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Volumn 123, Issue 2, 2004, Pages 380-387

The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in mycocis fungoides/sézary syndrome cells

Author keywords

bcl xL; Mycosis fungoides; PPAR ; RXR; S zary syndrome

Indexed keywords

2 CYANO 3 (12 DIOXOOLEAN) 1,9 DIEN 28 OIC ACID; BEXAROTENE; CASPASE 3; CD4 ANTIGEN; DIPEPTIDYL PEPTIDASE IV; DRUG VEHICLE; HORMONE RECEPTOR BLOCKING AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PROTEIN BCL 2; PROTEIN BCL XL; RETINOID X RECEPTOR; ROSIGLITAZONE; T 007; TRITERPENOID; UNCLASSIFIED DRUG;

EID: 3242735499     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.23207.x     Document Type: Article
Times cited : (23)

References (53)
  • 2
    • 0033402324 scopus 로고    scopus 로고
    • Extracorporeal photopheresis induces apoptosis in the lymphocytes of cutaneous T-cell lymphoma and graft-versus-host disease patients
    • Bladon J, Taylor PC: Extracorporeal photopheresis induces apoptosis in the lymphocytes of cutaneous T-cell lymphoma and graft-versus-host disease patients. Brit J Haematol 107:707-711, 1999
    • (1999) Brit J Haematol , vol.107 , pp. 707-711
    • Bladon, J.1    Taylor, P.C.2
  • 3
    • 0034522369 scopus 로고    scopus 로고
    • Decreased expression of Fas (APO-1/CD95) on peripheral blood CD4+ T lymphocytes in cutaneous T-cell lymphomas
    • Dereure O, Portales P, Clot J, Guilhou JJ: Decreased expression of Fas (APO-1/CD95) on peripheral blood CD4+ T lymphocytes in cutaneous T-cell lymphomas. Br J Dermatol 143:1205-1210, 2000
    • (2000) Br J Dermatol , vol.143 , pp. 1205-1210
    • Dereure, O.1    Portales, P.2    Clot, J.3    Guilhou, J.J.4
  • 4
    • 0028960578 scopus 로고
    • Expression of bcl-2 protein and Ki-67 nuclear proliferation antigen in benign and malignant cutaneous T-cell infiltrates
    • Dummer R, Michie SA, Kell D, et al: Expression of bcl-2 protein and Ki-67 nuclear proliferation antigen in benign and malignant cutaneous T-cell infiltrates. J Cutan Pathol 22:11-17, 1995
    • (1995) J Cutan Pathol , vol.22 , pp. 11-17
    • Dummer, R.1    Michie, S.A.2    Kell, D.3
  • 5
    • 0031298259 scopus 로고    scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase: A sensitive parameter to study cell death
    • Duriez PJ, Shah G: Cleavage of poly (ADP-ribose) polymerase: A sensitive parameter to study cell death. Biochem Cell Biol 75:337-349, 1997
    • (1997) Biochem Cell Biol , vol.75 , pp. 337-349
    • Duriez, P.J.1    Shah, G.2
  • 6
    • 0033966850 scopus 로고    scopus 로고
    • Emerging new therapies for cutaneous T-cell lymphoma
    • Duvic M, Cather JC: Emerging new therapies for cutaneous T-cell lymphoma. Dermatol Clin 18:147-156, 2000
    • (2000) Dermatol Clin , vol.18 , pp. 147-156
    • Duvic, M.1    Cather, J.C.2
  • 7
    • 0035340844 scopus 로고    scopus 로고
    • Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: Multinational phase II-III trial results
    • Duvic M, Hymes K, Heald P, et al: Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: Multinational phase II-III trial results. J Clin Oncol 19:2456-2471, 2001
    • (2001) J Clin Oncol , vol.19 , pp. 2456-2471
    • Duvic, M.1    Hymes, K.2    Heald, P.3
  • 8
    • 0034999546 scopus 로고    scopus 로고
    • Phase 2 and 3 clinical trial of oral bexarotene (Targretin capsules) for the treatment of refractory or persistent early-stage cutaneous T-cell lymphoma
    • Duvic M, Martin AG, Kim Y, et al: Phase 2 and 3 clinical trial of oral bexarotene (Targretin capsules) for the treatment of refractory or persistent early-stage cutaneous T-cell lymphoma. Arch Dermatol 137:581-593, 2001
