Minireview: Nuclear receptor coactivators - An update

Endocrinology

Volumn 143, Issue 7, 2002, Pages 2461-2465

  McKenna, Neil J ^a   O'Malley, Bert W ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ADENOSINE TRIPHOSPHATASE; CELL NUCLEUS RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLUCOCORTICOID RECEPTOR; LIGAND; SOMATOMEDIN C; STEROID HORMONE; STEROID RECEPTOR COACTIVATOR 1; TRANSCRIPTION FACTOR;

COMPLEX FORMATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONE ACTION; HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 0036284103     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.143.7.8892     Document Type: Short Survey

References (45)

1. The steroid and thyroid hormone receptor superfamily
2. The RXR heterodimers and orphan receptors
3. Molecular mechanisms of action of steroid/thyroid receptor superfamily members
4. Coregulator codes of transcriptional regulation by nuclear receptors
5. Combinatorial control of gene expression by nuclear receptors and coregulators
6. A signature motif in transcriptional co-activators mediates binding to nuclear receptors
7. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
8. Peptide antagonists of the human estrogen receptor
9. Transcriptional regulation: SWitching circuitry
10. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily
11. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
12. GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors
13. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
14. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
15. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
16. RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2
17. A transcriptional coactivator, steroid receptor coactivator-3, selectively augments steroid receptor transcriptional activity
18. TRAM-1, a novel 160-kDa thyroid hormone receptor activator molecule exhibits distinct properties from steroid receptor coactivator-1
19. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer
20. Steroid receptor coactivator-1 is a histone acetyltransferase
21. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene
22. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development
23. Regulation of somatic growth by the p160 coactivator p/CIP
24. Role of CBP/p300 in nuclear receptor signalling
25. Binding and modulation of p53 by p300/CBP coactivators
26. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
27. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
28. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
29. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
30. Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action
31. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase
32. Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases
33. Steroid hormone receptors and their regulation by phosphorylation
34. Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor
35. AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor
36. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
37. Regulation of alternative splicing by the ATp-dependent DEAD box RNA helicase p72
38. Differential recruitment of the mammalian mediator subunit TRAP220 by estrogen receptors ERα and ERβ
39. Structure-function evaluation of ER α and β interplay with SRC family coactivators. ER selective ligands
40. Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog
41. Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes
42. Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-α and estrogen receptor-β: Correlations with biological character and distinct differences among SRC coactivator family members
43. A unique PPARγ ligand with potent insulin-sensitizing yet weak adipogenic activity
44. Ser-884 adjacent to the LXXLL motif of coactivator TRBP defines selectivity for ERs and TRs
45. Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction