메뉴 건너뛰기




Volumn 291, Issue 2, 2002, Pages 378-384

A link between cholesterol levels and phenobarbital induction of cytochromes P450

Author keywords

Bile acids; Cholesterol homeostasis; CYP2H1; CYP3A37; Cytochrome P450; Drug induction; Phenobarbital; Squalestatin; Sterols

Indexed keywords

25 HYDROXYCHOLESTEROL; BILE ACID; CYTOCHROME P450 2H1; CYTOCHROME P450 3A37; CYTOCHROME P450 ISOENZYME; MESSENGER RNA; PHENOBARBITAL; SQUALENE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; ZARAGOZIC ACID A;

EID: 0036289448     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6464     Document Type: Article
Times cited : (27)

References (30)
  • 9
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 10
    • 0033612369 scopus 로고    scopus 로고
    • Nuclear orphan receptors control cholesterol catabolism
    • (1999) Cell , vol.97 , pp. 539-542
    • Russell, D.W.1
  • 16
    • 0031663606 scopus 로고    scopus 로고
    • Regulation of rat hepatic cytochrome P450 expression by sterol biosynthesis inhibition: Inhibitors of squalene synthase are potent inducers of CYP2B expression in primary cultured rat hepatocytes and rat liver
    • (1998) Mol. Pharmacol. , vol.54 , pp. 474-484
    • Kocarek, T.A.1    Kraniak, J.M.2    Reddy, A.B.3
  • 19
    • 0034607818 scopus 로고    scopus 로고
    • A conserved nuclear receptor consensus sequence (DR-4) mediates transcriptional activation of the chicken CYP2H1 gene by phenobarbital in a hepatoma cell line
    • (2000) J. Biol. Chem. , vol.275 , pp. 13362-13369
    • Handschin, C.1    Meyer, U.A.2
  • 29
    • 0023221084 scopus 로고
    • Therapeutic use of phenobarbital in intrahepatic cholestasis. Inductions in bile acid metabolism
    • (1987) Pharmacol. Ther. , vol.33 , pp. 153-155
    • Back, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.