-
1
-
-
0034127381
-
Carbamazepine-indinavir interaction causes antiretroviral therapy failure
-
Hugen PW, Burger DM, Brinkman K, Ter Hofstede HJ, Schuurman R, Koopmans PP, et al. Carbamazepine-indinavir interaction causes antiretroviral therapy failure. Ann Pharmacother 2000; 34:465-470.
-
(2000)
Ann Pharmacother
, vol.34
, pp. 465-470
-
-
Hugen, P.W.1
Burger, D.M.2
Brinkman, K.3
Ter Hofstede, H.J.4
Schuurman, R.5
Koopmans, P.P.6
-
2
-
-
0034639638
-
Acute heart transplant rejection due to Saint John's wort
-
Ruschitzka F, Meier PJ, Turina M, Luscher TF, Noll G. Acute heart transplant rejection due to Saint John's wort. Lancet 2000; 355:548-549.
-
(2000)
Lancet
, vol.355
, pp. 548-549
-
-
Ruschitzka, F.1
Meier, P.J.2
Turina, M.3
Luscher, T.F.4
Noll, G.5
-
3
-
-
0034095323
-
Pharmacokinetic drug interactions between oral contraceptives and second-generation anticonvulsants
-
Wilbur K, Ensom MH. Pharmacokinetic drug interactions between oral contraceptives and second-generation anticonvulsants. Clin Pharmacokinet 2000; 38:355-365.
-
(2000)
Clin Pharmacokinet
, vol.38
, pp. 355-365
-
-
Wilbur, K.1
Ensom, M.H.2
-
5
-
-
0035038008
-
Phenobarbital response elements of cytochrome P450 genes and nuclear receptors
-
Sueyoshi T, Negishi M. Phenobarbital response elements of cytochrome P450 genes and nuclear receptors. Annu Rev Pharmacol Toxicol 2001; 41:123-143.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 123-143
-
-
Sueyoshi, T.1
Negishi, M.2
-
7
-
-
0344740559
-
Induction of drug metabolism: The role of nuclear receptors
-
Handschin C, Meyer UA. Induction of drug metabolism: the role of nuclear receptors. Pharmacol Rev 2003; 55:649-673.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 649-673
-
-
Handschin, C.1
Meyer, U.A.2
-
8
-
-
0032169485
-
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
-
Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J Clin Invest 1998; 102:1016-1023.
-
(1998)
J Clin Invest
, vol.102
, pp. 1016-1023
-
-
Lehmann, J.M.1
McKee, D.D.2
Watson, M.A.3
Willson, T.M.4
Moore, J.T.5
Kliewer, S.A.6
-
9
-
-
13144260727
-
Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
-
Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-Backman M, et al. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc Natl Acad Sci U S A 1998; 95:12208-12213.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 12208-12213
-
-
Bertilsson, G.1
Heidrich, J.2
Svensson, K.3
Asman, M.4
Jendeberg, L.5
Sydow-Backman, M.6
-
10
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B, Eichelbaum M, Fritz P, Kreichgauer HP, Von Richter O, Zundler J, et al. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest 1999; 104:147-153.
-
(1999)
J Clin Invest
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
Von Richter, O.5
Zundler, J.6
-
11
-
-
0017064628
-
Human colonic adenocarcinoma cells. I. Establishment and description of a new line
-
Tom BH, Rutzky LP, Jakstys MM, Oyasu R, Kaye CI, Kahan BD. Human colonic adenocarcinoma cells. I. Establishment and description of a new line. In Vitro 1976; 12:180-191.
-
(1976)
In Vitro
, vol.12
, pp. 180-191
-
-
Tom, B.H.1
Rutzky, L.P.2
Jakstys, M.M.3
Oyasu, R.4
Kaye, C.I.5
Kahan, B.D.6
-
12
-
-
0035805536
-
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
-
Geick A, Eichelbaum M, Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J Biol Chem 2001; 276:14581-14587.
-
(2001)
J Biol Chem
, vol.276
, pp. 14581-14587
-
-
Geick, A.1
Eichelbaum, M.2
Burk, O.3
-
14
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004; 5:R80.
-
(2004)
Genome Biol
, vol.5
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
-
15
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4:249-264.
