Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 8, 2000, Pages 3919-3924

  De Bosscher, Karolien ^a   Berghe, Wim Vanden ^a   Vermeulen, Linda ^a   Plaisance, Stéphane ^a,b   Boone, Elke ^a   Haegeman, Guy ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b Cardiac Unit   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; NUCLEAR FACTOR; PROTEIN P300; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR;

ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG MECHANISM; EMBRYO; GENE CONSTRUCT; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFLAMMATION; POINT MUTATION; PRIORITY JOURNAL; REPORTER GENE; TATA BOX; TRANSACTIVATION;

BASE SEQUENCE; DNA PRIMERS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; MUTAGENESIS, SITE-DIRECTED; NF-KAPPA B; PROMOTER REGIONS (GENETICS); SACCHAROMYCES CEREVISIAE PROTEINS; TATA BOX; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034636021     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.8.3919     Document Type: Article

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