    • (2001) Arch Dermatol , vol.137 , pp. 581-593
    • Duvic, M.1    Martin, A.G.2    Kim, Y.3
  • 9
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman BM, Chen J, Evans RM: Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94:4312-4317, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 10
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM: 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83:803-812, 1995
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 11
    • 0028873979 scopus 로고
    • Microculture tetrazolium assays: A comparison between two new tetrazolium salts, XTT and MTS
    • Goodwin CJ, Hoil SJ, Downes S, Marshall NJ: Microculture tetrazolium assays: A comparison between two new tetrazolium salts, XTT and MTS. J Immunol Methods 179:95-103, 1995
    • (1995) J Immunol Methods , vol.179 , pp. 95-103
    • Goodwin, C.J.1    Hoil, S.J.2    Downes, S.3    Marshall, N.J.4
  • 12
    • 0019787147 scopus 로고
    • Human CTCL and leukemia cell lines produce and respond to T cell growth factor
    • Gootenberg JE, Ruscetti FW, Mier JW, Gazdar A, Gallo RC: Human CTCL and leukemia cell lines produce and respond to T cell growth factor. J Exp Med 154:1403-1418, 1981
    • (1981) J Exp Med , vol.154 , pp. 1403-1418
    • Gootenberg, J.E.1    Ruscetti, F.W.2    Mier, J.W.3    Gazdar, A.4    Gallo, R.C.5
  • 13
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman JA: Apoptosis induced by anticancer drugs. Cancer Metast Rev 11:121-139, 1992
    • (1992) Cancer Metast Rev , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 14
    • 0034025671 scopus 로고    scopus 로고
    • Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages
    • Honda T, Gribble GW, Suh N, et al: Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages. J Med Chem 43:1866-1877, 2000
    • (2000) J Med Chem , vol.43 , pp. 1866-1877
    • Honda, T.1    Gribble, G.W.2    Suh, N.3
  • 15
    • 0034077629 scopus 로고    scopus 로고
    • The novel triterpenoid 2-cyano-3,12-dioxoolean-1, 9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism
    • Ito Y, Pandey P, Place A, et al: The novel triterpenoid 2-cyano-3,12-dioxoolean-1, 9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism. Cell Growth Differ 11:261-267, 2000
    • (2000) Cell Growth Differ , vol.11 , pp. 261-267
    • Ito, Y.1    Pandey, P.2    Place, A.3
  • 16
    • 0035037586 scopus 로고    scopus 로고
    • The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism
    • Ito Y, Pandey P, Sporn MB, Datta R, Kharbanda S, Kufe D: The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism. Mol Pharmacol 59:1094-1099, 2001
    • (2001) Mol Pharmacol , vol.59 , pp. 1094-1099
    • Ito, Y.1    Pandey, P.2    Sporn, M.B.3    Datta, R.4    Kharbanda, S.5    Kufe, D.6
  • 17
    • 0034813796 scopus 로고    scopus 로고
    • Apoptosis and cutaneous T cell lymphoma
    • Kacinski BM, Flick M: Apoptosis and cutaneous T cell lymphoma. Ann NY Acad Sci 941:194-199, 2001
    • (2001) Ann NY Acad Sci , vol.941 , pp. 194-199
    • Kacinski, B.M.1    Flick, M.2
  • 18
    • 0028021416 scopus 로고
    • Mycosis fungoides: Expression of c-myc p62, p53, bcl-2 and PCNA proteins and absence of association with Epstein-Barr virus
    • Kanavaros P, Ioannidou D, Tzardi M, et al: Mycosis fungoides: Expression of c-myc p62, p53, bcl-2 and PCNA proteins and absence of association with Epstein-Barr virus. Pathol Res Pract 190:767-774, 1994
    • (1994) Pathol Res Pract , vol.190 , pp. 767-774
    • Kanavaros, P.1    Ioannidou, D.2    Tzardi, M.3
  • 19
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Brit J Cancer 26:239-257, 1972
