메뉴 건너뛰기




Volumn 50, Issue 4, 2004, Pages 1305-1318

Disruption of Transforming Growth Factor β Signaling and Profibrotic Responses in Normal Skin Fibroblasts by Peroxisome Proliferator-Activated Receptor γ

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; RECEPTOR BLOCKING AGENT; SMAD PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 1842733168     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.20104     Document Type: Article
Times cited : (185)

References (59)
  • 1
    • 0036838772 scopus 로고    scopus 로고
    • Pathogenesis of fibrosis: Role of TGFβ and CTGF
    • Ihn H. Pathogenesis of fibrosis: role of TGFβ and CTGF. Curr Opin Rheumatol 2002;14:681-5.
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 681-685
    • Ihn, H.1
  • 2
    • 0033788161 scopus 로고    scopus 로고
    • Role of apoptosis and transforming growth factor β1 in fibroblast selection and activation in systemic sclerosis
    • Jelaska A, Korn JH. Role of apoptosis and transforming growth factor β1 in fibroblast selection and activation in systemic sclerosis. Arthritis Rheum 2000;43:2230-9.
    • (2000) Arthritis Rheum , vol.43 , pp. 2230-2239
    • Jelaska, A.1    Korn, J.H.2
  • 4
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGF-β/ Smad signaling system
    • Massague J, Wotton D. Transcriptional control by the TGF-β/ Smad signaling system. EMBO J 2002;19:1745-54.
    • (2002) EMBO J , vol.19 , pp. 1745-1754
    • Massague, J.1    Wotton, D.2
  • 5
    • 0032921867 scopus 로고    scopus 로고
    • Stimulation of type I collagen transcription in human skin fibroblasts by TGF-β: Involvement of SMAD 3
    • Chen SJ, Yuan W, Mori Y, Levenson A, Trojanowska M, Varga J. Stimulation of type I collagen transcription in human skin fibroblasts by TGF-β: involvement of SMAD 3. J Invest Dermatol 1999;112:49-57.
    • (1999) J Invest Dermatol , vol.112 , pp. 49-57
    • Chen, S.J.1    Yuan, W.2    Mori, Y.3    Levenson, A.4    Trojanowska, M.5    Varga, J.6
  • 6
    • 0034011221 scopus 로고    scopus 로고
    • Interaction of Smad3 with a proximal Smad-binding element of the human α2(I) procollagen gene promoter required for transcriptional activation by TGF-β
    • Chen SJ, Yuan W, Lo S, Trojanowska M, Varga J. Interaction of Smad3 with a proximal Smad-binding element of the human α2(I) procollagen gene promoter required for transcriptional activation by TGF-β. J Cell Physiol 2000;183:381-92.
    • (2000) J Cell Physiol , vol.183 , pp. 381-392
    • Chen, S.J.1    Yuan, W.2    Lo, S.3    Trojanowska, M.4    Varga, J.5
  • 7
    • 0034691764 scopus 로고    scopus 로고
    • SMAD-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-β involves functional cooperation with p300/CBP transcriptional coactivators
    • Ghosh AK, Yuan W, Mori Y, Varga J. SMAD-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-β involves functional cooperation with p300/CBP transcriptional coactivators. Oncogene 2000;19:3546-55.
    • (2000) Oncogene , vol.19 , pp. 3546-3555
    • Ghosh, A.K.1    Yuan, W.2    Mori, Y.3    Varga, J.4
  • 8
    • 0035815696 scopus 로고    scopus 로고
    • Antagonistic regulation of type I collagen gene expression by interferon-γ and transforming growth factor-β: Integration at the level of p300/CBP transcriptional coactivators
    • Ghosh AK, Yuan W, Mori Y, Chen SJ, Varga J. Antagonistic regulation of type I collagen gene expression by interferon-γ and transforming growth factor-β: integration at the level of p300/CBP transcriptional coactivators. J Biol Chem 2001;276:11041-8.
