Physicochemical and physiological properties of 5α-cyprinol sulfate, the toxic bile salt of cyprinid fish

Journal of Lipid Research

Volumn 44, Issue 9, 2003, Pages 1643-1651

  Goto, T ^a,c   Holzinger, F ^a   Hagey, L R ^a   Cerre C ^a,d   Ton Nu, H T ^a,e   Schteingart, C D ^a,f   Steinbach, J H ^a   Shneider, B L ^b   Hofmann, A F ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c NUMAZU COLLEGE OF TECHNOLOGY   (Japan)

^d La Jolla Pharmaceutical Company ^*  (Italy)

^e La Jolla Pharmaceutical Company   (United States)

^f Ferring Pharmaceuticals AS   (Denmark)

Author keywords

Bacterial deconjugation; Bile acids; Colestasis; Cyprinus carpio; Fat absorption; Fat digestion; Hepatic transport; Intestinal absorption; Micelles; Solubilization

Indexed keywords

5ALPHA CYPRINOL SULFATE; BILE SALT; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CARP; CELL STRAIN COS7; CHOLESTASIS; CONTROLLED STUDY; DIGESTION; HEMOLYSIS; LIPID ABSORPTION; LIVER METABOLISM; LIVER TOXICITY; MICELLE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SMALL INTESTINE ABSORPTION; SOLUBILIZATION;

ANIMALS; BILE; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; BIOTRANSFORMATION; CARPS; CELL LINE; CHOLESTANOLS; INTESTINES; LIVER; MOLECULAR STRUCTURE; PERFUSION; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SURFACE TENSION;

EID: 0141459452     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1194/jlr.M300155-JLR200     Document Type: Article

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