    • (1972) Brit J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 20
    • 0034721937 scopus 로고    scopus 로고
    • Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators
    • Kodera Y, Takeyama K, Murayama A, et al: Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators. J Biol Chem 275:33201-33204, 2000
    • (2000) J Biol Chem , vol.275 , pp. 33201-33204
    • Kodera, Y.1    Takeyama, K.2    Murayama, A.3
  • 21
    • 0141507973 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells
    • Lapillonne H, Konopleva M, Tsao T, et al: Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells. Cancer Res 63:5926-5939, 2003
    • (2003) Cancer Res , vol.63 , pp. 5926-5939
    • Lapillonne, H.1    Konopleva, M.2    Tsao, T.3
  • 22
    • 18844467411 scopus 로고    scopus 로고
    • T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities
    • Lee G, Elwood F, McNally J, et al: T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J Biol Chem 277:19649-19657, 2002
    • (2002) J Biol Chem , vol.277 , pp. 19649-19657
    • Lee, G.1    Elwood, F.2    McNally, J.3
  • 23
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 270:12953-12956, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 24
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf DJ, Evans RM: The RXR heterodimers and orphan receptors. Cell 83:841-850, 1995
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 25
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • Mangelsdorf DJ, Thummel C, Beato M, et al: The nuclear receptor superfamily: The second decade. Cell 83:835-839, 1995
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1    Thummel, C.2    Beato, M.3
  • 27
    • 17444442152 scopus 로고    scopus 로고
    • Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
    • Mukherjee R, Davies PJ, Crombie DL, et al: Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature 386:407-410, 1997
    • (1997) Nature , vol.386 , pp. 407-410
    • Mukherjee, R.1    Davies, P.J.2    Crombie, D.L.3
  • 28
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139:271-279, 1991
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi5
  • 29
    • 0032505096 scopus 로고    scopus 로고
    • Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
    • Nolte RT, Wisely GB, Westin S, et al: Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature 395:137-143, 1998
    • (1998) Nature , vol.395 , pp. 137-143
    • Nolte, R.T.1    Wisely, G.B.2    Westin, S.3
  • 30
    • 0344389027 scopus 로고    scopus 로고
    • Caspases: The proteases of the apoptotic pathway
    • Nunez G, Benedict MA, Hu Y, Inohara N: Caspases: The proteases of the apoptotic pathway. Oncogene 17:3237-3245, 1998
    • (1998) Oncogene , vol.17 , pp. 3237-3245
    • Nunez, G.1    Benedict, M.A.2    Hu, Y.3    Inohara, N.4
  • 31
    • 0035133039 scopus 로고    scopus 로고
    • Expression of apoptosis markers on peripheral blood lymphocytes from patients with cutaneous T-cell lymphoma during extracorporeal photochemotherapy
    • Osella-Aate S, Zaccagna A, Savoia P, Quaglino P, Salomone B, Bernengo MG: Expression of apoptosis markers on peripheral blood lymphocytes from patients with cutaneous T-cell lymphoma during extracorporeal photochemotherapy. J Am Acad Dermatol 44:40-47, 2001
    • (2001) J Am Acad Dermatol , vol.44 , pp. 40-47
    • Osella-Aate, S.1    Zaccagna, A.2    Savoia, P.3    Quaglino, P.4    Salomone, B.5    Bernengo, M.G.6
  • 32
    • 0037108441 scopus 로고    scopus 로고
    • The triterpenoid CDDO induces apoptosis in refractory CLL B cells
    • Pedersen IM, Kitada S, Schimmer A, et al: The triterpenoid CDDO induces apoptosis in refractory CLL B cells. Blood 100:2965-2972, 2002
