matys V., Meinhardt T., Pruss M., Reuter I., Schacherer F. Transfac. an integrated system for gene expression regulation Nucleic Acids Res. 28:2000;316-319.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 316-319
-
-
Wingender, E.1
Chen, X.2
Hehl, R.3
Karas, H.4
Liebich, I.5
Matys, V.6
Meinhardt, T.7
Pruss, M.8
Reuter, I.9
Schacherer, F.10
-
28
-
-
0035969233
-
Integrin-linked kinase (ILK) and its interactors: A new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes
-
Wu C., Dedhar S. Integrin-linked kinase (ILK) and its interactors. a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes J. Cell Biol. 155:2001;505-510.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 505-510
-
-
Wu, C.1
Dedhar, S.2
-
29
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu X., Senechal K., Neshat M.S., Whang Y.E., Sawyers C.L. The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc. Natl. Acad. Sci. USA. 95:1998;15587-15591.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15587-15591
-
-
Wu, X.1
Senechal, K.2
Neshat, M.S.3
Whang, Y.E.4
Sawyers, C.L.5
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