-
1
-
-
0030612740
-
PPARγ induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A
-
Altiok S, Xu M, Spiegelman BM: PPARγ induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev 11:1987-1998, 1997
-
(1997)
Genes Dev
, vol.11
, pp. 1987-1998
-
-
Altiok, S.1
Xu, M.2
Spiegelman, B.M.3
-
2
-
-
0033213637
-
PPARγ is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES, et al: PPARγ is required for placental, cardiac, and adipose tissue development. Mol Cell 4:585-595, 1999
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
-
3
-
-
0024274394
-
Malignant progression of papilloma-derived keratinocytes: Differential effects of the ras, neu, and p53 oncogenes
-
Dotto GP, O'Connell J, Patskan G, Conti C, Ariza A, Slaga TJ: Malignant progression of papilloma-derived keratinocytes: Differential effects of the ras, neu, and p53 oncogenes. Mol Carcinog 1:171-179, 1988
-
(1988)
Mol Carcinog
, vol.1
, pp. 171-179
-
-
Dotto, G.P.1
O'Connell, J.2
Patskan, G.3
Conti, C.4
Ariza, A.5
Slaga, T.J.6
-
4
-
-
0036714972
-
15-Deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial ceils: Evidence for ERK1/2 signaling pathway blockade
-
Eligini S, Banfi C, Brambilla M, et al: 15-deoxy-delta12,14-Prostaglandin J2 inhibits tissue factor expression in human macrophages and endothelial ceils: Evidence for ERK1/2 signaling pathway blockade. Thromb Haemost 88:524-532, 2002
-
(2002)
Thromb Haemost
, vol.88
, pp. 524-532
-
-
Eligini, S.1
Banfi, C.2
Brambilla, M.3
-
5
-
-
0032555196
-
Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
-
Elstner E, Muller C, Koshizuka K, et al: Ligands for peroxisome proliferator-activated receptor γ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice. Proc Natl Acad Sci USA 95:8806-8811, 1998
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8806-8811
-
-
Elstner, E.1
Muller, C.2
Koshizuka, K.3
-
6
-
-
0034892766
-
Peroxisome proliferator-activated receptor-γ: From adipogenesis to carcinogenesis
-
Fajas L, Debril MB, Auwerx J: Peroxisome proliferator-activated receptor-γ: From adipogenesis to carcinogenesis. J Mol Endocrinol 27:1-9, 2001
-
(2001)
J Mol Endocrinol
, vol.27
, pp. 1-9
-
-
Fajas, L.1
Debril, M.B.2
Auwerx, J.3
-
7
-
-
0037699445
-
PPARγ controls cell proliferation and apoptosis in an RB-dependent manner
-
Fajas L, Egler V, Reiter R, Miard S, Lefebvre AM, Auwerx J: PPARγ controls cell proliferation and apoptosis in an RB-dependent manner. Oncogene 22:4186-4193, 2003
-
(2003)
Oncogene
, vol.22
, pp. 4186-4193
-
-
Fajas, L.1
Egler, V.2
Reiter, R.3
Miard, S.4
Lefebvre, A.M.5
Auwerx, J.6
-
8
-
-
0344443788
-
Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation
-
Gardner OS, Dewar BJ, Earp HS, Samet JM, Graves LM: Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation. J Biol Chem 278:46261-46269, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 46261-46269
-
-
Gardner, O.S.1
Dewar, B.J.2
Earp, H.S.3
Samet, J.M.4
Graves, L.M.5
-
9
-
-
0034007387
-
A dominant-negative peroxisome proliferator-activated receptor γ (PPARγ) mutant is a constitutive repressor and inhibits PPARγ-mediated adipogenesis
-
Gurnell M, Wentworth JM, Agostini M, et al: A dominant-negative peroxisome proliferator-activated receptor γ (PPARγ) mutant is a constitutive repressor and inhibits PPARγ-mediated adipogenesis. J Biol Chem 275:5754-5759, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 5754-5759
-
-
Gurnell, M.1
Wentworth, J.M.2
Agostini, M.3
-
10
-
-
0036314868
-
Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor γ agonists 15-deoxy-delta(12,14)- prostaglandin J(2), ciglitazone, and GW1929
-
Huang WC, Chio CC, Chi KH, Wu HM, Lin WW: Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor γ agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929. Exp Cell Res 277:192-200, 2002
-
(2002)
Exp Cell Res
, vol.277
, pp. 192-200
-
-
Huang, W.C.1
Chio, C.C.2
Chi, K.H.3
Wu, H.M.4
Lin, W.W.5
-
11
-
-
0038776380
-
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
