-
1
-
-
0031057517
-
Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
-
Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK: Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J Biol Chem 272:5128-5132, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 5128-5132
-
-
Adams, M.1
Reginato, M.J.2
Shao, D.3
Lazar, M.A.4
Chatterjee, V.K.5
-
2
-
-
0031963751
-
Pro-inflammatory signaling: Last pieces in the NF-κB puzzle?
-
Baeuerle PA: Pro-inflammatory signaling: Last pieces in the NF-κB puzzle? Curr Biol 8:R19-R22, 1998
-
(1998)
Curr Biol
, vol.8
-
-
Baeuerle, P.A.1
-
3
-
-
0033933236
-
Deactivarion of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth
-
Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP: Deactivarion of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth. J Clin Invest 105:1723-1730, 2000
-
(2000)
J Clin Invest
, vol.105
, pp. 1723-1730
-
-
Barger, P.M.1
Brandt, J.M.2
Leone, T.C.3
Weinheimer, C.J.4
Kelly, D.P.5
-
4
-
-
0030615201
-
Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M: Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071, 1997
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
6
-
-
0033539885
-
Increased expression of p50-NF-κB and constitutive activation of NF-κB transcription factors during mouse skin carcinogenesis
-
Budunova IV, Perez P, Vaden VR, Spiegelman VS, Slaga TJ, Jorcano JL: Increased expression of p50-NF-κB and constitutive activation of NF-κB transcription factors during mouse skin carcinogenesis. Oncogene 18:7423-7431, 1999
-
(1999)
Oncogene
, vol.18
, pp. 7423-7431
-
-
Budunova, I.V.1
Perez, P.2
Vaden, V.R.3
Spiegelman, V.S.4
Slaga, T.J.5
Jorcano, J.L.6
-
7
-
-
0030964085
-
Regulation of peroxisome proliferator-activatcd receptor γ activity by mitogen-activated protein kinase
-
Camp HS, Tafuri SR: Regulation of peroxisome proliferator-activatcd receptor γ activity by mitogen-activated protein kinase. J Biol Chem 272:10811-10816, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 10811-10816
-
-
Camp, H.S.1
Tafuri, S.R.2
-
8
-
-
0032894240
-
c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-γ1 and negatively regulates its transcriptional activity
-
Camp HS, Tafuri SR, Leff T: c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-γ1 and negatively regulates its transcriptional activity. Endocrinol 140:392-397, 1999
-
(1999)
Endocrinol
, vol.140
, pp. 392-397
-
-
Camp, H.S.1
Tafuri, S.R.2
Leff, T.3
-
9
-
-
0021069607
-
The identification of hydroxy fatty acids in psoriatic skin
-
Camp RD, Mallet AI, Woollard PM, Brain SD, Black AK, Greaves MW: The identification of hydroxy fatty acids in psoriatic skin. Prostaglandins 26:431-447, 1983
-
(1983)
Prostaglandins
, vol.26
, pp. 431-447
-
-
Camp, R.D.1
Mallet, A.I.2
Woollard, P.M.3
Brain, S.D.4
Black, A.K.5
Greaves, M.W.6
-
10
-
-
0032475922
-
Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages
-
Chinetti G, Griglio S, Antonucci M, et al. Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages. J Biol Chem 273:25573-25580, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 25573-25580
-
-
Chinetti, G.1
Griglio, S.2
Antonucci, M.3
-
11
-
-
0034693323
-
Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-γ and nuclear factor-κB
-
Chung SW, Kang BY, Kim SH, Pak YK, Cho D, Trinchieri G, Kim TS: Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-γ and nuclear factor-κB. J Biol Chem 275: 32681-32687, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 32681-32687
-
-
Chung, S.W.1
Kang, B.Y.2
Kim, S.H.3
Pak, Y.K.4
Cho, D.5
Trinchieri, G.6
Kim, T.S.7
-
12
-
-
0033527569
-
Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1
-
Delerive P, De B, Besnard S, et al: Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1. J Biol Chem 274:32048-32054, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 32048-32054
-
-
Delerive, P.1
De, B.2
Besnard, S.3
-
13
-
-
0034711185
-
