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Volumn 16, Issue 10, 2007, Pages 844-852

Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit

Author keywords

Iipogenesis; Liver X receptors; Proliferation

Indexed keywords

LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; MESSENGER RNA;

EID: 34548484120     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2007.00612.x     Document Type: Article
Times cited : (63)

References (47)
  • 1
    • 0034518420 scopus 로고    scopus 로고
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
    • Repa J J, Mangelsdorf D J. The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol 2000: 16: 459-481.
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 459-481
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 2
    • 0036556688 scopus 로고    scopus 로고
    • LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis
    • Edwards P A, Kennedy M A, Mak P A. LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis. Vascul Pharmacol 2002: 38: 249-256.
    • (2002) Vascul Pharmacol , vol.38 , pp. 249-256
    • Edwards, P.A.1    Kennedy, M.A.2    Mak, P.A.3
  • 3
    • 0345461478 scopus 로고    scopus 로고
    • Putative metabolic effects of the liver X receptor (LXR)
    • Steffensen K R, Gustafsson J A. Putative metabolic effects of the liver X receptor (LXR). Diabetes 2004: 53 (Suppl. 1): S36-S42.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Steffensen, K.R.1    Gustafsson, J.A.2
  • 4
    • 0034872074 scopus 로고    scopus 로고
    • Hypolipidemic effects of selective liver X receptor alpha agonists
    • Song C, Liao S. Hypolipidemic effects of selective liver X receptor alpha agonists. Steroids 2001: 66: 673-681.
    • (2001) Steroids , vol.66 , pp. 673-681
    • Song, C.1    Liao, S.2
  • 5
    • 0035941285 scopus 로고    scopus 로고
    • Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages
    • Whitney K D, Watson M A, Goodwin B et al. Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages. J Biol Chem 2001: 276: 43509-43515.
    • (2001) J Biol Chem , vol.276 , pp. 43509-43515
    • Whitney, K.D.1    Watson, M.A.2    Goodwin, B.3
  • 7
    • 0033119162 scopus 로고    scopus 로고
    • Coactivator and corepressor complexes in nuclear receptor function
    • Xu L, Glass C K, Rosenfeld M G. Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev 1999: 9: 140-147.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 140-147
    • Xu, L.1    Glass, C.K.2    Rosenfeld, M.G.3
  • 8
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass C K, Rosenfeld M G. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 2000: 14: 121-141.
    • (2000) Genes Dev , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 9
    • 0033617520 scopus 로고    scopus 로고
    • Orphan nuclear receptors: Shifting endocrinology into reverse
    • Kliewer S A, Lehmann J M, Willson T M. Orphan nuclear receptors: shifting endocrinology into reverse. Science 1999: 284: 757-760.
    • (1999) Science , vol.284 , pp. 757-760
    • Kliewer, S.A.1    Lehmann, J.M.2    Willson, T.M.3
  • 10
    • 11244319578 scopus 로고    scopus 로고
    • Thematic review series: The immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors
    • Greaves D R, Gordon S. Thematic review series: The immune system and atherogenesis. Recent insights into the biology of macrophage scavenger receptors. J Lipid Res 2005: 46: 11-20.
    • (2005) J Lipid Res , vol.46 , pp. 11-20
    • Greaves, D.R.1    Gordon, S.2
  • 11
    • 0034126633 scopus 로고    scopus 로고
    • Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription
    • Hanley K, Ng DC, He SS et al. Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. J Invest Dermatol 2000: 114: 545-553.
    • (2000) J Invest Dermatol , vol.114 , pp. 545-553
    • Hanley, K.1    Ng, D.C.2    He, S.S.3
  • 12
    • 0032725472 scopus 로고    scopus 로고
    • Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators
    • Hanley K, Komuves L G, Bass N M et al. Fetal epidermal differentiation and barrier development In vivo is accelerated by nuclear hormone receptor activators. J Invest Dermatol 1999: 113: 788-795.
