Identification of the tryptophan photoproduct 6-formylindolo[3,2-b]carbazole, in cell culture medium, as a factor that controls the background aryl hydrocarbon receptor activity

Toxicological Sciences

Volumn 85, Issue 2, 2005, Pages 935-943

  Öberg, Mattias ^a   Bergander, Linda ^b   Håkansson, Helen ^a   Rannug, Ulf ^b   Rannug, Agneta ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

6 formylindolo 3,2 b carbazole; Aryl hydrocarbon receptor; Light; Tryptophan

Indexed keywords

6 FORMYLINDOLO[3,2 B]CARBAZOLE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; RIBOFLAVIN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOASSAY; CANCER CELL CULTURE; CELL FRACTIONATION; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME SUBSTRATE; FACTORIAL ANALYSIS; HEPATOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LABORATORY; LIGHT EXPOSURE; MASS SPECTROMETRY; NONHUMAN; PHOTOREACTIVITY; RAT; RECEPTOR BINDING; SOLUTION AND SOLUBILITY; ULTRAVIOLET RADIATION;

ANIMALS; CARBAZOLES; CELL LINE, TUMOR; CULTURE MEDIA; CYTOCHROME P-450 CYP1A1; ENZYME INDUCTION; ENZYME INHIBITORS; INDOLES; LIGHT; LIVER NEOPLASMS, EXPERIMENTAL; PHOTOCHEMISTRY; PHOTOSENSITIZING AGENTS; RATS; RECEPTORS, ARYL HYDROCARBON; RIBOFLAVIN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TERATOGENS; TETRACHLORODIBENZODIOXIN; TRYPTOPHAN;

EID: 20544441002     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfi154     Document Type: Article

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