메뉴 건너뛰기




Volumn 26, Issue 15, 2007, Pages 3686-3698

Deregulation of tumor angiogenesis and blockade of tumor growth in PPARβ-deficient mice

Author keywords

Hyperplasia; p57KIP2 Cdkn1c; Peroxisome proliferator activated receptor ; Tumor angiogenesis; Tumor growth

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1C; MATRIGEL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; TEMSIROLIMUS;

EID: 34547791776     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601803     Document Type: Article
Times cited : (92)

References (47)
  • 1
    • 0037360164 scopus 로고    scopus 로고
    • Thrombospondins 1 and 2 function as inhibitors of angiogenesis
    • Armstrong LC, Bornstein P (2003) Thrombospondins 1 and 2 function as inhibitors of angiogenesis. Matrix Biol 22: 63-71
    • (2003) Matrix Biol , vol.22 , pp. 63-71
    • Armstrong, L.C.1    Bornstein, P.2
  • 3
    • 33644645013 scopus 로고    scopus 로고
    • PPAR delta: A dagger in the heart of the metabolic syndrome
    • Barish GD, Narkar VA, Evans RM (2006) PPAR delta: a dagger in the heart of the metabolic syndrome. J Clin Invest 116: 590-597
    • (2006) J Clin Invest , vol.116 , pp. 590-597
    • Barish, G.D.1    Narkar, V.A.2    Evans, R.M.3
  • 5
    • 34147146967 scopus 로고    scopus 로고
    • Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes
    • Burdick AD, Bility MT, Girroir EE, Billin AN, Willson TM, Gonzalez FJ, Peters JM (2007) Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes. Cell Signal 19: 1163-1171
    • (2007) Cell Signal , vol.19 , pp. 1163-1171
    • Burdick, A.D.1    Bility, M.T.2    Girroir, E.E.3    Billin, A.N.4    Willson, T.M.5    Gonzalez, F.J.6    Peters, J.M.7
  • 6
    • 26244443261 scopus 로고    scopus 로고
    • The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation
    • Burdick AD, Kim DJ, Peraza MA, Gonzalez FJ, Peters JM (2006) The role of peroxisome proliferator-activated receptor-beta/delta in epithelial cell growth and differentiation. Cell Signal 18: 9-20
    • (2006) Cell Signal , vol.18 , pp. 9-20
    • Burdick, A.D.1    Kim, D.J.2    Peraza, M.A.3    Gonzalez, F.J.4    Peters, J.M.5
  • 7
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P (2000) Mechanisms of angiogenesis and arteriogenesis. Nat Med 6: 389-395
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 8
    • 3142652478 scopus 로고    scopus 로고
    • Lumen digestion' technique for isolation of aortic endothelial cells from heme oxygenase-1 knockout mice
    • Chen S, Sega M, Agarwal A (2004) 'Lumen digestion' technique for isolation of aortic endothelial cells from heme oxygenase-1 knockout mice. Biotechniques 37: 84-89
    • (2004) Biotechniques , vol.37 , pp. 84-89
    • Chen, S.1    Sega, M.2    Agarwal, A.3
  • 9
    • 0037626078 scopus 로고    scopus 로고
    • Functional tumor imaging with dynamic contrast-enhanced magnetic resonance imaging
    • Choyke PL, Dwyer AJ, Knopp MV (2003) Functional tumor imaging with dynamic contrast-enhanced magnetic resonance imaging. J Magn Reson Imaging 17: 509-520
    • (2003) J Magn Reson Imaging , vol.17 , pp. 509-520
    • Choyke, P.L.1    Dwyer, A.J.2    Knopp, M.V.3
  • 10
    • 33645863768 scopus 로고    scopus 로고
    • Transcriptional regulation of metabolism
    • Desvergne B, Michalik L, Wahli W (2006) Transcriptional regulation of metabolism. Physiol Rev 86: 465-514
    • (2006) Physiol Rev , vol.86 , pp. 465-514
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 11
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W (2006) From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 45: 120-159
    • (2006) Prog Lipid Res , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 12
