p65-activated histone acetyltransferase activity is repressed by glucocorticoids. Mifepristone fails to recruit HDAC2 to the p65-HAT complex

Journal of Biological Chemistry

Volumn 276, Issue 32, 2001, Pages 30208-30215

  Ito, Kazuhiro ^b   Jazrawi, Elen ^b   Cosio, Borja ^b   Barnes, Peter J ^b   Adcock, Ian M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; GENETIC ENGINEERING; PATIENT TREATMENT; PHARMACODYNAMICS;

GENE TRANSCRIPTION;

BIOCHEMISTRY;

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HISTONE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 2; INTERLEUKIN 1BETA; MIFEPRISTONE; PROTEIN P65 HISTONE ACETYLTRANSFERASE COMPLEX; RECOMBINANT PROTEIN; SYNAPTOTAGMIN; UNCLASSIFIED DRUG; ACYLTRANSFERASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HISTONE DEACETYLASE-2; HORMONE ANTAGONIST; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; LYSINE; NONSTEROID ANTIINFLAMMATORY AGENT; REPRESSOR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR RELA;

ACETYLATION; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFLAMMATORY DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; CELL CULTURE; CELL NUCLEUS; CHROMATIN; DOSE RESPONSE; DRUG POTENTIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METABOLISM; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERODIAGNOSIS; WESTERN BLOTTING;

ACETYLATION; ACETYLTRANSFERASES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; CELL NUCLEUS; CHROMATIN; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUCOCORTICOIDS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASES; HISTONES; HORMONE ANTAGONISTS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-1; LYSINE; MIFEPRISTONE; NF-KAPPA B; PRECIPITIN TESTS; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0035839497     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103604200     Document Type: Article

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