Induction of IκBα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators
-
Delerive P, Gervois P, Fruchart JC, Staels B: Induction of IκBα expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-α activators. J Biol Chem 275:36703-36707, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 36703-36707
-
-
Delerive, P.1
Gervois, P.2
Fruchart, J.C.3
Staels, B.4
-
14
-
-
0036255486
-
DNA binding-independent induction of IκBα gene transcription by PPARα
-
Delerive P, De Bosscher K, Vanden Berghe W, Fruchart JC, Haegeman G, Staels B: DNA binding-independent induction of IκBα gene transcription by PPARα. Mol Endocrinol 16:1029-1039, 2002
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1029-1039
-
-
Delerive, P.1
De Bosscher, K.2
Vanden Berghe, W.3
Fruchart, J.C.4
Haegeman, G.5
Staels, B.6
-
15
-
-
0029661982
-
The PPARα-leukotriene B4 pathway to inflammation control
-
Devchand PR, Keller H, Peters JM, Vaquez M, Gonzalez FJ, Wahli W: The PPARα-leukotriene B4 pathway to inflammation control. Nature 384:39-43, 1996
-
(1996)
Nature
, vol.384
, pp. 39-43
-
-
Devchand, P.R.1
Keller, H.2
Peters, J.M.3
Vaquez, M.4
Gonzalez, F.J.5
Wahli, W.6
-
16
-
-
0036771764
-
Antiapoptotic role of PPARβ in keratinocytes via transcriptional control of the Akt1 signaling pathway
-
Di-Poï N, Tan MS, Michalik L, Wahli W, Desvergne B: Antiapoptotic role of PPARβ in keratinocytes via transcriptional control of the Akt1 signaling pathway. Mol Cell 10:721-733, 2002
-
(2002)
Mol Cell
, vol.10
, pp. 721-733
-
-
Di-Poï, N.1
Tan, M.S.2
Michalik, L.3
Wahli, W.4
Desvergne, B.5
-
17
-
-
0034030527
-
Troglitazone improves psoriasis and normalizes models of proliferative skin disease: Ligands for peroxisome proliferator-activated receptor-γ inhibit keratinocyte proliferation
-
Ellis CN, Varani J, Fisher GJ, et al: Troglitazone improves psoriasis and normalizes models of proliferative skin disease: Ligands for peroxisome proliferator-activated receptor-γ inhibit keratinocyte proliferation. Arch Dermatol 136:609-616, 2000
-
(2000)
Arch Dermatol
, vol.136
, pp. 609-616
-
-
Ellis, C.N.1
Varani, J.2
Fisher, G.J.3
-
18
-
-
0024379529
-
Eicosanoids in acute and chronic psoriatic lesions: Leukotriene B4, but not 12-hydroxy-cicosatetraenoic acid, is present in biologically active amounts in acute guttate lesions
-
Fogh K, Herlin T, Kragballe K: Eicosanoids in acute and chronic psoriatic lesions: Leukotriene B4, but not 12-hydroxy-cicosatetraenoic acid, is present in biologically active amounts in acute guttate lesions. J Invest Dermatol 92:837-841, 1989
-
(1989)
J Invest Dermatol
, vol.92
, pp. 837-841
-
-
Fogh, K.1
Herlin, T.2
Kragballe, K.3
-
19
-
-
0028972025
-
15-Deoxy-δ12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
-
Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM: 15-Deoxy-δ12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell 83:803-812, 1995
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
20
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty-acids, and eicosanoids are ligands for peroxisome proliferator-activated receptor-α and receptor-δ
-
Forman BM, Chen J, Evans RM: Hypolipidemic drugs, polyunsaturated fatty-acids, and eicosanoids are ligands for peroxisome proliferator-activated receptor-α and receptor-δ. Proc Natl Acad Sci USA 94:4312-4317, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
21
-
-
0036245242
-
Getting under the skin of epidermal morphogenesis
-
Fuchs E, Raghavan S: Getting under the skin of epidermal morphogenesis. Nat Rev Genet 3:199-209, 2002
-
(2002)
Nat Rev Genet
, vol.3
, pp. 199-209
-
-
Fuchs, E.1
Raghavan, S.2
-
22
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh S, Karin M: Missing pieces in the NF-κB puzzle. Cell 109:S81-S96, 2002
-
(2002)
Cell
, vol.109
-
-
Ghosh, S.1
Karin, M.2
-
23
-
-
0001268667
-
Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2α in epidermis of psoriasis
-