    • (2001) J Biol Chem , vol.276 , pp. 11041-11048
    • Ghosh, A.K.1    Yuan, W.2    Mori, Y.3    Chen, S.J.4    Varga, J.5
  • 9
    • 0038004796 scopus 로고    scopus 로고
    • Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts
    • Mori Y, Chen SJ, Varga J. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts. Arthritis Rheum 2003;48:1964-78.
    • (2003) Arthritis Rheum , vol.48 , pp. 1964-1978
    • Mori, Y.1    Chen, S.J.2    Varga, J.3
  • 10
    • 0036064618 scopus 로고    scopus 로고
    • Scleroderma and SMADs: Dysfunctional SMAD family dynamics culminating in fibrosis
    • Varga J. Scleroderma and SMADs: dysfunctional SMAD family dynamics culminating in fibrosis. Arthritis Rheum 2002;46:1703-13.
    • (2002) Arthritis Rheum , vol.46 , pp. 1703-1713
    • Varga, J.1
  • 11
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR γ2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPAR γ2, a lipid-activated transcription factor. Cell 1994;79:1147-56.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 12
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J, Moller DE. The mechanisms of action of PPARs. Annu Rev Med 2002;53:409-35.
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 13
    • 0035053973 scopus 로고    scopus 로고
    • Cyclopentenone prostaglandins: New insights on biological activities and cellular targets
    • Straus DS, Glass CK. Cyclopentenone prostaglandins: new insights on biological activities and cellular targets. Med Res Rev 2001;21:185-210.
    • (2001) Med Res Rev , vol.21 , pp. 185-210
    • Straus, D.S.1    Glass, C.K.2
  • 14
    • 0032505066 scopus 로고    scopus 로고
    • Interaction controlling the assembly of nuclear-receptor heterodimers and co-activators
    • Westin S, Kurokawa R, Nolte RT, Wisely GB, McInerney EM, Rose DW, et al. Interaction controlling the assembly of nuclear-receptor heterodimers and co-activators. Nature 1998;395:199-202.
    • (1998) Nature , vol.395 , pp. 199-202
    • Westin, S.1    Kurokawa, R.2    Nolte, R.T.3    Wisely, G.B.4    McInerney, E.M.5    Rose, D.W.6
  • 15
    • 0030771852 scopus 로고    scopus 로고
    • DNA binding properties of peroxisome proliferators-activated receptor subtypes on various natural peroxisome proliferators response elements
    • Juge-Aubry C, Pernin A, Favez T, Burger AG, Wahli W, Meier CA, et al. DNA binding properties of peroxisome proliferators-activated receptor subtypes on various natural peroxisome proliferators response elements. J Biol Chem 1997;272:25252-9.
    • (1997) J Biol Chem , vol.272 , pp. 25252-25259
    • Juge-Aubry, C.1    Pernin, A.2    Favez, T.3    Burger, A.G.4    Wahli, W.5    Meier, C.A.6
  • 16
    • 0032475922 scopus 로고    scopus 로고
    • Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages
    • Chinetti G, Griglio S, Antonucci M, Torra IP, Delerive P, Majd Z, et al. Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages. J Biol Chem 1998;273:25573-80.
    • (1998) J Biol Chem , vol.273 , pp. 25573-25580
    • Chinetti, G.1    Griglio, S.2    Antonucci, M.3    Torra, I.P.4    Delerive, P.5    Majd, Z.6
  • 19
    • 0036569446 scopus 로고    scopus 로고
    • 2 in activated human astrocytes, but not in human brain macrophages
    • 2 in activated human astrocytes, but not in human brain macrophages. J Immun 2002;168:4747-55.
    • (2002) J Immun , vol.168 , pp. 4747-4755
    • Janabi, N.1
  • 20
    • 0037428314 scopus 로고    scopus 로고
    • 2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-γ-independent mechanism
    • 2 inhibits the expression of proinflammatory genes in human blood monocytes via a PPAR-γ-independent mechanism. Biochem Biophys Res Commun 2003;302:415-20.
