The Drosophila sanpodo gene controls sibling cell fate and encodes a tropomodulin homolog, an actin/tropomyosin-associated protein

Development

Volumn 125, Issue 10, 1998, Pages 1845-1856

  Dye, Catherine A ^a   Lee, Ja Kyeong ^a,c   Atkinson, Richard C ^a   Brewster, Rachel ^b   Han, Pyung Lim ^a,d   Bellen, Hugo J ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Ajou University   (South Korea)

^d Hanhyo Institute of Technology   (South Korea)

Author keywords

Actin; Drosophila; Glia; Neurogenesis; Notch; numb; sanpodo; Tropomodulin

Indexed keywords

F ACTIN; TROPOMODULIN; TROPOMYOSIN;

ANIMAL TISSUE; ARTICLE; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; GENETIC EPISTASIS; MUTATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PERIPHERAL NERVOUS SYSTEM; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; CLONING, MOLECULAR; DROSOPHILA; DROSOPHILA PROTEINS; EPISTASIS, GENETIC; GENES, INSECT; JUVENILE HORMONES; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; NEUROGLIA; NEURONS; PERIPHERAL NERVOUS SYSTEM; RECEPTORS, NOTCH; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TROPOMODULIN;

ANIMALIA; ARACHNIDA; HEXAPODA; INVERTEBRATA; VERTEBRATA;

EID: 0031745685     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (72)