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman J (2002) Role of angiogenesis in tumor growth and metastasis. Semin Oncol 29: 15-18
    • (2002) Semin Oncol , vol.29 , pp. 15-18
    • Folkman, J.1
  • 13
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman BM, Chen J, Evans RM (1997) Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci USA 94: 4312-4317
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 16
    • 1942470331 scopus 로고    scopus 로고
    • Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
    • Gupta RA, Wang D, Katkuri S, Wang H, Dey SK, DuBois RN (2004) Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth. Nat Med 10: 245-247
    • (2004) Nat Med , vol.10 , pp. 245-247
    • Gupta, R.A.1    Wang, D.2    Katkuri, S.3    Wang, H.4    Dey, S.K.5    DuBois, R.N.6
  • 19
  • 21
    • 15744366162 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by downregulation of kinase activity
    • Kim DJ, Murray IA, Burns AM, Gonzalez FJ, Perdew GH, Peters JM (2005) Peroxisome proliferator-activated receptor-beta/delta inhibits epidermal cell proliferation by downregulation of kinase activity. J Biol Chem 280: 9519-9527
    • (2005) J Biol Chem , vol.280 , pp. 9519-9527
    • Kim, D.J.1    Murray, I.A.2    Burns, A.M.3    Gonzalez, F.J.4    Perdew, G.H.5    Peters, J.M.6
  • 22
    • 34547112065 scopus 로고    scopus 로고
    • Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle
    • Kitz Kramer D, Al-Khalili L, Guigas B, Leng Y, Garcia-Roves PM, Krook A (2007) Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle. J Biol Chem 280: 19313-19320
    • (2007) J Biol Chem , vol.280 , pp. 19313-19320
    • Kitz Kramer, D.1    Al-Khalili, L.2    Guigas, B.3    Leng, Y.4    Garcia-Roves, P.M.5    Krook, A.6
  • 23
    • 5444242184 scopus 로고    scopus 로고
    • Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
    • Krebs LT, Shutter JR, Tanigaki K, Honjo T, Stark KL, Gridley T (2004) Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev 18: 2469-2473
    • (2004) Genes Dev , vol.18 , pp. 2469-2473
    • Krebs, L.T.1    Shutter, J.R.2    Tanigaki, K.3    Honjo, T.4    Stark, K.L.5    Gridley, T.6
  • 24
    • 33847399658 scopus 로고    scopus 로고
    • Differential tumor suppressor properties and transforming growth factor-beta responsiveness of p57KIP2 in leukemia cells with aberrant p57KIP2 promoter DNA methylation
    • Kuang SQ, Ling X, Sanchez-Gonzalez B, Yang H, Andreeff M, Garcia-Manero G (2007) Differential tumor suppressor properties and transforming growth factor-beta responsiveness of p57KIP2 in leukemia cells with aberrant p57KIP2 promoter DNA methylation. Oncogene 26: 1439-1448
    • (2007) Oncogene , vol.26 , pp. 1439-1448
    • Kuang, S.Q.1    Ling, X.2    Sanchez-Gonzalez, B.3    Yang, H.4    Andreeff, M.5    Garcia-Manero, G.6
  • 26
    • 0028988158 scopus 로고
    • Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • Lee MH, Reynisdottir I, Massague J (1995) Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9: 639-649
    • (1995) Genes Dev , vol.9 , pp. 639-649
    • Lee, M.H.1    Reynisdottir, I.2    Massague, J.3
  • 27
    • 14244263841 scopus 로고    scopus 로고
    • Angiogenic synergy of bFGF and VEGF is antagonized by Angiopoietin-2 in a modified in vivo Matrigel assay
    • Ley CD, Olsen MW, Lund EL, Kristjansen PE (2004) Angiogenic synergy of bFGF and VEGF is antagonized by Angiopoietin-2 in a modified in vivo Matrigel assay. Microvasc Res 68: 161-168
    • (2004) Microvasc Res , vol.68 , pp. 161-168
    • Ley, C.D.1    Olsen, M.W.2    Lund, E.L.3    Kristjansen, P.E.4
  • 28
    • 17344363706 scopus 로고    scopus 로고
    • Transient expression of SV 40 large T antigen by Cre/LoxP-mediated site-specific deletion in primary human tumor cells
    • Li LP, Schlag PM, Blankenstein T (1997) Transient expression of SV 40 large T antigen by Cre/LoxP-mediated site-specific deletion in primary human tumor cells. Hum Gene Ther 8: 1695-1700
    • (1997) Hum Gene Ther , vol.8 , pp. 1695-1700
    • Li, L.P.1    Schlag, P.M.2    Blankenstein, T.3
  • 32
    • 33645802802 scopus 로고    scopus 로고
    • Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta
    • Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B (2006) Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol 26: 3266-3281
    • (2006) Mol Cell Biol , vol.26 , pp. 3266-3281
    • Nadra, K.1    Anghel, S.I.2    Joye, E.3    Tan, N.S.4    Basu-Modak, S.5    Trono, D.6    Wahli, W.7    Desvergne, B.8
  • 34
    • 0035956850 scopus 로고    scopus 로고
    • Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells
    • Park BH, Vogelstein B, Kinzler KW (2001) Genetic disruption of PPARdelta decreases the tumorigenicity of human colon cancer cells. Proc Natl Acad Sci USA 98: 2598-2603
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2598-2603
    • Park, B.H.1    Vogelstein, B.2    Kinzler, K.W.3
  • 35
    • 33645112691 scopus 로고    scopus 로고
    • The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR)
    • Peraza MA, Burdick AD, Marin HE, Gonzalez FJ, Peters JM (2006) The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR). Toxicol Sci 90: 269-295
    • (2006) Toxicol Sci , vol.90 , pp. 269-295
    • Peraza, M.A.1    Burdick, A.D.2    Marin, H.E.3    Gonzalez, F.J.4    Peters, J.M.5
  • 36
    • 0033625677 scopus 로고    scopus 로고
    • Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor beta(delta)
    • Peters JM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ (2000) Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator- activated receptor beta(delta). Mol Cell Biol 20: 5119-5128
    • (2000) Mol Cell Biol , vol.20 , pp. 5119-5128
    • Peters, J.M.1    Lee, S.S.2    Li, W.3    Ward, J.M.4    Gavrilova, O.5    Everett, C.6    Reitman, M.L.7    Hudson, L.D.8    Gonzalez, F.J.9
  • 39
    • 17144379334 scopus 로고    scopus 로고
    • Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption
    • Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS (2005) Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature 434: 786-792
    • (2005) Nature , vol.434 , pp. 786-792
    • Saadoun, S.1    Papadopoulos, M.C.2    Hara-Chikuma, M.3    Verkman, A.S.4
  • 40
    • 0033237650 scopus 로고    scopus 로고
    • p57Kip2, a glucocorticoid-induced inhibitor of cell cycle progression in HeLa cells
    • Samuelsson MK, Pazirandeh A, Davani B, Okret S (1999) p57Kip2, a glucocorticoid-induced inhibitor of cell cycle progression in HeLa cells. Mol Endocrinol 13: 1811-1822
    • (1999) Mol Endocrinol , vol.13 , pp. 1811-1822
    • Samuelsson, M.K.1    Pazirandeh, A.2    Davani, B.3    Okret, S.4
  • 41
    • 0037013201 scopus 로고    scopus 로고
    • Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands
    • Sato O, Kuriki C, Fukui Y, Motojima K (2002) Dual promoter structure of mouse and human fatty acid translocase/CD36 genes and unique transcriptional activation by peroxisome proliferator-activated receptor alpha and gamma ligands. J Biol Chem 277: 15703-15711
    • (2002) J Biol Chem , vol.277 , pp. 15703-15711
    • Sato, O.1    Kuriki, C.2    Fukui, Y.3    Motojima, K.4
  • 44
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM (1998) PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93: 241-252
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.