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
Hobbs, B.2
Collin, F.3
Beazer-Barclay, Y.D.4
Antonellis, K.J.5
Scherf, U.6
-
16
-
-
11244346557
-
Variance stabilization applied to microarray data calibration and to the quantification of differential expression
-
Huber W, Von Heydebreck A, Sultmann H, Poustka A, Vingron M. Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 2002; 18 (Suppl 1):S96-S104.
-
(2002)
Bioinformatics
, vol.18
, Issue.SUPPL. 1
-
-
Huber, W.1
Von Heydebreck, A.2
Sultmann, H.3
Poustka, A.4
Vingron, M.5
-
17
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Article3
-
Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004; 3:Article3.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
-
-
Smyth, G.K.1
-
18
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 1995; 57:289-300.
-
(1995)
J R Stat Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
19
-
-
0034777488
-
Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4
-
Hustert E, Zibat A, Presecan-Siedel E, Eiselt R, Mueller R, Fuss C, et al. Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4. Drug Metab Dispos 2001; 29:1454-1459.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1454-1459
-
-
Hustert, E.1
Zibat, A.2
Presecan-Siedel, E.3
Eiselt, R.4
Mueller, R.5
Fuss, C.6
-
20
-
-
0024427759
-
The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction
-
Ged C, Rouillon JM, Pichard L, Combalbert J, Bressot N, Bories P, et al. The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction. Br J Clin Pharmacol 1989; 28:373-387.
-
(1989)
Br J Clin Pharmacol
, vol.28
, pp. 373-387
-
-
Ged, C.1
Rouillon, J.M.2
Pichard, L.3
Combalbert, J.4
Bressot, N.5
Bories, P.6
-
21
-
-
0026464616
-
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
-
Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 1992; 90:1871-1878.
-
(1992)
J Clin Invest
, vol.90
, pp. 1871-1878
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Schuetz, J.D.3
Fang, C.4
Watkins, P.B.5
-
22
-
-
0035032568
-
Interindividual variability in inhibition and induction of cytochrome P450 enzymes
-
Lin JH, Lu AY. Interindividual variability in inhibition and induction of cytochrome P450 enzymes. Annu Rev Pharmacol Toxicol 2001; 41:535-567.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 535-567
-
-
Lin, J.H.1
Lu, A.Y.2
-
23
-
-
0032702726
-
The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module
-
Goodwin B, Hodgson E, Liddle C. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol Pharmacol 1999; 56:1329-1339.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 1329-1339
-
-
Goodwin, B.1
Hodgson, E.2
Liddle, C.3
-
24
-
-
0042844649
-
Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter
-
Chen Y, Ferguson SS, Negishi M, Goldstein JA. Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter. Mol Pharmacol 2003; 64:316-324.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 316-324
-
-
Chen, Y.1
Ferguson, S.S.2
Negishi, M.3
Goldstein, J.A.4
-
25
-
-
0034811083
-
Functionally conserved xenobiotic responsive enhancer in cytochrome P450 3A7
-
Bertilsson G, Berkenstam A, Blomquist P. Functionally conserved xenobiotic responsive enhancer in cytochrome P450 3A7. Biochem Biophys Res Commun 2001; 280:139-144.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 139-144
-
-
Bertilsson, G.1
Berkenstam, A.2
Blomquist, P.3
-
26
-
-
0036765751
-
Regulation of human CYP2C9 by the constitutive androstane receptor: Discovery of a new distal binding site
-
Ferguson SS, LeCluyse EL, Negishi M, Goldstein JA. Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site. Mol Pharmacol 2002; 62:737-746.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 737-746
-
-
Ferguson, S.S.1
LeCluyse, E.L.2
Negishi, M.3
Goldstein, J.A.4
-
27
-
-
0033526864
-
Evidence for the presence of a functional pregnane X receptor response element in the CYP3A7 promoter gene
-
Pascussi JM, Jounaidi Y, Drocourt L, Domergue J, Balabaud C, Maurel P, et al. Evidence for the presence of a functional pregnane X receptor response element in the CYP3A7 promoter gene. Biochem Biophys Res Commun 1999; 260:377-381.