    • (2003) Biochem Biophys Res Commun , vol.302 , pp. 415-420
    • Hinz, B.1    Brune, K.2    Pahl, A.3
  • 21
    • 0037233828 scopus 로고    scopus 로고
    • Rapid induction of peroxisome proliferator-activated receptor γ expression in human monocytes by monosodium urate monohydrate crystals
    • Akahoshi T, Namai R, Murakami Y, Watanabe M, Matsui T, Nishimura A, et al. Rapid induction of peroxisome proliferator-activated receptor γ expression in human monocytes by monosodium urate monohydrate crystals. Arthritis Rheum 2003;48:231-9.
    • (2003) Arthritis Rheum , vol.48 , pp. 231-239
    • Akahoshi, T.1    Namai, R.2    Murakami, Y.3    Watanabe, M.4    Matsui, T.5    Nishimura, A.6
  • 22
    • 0037066768 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is induced in monocytes by peroxisome proliferators activated receptor γ and oxidized alkyl phospholipids from oxidized low density lipoprotein
    • Pontsler AV, Hilaire AS, Marathe GK, Zimmerman GA, McIntyre TM. Cyclooxygenase-2 is induced in monocytes by peroxisome proliferators activated receptor γ and oxidized alkyl phospholipids from oxidized low density lipoprotein. J Biol Chem 2002;277: 13029-36.
    • (2002) J Biol Chem , vol.277 , pp. 13029-13036
    • Pontsler, A.V.1    Hilaire, A.S.2    Marathe, G.K.3    Zimmerman, G.A.4    McIntyre, T.M.5
  • 23
    • 0036230990 scopus 로고    scopus 로고
    • Troglitazone suppresses the secretion of type I collagen by mesangial cells in vitro
    • Routh RE, Johnson JH, McCarthy KJ. Troglitazone suppresses the secretion of type I collagen by mesangial cells in vitro. Kidney Int 2002;61:1365-76.
    • (2002) Kidney Int , vol.61 , pp. 1365-1376
    • Routh, R.E.1    Johnson, J.H.2    McCarthy, K.J.3
  • 25
    • 0036082703 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
    • Galli A, Crabb DW, Ceni E, Salzano R, Mello T, Svegliati-Baroni G, et al. Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology 2002;122:1924-40.
    • (2002) Gastroenterology , vol.122 , pp. 1924-1940
    • Galli, A.1    Crabb, D.W.2    Ceni, E.3    Salzano, R.4    Mello, T.5    Svegliati-Baroni, G.6
  • 27
    • 0034680787 scopus 로고    scopus 로고
    • Peroxisome proliferators-activated receptor and hepatic stellate cell activation
    • Miyahara T, Schrum L, Rippe R, Xiong S, Yee HF Jr, Motomura K, et al. Peroxisome proliferators-activated receptor and hepatic stellate cell activation. J Biol Chem 2000;275:35715-22.
    • (2000) J Biol Chem , vol.275 , pp. 35715-35722
    • Miyahara, T.1    Schrum, L.2    Rippe, R.3    Xiong, S.4    Yee Jr., H.F.5    Motomura, K.6
  • 28
    • 0037016773 scopus 로고    scopus 로고
    • Ligands of peroxisome proliferator-activated receptor-γ block activation of pancreatic stellate cells
    • Masamune A, Kikuta K, Satoh M, Sakai Y, Satoh A, Shimosegawa T. Ligands of peroxisome proliferator-activated receptor-γ block activation of pancreatic stellate cells. J Biol Chem 2002;277:141-7.
    • (2002) J Biol Chem , vol.277 , pp. 141-147
    • Masamune, A.1    Kikuta, K.2    Satoh, M.3    Sakai, Y.4    Satoh, A.5    Shimosegawa, T.6
  • 30
    • 0036208794 scopus 로고    scopus 로고
    • Troglitazone stimulates pancreatic growth in normal rats
    • Jia DM, Otsuki M. Troglitazone stimulates pancreatic growth in normal rats. Pancreas 2002;24:303-12.
    • (2002) Pancreas , vol.24 , pp. 303-312
    • Jia, D.M.1    Otsuki, M.2
  • 31
    • 0023631004 scopus 로고
    • Transforming growth factor β (TGF β) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts
    • Varga J, Rosenbloom J, Jimenez SA. Transforming growth factor β (TGF β) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts. Biochem J 1987;247:597-604.