    • (2002) Blood , vol.100 , pp. 2965-2972
    • Pedersen, I.M.1    Kitada, S.2    Schimmer, A.3
  • 33
    • 0020682240 scopus 로고
    • Isolation and transmission of human retrovirus (HTLV)
    • Popovic M, Sarin PS, Robert-Gurroff M: Isolation and transmission of human retrovirus (HTLV). Science 219:856-859, 1983
    • (1983) Science , vol.219 , pp. 856-859
    • Popovic, M.1    Sarin, P.S.2    Robert-Gurroff, M.3
  • 34
    • 0032409781 scopus 로고    scopus 로고
    • Bcl-2 family proteins
    • Reed JC: Bcl-2 family proteins. Oncogene 17:3225-3236, 1998
    • (1998) Oncogene , vol.17 , pp. 3225-3236
    • Reed, J.C.1
  • 36
    • 0037053358 scopus 로고    scopus 로고
    • The novel triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells
    • Stadheim TA, Suh N, Ganju N, Sporn M, Eastman A: The novel triterpenoid 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells. J Biol Chem 277:16448-16455, 2002
    • (2002) J Biol Chem , vol.277 , pp. 16448-16455
    • Stadheim, T.A.1    Suh, N.2    Ganju, N.3    Sporn, M.4    Eastman, A.5
  • 37
    • 0025739231 scopus 로고
    • Establishment of an IL-2 independent human T-cell line possessing only the p70 IL-2 receptor
    • Starkebaum G, Loughran TP, Waters CA, Ruscetti FW: Establishment of an IL-2 independent human T-cell line possessing only the p70 IL-2 receptor. Int J Cancer 49:246-253, 1991
    • (1991) Int J Cancer , vol.49 , pp. 246-253
    • Starkebaum, G.1    Loughran, T.P.2    Waters, C.A.3    Ruscetti, F.W.4
  • 38
    • 17144439794 scopus 로고    scopus 로고
    • Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages
    • Suh N, Honda T, Finlay HJ, et al: Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages. Cancer Res 58:717-723, 1998
    • (1998) Cancer Res , vol.58 , pp. 717-723
    • Suh, N.1    Honda, T.2    Finlay, H.J.3
  • 39
    • 0037444161 scopus 로고    scopus 로고
    • Synthetic triterpenoids enhance transforming growth factor β/Smad signaling
    • Suh N, Roberts AB, Birkey Reffey S, et al: Synthetic triterpenoids enhance transforming growth factor β/Smad signaling. Cancer Res 63:1371-1376, 2003
    • (2003) Cancer Res , vol.63 , pp. 1371-1376
    • Suh, N.1    Roberts, A.B.2    Birkey Reffey, S.3
  • 40
    • 0033555614 scopus 로고    scopus 로고
    • A novel synthetic oleanane triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity
    • Suh N, Wang Y, Honda T, et al: A novel synthetic oleanane triterpenoid, 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity. Cancer Res 15:336-341, 1999
    • (1999) Cancer Res , vol.15 , pp. 336-341
    • Suh, N.1    Wang, Y.2    Honda, T.3
  • 41
    • 0035049060 scopus 로고    scopus 로고
    • Apoptosis and its clinical impact
    • Synderman CH: Apoptosis and its clinical impact. Head and Neck 23:409-425, 2001
    • (2001) Head and Neck , vol.23 , pp. 409-425
    • Synderman, C.H.1
  • 42
    • 0032540012 scopus 로고    scopus 로고
    • PPAR gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM: PPAR gamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93:241-252, 1998
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 43
    • 0009285497 scopus 로고    scopus 로고
    • Targeted induction of apoptosis in leukemias by PPAR gamma ligation
    • Tsao T, Konopleva M, Sporn MB, Andreeff M: Targeted induction of apoptosis in leukemias by PPAR gamma ligation. Blood 98:568a, 2001
    • (2001) Blood , vol.98
    • Tsao, T.1    Konopleva, M.2    Sporn, M.B.3    Andreeff, M.4
  • 44
    • 0032411878 scopus 로고    scopus 로고
    • CD95 mediated Tcell apoptosis and its relevance to immune deviation
