Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor

Journal of Lipid Research

Volumn 43, Issue 3, 2002, Pages 359-364

  Kliewer, Steven A ^a   Willson, Timothy M ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Cholestasis; Cytochrome P450; Drug drug interaction; Farnesoid X receptor; Lithocholic acid; Nuclear receptor

Indexed keywords

BILE ACID; CELL NUCLEUS RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 3A; FARNESOID X RECEPTOR; FARNESOL; HYPERICUM PERFORATUM EXTRACT; LITHOCHOLIC ACID; PREGNANE X RECEPTOR; RIFAMPICIN; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

BILE ACID METABOLISM; BILIARY CIRRHOSIS; CHOLESTASIS; DETOXIFICATION; DNA BINDING; GENE EXPRESSION REGULATION; LIGAND BINDING; LIVER INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REVIEW; SPECIES DIFFERENCE; XENOBIOTIC METABOLISM;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BILE ACIDS AND SALTS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; HOMEOSTASIS; HUMANS; OXIDOREDUCTASES, N-DEMETHYLATING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; SPECIES SPECIFICITY; XENOBIOTICS;

EID: 0036209248     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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