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 377-381
-
-
Pascussi, J.M.1
Jounaidi, Y.2
Drocourt, L.3
Domergue, J.4
Balabaud, C.5
Maurel, P.6
-
28
-
-
0037016761
-
Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor
-
Gerbal-Chaloin S, Daujat M, Pascussi JM, Pichard-Garcia L, Vilarem MJ, Maurel P. Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor. J Biol Chem 2002; 277:209-217.
-
(2002)
J Biol Chem
, vol.277
, pp. 209-217
-
-
Gerbal-Chaloin, S.1
Daujat, M.2
Pascussi, J.M.3
Pichard-Garcia, L.4
Vilarem, M.J.5
Maurel, P.6
-
29
-
-
13444249728
-
Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes
-
Glaeser H, Drescher S, Eichelbaum M, Fromm MF. Influence of rifampicin on the expression and function of human intestinal cytochrome P450 enzymes. Br J Clin Pharmacol 2005; 59:199-206.
-
(2005)
Br J Clin Pharmacol
, vol.59
, pp. 199-206
-
-
Glaeser, H.1
Drescher, S.2
Eichelbaum, M.3
Fromm, M.F.4
-
30
-
-
17744397194
-
Genomic organization of the human CYP3A locus: Identification of a new, inducible CYP3A gene
-
Gellner K, Eiselt R, Hustert E, Arnold H, Koch I, Haberl M, et al. Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene. Pharmacogenetics 2001; 11:111-121.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 111-121
-
-
Gellner, K.1
Eiselt, R.2
Hustert, E.3
Arnold, H.4
Koch, I.5
Haberl, M.6
-
31
-
-
0036142429
-
Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital
-
Ueda A, Hamadeh HK, Webb HK, Yamamoto Y, Sueyoshi T, Afshari CA, et al. Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital. Mol Pharmacol 2002; 61:1-6.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 1-6
-
-
Ueda, A.1
Hamadeh, H.K.2
Webb, H.K.3
Yamamoto, Y.4
Sueyoshi, T.5
Afshari, C.A.6
-
32
-
-
0037972688
-
Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor
-
Rosenfeld JM, Vargas R Jr, Xie W, Evans RM. Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Mol Endocrinol 2003; 17:1268-1282.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1268-1282
-
-
Rosenfeld, J.M.1
Vargas Jr, R.2
Xie, W.3
Evans, R.M.4
-
33
-
-
0036765785
-
Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
-
Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol Pharmacol 2002; 62:638-646.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
34
-
-
37349078794
-
Nuclear receptors CAR and PXR activate a drug responsive enhancer of the murine 5-aminolevulinic acid synthase gene
-
Fraser DJ, Zumsteg A, Meyer UA. Nuclear receptors CAR and PXR activate a drug responsive enhancer of the murine 5-aminolevulinic acid synthase gene. J Biol Chem 2003.
-
(2003)
J Biol Chem
-
-
Fraser, D.J.1
Zumsteg, A.2
Meyer, U.A.3
-
35
-
-
0036561247
-
Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR
-
Nishimura M, Yoshitsugu H, Naito S, Hiraoka I. Evaluation of gene induction of drug-metabolizing enzymes and transporters in primary culture of human hepatocytes using high-sensitivity real-time reverse transcription PCR. Yakugaku Zasshi 2002; 122:339-361.
-
(2002)
Yakugaku Zasshi
, vol.122
, pp. 339-361
-
-
Nishimura, M.1
Yoshitsugu, H.2
Naito, S.3
Hiraoka, I.4
-
36
-
-
0032055241
-
Effects of chemical inducers on human microsomal epoxide hydrolase in primary hepatocyte cultures
-
Hassett C, Laurenzana EM, Sidhu JS, Omiecinski CJ. Effects of chemical inducers on human microsomal epoxide hydrolase in primary hepatocyte cultures. Biochem Pharmacol 1998; 55:1059-1069.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1059-1069
-
-
Hassett, C.1
Laurenzana, E.M.2
Sidhu, J.S.3
Omiecinski, C.J.4
-
37
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
-
Tukey RH, Strassburg CP. Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annu Rev Pharmacol Toxicol 2000; 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
38
-
-
0037108916
-
Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR)
-
Sonoda J, Xie W, Rosenfeld JM, Barwick JL, Guzelian PS, Evans RM. Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). Proc Natl Acad Sci U S A 2002; 99:13801-13806.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 13801-13806
-
-
Sonoda, J.1
Xie, W.2
Rosenfeld, J.M.3
Barwick, J.L.4
Guzelian, P.S.5
Evans, R.M.6
-
39
-
-
0030923439
-
Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities
-
Jakobsson PJ, Mancini JA, Riendeau D, Ford-Hutchinson AW. Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities. J Biol Chem 1997; 272:22934-22939.