1. Akiyama, Y., Hosoya, T., Poole, A. M. and Hotta, Y. (1996). The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals. Proc. Natl. Acad. Sci. USA 93, 14912-14916.
2. Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E. (1995). Notch signaling. Science 268, 225-232.
3. Babcock, G. G. and Fowler, V. M. (1994). Isoform-specifk interaction of tropomodulin with skeletal muscle and erythrocyte tropomyosins. J. Biol. Chem. 269, 27510-27518.
4. Bellen, H. J., Kooyer, S., D'Evelyn, D. and Pearlman, J. (1992). The Drosophila Couch potato protein is expressed in nuclei of peripheral neuronal precursors and shows homology to RNA-binding proteins. Genes Dev. 6, 2125-2136.
5. Bier, E. et al. (1989). Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. Genes Dev. 3, 1273-1287.
6. Blaumueller, C., Huilin, Q., Zagouras, P. and Artavanis-Tsakonas, S. (1997). Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 90, 281-291.
7. Blochlinger, K., Bodmer, R., Jan, L. Y. and Jan, Y. N. (1990). Patterns of expression of Cut, a protein required for external sensory organ development, in wild type and cut mutant embryos. Genes Dev. 4, 1322-1331.
8. Bodmer, R., Carretto, R. and Jan, Y. N. (1989). Neurogenesis of the peripheral nervous system in Drosophila embryos: DNA replication patterns and cell lineages. Neuron 3, 21-32.
9. Brewster, R. and Bodmer, R. (1995). Origin and specification of type II sensory neurons in Drosophila. Development 121, 2923-2936.
10. Broadus, J. and Doe, C. Q. (1997). Extrinsic cues, intrinsic cues, and microfilaments regulate asymmetric protein localization in Drosophila neuroblasts. Curr. Biol. 7, 827-835.
11. Campbell, G., Goring, H., Lin, T., Spana, E., Anderson, S., Doe, C. Q. and Tomlinson, A. (1994). RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila. Development 120, 2957-2966.
12. Campos-Ortega, J. A. (1995). Genetic mechanisms of early neurogenesis in Drosophila melanogaster. Mol. Neurobiol. 10, 75-89.
13. Cant, K., Knowles, B. A., Mooseker, M. S. and Cooley, L. (1994). Drosophila singed, a fascin homologue, is required for actin bundle formation during oogenesis and bristle extension. J. Cell Biol. 125, 369-380.
14. Chitnis, A., Henrique, D., Lewis, J., Ish-Horowics, D. and Kintner, C. (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375, 761-766.
15. Dambh-Chaudiere, C. and Ghysen, A. (1986). The sense organs in the Drosophila larva and their relation to the embryonic pattern of sensory neurons. Roux's Arch. Dev. Biol. 195, 222-228.
16. Doe, C. Q., Chu-Lagraff, Q., Wright, D. M. and Scott, M. P. (1991). The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 65, 451-464.
17. Fehon, R. G., Kooh, P. J., Rebay, I., Regan, C. L., Xu, T., Muskavitch, M. A. and Artavanis, T. S. (1990). Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61, 523-534.
18. FlyBase (1994). The Drosophila genetic database. Nucleic Acids Res. 3456-3458.
19. Fortini, M. E. and Artavanis-Tsakonas, S. (1994). The Suppressor of Hairless protein participates in Notch receptor signaling. Cell 79, 273-282.
20. Fortini, M. E., Rebay, I., Caron, L. A. and Artavanis-Tsakonas, S. (1993). An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365, 555-557.
21. r= 43,000 tropomyosin-binding protein from human erythrocyte membranes. J. Biol. Chem. 262, 12792-12800.
22. Frise, E., Knoblich, J. A., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N. (1996). The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interation in sensory organ lineage. Proc. Natl. Acad. Sci. USA 93, 11925-11932.
23. Gregorio, C. C., Weber, A., Bondad, M., Pennise, C. R. and Fowler, V. M. (1995). Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes. Nature 377, 83-86.
24. Guo, M., Jan, L. Y. and Jan, Y. N. (1996). Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17, 27-41.
25. Heitzler, P., and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1083-1092.
26. Higashijima, S., Michiue, T., Emori, Y. and Saigo, K. (1992). Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2. Genes Dev. 6, 1005-1018.
27. Hopmann, R., Cooper, J. A. and Miller, K. G. (1996). Actin organization, bristle morphology, and viability are affected by actin capping protein mutations in Drosophila. J. Cell Biol. 133, 1293-1305.
28. Horvitz, H. R. and Herskowitz, I. (1992). Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell 68, 237-255.
29. Hosoya, T., Takizawa, K., Nitta, K. and Hotta, Y. (1995). glial cells missing: a binary switch between neuronal and glial determination in Drosophila. Cell 82, 1025-1036.
30. Ingham, P. W., Taylor, A. M. and Nakano, Y. (1991). Role of the Drosophila patched gene in positional signalling. Nature 353, 184-187.
31. Ito, M., Swanson, B., Sussman, M. A., Kedes, L. and Lyons, G. (1995). Cloning of tropomodulin cDNA and localization of gene transcripts during mouse embryogenesis. Dev. Biol. 167, 317-328.
32. Jan, Y. N. and Jan, L. Y. (1995). Maggot's hair and bug's eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron 14, 1-5.
33. Jarriault, S., Brou, C., Logeat, F., Schroeter, E. H., Kopan, R. and Israel, A. (1995). Signalling downstream of activated mammalian Notch. Nature 377, 355-358.
34. Jones, B. W., Fetter, R. D., Tear, G. and Goodman, C. S. (1995). glial cells missing: A genetic switch that control glial versus neuronal fate. Cell 82, 1013-1023.
35. Kania, A., Salzberg, A., Bhat, M., D'Evelyn, D., He, Y., Kiss, I. and Bellen, H. J. (1995). P-element mutations affecting embryonic peripheral nervous system development in Drosophila melanogaster. Genetics 139, 1663-1678.
36. Kidd, S., Kelley, M. R. and Young, M. W. (1986). Sequence of the Notch locus of Drosophila melanogaster. relationship of the encoded protein to mammalian clotting and growth factors. Mol. Cell. Biol. 6, 3094-3108.