Hammarstrom S, Hamberg M, Samuelsson B, Duell EA, Stawiski M, Voorhees JJ: Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2α in epidermis of psoriasis. Proc Natl Acad Sci USA 72:5130-5134, 1975
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 5130-5134
-
-
Hammarstrom, S.1
Hamberg, M.2
Samuelsson, B.3
Duell, E.A.4
Stawiski, M.5
Voorhees, J.J.6
-
24
-
-
0030835838
-
Activators of the nuclear hormone receptors PPARα and FXR accelerate the development of the fetal epidermal permeability barrier
-
Hanley K, Jiang Y, Crumrine D, et al: Activators of the nuclear hormone receptors PPARα and FXR accelerate the development of the fetal epidermal permeability barrier. J Clin Invest 100:705-712, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 705-712
-
-
Hanley, K.1
Jiang, Y.2
Crumrine, D.3
-
25
-
-
0031945627
-
Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARα
-
Hanley K, Jiang Y, He SS, et al: Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARα. J Invest Dermatol 110:368-375, 1998
-
(1998)
J Invest Dermatol
, vol.110
, pp. 368-375
-
-
Hanley, K.1
Jiang, Y.2
He, S.S.3
-
26
-
-
0032725472
-
Fetal epidermal differentiation and barrier development in vivo is accelerated by nuclear hormone receptor activators
-
Hanley K, Komuves LG, Bass NM, et al. Fetal epidermal differentiation and barrier development in vivo is accelerated by nuclear hormone receptor activators. J Invest Dermatol 113:788-795, 1999
-
(1999)
J Invest Dermatol
, vol.113
, pp. 788-795
-
-
Hanley, K.1
Komuves, L.G.2
Bass, N.M.3
-
27
-
-
0040952982
-
Farnesol stimulates differentiation in epidermal keratinocytes via PPARα
-
Hanley K, Komuves LG, Ng DC, et al: Farnesol stimulates differentiation in epidermal keratinocytes via PPARα. J Biol Chem 275:11484-11491, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 11484-11491
-
-
Hanley, K.1
Komuves, L.G.2
Ng, D.C.3
-
28
-
-
0035793577
-
Peroxisome proliferator-activated receptor δ (PPARδ) -mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling
-
Hansen JB, Zhang H, Rasmussen TH, Petersen RK, Flindt EN, Kristiansen K: Peroxisome proliferator-activated receptor δ (PPARδ) -mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling. J Biol Chem 276:3175-3182, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 3175-3182
-
-
Hansen, J.B.1
Zhang, H.2
Rasmussen, T.H.3
Petersen, R.K.4
Flindt, E.N.5
Kristiansen, K.6
-
29
-
-
0033615352
-
PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs
-
He TC, Chan TA, Vogelstein B, Kinzler KW: PPARδ is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99:335-345, 1999
-
(1999)
Cell
, vol.99
, pp. 335-345
-
-
He, T.C.1
Chan, T.A.2
Vogelstein, B.3
Kinzler, K.W.4
-
30
-
-
0033565763
-
Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling
-
van Hogerlinden M, Rozell BL, Ahrlund-Richter L, Toftgard R: Squamous cell carcinomas and increased apoptosis in skin with inhibited Rel/nuclear factor-κB signaling. Cancer Res 59:3299-3303, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 3299-3303
-
-
Van Hogerlinden, M.1
Rozell, B.L.2
Ahrlund-Richter, L.3
Toftgard, R.4
-
31
-
-
0035860789
-
15-Lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor γ via the MAPK signaling pathway
-
Hsi LC, Wilson L, Nixon J, Eling TE: 15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor γ via the MAPK signaling pathway. J Biol Chem 276:34545-34552, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 34545-34552
-
-
Hsi, L.C.1
Wilson, L.2
Nixon, J.3
Eling, T.E.4
-
32
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
-
Hu E, Kim JB, Sarraf P, Spiegelman BM: Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science 274:2100-2103, 1996
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
33
-
-
0033537767
-
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
-
Hu Y, Baud V, Delhase M, et al: Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase. Science 284:316-320, 1999
-