-
(1997)
J Biol Chem
, vol.272
, pp. 22934-22939
-
-
Jakobsson, P.J.1
Mancini, J.A.2
Riendeau, D.3
Ford-Hutchinson, A.W.4
-
40
-
-
0032781499
-
Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)
-
Kawabe T, Chen ZS, Wada M, Uchiumi T, Ono M, Akiyama S, et al. Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2). FEBS Lett 1999; 456:327-331.
-
(1999)
FEBS Lett
, vol.456
, pp. 327-331
-
-
Kawabe, T.1
Chen, Z.S.2
Wada, M.3
Uchiumi, T.4
Ono, M.5
Akiyama, S.6
-
41
-
-
0033724658
-
The effect of rifampin treatment on intestinal expression of human MRP transporters
-
Fromm MF, Kauffmann HM, Fritz P, Burk O, Kroemer HK, Warzok RW, et al. The effect of rifampin treatment on intestinal expression of human MRP transporters. Am J Pathol 2000; 157:1575-1580.
-
(2000)
Am J Pathol
, vol.157
, pp. 1575-1580
-
-
Fromm, M.F.1
Kauffmann, H.M.2
Fritz, P.3
Burk, O.4
Kroemer, H.K.5
Warzok, R.W.6
-
42
-
-
0034753508
-
Role of ABCG1 and other ABCG family members in lipid metabolism
-
Schmitz G, Langmann T, Heimerl S. Role of ABCG1 and other ABCG family members in lipid metabolism. J Lipid Res 2001; 42: 1513-1520.
-
(2001)
J Lipid Res
, vol.42
, pp. 1513-1520
-
-
Schmitz, G.1
Langmann, T.2
Heimerl, S.3
-
43
-
-
25444529284
-
The human ABCG1 gene: Identification of LXR response elements that modulate expression in macrophages and liver
-
Sabol SL, Brewer HB Jr, Santamarina-Fojo S. The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver. J Lipid Res 2005; 46:2151-2167.
-
(2005)
J Lipid Res
, vol.46
, pp. 2151-2167
-
-
Sabol, S.L.1
Brewer Jr, H.B.2
Santamarina-Fojo, S.3
-
44
-
-
1642457373
-
CYP3A induction by liverXreceptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor
-
Shenoy SD, Spencer TA, Mercer-Haines NA, Alipour M, Gargano MD, Runge-Morris M, et al. CYP3A induction by liverXreceptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor. Drug Metab Dispos 2004; 32:66-71.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 66-71
-
-
Shenoy, S.D.1
Spencer, T.A.2
Mercer-Haines, N.A.3
Alipour, M.4
Gargano, M.D.5
Runge-Morris, M.6
-
45
-
-
0031663606
-
Regulation of rat hepatic cytochrome P450 expression by sterol biosynthesis inhibition: Inhibitors of squalene synthase are potent inducers of CYP2B expression in primary cultured rat hepatocytes and rat liver
-
Kocarek TA, Kraniak JM, Reddy AB. Regulation of rat hepatic cytochrome P450 expression by sterol biosynthesis inhibition: inhibitors of squalene synthase are potent inducers of CYP2B expression in primary cultured rat hepatocytes and rat liver. Mol Pharmacol 1998; 54:474-484.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 474-484
-
-
Kocarek, T.A.1
Kraniak, J.M.2
Reddy, A.B.3
-
46
-
-
0036289448
-
-
Ourlin JC, Handschin C, Kaufmann M, Meyer UA. A Link between cholesterol levels and phenobarbital induction of cytochromes P450. Biochem Biophys Res Commun 2002; 291:378-384.