37. Klambt, C., Jacobs, J. R. and Goodman, C. S. (1991). The midline of the Drosophila central nervous system: a model genetic analysis of cell fate, cell migration, and growth cone guidance. Cell 64, 801-815.
38. Kopan, R., Schroeter, E. H., Weintraub, H. and Nye, J. S. (1996). Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain. Proc. Natn. Acad. Sci., USA 93, 1683-1688.
39. Kopan, R. and Turner, D. L. (1996). The Notch pathway: democracy and aristocracy in the selection of cell fate. Curr. Opin. Neurobiol. 6, 594-601.
40. Lecourtois, M. and Schweisguth, F. (1995). The neurogenic suppressor of Hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling. Genes Dev. 9, 2598-2608.
41. Lehmann, R., Dietrich, U., Jimenez, F. and Campos-Ortega, J. A. (1981). Mutations of early neurogenesis in Drosophila. Roux's Arch. Dev. Biol. 190, 226-229.
42. Lieber, T., Kidd, S., Alcamo, E., Corbin, V. and Young, M. W. (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7, 1949-1965.
43. Lu, F. M. and Lux, S. E. (1996). Constitutively active human Notch 1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element. Proc. Natl. Acad. Sci . USA 93, 5663-5667.
44. Pan, D. and Rubin, G. (1997). Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. Cell 90, 271-280.
45. Pirrotta, V. (1988). Vectors for P-element transformation in Drosophila. In Vectors. A Survey of Molecular Cloning Vectors and their Uses (ed. R. L.Rodriguez and D. T. Denhardt). Boston, Massachusetts: Butterworths.
46. Posakony, J. W. (1994). Nature versus nurture: asymmetric cell divisions in Drosophila bristle development . Cell 76, 415-418.
47. Rhyu, M. S., Jan, L. Y. and Jan, Y. N. (1994). Asymmetric distribution of Numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76, 477-491.
48. Rochl, H., Bosenberg, M., Blelloch, R. and Kimble, J. (1996). Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor. EMBO J. 15, 7002-7012.
49. Rooke, J., Pan, D., Xu, T. and Rubin, G. (1996). KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis. Science 273, 1227-1231.
50. Salzberg, A., D'Evelyn, D., Schulze, K. L., Lee, J.-K., Strumpf, D., Tsai, L. and Bellen, H. J. (1994). Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron 13, 269-287.
51. Salzberg, A., Prokopenko, S. N., He, Y.-C., Tsai, P., Maroy, P., Glover, D. M., Deak, P. and Bellen, H. J. (1997). P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: Mutations affecting embryonic PNS development. Genetics 147, 1723-1741.
52. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
53. Schweisguth, F. and Posakony, J. W. (1992). Suppressor of hairless, the Drosophila homolog of the mouse recombination signal binding protein gene, controls sensory organ cell fates. Cell 69, 1199-1212.
54. Schweisguth, F., Gho, M. and Lecourtois, M. (1996). Control of cell fate choices by lateral signaling in the adult peripheral nervous system of Drosophila melanogaster. Dev. Genetics 18, 28-39.
55. Skeath, J. B. and Doe, C. Q. (1997). Sanpodo and Notch act in opposition to Numb to mediate binary cell fate decisions. Development, 125, 1857-1865.
56. Spana, E. P. and Doe, C. Q. (1996). Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17, 21-26.
57. Strahl, G., Fitzgerald, K. and Greenwald, I. (1993). Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74, 331-345.
58. Sung, L. A., Fowler, V. M., Lambert, K., Sussman, M. A., Karr, D. and Chien, S. (1992). Molecular cloning and characterization of human fetal liver tropomodulin. J. Biol. Chem. 267, 2616-2621.
59. Uemura, T., Shepherd, S., Ackerman, L., Jan, L. Y. and Jan, Y. N. (1989). numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 5, 349-360.
60. Vaessin, H., Bremer, K. A., Knust, E. and Campos-Ortoga, J. A. (1987). The neurogenic gene Delta of Drosophila mekinogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats. EMBO J. 6, 3431-3440.
61. Vaessin, H., Grell, E., Wolff, E., Bier, E., Jan, L. Y. and Jan, Y. N. (1991). prospera is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell 67, 941-953.
62. Van Vactor, D., Sink, H., Fambrough, D., Tsoo, R. and Goodman, C. S. (1993). Genes that control neuromuscular specificity in Drosophila. Cell 73, 1137-1153.
63. Verheyen, E. M. and Cooley, L. (1994). Profilin mutations disrupt multipe actin dependent processes during Drosophila development. Development 120, 717-728.
64. Vervoort, M., Merritt, D. J., Ghysen, A. and Dambly-Chaudiere, C. (1997). Genetic basis of the formation and identity of type I and type II neurons in Drosophila embryos. Development 124, 2819-2828.
65. Vincent, S., Vonesch, J. L., and Giangrande, A. (1996). glide directs glial fate commitment and cell fate switch between neurones and glia. Development 122, 131-139.
66. Watakabe, A., Kobayashi, R. and Helfman, D. M. (1996). N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. J Cell Sci 109, 2299-2310.
67. Weber, A., Pennise, C. R., Babcock, G. C. and Fowler, V. M. (1994). Tropomodulin caps the pointed ends of actin filaments. J. Cell Biol. 127, 1627-1635.
68. Wettstein, D. A., Turner, D. L. and Kintner, C. (1997). The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development 124, 693-702.
69. Wharton, K. A., Johansen, K. M., Xu, T. and Artavanis-Tsakonas, S. (1985). Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell 43, 567-581.
70. Xiong, W.-C., Okano, H., Patel, N. H., Blendy, J. A. and Montell, C. (1991). repo encodes a glial-specified homeo domain protein required in the Drosophila nervous system. Genes Dev. 8, 981-994.
71. Zhang, P. and Spradling, A. C. (1993). Efficient and dispersed local P-element transposition from Drosophila females. Genetics 133, 361-373.
72. Zinn, K., McAllister, L. and Goodman, C. S. (1988). Sequence analysis and neuronal expression of fasciclin I in grasshopper and Drosophila. Cell 58, 577-587.