(1999)
Science
, vol.284
, pp. 316-320
-
-
Hu, Y.1
Baud, V.2
Delhase, M.3
-
34
-
-
0035809983
-
IKKα controls formation of the epidermis independently of NF-κB
-
Hu Y, Baud V, Oga T, Kim KI, Yoshida K, Karin M: IKKα controls formation of the epidermis independently of NF-κB. Nature 410:710-714, 2001
-
(2001)
Nature
, vol.410
, pp. 710-714
-
-
Hu, Y.1
Baud, V.2
Oga, T.3
Kim, K.I.4
Yoshida, K.5
Karin, M.6
-
35
-
-
0027945530
-
Effects of vitamin D metabolites on proliferation and differentiation of cultured human epidermal keratinocytes grown in serum-free or defined culture medium
-
Itin PH, Pittelkow MR, Kumar R: Effects of vitamin D metabolites on proliferation and differentiation of cultured human epidermal keratinocytes grown in serum-free or defined culture medium. Endocrinol 135:1793-1798, 1994
-
(1994)
Endocrinol
, vol.135
, pp. 1793-1798
-
-
Itin, P.H.1
Pittelkow, M.R.2
Kumar, R.3
-
36
-
-
0034663467
-
Peroxisome-proliferator-activated receptor δ mediates the effects of long-chain fatty acids on post-confluent cell proliferation
-
Jehl P, Bastie C, Gillot I, Luquet S, Grimaldi PA: Peroxisome- proliferator-activated receptor δ mediates the effects of long-chain fatty acids on post-confluent cell proliferation. Biochem J 350 Part 1:93-98, 2000
-
(2000)
Biochem J
, vol.350
, Issue.1 PART
, pp. 93-98
-
-
Jehl, P.1
Bastie, C.2
Gillot, I.3
Luquet, S.4
Grimaldi, P.A.5
-
37
-
-
0031888958
-
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B: PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82-86, 1998
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
38
-
-
0033625342
-
1α,25-dihydroxyvitamin D3 induced differentiation of cultured human keratinocytes is accompanied by a PKC-independent regulation of AP-1 DNA binding activity
-
Johansen C, Iversen L, Ryborg A, Kragballe K: 1α,25- dihydroxyvitamin D3 induced differentiation of cultured human keratinocytes is accompanied by a PKC-independent regulation of AP-1 DNA binding activity. J Invest Dermatol 114: 1174-1179, 2000
-
(2000)
J Invest Dermatol
, vol.114
, pp. 1174-1179
-
-
Johansen, C.1
Iversen, L.2
Ryborg, A.3
Kragballe, K.4
-
39
-
-
0033537827
-
Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor α by phosphorylation of a ligand-independent trans-activating domain
-
Juge-Aubry CE, Hammar E, Siegrist-Kaiser C, et al: Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor α by phosphorylation of a ligand-independent trans-activating domain. J Biol Chem 274:10505-10510, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 10505-10510
-
-
Juge-Aubry, C.E.1
Hammar, E.2
Siegrist-Kaiser, C.3
-
40
-
-
0034729346
-
It's got you covered. NF-κB in the epidermis
-
Kaufman CK, Fuchs E: It's got you covered. NF-κB in the epidermis. J Cell Biol 149:999-1004, 2000
-
(2000)
J Cell Biol
, vol.149
, pp. 999-1004
-
-
Kaufman, C.K.1
Fuchs, E.2
-
41
-
-
0029664657
-
IκBα deficiency results in a sustained NF-κB response and severe widespread dermatitis in mice
-
Klement JF, Rice NR, Car BD, et al: IκBα deficiency results in a sustained NF-κB response and severe widespread dermatitis in mice. Mol Cell Biol 16:2341-2349, 1996
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2341-2349
-
-
Klement, J.F.1
Rice, N.R.2
Car, B.D.3
-
42
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
-
Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, Lehmann JM: A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83:813-819, 1995
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehmann, J.M.6
-
43
-
-
0006132932
-
Fatty-acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptor-α and receptor-γ
-
Kliewer SA, Sundseth SS, Jones SA, et al: Fatty-acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptor-α and receptor-γ. Proc Natl Acad Sci USA 94:4318-4323, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
Sundseth, S.S.2
Jones, S.A.3
-
44
-
-
0031657806
-
Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development
-
Komuves LG, Hanley K, Jiang Y, Elias PM, Williams ML, Feingold KR: Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development. J Invest Dermatol 111:429-433, 1998
-
(1998)
J Invest Dermatol
, vol.111
, pp. 429-433
-
-
Komuves, L.G.1
Hanley, K.2
Jiang, Y.3
Elias, P.M.4
Williams, M.L.5
Feingold, K.R.6
-
45
-
-
0033624558
-
Stimulation of PPARα promotes epidermal keratinocyte differentiation in vivo
-
Komuves LG, Hanley K, Lefebvre AM, et al: Stimulation of PPARα promotes epidermal keratinocyte differentiation in vivo. J Invest Dermatol 115:353-360, 2000a
-
(2000)
J Invest Dermatol
, vol.115
, pp. 353-360
-
-
Komuves, L.G.1
Hanley, K.2
Lefebvre, A.M.3
-
46
-
-
0033832034
-
Keratinocyte differentiation in hyperproliferative epidermis. Topical application of PPARα activators restores tissue homeostasis
-
Komuves LG, Hanley K, Man MQ, Elias PM, Williams ML, Feingold KR: Keratinocyte differentiation in hyperproliferative epidermis. Topical application of PPARα activators restores tissue homeostasis. J Invest Dermatol 115:361-367, 2000b
-
(2000)
J Invest Dermatol
, vol.115
, pp. 361-367
-
-
Komuves, L.G.1
Hanley, K.2
Man, M.Q.3
Elias, P.M.4
Williams, M.L.5
Feingold, K.R.6
-
47
-
-
0022504616
-
Increased aggregation and arachidonic acid transformation by psoriatic platelets: Evidence that platelet-derived 12-hydroxy-eicosatetraenoic acid increases keratinocyte DNA synthesis in vitro
-
Kragballe K, Fallon JD: Increased aggregation and arachidonic acid transformation by psoriatic platelets: Evidence that platelet-derived 12-hydroxy-eicosatetraenoic acid increases keratinocyte DNA synthesis in vitro. Arch Dermatol Res 278:449-453, 1986
-
(1986)
Arch Dermatol Res
, vol.278
, pp. 449-453
-
-
Kragballe, K.1
Fallon, J.D.2
-
48
-
-
0030985318
-
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
-
Krey G, Braissant O, L'Horset F, Kalkhoven E, Perroud M, Parker MG, Wahli W: Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol Endocrinol 11:779-791, 1997
-
(1997)
Mol Endocrinol
, vol.11
, pp. 779-791
-
-
Krey, G.1
Braissant, O.2
L'Horset, F.3
Kalkhoven, E.4
Perroud, M.5
Parker, M.G.6
Wahli, W.7
-
49
-
-
0033564589
-
Microaffinity columns for analysis of protein-protein interactions
-
Kussmann-Gerber S, Kratchmarova I, Mandrup S, Kristiansen K: Microaffinity columns for analysis of protein-protein interactions. Anal Biochem 271:102-105, 1999
-
(1999)
Anal Biochem
, vol.271
, pp. 102-105
-
-
Kussmann-Gerber, S.1
Kratchmarova, I.2
Mandrup, S.3
Kristiansen, K.4
-
50
-
-
0034609819
-
Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis
-
Li M, Indra AK, Warot X, et al: Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis. Nature 407:633-636, 2000a
-
(2000)
Nature
, vol.407
, pp. 633-636
-
-
Li, M.1
Indra, A.K.2
Warot, X.3
-
51
-
-
0034121698
-
Peroxisome proliferator-activated receptor γ-dependent repression of the inducible nitric oxide synthase gene
-
Li M, Pascual G, Glass CK: Peroxisome proliferator-activated receptor γ-dependent repression of the inducible nitric oxide synthase gene. Mol Cell Biol 20: 4699-4707, 2000b
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4699-4707
-
-
Li, M.1
Pascual, G.2
Glass, C.K.3
-
52
-
-
0033563227
-
IKK1-deficient mice exhibit abnormal development of skin and skeleton
-
Li Q, Lu Q, Hwang JY, Buscher D, Lee KF, Izpisua-Belmonte JC, Verma IM: IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev 13:1322-1328, 1999
-
(1999)
Genes Dev
, vol.13
, pp. 1322-1328
-
-
Li, Q.1
Lu, Q.2
Hwang, J.Y.3
Buscher, D.4
Lee, K.F.5
Izpisua-Belmonte, J.C.6
Verma, I.M.7
-
53
-
-
0026042087
-
Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly upregulated in psoriatic skin
-
Madsen P, Rasmussen HH, Leffers H, et al: Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly upregulated in psoriatic skin. J Invest Dermatol 97:701-712, 1991
-
(1991)