-
Ourlin JC, Handschin C, Kaufmann M, Meyer UA. A Link between cholesterol levels and phenobarbital induction of cytochromes P450. Biochem Biophys Res Commun 2002; 291:378-384.
-
-
-
-
47
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002; 109:1125-1131.
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
48
-
-
0019481094
-
Rates of sterol synthesis and uptake in the major organs of the rat in vivo
-
Turley SD, Andersen JM, Dietschy JM. Rates of sterol synthesis and uptake in the major organs of the rat in vivo. J Lipid Res 1981; 22:551-569.
-
(1981)
J Lipid Res
, vol.22
, pp. 551-569
-
-
Turley, S.D.1
Andersen, J.M.2
Dietschy, J.M.3
-
49
-
-
0031778894
-
The lipolysis stimulated receptor: A gene at last
-
Bihain BE, Yen FT. The lipolysis stimulated receptor: a gene at last. Curr Opin Lipidol 1998; 9:221-224.
-
(1998)
Curr Opin Lipidol
, vol.9
, pp. 221-224
-
-
Bihain, B.E.1
Yen, F.T.2
-
50
-
-
0033532198
-
Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver
-
Yen FT, Masson M, Clossais-Besnard N, Andre P, Grosset JM, Bougueleret L, et al. Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver. J Biol Chem 1999; 274:13390-13398.
-
(1999)
J Biol Chem
, vol.274
, pp. 13390-13398
-
-
Yen, F.T.1
Masson, M.2
Clossais-Besnard, N.3
Andre, P.4
Grosset, J.M.5
Bougueleret, L.6
-
51
-
-
4344562884
-
Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
-
Arnold KA, Eichelbaum M, Burk O. Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor. Nuclear Recept 2004; 2:1.
-
(2004)
Nuclear Recept
, vol.2
, pp. 1
-
-
Arnold, K.A.1
Eichelbaum, M.2
Burk, O.3
-
52
-
-
0034326252
-
Effects of estrogen on global gene expression: Identification of novel targets of estrogen action
-
Charpentier AH, Bednarek AK, Daniel RL, Hawkins KA, Laflin KJ, Gaddis S, et al. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res 2000; 60:5977-5983.
-
(2000)
Cancer Res
, vol.60
, pp. 5977-5983
-
-
Charpentier, A.H.1
Bednarek, A.K.2
Daniel, R.L.3
Hawkins, K.A.4
Laflin, K.J.5
Gaddis, S.6
-
53
-
-
4544310903
-
Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin
-
Ohta K, Lupo G, Kuriyama S, Keynes R, Holt CE, Harris WA, et al. Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin. Dev Cell 2004; 7:347-358.
-
(2004)
Dev Cell
, vol.7
, pp. 347-358
-
-
Ohta, K.1
Lupo, G.2
Kuriyama, S.3
Keynes, R.4
Holt, C.E.5
Harris, W.A.6
-
54
-
-
33745210139
-
Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells
-
Ichikawa T, Horie-Inoue K, Ikeda K, Blumberg B, Inoue S. Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem 2006; 281:16927-16934.
-
(2006)
J Biol Chem
, vol.281
, pp. 16927-16934
-
-
Ichikawa, T.1
Horie-Inoue, K.2
Ikeda, K.3
Blumberg, B.4
Inoue, S.5
-
55
-
-
33748916602
-
Induction of rat UDP-glucuronosyltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways
-
Shelby MK, Klaassen CD. Induction of rat UDP-glucuronosyltransferases in liver and duodenum by microsomal enzyme inducers that activate various transcriptional pathways. Drug Metab Dispos 2006; 34:1772-1778.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1772-1778
-
-
Shelby, M.K.1
Klaassen, C.D.2
-
56
-
-
33748894676
-
Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes
-
Jigorel E, Le Vee M, Boursier-Neyret C, Parmentier Y, Fardel O. Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes. Drug Metab Dispos 2006; 34:1756-1763.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1756-1763
-
-
Jigorel, E.1
Le Vee, M.2
Boursier-Neyret, C.3
Parmentier, Y.4
Fardel, O.5
-
57
-
-
3042752557
-
Nrf2-dependent gene expressions: A molecular toxicological aspect
-
Numazawa S, Yoshida T. Nrf2-dependent gene expressions: a molecular toxicological aspect. J Toxicol Sci 2004; 29:81-89.