    • Varadachary AS, Salgame P: CD95 mediated Tcell apoptosis and its relevance to immune deviation. Oncogene 17:3271-3276, 1998
    • (1998) Oncogene , vol.17 , pp. 3271-3276
    • Varadachary, A.S.1    Salgame, P.2
  • 45
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled annexin V
    • Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C: A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled annexin V. J Immunol Methods 184:39-51, 1995
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 46
    • 0033777347 scopus 로고    scopus 로고
    • A synthetic triterpenoid, 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma
    • Wang Y, Porter WW, Suh N, et al: A synthetic triterpenoid, 2-cyano-3, 12-dioxooleana-1, 9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma. Mol Endocrinol 14:1550-1556, 2000
    • (2000) Mol Endocrinol , vol.14 , pp. 1550-1556
    • Wang, Y.1    Porter, W.W.2    Suh, N.3
  • 47
    • 0030630211 scopus 로고    scopus 로고
    • Apoptosis: An overview of the process and its relevance in disease
    • Webb SJ, Harrison DJ, Wyllie AH: Apoptosis: An overview of the process and its relevance in disease. Adv Pharmacol 41:1-34, 1997
    • (1997) Adv Pharmacol , vol.41 , pp. 1-34
    • Webb, S.J.1    Harrison, D.J.2    Wyllie, A.H.3
  • 48
    • 0032505066 scopus 로고    scopus 로고
    • Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators
    • Westin S, Kurokawa R, Nolte RT, et al: Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature 395:199-202, 1998
    • (1998) Nature , vol.395 , pp. 199-202
    • Westin, S.1    Kurokawa, R.2    Nolte, R.T.3
  • 49
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang Y, Liu X, Bahalla K, et al: Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked. Science 275:1129-1131, 1997
    • (1997) Science , vol.275 , pp. 1129-1131
    • Yang, Y.1    Liu, X.2    Bahalla, K.3
  • 50
    • 0030036510 scopus 로고    scopus 로고
    • Apoptosis induction by ultraviolet light A and photochemotherapy in cutaneous T-cell lymphoma: Relevance to mechanism of therapeutic action
    • Yoo EK, Rook AH, Elenitsas R, Gasparro FP, Vowels BR: Apoptosis induction by ultraviolet light A and photochemotherapy in cutaneous T-cell lymphoma: Relevance to mechanism of therapeutic action. J Invest Dermatol 107:235-242, 1996
    • (1996) J Invest Dermatol , vol.107 , pp. 235-242
    • Yoo, E.K.1    Rook, A.H.2    Elenitsas, R.3    Gasparro, F.P.4    Vowels, B.R.5
  • 51
    • 0036096774 scopus 로고    scopus 로고
    • Induction of apoptosis by bexarotene in cutaneous T-cell lymphoma cells: Relevance to mechanism of therapeutic action
    • Zhang CL, Hazarika P, Ni X, Weidner DA, Duvic M: Induction of apoptosis by bexarotene in cutaneous T-cell lymphoma cells: Relevance to mechanism of therapeutic action. Clin Cancer Res 8:1234-1240, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 1234-1240
    • Zhang, C.L.1    Hazarika, P.2    Ni, X.3    Weidner, D.A.4    Duvic, M.5
  • 52
  • 53
    • 0033842372 scopus 로고    scopus 로고
    • Expression of Fas and Fas-ligand in primary cutaneous T-cell lymphoma (CTCL): Association between lack of Fas expression and aggressive types of CTCL
    • Zoi-Toli O, Vermeer MH, De Vries D, Van Beek P, Meijer CJLM, Willemze R: Expression of Fas and Fas-ligand in primary cutaneous T-cell lymphoma (CTCL): Association between lack of Fas expression and aggressive types of CTCL. Br J Dermatol 143:313-319, 2000
    • (2000) Br J Dermatol , vol.143 , pp. 313-319
    • Zoi-Toli, O.1    Vermeer, M.H.2    De Vries, D.3    Van Beek, P.4    Meijer, C.J.L.M.5    Willemze, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.