J Invest Dermatol
, vol.97
, pp. 701-712
-
-
Madsen, P.1
Rasmussen, H.H.2
Leffers, H.3
-
54
-
-
0033634663
-
Female mice heterozygous for IKKγ/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
-
Makris C, Godfrey VL, Krahn-Senftleben G, et al: Female mice heterozygous for IKKγ/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol Cell 5:969-979, 2000
-
(2000)
Mol Cell
, vol.5
, pp. 969-979
-
-
Makris, C.1
Godfrey, V.L.2
Krahn-Senftleben, G.3
-
55
-
-
0031973989
-
Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: Modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE)
-
Mani I, Iversen L, Ziboh VA: Upregulation of nuclear PKC and MAP-kinase during hyperproliferation of guinea pig epidermis: Modulation by 13-(S)-hydroxyoctadecadienoic acid (13-HODE). Cell Signal 10:143-149, 1998
-
(1998)
Cell Signal
, vol.10
, pp. 143-149
-
-
Mani, I.1
Iversen, L.2
Ziboh, V.A.3
-
56
-
-
0033601824
-
Correlation between expression of peroxisome proliferator-activated receptor β and squamous differentiation in epidermal and tracheobronchial epithelial cells
-
Matsuura H, Adachi H, Smart RC, Xu X, Arata J, Jetten AM: Correlation between expression of peroxisome proliferator-activated receptor β and squamous differentiation in epidermal and tracheobronchial epithelial cells. Mol Cell Endocrinol 147:85-92, 1999
-
(1999)
Mol Cell Endocrinol
, vol.147
, pp. 85-92
-
-
Matsuura, H.1
Adachi, H.2
Smart, R.C.3
Xu, X.4
Arata, J.5
Jetten, A.M.6
-
57
-
-
0035921419
-
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR) α and PPAR β mutant mice
-
Michalik L, Desvergne B, Tan NS, et al: Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR) α and PPAR β mutant mice. J Cell Biol 154:799-814, 2001
-
(2001)
J Cell Biol
, vol.154
, pp. 799-814
-
-
Michalik, L.1
Desvergne, B.2
Tan, N.S.3
-
58
-
-
0037142027
-
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
-
Pasparakis M, Courtois G, Hafner M, et al: TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2. Nature 417:861-866, 2002
-
(2002)
Nature
, vol.417
, pp. 861-866
-
-
Pasparakis, M.1
Courtois, G.2
Hafner, M.3
-
59
-
-
0026285810
-
Epidermal vitamin D metabolism, function, and regulation
-
Pillai S, Bikle DD: Epidermal vitamin D metabolism, function, and regulation. Adv Lipid Res 24:321-341, 1991
-
(1991)
Adv Lipid Res
, vol.24
, pp. 321-341
-
-
Pillai, S.1
Bikle, D.D.2
-
60
-
-
0032484123
-
Peroxisome proliterator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging
-
Poynter ME, Daynes RA: Peroxisome proliterator-activated receptor α activation modulates cellular redox status, represses nuclear factor-κB signaling, and reduces inflammatory cytokine production in aging. J Biol Chem 273: 32833-32841, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 32833-32841
-
-
Poynter, M.E.1
Daynes, R.A.2
-
61
-
-
0034740726
-
Role of NF-κB activity in apoptotic response of keratinocytes mediated by interteron-γ, tumor necrosis factor-α, and tumor-necrosis-factor-related apoptosis-inducing ligand
-
Qin JZ, Bacon P, Chaturvedi V, Nickoloff BJ: Role of NF-κB activity in apoptotic response of keratinocytes mediated by interteron-γ, tumor necrosis factor-α, and tumor-necrosis-factor-related apoptosis-inducing ligand. J Invest Dermatol 117:898-907, 2001
-
(2001)
J Invest Dermatol
, vol.117
, pp. 898-907
-
-
Qin, J.Z.1
Bacon, P.2
Chaturvedi, V.3
Nickoloff, B.J.4
-
62
-
-
0031886864
-
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
-
Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK: The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391:79-82, 1998
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
63
-
-
0032448111
-
Differential expression of peroxisome proliferator-activated receptor subtypes during the differentiation of human keratinocytes
-
Rivier M, Safonova I, Lebrun P, Griffiths CE, Ailhaud G, Michel S: Differential expression of peroxisome proliferator-activated receptor subtypes during the differentiation of human keratinocytes. J Invest Dermatol 111:1116-1121, 1998