    • (1999) J Invest Dermatol , vol.113 , pp. 788-795
    • Hanley, K.1    Komuves, L.G.2    Bass, N.M.3
  • 13
    • 0036156083 scopus 로고    scopus 로고
    • Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis
    • Komuves L G, Schmuth M, Fowler A J et al. Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. J Invest Dermatol 2002: 118: 25-34.
    • (2002) J Invest Dermatol , vol.118 , pp. 25-34
    • Komuves, L.G.1    Schmuth, M.2    Fowler, A.J.3
  • 14
    • 3042684719 scopus 로고    scopus 로고
    • The effect of LXR activators on AP-1 proteins in keratinocytes
    • Schmuth M, Elias P M, Hanley K et al. The effect of LXR activators on AP-1 proteins in keratinocytes. J Invest Dermatol 2004: 123: 41-48.
    • (2004) J Invest Dermatol , vol.123 , pp. 41-48
    • Schmuth, M.1    Elias, P.M.2    Hanley, K.3
  • 15
    • 0037289786 scopus 로고    scopus 로고
    • Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: Liver-x-receptor-specific inhibition of inflammation and primary cytokine production
    • Fowler A J, Sheu M Y, Schmuth M et al. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: Liver-X-receptor-specific inhibition of inflammation and primary cytokine production. J Invest Dermatol 2003: 120: 246-255.
    • (2003) J Invest Dermatol , vol.120 , pp. 246-255
    • Fowler, A.J.1    Sheu, M.Y.2    Schmuth, M.3
  • 16
    • 0016729431 scopus 로고
    • Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells
    • Rheinwald J G, Green H. Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells. Cell 1975: 6: 331-343.
    • (1975) Cell , vol.6 , pp. 331-343
    • Rheinwald, J.G.1    Green, H.2
  • 18
    • 0021224749 scopus 로고
    • Induction of hair growth by implantation of cultured dermal papilla cells
    • Jahoda C A, Horne K A, Oliver R F. Induction of hair growth by implantation of cultured dermal papilla cells. Nature 1984: 311: 560-562.
    • (1984) Nature , vol.311 , pp. 560-562
    • Jahoda, C.A.1    Horne, K.A.2    Oliver, R.F.3
  • 20
    • 0033979731 scopus 로고    scopus 로고
    • Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
    • Dickson M A, Hahn W C, Ino Y et al. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 2000: 20: 1436-1447.
    • (2000) Mol Cell Biol , vol.20 , pp. 1436-1447
    • Dickson, M.A.1    Hahn, W.C.2    Ino, Y.3
  • 22
    • 0033397124 scopus 로고    scopus 로고
    • Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95)
    • Zouboulis C C, Seltmann H, Neitzel H, Orfanos C E. Establishment and characterization of an immortalized human sebaceous gland cell line (SZ95). J Invest Dermatol 1999: 113: 1011-1020.
    • (1999) J Invest Dermatol , vol.113 , pp. 1011-1020
    • Zouboulis, C.C.1    Seltmann, H.2    Neitzel, H.3    Orfanos, C.E.4
  • 23
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Muller M M, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989: 17: 6419.
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 24
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh E G, Dyer W J. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959: 37: 911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 25
    • 0025176917 scopus 로고
    • Organ maintenance of human sebaceous glands: In vitro effects of 13-cis retinoic acid and testosterone
    • Ridden J, Ferguson D, Kealey T. Organ maintenance of human sebaceous glands: In vitro effects of 13-cis retinoic acid and testosterone. J Cell Sci 1990: 1: 125-136.
    • (1990) J Cell Sci , vol.1 , pp. 125-136
    • Ridden, J.1    Ferguson, D.2    Kealey, T.3
  • 26
    • 27744537500 scopus 로고    scopus 로고
    • Insulin signaling in adipocytes differentiated from mouse stromal MC3T3-G2/PA6 cells
    • Morito S, Yaguchi K, Imaoa M et al. Insulin signaling in adipocytes differentiated from mouse stromal MC3T3-G2/PA6 cells. Biol Pharm Bull 2005: 28: 2040-2045.
    • (2005) Biol Pharm Bull , vol.28 , pp. 2040-2045
    • Morito, S.1    Yaguchi, K.2    Imaoa, M.3
  • 27
    • 0028110832 scopus 로고
    • Human hair growth in vitro: A model for the study of hair follicle biology