-
(2004)
J Toxicol Sci
, vol.29
, pp. 81-89
-
-
Numazawa, S.1
Yoshida, T.2
-
58
-
-
0035201366
-
Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: Studies with cDNA and oligonucleotide expression arrays
-
Rae JM, Johnson MD, Lippman ME, Flockhart DA. Rifampin is a selective, pleiotropic inducer of drug metabolism genes in human hepatocytes: studies with cDNA and oligonucleotide expression arrays. J Pharmacol Exp Ther 2001; 299:849-857.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 849-857
-
-
Rae, J.M.1
Johnson, M.D.2
Lippman, M.E.3
Flockhart, D.A.4
-
59
-
-
0034964158
-
Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation
-
LeCluyse EL. Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation. Eur J Pharm Sci 2001; 13:343-368.
-
(2001)
Eur J Pharm Sci
, vol.13
, pp. 343-368
-
-
LeCluyse, E.L.1
-
60
-
-
0037192501
-
Molecular determinants for the tissue specificity of SERMs
-
Shang Y, Brown M. Molecular determinants for the tissue specificity of SERMs. Science 2002; 295:2465-2468.
-
(2002)
Science
, vol.295
, pp. 2465-2468
-
-
Shang, Y.1
Brown, M.2
-
61
-
-
0036009146
-
Regulation of cholesterol-7alpha- hydroxylase: BAREly missing a SHP
-
Davis RA, Miyake JH, Hui TY, Spann NJ. Regulation of cholesterol-7alpha- hydroxylase: BAREly missing a SHP. J Lipid Res 2002; 43:533-543.
-
(2002)
J Lipid Res
, vol.43
, pp. 533-543
-
-
Davis, R.A.1
Miyake, J.H.2
Hui, T.Y.3
Spann, N.J.4
-
62
-
-
0042787016
-
The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity
-
Ourlin JC, Lasserre F, Pineau T, Fabre JM, Sa-Cunha A, Maurel P, et al. The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity. Mol Endocrinol 2003; 17:1693-1703.
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1693-1703
-
-
Ourlin, J.C.1
Lasserre, F.2
Pineau, T.3
Fabre, J.M.4
Sa-Cunha, A.5
Maurel, P.6
-
63
-
-
0037422578
-
Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor
-
Goodwin B, Gauthier KC, Umetani M,Watson MA, Lochansky MI, Collins JL, et al. Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor. Proc Natl Acad Sci U S A 2003; 100:223-228.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 223-228
-
-
Goodwin, B.1
Gauthier, K.C.2
Umetani, M.3
Watson, M.A.4
Lochansky, M.I.5
Collins, J.L.6
-
64
-
-
0037417994
-
Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance
-
Dussault I, Yoo HD, Lin M, Wang E, Fan M, Batta AK, et al. Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance. Proc Natl Acad Sci U S A 2003; 100:833-838.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 833-838
-
-
Dussault, I.1
Yoo, H.D.2
Lin, M.3
Wang, E.4
Fan, M.5
Batta, A.K.6
-
65
-
-
0033583336
-
6Alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes
-
Araya Z,Wikvall K. 6Alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. Biochim Biophys Acta 1999; 1438:47-54.
-
(1999)
Biochim Biophys Acta
, vol.1438
, pp. 47-54
-
-
Araya, Z.1
Wikvall, K.2
-
66
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, et al. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci U S A 2001; 98:3375-3380.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 3375-3380
-
-
Xie, W.1
Radominska-Pandya, A.2
Shi, Y.3
Simon, C.M.4
Nelson, M.C.5
Ong, E.S.6
-
67
-
-
0033745088
-
Hepatic secretion of conjugated drugs and endogenous substances
-
Keppler D, Konig J. Hepatic secretion of conjugated drugs and endogenous substances. Semin Liver Dis 2000; 20:265-272.
-
(2000)
Semin Liver Dis
, vol.20
, pp. 265-272
-
-
Keppler, D.1
Konig, J.2
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