-
Hu E, Kim JB, Sarraf P, Spiegelman BM: Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science 274:2100-2103, 1996
-
(1996)
Science
, vol.274
, pp. 2100-2103
-
-
Hu, E.1
Kim, J.B.2
Sarraf, P.3
Spiegelman, B.M.4
-
12
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann I, Green S: Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347:645-650, 1990
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
13
-
-
0037188311
-
Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells
-
Kim JA, Park KS, Kim HI, Oh SY, Ahn Y, Oh JW, Choi KY: Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells. Cancer Lett 179:185-195, 2002
-
(2002)
Cancer Lett
, vol.179
, pp. 185-195
-
-
Kim, J.A.1
Park, K.S.2
Kim, H.I.3
Oh, S.Y.4
Ahn, Y.5
Oh, J.W.6
Choi, K.Y.7
-
14
-
-
0035035402
-
Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines
-
Koga H, Sakisaka S, Harada M, et al: Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines. Hepatology 33:1087-1097, 2001
-
(2001)
Hepatology
, vol.33
, pp. 1087-1097
-
-
Koga, H.1
Sakisaka, S.2
Harada, M.3
-
15
-
-
0032145363
-
Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo
-
Kubota T, Koshizuka K, Williamson EA, et al: Ligand for peroxisome proliferator-activated receptor γ (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo. Cancer Res 58:3344-3352, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 3344-3352
-
-
Kubota, T.1
Koshizuka, K.2
Williamson, E.A.3
-
16
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA: An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ). J Biol Chem 270:12953-12956, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
17
-
-
0037119433
-
MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta (12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor γ-independent mechanisms involving reactive oxygenated species
-
Lennon AM, Ramauge M, Dessouroux A, Pierre M: MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta (12-14)- prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor γ-independent mechanisms involving reactive oxygenated species. J Biol Chem 277:29681-29685, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 29681-29685
-
-
Lennon, A.M.1
Ramauge, M.2
Dessouroux, A.3
Pierre, M.4
-
18
-
-
0033773041
-
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover
-
Lin S, Wang W, Wilson GM, Yang X, Brewer G, Holbrook NJ, Gorospe M: Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover. Mol Cell Biol 20:7903-7913, 2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7903-7913
-
-
Lin, S.1
Wang, W.2
Wilson, G.M.3
Yang, X.4
Brewer, G.5
Holbrook, N.J.6
Gorospe, M.7
-
19
-
-
0034642509
-
Deregulated expression of cyclin D1 overrides antimitogenic signals
-
Martinez LA, Chen Y, Pavone A, Fischer SM, Conti CJ: Deregulated expression of cyclin D1 overrides antimitogenic signals. Oncogene 19:315-322, 2000
-
(2000)
Oncogene
, vol.19
, pp. 315-322
-
-
Martinez, L.A.1
Chen, Y.2
Pavone, A.3
Fischer, S.M.4
Conti, C.J.5
-
20
-
-
0035921419
-
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)α and PPARβ mutant mice
-
Michalik L, Desvergne B, Tan NS, et al: Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)α and PPARβ mutant mice. J Cell Biol 154:799-814, 2001
-
(2001)
J Cell Biol
, vol.154
, pp. 799-814
-
-
Michalik, L.1
Desvergne, B.2
Tan, N.S.3
-
21
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ
-
Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM: Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93:229-240, 1998
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.3
Chen, H.4
Evans, R.M.5
-
22
-
-
0035881317
-
Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation
-
Palakurthi SS, Aktas H, Grubissich LM, Mortensen RM, Halperin JA: Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation. Cancer Res 61:6213-6218, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 6213-6218
-
-
Palakurthi, S.S.1
Aktas, H.2
Grubissich, L.M.3
Mortensen, R.M.4