    • (1987) Biochem J , vol.247 , pp. 597-604
    • Varga, J.1    Rosenbloom, J.2    Jimenez, S.A.3
  • 32
    • 0029861965 scopus 로고    scopus 로고
    • Transcriptional regulation of the human α2(I) collagen gene: Combined action of upstream stimulatory and inhibitory cis-acting elements
    • Ihn H, Ohnishi K, Tamaki T, LeRoy EC, Trojanowska M. Transcriptional regulation of the human α2(I) collagen gene: combined action of upstream stimulatory and inhibitory cis-acting elements. J Biol Chem 1996;271:26717-23.
    • (1996) J Biol Chem , vol.271 , pp. 26717-26723
    • Ihn, H.1    Ohnishi, K.2    Tamaki, T.3    LeRoy, E.C.4    Trojanowska, M.5
  • 33
    • 0038642086 scopus 로고    scopus 로고
    • A dominant negative PPAR-γ mutant shows altered cofactor recruitment and inhibits adipogenesis in 3T3-L1 cells
    • Park Y, Freedman BD, Lee EJ, Park S, Jameson JL. A dominant negative PPAR-γ mutant shows altered cofactor recruitment and inhibits adipogenesis in 3T3-L1 cells. Diabetologia 2003;46: 365-77.
    • (2003) Diabetologia , vol.46 , pp. 365-377
    • Park, Y.1    Freedman, B.D.2    Lee, E.J.3    Park, S.4    Jameson, J.L.5
  • 34
    • 0034007387 scopus 로고    scopus 로고
    • A dominant negative peroxisome proliferators-activated receptor γ (PPAR-γ) mutant is a constitutive repressor and inhibits PPAR-γ-mediated adipogenesis
    • Gurnell M, Wentworth JM, Agostini M, Adams M, Collingwood TN, Provenzano C, et al. A dominant negative peroxisome proliferators-activated receptor γ (PPAR-γ) mutant is a constitutive repressor and inhibits PPAR-γ-mediated adipogenesis. J Biol Chem 2000;275:5754-9.
    • (2000) J Biol Chem , vol.275 , pp. 5754-5759
    • Gurnell, M.1    Wentworth, J.M.2    Agostini, M.3    Adams, M.4    Collingwood, T.N.5    Provenzano, C.6
  • 36
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type I gene
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type I gene. EMBO J 1998;17:3091-100.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 37
    • 0034255634 scopus 로고    scopus 로고
    • Modulation of endogenous SMAD expression in normal skin fibroblasts by transforming growth factor-β
    • Mori Y, Chen SJ, Varga J. Modulation of endogenous SMAD expression in normal skin fibroblasts by transforming growth factor-β. Exp Cell Res 2000;258:374-83.
    • (2000) Exp Cell Res , vol.258 , pp. 374-383
    • Mori, Y.1    Chen, S.J.2    Varga, J.3
  • 38
    • 0036185124 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ agonists: Potential use for treating chronic inflammatory diseases
    • Oates JC, Reilly CM, Crosby MB, Gilkeson GS. Peroxisome proliferator-activated receptor γ agonists: potential use for treating chronic inflammatory diseases. Arthritis Rheum. 2002;46: 598-605.
    • (2002) Arthritis Rheum , vol.46 , pp. 598-605
    • Oates, J.C.1    Reilly, C.M.2    Crosby, M.B.3    Gilkeson, G.S.4
  • 39
    • 0033595261 scopus 로고    scopus 로고
    • Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
    • Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C, et al. Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase. Nature 1999;400:378-82.
    • (1999) Nature , vol.400 , pp. 378-382
    • Huang, J.T.1    Welch, J.S.2    Ricote, M.3    Binder, C.J.4    Willson, T.M.5    Kelly, C.6
  • 41
    • 0037437371 scopus 로고    scopus 로고
    • TGF-β1-mediated fibroblast-myofibroblast terminal differentiation-the role of SMAD proteins
    • Evans RA, Tian YC, Steadman R, Phillips AO. TGF-β1-mediated fibroblast-myofibroblast terminal differentiation-the role of SMAD proteins. Exp Cell Res 2003;282:90-100.
