Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 7, 2004, Pages 1721-1727

  Elmore, Steven W ^a   Pratt, John K ^a   Coghlan, Michael J ^a,c   Mao, Yue ^a   Green, Brian E ^a   Anderson, David D ^a   Stashko, Michael A ^a   Lin, Chun W ^a   Falls, Douglas ^a   Nakane, Masaki ^a   Miller, Loan ^a   Tyree, Curtis M ^b   Miner, Jeffrey N ^b   Lane, Ben ^a  

^a ABBOTT LABORATORIES   (United States)

^b LIGAND PHARMACEUTICALS INC   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

10 METHOXY 2,2,4 TRIMETHYLBENZOPYRANO[3,4 F]QUINOLINE; GLUCOCORTICOID; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; DRUG STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

BINDING, COMPETITIVE; GLUCOCORTICOIDS; HUMANS; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; SUPPRESSION, GENETIC; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC;

EID: 12144286283     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.044     Document Type: Article

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