Human cytochrome P450 family 4 enzymes: Function, genetic variation and regulation

Drug Metabolism Reviews

Volumn 39, Issue 2-3, 2007, Pages 515-538

  Hsu, Mei Hui ^a   Savas, Üzen ^a   Griffin, Keith J ^a   Johnson, Eric F ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Cytochrome P450 4; Fatty acid hydroxylation; Gene regulation; P450 4A11; P450 4A22; P450 4F2; P450 4F3B; Species differences

Indexed keywords

2,5 BIS(4 AMIDINOPHENYL)FURAN; ARACHIDONIC ACID; CLOFIBRATE; CYTOCHROME P450; CYTOCHROME P450 4; CYTOCHROME P450 4A; CYTOCHROME P450 4A11; CYTOCHROME P450 4A22; CYTOCHROME P450 4F2; CYTOCHROME P450 4F3B; DIAMINE; DIOXIN; EBASTINE; ENZYME INHIBITOR; ERYTHROMYCIN; GAMMA TOCOPHEROL; HYDROXYICOSATETRAENOIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LAURIC ACID; LEUKOTRIENE; LEUKOTRIENE B4; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PHENOBARBITAL; PROSTANOID; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TS 011; UNCLASSIFIED DRUG; UNINDEXED DRUG; UNSPECIFIC MONOOXYGENASE; XENOBIOTIC AGENT;

AFRICAN TRYPANOSOMIASIS; AMINO ACID SEQUENCE; DRUG BIOAVAILABILITY; ENZYME ACTIVITY; GENE FREQUENCY; GENETIC REGULATION; GENETIC VARIABILITY; HUMAN; HYDROXYLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STROKE;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; RODENTIA; VARIATION (GENETICS);

EID: 34548390084     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.1080/03602530701468573     Document Type: Review

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