    • (2003) Exp Cell Res , vol.282 , pp. 90-100
    • Evans, R.A.1    Tian, Y.C.2    Steadman, R.3    Phillips, A.O.4
  • 42
    • 0042831330 scopus 로고    scopus 로고
    • Smad3 mediates transforming growth factor-β-induced α-smooth muscle actin expression
    • Hu B, Wu Z, Phan SH. Smad3 mediates transforming growth factor-β-induced α-smooth muscle actin expression. Am J Respir Cell Mol Biol 2003;29:397-404.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 397-404
    • Hu, B.1    Wu, Z.2    Phan, S.H.3
  • 44
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β/Smad signaling by the interferon-γ/STAT pathway
    • Ulloa L, Doody J, Massague J. Inhibition of transforming growth factor-β/Smad signaling by the interferon-γ/STAT pathway. Nature 1999;397:710-3.
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massague, J.3
  • 45
    • 0034624057 scopus 로고    scopus 로고
    • Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-γ-induced growth inhibition and apoptosis
    • Patil S, Wildey GM, Brown TL, Choy L, Derynck R, Howe PH. Smad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-γ-induced growth inhibition and apoptosis. J Biol Chem 2000;275:38363-70.
    • (2000) J Biol Chem , vol.275 , pp. 38363-38370
    • Patil, S.1    Wildey, G.M.2    Brown, T.L.3    Choy, L.4    Derynck, R.5    Howe, P.H.6
  • 47
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 2001; 7:48-52.
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 48
    • 0035824518 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ inhibits transforming growth factor-β-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3
    • Fu M, Zhang J, Zhu X, Myles DE, Willson TM, Liu X, et al. Peroxisome proliferator-activated receptor γ inhibits transforming growth factor-β-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3. J Biol Chem 2001;276:45888-94.
    • (2001) J Biol Chem , vol.276 , pp. 45888-45894
    • Fu, M.1    Zhang, J.2    Zhu, X.3    Myles, D.E.4    Willson, T.M.5    Liu, X.6
  • 49
    • 0037444798 scopus 로고    scopus 로고
    • Early stimulation and late inhibition of peroxisome proliferators-activated receptor γ (PPAR-γ) gene expression by transforming growth factor β in human aortic smooth muscle cells: Role of early growth-response factor-1 (EGR-1), activator protein 1 (AP1) and Smads
    • Fu M, Zhang J, Lin Y, Zhu X, Zhao L, Ahmad M, et al. Early stimulation and late inhibition of peroxisome proliferators-activated receptor γ (PPAR-γ) gene expression by transforming growth factor β in human aortic smooth muscle cells: role of early growth-response factor-1 (EGR-1), activator protein 1 (AP1) and Smads. Biochem J 2003;370:1019-25.
    • (2003) Biochem J , vol.370 , pp. 1019-1025
    • Fu, M.1    Zhang, J.2    Lin, Y.3    Zhu, X.4    Zhao, L.5    Ahmad, M.6
  • 50
    • 18444412555 scopus 로고    scopus 로고
    • Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferators activated receptors by GW9662
    • Leesnitzer LM, Parks DL, Bledsoe RK, Cobb JE, Collins JL, Consler TG, et al. Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferators activated receptors by GW9662. Biochemistry 2002;41:6640-50.
    • (2002) Biochemistry , vol.41 , pp. 6640-6650
    • Leesnitzer, L.M.1    Parks, D.L.2    Bledsoe, R.K.3    Cobb, J.E.4    Collins, J.L.5    Consler, T.G.6
  • 51
    • 0036586090 scopus 로고    scopus 로고
    • Factors involved in the regulation of type I collagen gene expression: Implication in fibrosis
    • Ghosh AK. Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med 2002;227:301-14.
    • (2002) Exp Biol Med , vol.227 , pp. 301-314
    • Ghosh, A.K.1
  • 52
    • 0030870170 scopus 로고    scopus 로고
    • Oncostatin M stimulates transcription of the human α2(I) collagen gene via the Sp1/Sp3-binding site
    • Ihn H, LeRoy EC, Trojanowska M. Oncostatin M stimulates transcription of the human α2(I) collagen gene via the Sp1/Sp3-binding site. J Biol Chem 1997;272:24666-72.