Halperin, J.A.5
-
23
-
-
0035873953
-
Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN
-
Patel L, Pass I, Coxon P, Downes CP, Smith SA, Macphee CH: Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN. Curr Biol 11:764-768, 2001
-
(2001)
Curr Biol
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
24
-
-
0035199286
-
The peroxisome proliferator-activated receptor γ is an inhibitor of ErbBs activity in human breast cancer cells
-
Pignatelli M, Cortes-Canteli M, Lai C, Santos A, Perez-Castillo A: The peroxisome proliferator-activated receptor γ is an inhibitor of ErbBs activity in human breast cancer cells. J Cell Sci 114:4117-4126, 2001
-
(2001)
J Cell Sci
, vol.114
, pp. 4117-4126
-
-
Pignatelli, M.1
Cortes-Canteli, M.2
Lai, C.3
Santos, A.4
Perez-Castillo, A.5
-
25
-
-
0037374018
-
Peroxisome proliferator-activated receptor γ agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor α in MCF-7 breast cancer cells
-
Qin C, Burghardt R, Smith R, Wormke M, Stewart J, Safe S: Peroxisome proliferator-activated receptor γ agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor α in MCF-7 breast cancer cells. Cancer Res 63:958-964, 2003
-
(2003)
Cancer Res
, vol.63
, pp. 958-964
-
-
Qin, C.1
Burghardt, R.2
Smith, R.3
Wormke, M.4
Stewart, J.5
Safe, S.6
-
26
-
-
0035851187
-
PPARα: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen ED, Spiegelman BM: PPARα: A nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 276:37731-37734, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
27
-
-
0026346885
-
Alterations of the p53 tumor suppressor gene during mouse skin tumor progression
-
Ruggeri B, Caamano J, Goodrow T, et al: Alterations of the p53 tumor suppressor gene during mouse skin tumor progression. Cancer Res 51:6615-6621, 1991
-
(1991)
Cancer Res
, vol.51
, pp. 6615-6621
-
-
Ruggeri, B.1
Caamano, J.2
Goodrow, T.3
-
28
-
-
0031671246
-
Differentiation and reversal of malignant changes in colon cancer through PPARγ
-
Sarraf P, Mueller E, Jones D, et al: Differentiation and reversal of malignant changes in colon cancer through PPARγ. Nat Med 4:1046-1052, 1998
-
(1998)
Nat Med
, vol.4
, pp. 1046-1052
-
-
Sarraf, P.1
Mueller, E.2
Jones, D.3
-
30
-
-
0033647407
-
Activators of peroxisome proliferator-activated receptor-α partially inhibit mouse skin tumor promotion
-
Thuillier P, Anchiraico GJ, Nickel KP, et al: Activators of peroxisome proliferator-activated receptor-α partially inhibit mouse skin tumor promotion. Mol Carcinog 29:134-142, 2000
-
(2000)
Mol Carcinog
, vol.29
, pp. 134-142
-
-
Thuillier, P.1
Anchiraico, G.J.2
Nickel, K.P.3
-
31
-
-
12644265334
-
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor
-
Tontonoz P, Singer S, Forman BM, et al: Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor. Proc Natl Acad Sci USA 94:237-241, 1997
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 237-241
-
-
Tontonoz, P.1
Singer, S.2
Forman, B.M.3
-
32
-
-
0035052916
-
Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor γ-dependent repression of cyclin D1
-
Wang C, Fu M, D'Amico M, et al: Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor γ-dependent repression of cyclin D1. Mol Cell Biol 21:3057-3070, 2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3057-3070
-
-
Wang, C.1
Fu, M.2
D'Amico, M.3
-
33
-
-
0028243879
-
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
-
Wang TC, Cardiff RD, Zukerberg L, Lees E, Arnold A, Schmidt EV: Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Nature 369:669-671, 1994
-
(1994)
Nature
, vol.369
, pp. 669-671
-
-
Wang, T.C.1
Cardiff, R.D.2
Zukerberg, L.3
Lees, E.4
Arnold, A.5
Schmidt, E.V.6
-
34
-
-
17744392617
-
Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid
-
Westergaard M, Henningsen J, Svendsen ML, et al: Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. J Invest Dermatol 116:702-712, 2001
-
(2001)
J Invest Dermatol
, vol.116
, pp. 702-712
-
-
Westergaard, M.1
Henningsen, J.2
Svendsen, M.L.3
|