Dexamethasone inhibits inducible nitric-oxide synthase expression and nitric oxide production by destabilizing mRNA in lipopolysaccharide-treated macrophages

Molecular Pharmacology

Volumn 62, Issue 3, 2002, Pages 698-704

  Korhonen, Riku ^b   Lahti, Aleksi ^b   Hämäläinen, Mari ^b   Kankaanranta, Hannu ^b   Moilanen, Eeva ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYCLOHEXIMIDE; DACTINOMYCIN; DEXAMETHASONE; GAMMA INTERFERON; GLUCOCORTICOID; LIPOPOLYSACCHARIDE; MESSENGER RNA; MIFEPRISTONE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN SYNTHESIS INHIBITOR; RU 24858; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HALF LIFE TIME; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; REGULATORY MECHANISM;

ANIMALS; CELLS, CULTURED; DEXAMETHASONE; GENE EXPRESSION; GLUCOCORTICOIDS; HYDROXYCORTICOSTEROIDS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RNA STABILITY; RNA, MESSENGER;

EID: 0036765329     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.3.698     Document Type: Article

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