    • (1997) J Biol Chem , vol.272 , pp. 24666-24672
    • Ihn, H.1    LeRoy, E.C.2    Trojanowska, M.3
  • 53
    • 0032540917 scopus 로고    scopus 로고
    • Modulation of human α1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro
    • Chen SJ, Artlett CM, Jimenez SA, Varga J. Modulation of human α1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro. Gene 1998;215:101-10.
    • (1998) Gene , vol.215 , pp. 101-110
    • Chen, S.J.1    Artlett, C.M.2    Jimenez, S.A.3    Varga, J.4
  • 54
    • 0035831503 scopus 로고    scopus 로고
    • Sp1 and Smad proteins cooperate to mediate transforming growth factor-β1-induced α2(I) collagen expression in human glomerular mesangial cells
    • Poncelet AC, Schnaper HW. Sp1 and Smad proteins cooperate to mediate transforming growth factor-β1-induced α2(I) collagen expression in human glomerular mesangial cells. J Biol Chem 2001;276:6983-92.
    • (2001) J Biol Chem , vol.276 , pp. 6983-6992
    • Poncelet, A.C.1    Schnaper, H.W.2
  • 55
    • 0030047646 scopus 로고    scopus 로고
    • An AP-1 binding sequence is essential for regulation of the human α2(I) collagen (COL1A2) promoter activity by transforming growth factor-β
    • Chung KY, Agarwal A, Uitto J, Mauviel A. An AP-1 binding sequence is essential for regulation of the human α2(I) collagen (COL1A2) promoter activity by transforming growth factor-β. J Biol Chem 1996;271:3272-8.
    • (1996) J Biol Chem , vol.271 , pp. 3272-3278
    • Chung, K.Y.1    Agarwal, A.2    Uitto, J.3    Mauviel, A.4
  • 56
    • 1842643616 scopus 로고    scopus 로고
    • Transcriptional coactivators p300/CBP and type I collagen gene expression
    • Ghosh AK, Varga J. Transcriptional coactivators p300/CBP and type I collagen gene expression. Curr Sci 2003;85:155-61.
    • (2003) Curr Sci , vol.85 , pp. 155-161
    • Ghosh, A.K.1    Varga, J.2
  • 57
    • 0032589970 scopus 로고    scopus 로고
    • TGF-β1 activates MAP kinase in human mesangial cells: A possible role in collagen expression
    • Hayashida T, Poncelet AC, Hubchak SC, Scnaper HW. TGF-β1 activates MAP kinase in human mesangial cells: a possible role in collagen expression. Kidney Int 1999;56:1710-20.
    • (1999) Kidney Int , vol.56 , pp. 1710-1720
    • Hayashida, T.1    Poncelet, A.C.2    Hubchak, S.C.3    Scnaper, H.W.4
  • 58
    • 0034991582 scopus 로고    scopus 로고
    • Stimulation of pro-α1(I) collagen by TGF-β1 in mesangial cells: Role of the p38 MAPK pathway
    • Chin BY, Mohsenin A, Li SX, Choi AM, Choi ME. Stimulation of pro-α1(I) collagen by TGF-β1 in mesangial cells: role of the p38 MAPK pathway. Am J Physiol Renal Physiol 2001;280:F495-504.
    • (2001) Am J Physiol Renal Physiol , vol.280
    • Chin, B.Y.1    Mohsenin, A.2    Li, S.X.3    Choi, A.M.4    Choi, M.E.5
  • 59
    • 0035900710 scopus 로고    scopus 로고
    • Cross-talk between transforming growth factor-β and estrogen receptor signaling through Smad3
    • Matsuda T, Yamamoto T, Muraguchi A, Saatcioglu F. Cross-talk between transforming growth factor-β and estrogen receptor signaling through Smad3. J Biol Chem 2001;276:42908-14.
    • (2001) J Biol Chem , vol.276 , pp. 42908-42914
    • Matsuda, T.1    Yamamoto, T.2    Muraguchi, A.3    Saatcioglu, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.