    • Philpott M P, Sanders D, Westgate G E, Kealey T. Human hair growth in vitro: A model for the study of hair follicle biology. J Dermatol Sci 1994: 7(Suppl): S55-S72.
    • (1994) J Dermatol Sci , vol.7 , Issue.SUPPL.
    • Philpott, M.P.1    Sanders, D.2    Westgate, G.E.3    Kealey, T.4
  • 28
    • 30844449427 scopus 로고    scopus 로고
    • Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha
    • Chen M, Beaven S, Tontonoz P. Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha. J Lipid Res 2005: 46: 2570-2579.
    • (2005) J Lipid Res , vol.46 , pp. 2570-2579
    • Chen, M.1    Beaven, S.2    Tontonoz, P.3
  • 29
    • 0037184935 scopus 로고    scopus 로고
    • Regulation of ALK-1 signaling by the nuclear receptor LXRbeta
    • Mo J, Fang S J, Chen W, Blobe G C. Regulation of ALK-1 signaling by the nuclear receptor LXRbeta. J Biol Chem 2002: 277: 50788-50794.
    • (2002) J Biol Chem , vol.277 , pp. 50788-50794
    • Mo, J.1    Fang, S.J.2    Chen, W.3    Blobe, G.C.4
  • 30
    • 33845658998 scopus 로고    scopus 로고
    • Nuclear localization of liver X receptor alpha and beta is differentially regulated
    • Prufer K, Boudreaux J. Nuclear localization of liver X receptor alpha and beta is differentially regulated. J Cell Biochem 2006: 100: 69-85.
    • (2006) J Cell Biochem , vol.100 , pp. 69-85
    • Prufer, K.1    Boudreaux, J.2
  • 31
    • 20044396738 scopus 로고    scopus 로고
    • Expression of the LXRalpha protein in human atherosclerotic lesions
    • Watanabe Y, Jiang S, Takabe W et al. Expression of the LXRalpha protein in human atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2005: 25: 622-627.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 622-627
    • Watanabe, Y.1    Jiang, S.2    Takabe, W.3
  • 32
    • 0028117755 scopus 로고
    • Ubiquitous receptor: A receptor that modulates gene activation by retinoic acid and thyroid hormone receptors
    • Song C, Kokontis J M, Hiipakka R A, Liao S. Ubiquitous receptor: A receptor that modulates gene activation by retinoic acid and thyroid hormone receptors. Proc Natl Acad Sci U S A 1994: 91: 10809-10813.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10809-10813
    • Song, C.1    Kokontis, J.M.2    Hiipakka, R.A.3    Liao, S.4
  • 33
    • 21644487430 scopus 로고    scopus 로고
    • Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries 10.1161/01.RES.0000150368.56660.4f
    • Blaschke F, Leppanen O, Takata Y et al. Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries 10.1161/ 01.RES.0000150368.56660.4f. Circ Res 2004: 95: e110-e123.
    • (2004) Circ Res , vol.95
    • Blaschke, F.1    Leppanen, O.2    Takata, Y.3
  • 34
    • 2442658405 scopus 로고    scopus 로고
    • Establishment of a monoclonal antibody for human LXRalpha: Detection of LXRalpha protein expression in human macrophages
    • Watanabe Y, Tanaka T, Uchiyama Y et al. Establishment of a monoclonal antibody for human LXRalpha: Detection of LXRalpha protein expression in human macrophages. Nucl Recept 2003: 1: 1.
    • (2003) Nucl Recept , vol.1 , pp. 1
    • Watanabe, Y.1    Tanaka, T.2    Uchiyama, Y.3
  • 35
    • 33645902864 scopus 로고    scopus 로고
    • Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model
    • Demerjian M, Man M Q, Choi E H et al. Topical treatment with thiazolidinediones, activators of peroxisome proliferator-activated receptor-gamma, normalizes epidermal homeostasis in a murine hyperproliferative disease model. Exp Dermatol 2006: 15: 154-160.
    • (2006) Exp Dermatol , vol.15 , pp. 154-160
    • Demerjian, M.1    Man, M.Q.2    Choi, E.H.3
  • 36
    • 0026279967 scopus 로고
    • The biochemistry and function of stratum corneum lipids
    • Schurer N Y, Elias P M. The biochemistry and function of stratum corneum lipids. Adv Lipid Res 1991: 24: 27-56.
    • (1991) Adv Lipid Res , vol.24 , pp. 27-56
    • Schurer, N.Y.1    Elias, P.M.2
  • 37
    • 0034710965 scopus 로고    scopus 로고
    • Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha
    • Venkateswaran A, Laffitte B A, Joseph S B et al. Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc Natl Acad Sci USA 2000: 97: 12097-12102.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12097-12102