-
(1998)
J Invest Dermatol
, vol.111
, pp. 1116-1121
-
-
Rivier, M.1
Safonova, I.2
Lebrun, P.3
Griffiths, C.E.4
Ailhaud, G.5
Michel, S.6
-
64
-
-
0034004910
-
Peroxisome proliferator-activated receptor-α enhances lipid metabolism in a skin equivalent model
-
Rivier M, Castiel I, Safonova I, Ailhaud G, Michel S: Peroxisome proliferator-activated receptor-α enhances lipid metabolism in a skin equivalent model. J Invest Dermatol 114:681-687, 2000
-
(2000)
J Invest Dermatol
, vol.114
, pp. 681-687
-
-
Rivier, M.1
Castiel, I.2
Safonova, I.3
Ailhaud, G.4
Michel, S.5
-
65
-
-
0032589462
-
IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain
-
Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W: IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain. J Biol Chem 274:30353-30356, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 30353-30356
-
-
Sakurai, H.1
Chiba, H.2
Miyoshi, H.3
Sugita, T.4
Toriumi, W.5
-
66
-
-
0033638970
-
NEMO/IKKγ-deficient mice model incontinentia pigmenti
-
Schmidt-Supprian M, Bloch W, Courtois G, Addicks K, Israel A, Rajewsky K, Pasparakis M: NEMO/IKKγ-deficient mice model incontinentia pigmenti. Mol Cell 5:981-992, 2000
-
(2000)
Mol Cell
, vol.5
, pp. 981-992
-
-
Schmidt-Supprian, M.1
Bloch, W.2
Courtois, G.3
Addicks, K.4
Israel, A.5
Rajewsky, K.6
Pasparakis, M.7
-
67
-
-
0034740688
-
Requirement of NF-κB/Rel for the development of hair follicles and other epidermal appendices
-
Schmidt-Ullrich R, Aebischer T, Hulsken J, Birchmeier W, Klemm U, Scheidereit C: Requirement of NF-κB/Rel for the development of hair follicles and other epidermal appendices. Development 128:3843-3853, 2001
-
(2001)
Development
, vol.128
, pp. 3843-3853
-
-
Schmidt-Ullrich, R.1
Aebischer, T.2
Hulsken, J.3
Birchmeier, W.4
Klemm, U.5
Scheidereit, C.6
-
68
-
-
0032477945
-
Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB
-
Seitz CS, Lin Q, Deng H, Khavari PA: Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB. Proc Natl Acad Sci USA 95:2307-2312, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2307-2312
-
-
Seitz, C.S.1
Lin, Q.2
Deng, H.3
Khavari, P.A.4
-
69
-
-
0033624673
-
Nuclear factor κB subunits induce epithelial cell growth arrest
-
Seitz CS, Deng H, Hinata K, Lin Q, Khavari PA: Nuclear factor κB subunits induce epithelial cell growth arrest. Cancer Res 60:4085-4092, 2000a
-
(2000)
Cancer Res
, vol.60
, pp. 4085-4092
-
-
Seitz, C.S.1
Deng, H.2
Hinata, K.3
Lin, Q.4
Khavari, P.A.5
-
70
-
-
0033621589
-
NF-κB determines localization and features of cell death in epidermis
-
Seitz CS, Freiberg RA, Hinata K, Khavari PA: NF-κB determines localization and features of cell death in epidermis. J Clin Invest 105:253-260, 2000b
-
(2000)
J Clin Invest
, vol.105
, pp. 253-260
-
-
Seitz, C.S.1
Freiberg, R.A.2
Hinata, K.3
Khavari, P.A.4
-
71
-
-
0029784760
-
The peroxisome proliferator-activated receptor α is a phosphoprotein: Regulation by insulin
-
Shalev A, Siegrist-Kaiser CA, Yen PM, Wahli W, Burger AG, Chin WW, Meier CA: The peroxisome proliferator-activated receptor α is a phosphoprotein: Regulation by insulin. Endocrinol 137:4499-4502, 1996
-
(1996)
Endocrinol
, vol.137
, pp. 4499-4502
-
-
Shalev, A.1
Siegrist-Kaiser, C.A.2
Yen, P.M.3
Wahli, W.4
Burger, A.G.5
Chin, W.W.6
Meier, C.A.7
-
72
-
-
0032565868
-
Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators
-
Staels B, Koenig W, Habib A, et al: Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators. Nature 393:790-793, 1998
-
(1998)
Nature
, vol.393
, pp. 790-793
-
-
Staels, B.1
Koenig, W.2
Habib, A.3
-
73
-
-
0030755596
-
Psoriasis
-
Stern RS: Psoriasis. Lancet 350:349-353, 1997
-
(1997)
Lancet
, vol.350
, pp. 349-353
-
-
Stern, R.S.1
-
74
-
-
0034712933
-
15-Deoxy-δ12,14-prostaglandin J2 inhibits multiple steps in the NF-κB signaling pathway
