Dissociated glucocorticoids equipotently inhibit cytokine- and cAMP-induced matrix degrading proteases in rat mesangial cells

Biochemical Pharmacology

Volumn 70, Issue 3, 2005, Pages 433-445

  Eberhardt, Wolfgang ^a   Kilz, Tobias ^a   Akool, El Sayed ^a   Müller, Roswitha ^a   Pfeilschifter, Josef ^a,b  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b Al Azhar University   (Egypt)

Author keywords

Dissociated glucocorticoids; Extracellular matrix; Matrix metalloproteinase 9; Proteases; Tissue plasminogen activator

Indexed keywords

CYCLIC AMP; CYTOKINE; DEXAMETHASONE; ENZYME INHIBITOR; GELATINASE B; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR AGONIST; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE; RU 24782; RU 24858; RU 40066; SYNAPTOTAGMIN; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DNA BINDING; DRUG POTENCY; EXTRACELLULAR MATRIX; MESANGIUM CELL; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REPORTER GENE;

ANIMALS; CELLS, CULTURED; CYCLIC AMP; CYTOKINES; EXTRACELLULAR MATRIX; GLOMERULAR MESANGIUM; GLUCOCORTICOIDS; HUMANS; MATRIX METALLOPROTEINASES; PROTEASE INHIBITORS; RATS;

EID: 21344450122     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.05.007     Document Type: Article

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