    • Venkateswaran, A.1    Laffitte, B.A.2    Joseph, S.B.3
  • 38
    • 33845595443 scopus 로고    scopus 로고
    • Regulation of ABCA1 expression in human keratinocytes and murine epidermis
    • Jiang Y J, Lu B, Kim P, Elias P M, Feingold K R. Regulation of ABCA1 expression in human keratinocytes and murine epidermis. J Lipid Res 2006: 47: 2248-2258.
    • (2006) J Lipid Res , vol.47 , pp. 2248-2258
    • Jiang, Y.J.1    Lu, B.2    Kim, P.3    Elias, P.M.4    Feingold, K.R.5
  • 39
    • 0034669025 scopus 로고    scopus 로고
    • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
    • Repa J J, Liang G, Ou, J et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev 2000: 14: 2819-2830.
    • (2000) Genes Dev , vol.14 , pp. 2819-2830
    • Repa, J.J.1    Liang, G.2    Ou, J.3
  • 40
    • 0034669171 scopus 로고    scopus 로고
    • Role of LXRs in control of lipogenesis
    • Schultz J R, Tu H, Luk A et al. Role of LXRs in control of lipogenesis. Genes Dev 2000: 14: 2831-2838.
    • (2000) Genes Dev , vol.14 , pp. 2831-2838
    • Schultz, J.R.1    Tu, H.2    Luk, A.3
  • 41
    • 0037192797 scopus 로고    scopus 로고
    • Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
    • Joseph S B, Laffitte B A, Patel P H et al. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem 2002: 277: 11019-11025.
    • (2002) J Biol Chem , vol.277 , pp. 11019-11025
    • Joseph, S.B.1    Laffitte, B.A.2    Patel, P.H.3
  • 42
    • 0037289780 scopus 로고    scopus 로고
    • Differentiation and apoptosis in human immortalized sebocytes
    • Wrobel A, Seltmann H, Fimmel S et al. Differentiation and apoptosis in human immortalized sebocytes. J Invest Dermatol 2003: 120: 175-181.
    • (2003) J Invest Dermatol , vol.120 , pp. 175-181
    • Wrobel, A.1    Seltmann, H.2    Fimmel, S.3
  • 43
    • 0012617405 scopus 로고    scopus 로고
    • A new concept for acne therapy: A pilot study with zileuton, an oral 5-lipoxygenase inhibitor
    • Zouboulis C C, Nestoris S, Adler Y D et al. A new concept for acne therapy: A pilot study with zileuton, an oral 5-lipoxygenase inhibitor. Arch Dermatol 2003: 139: 668-670.
    • (2003) Arch Dermatol , vol.139 , pp. 668-670
    • Zouboulis, C.C.1    Nestoris, S.2    Adler, Y.D.3
  • 44
    • 30744436829 scopus 로고    scopus 로고
    • Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands
    • Alestas T, Ganceviciene R, Fimmel S, Muller-Decker K, Zouboulis C C. Enzymes involved in the biosynthesis of leukotriene B4 and prostaglandin E2 are active in sebaceous glands. J Mol Med 2006: 84: 75-87.
    • (2006) J Mol Med , vol.84 , pp. 75-87
    • Alestas, T.1    Ganceviciene, R.2    Fimmel, S.3    Muller-Decker, K.4    Zouboulis, C.C.5
  • 45
    • 33747330860 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors increase human sebum production
    • Trivedi N R, Cong Z, Nelson A M et al. Peroxisome proliferator-activated receptors increase human sebum production. J Invest Dermatol 2006: 126: 2002-2009.
    • (2006) J Invest Dermatol , vol.126 , pp. 2002-2009
    • Trivedi, N.R.1    Cong, Z.2    Nelson, A.M.3
  • 46
    • 33646488485 scopus 로고    scopus 로고
    • Liver X receptor preferentially activates de novo lipogenesis in human preadipocytes
    • Darimont C, Avanti O, Zbinden I et al. Liver X receptor preferentially activates de novo lipogenesis in human preadipocytes. Biochimie 2006: 3-4: 309-318.
    • (2006) Biochimie , vol.3-4 , pp. 309-318
    • Darimont, C.1    Avanti, O.2    Zbinden, I.3
  • 47
    • 33644642167 scopus 로고    scopus 로고
    • Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: Liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing
    • Man M Q, Choi E H, Schmuth M et al. Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: Liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing. J Invest Dermatol 2006: 126: 386-392.
    • (2006) J Invest Dermatol , vol.126 , pp. 386-392
    • Man, M.Q.1    Choi, E.H.2    Schmuth, M.3


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