-
Straus DS, Pascual G, Li M, et al: 15-deoxy-δ12,14-prostaglandin J2 inhibits multiple steps in the NF-κB signaling pathway. Proc Natl Acad Sci USA 97:4844-4849, 2000
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4844-4849
-
-
Straus, D.S.1
Pascual, G.2
Li, M.3
-
75
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response
-
Su CG, Wen X, Bailey ST, et al: A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response. J Clin Invest 104:383-389, 1999
-
(1999)
J Clin Invest
, vol.104
, pp. 383-389
-
-
Su, C.G.1
Wen, X.2
Bailey, S.T.3
-
76
-
-
0033537757
-
Limb and skin abnormalities in mice lacking IKKα
-
Takeda K, Takeuchi O, Tsujimura T, et al: Limb and skin abnormalities in mice lacking IKKα. Science 284:313-316, 1999
-
(1999)
Science
, vol.284
, pp. 313-316
-
-
Takeda, K.1
Takeuchi, O.2
Tsujimura, T.3
-
77
-
-
0035893364
-
Critical roles of PPAR β/δ in keratinocyce response to inflammation
-
Tan NS, Michalik L, Noy N, et al: Critical roles of PPAR β/δ in keratinocyce response to inflammation. Genes Dev 15:3263-3277, 2001
-
(2001)
Genes Dev
, vol.15
, pp. 3263-3277
-
-
Tan, N.S.1
Michalik, L.2
Noy, N.3
-
78
-
-
0033950099
-
Role of neutrophils in induction of acute inflammation in T-cell-mediated immune dermatosis, psoriasis: A neutrophil-associated inflammation-boosting loop
-
Terui T, Ozawa M, Tagami H: Role of neutrophils in induction of acute inflammation in T-cell-mediated immune dermatosis, psoriasis: A neutrophil-associated inflammation-boosting loop. Exp Dermatol 9:1-10, 2000
-
(2000)
Exp Dermatol
, vol.9
, pp. 1-10
-
-
Terui, T.1
Ozawa, M.2
Tagami, H.3
-
79
-
-
0037106540
-
Inhibition of PPAR-mediated keratinocyte differentiation by lipoxygenase inhibitors
-
Thuillier P, Brash AR, Kehrer JP, et al: Inhibition of PPAR-mediated keratinocyte differentiation by lipoxygenase inhibitors. Biochem J 366:901-910, 2002
-
(2002)
Biochem J
, vol.366
, pp. 901-910
-
-
Thuillier, P.1
Brash, A.R.2
Kehrer, J.P.3
-
80
-
-
0027439191
-
The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response
-
Uyemura K, Yamamura M, Fivenson DF, Modlin RL, Nickoloff BJ: The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J Invest Dermatol 101:701-705, 1993
-
(1993)
J Invest Dermatol
, vol.101
, pp. 701-705
-
-
Uyemura, K.1
Yamamura, M.2
Fivenson, D.F.3
Modlin, R.L.4
Nickoloff, B.J.5
-
81
-
-
17744392617
-
Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid
-
Westergaard M, Henningsen J, Svendsen ML, et al: Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. J Invest Dermatol 116:702-712, 2001
-
(2001)
J Invest Dermatol
, vol.116
, pp. 702-712
-
-
Westergaard, M.1
Henningsen, J.2
Svendsen, M.L.3
-
82
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
Willson TM, Brown PJ, Sternbach DD, Henke BR: The PPARs: From orphan receptors to drug discovery. J Med Chem 43:527-550, 2000
-
(2000)
J Med Chem
, vol.43
, pp. 527-550
-
-
Willson, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
83
-
-
0022450566
-
Stereochemical difference between 12-hydroxy-5,8,10,14-eicosatetraenoic acid in platelets and psoriatic lesions
-
Woollard PM: Stereochemical difference between 12-hydroxy-5,8,10,14- eicosatetraenoic acid in platelets and psoriatic lesions. Biochem Biophys Res Commun 136: 169-176, 1986
-
(1986)
Biochem Biophys Res Commun
, vol.136
, pp. 169-176
-
-
Woollard, P.M.1
-
84
-
-
0033119162
-
Coactivator and corepressor complexes in nuclear receptor function
-
Xu L, Glass CK, Rosenfeld MG: Coactivator and corepressor complexes in nuclear receptor function. Curr Opin Genet Dev 9:140-147, 1999
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 140-147
-
-
Xu, L.1
Glass, C.K.2
Rosenfeld, M.G.3
-
85
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
Yu K, Bayona W, Kallen CB, et al: Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J Biol Chem 270:23975-23983, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
|