Bearded family members inhibit neuralized-mediated endocytosis and signaling activity of Delta in Drosophila

Developmental Cell

Volumn 10, Issue 2, 2006, Pages 245-255

  Bardin, Allison J ^a   Schweisguth, François ^a  

^a ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Cellbio; Devbio; Signaling

Indexed keywords

BEARDED PROTEIN; LIGAND; NOTCH RECEPTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; EMBRYO; ENDOCYTOSIS; GENE DELETION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TWO HYBRID SYSTEM;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY PATTERNING; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; ENDOCYTOSIS; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; LIGANDS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PHOSPHOPROTEINS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA;

EID: 31744445880     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.12.017     Document Type: Article

References (43)

1. Y. Apidianakis A.C. Nagel A. Chalkiadaki A. Preiss C. Delidakis Overexpression of the m4 and mα genes of the E(spl)-complex antagonizes notch mediated lateral inhibition Mech. Dev. 86 1999 39-50
2. Y. Bellaiche O. Beaudoin-Massiani I. Stuttem F. Schweisguth The planar cell polarity protein Strabismus promotes Pins anterior localization during asymmetric division of sensory organ precursor cells in Drosophila Development 131 2004 469-478
3. G.L. Boulianne A. de la Concha J.A. Campos-Ortega L.Y. Jan Y.N. Jan The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons EMBO J. 10 1991 2975-2983
4. B. Castro S. Barolo A.M. Bailey J.W. Posakony Lateral inhibition in proneural clusters: Cis-regulatory logic and default repression by Suppressor of Hairless Development 132 2005 3333-3344
5. J. Cowden M. Levine The Snail repressor positions Notch signaling in the Drosophila embryo Development 129 2002 1785-1793
6. G.A. Deblandre E.C. Lai C. Kintner Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling Dev. Cell 1 2001 795-806
7. M. Gho M. Lecourtois G. Geraud J.W. Posakony F. Schweisguth Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling Development 122 1996 1673-1682
8. L. Giot J.S. Bader C. Brouwer A. Chaudhuri B. Kuang Y. Li Y.L. Hao C.E. Ooi B. Godwin E. Vitols et al. A protein interaction map of Drosophila melanogaster Science 302 2003 1727-1736
9. M. Itoh C.H. Kim G. Palardy T. Oda Y.J. Jiang D. Maust S.Y. Yeo K. Lorick G.J. Wright L. Ariza-McNaughton et al. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta Dev. Cell 4 2003 67-82
10. E. Knust H. Schrons F. Grawe J.A. Campos-Ortega Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins Genetics 132 1992 505-518
11. M.G. Kolonin J. Zhong R.L. Finley Interaction mating methods in two-hybrid systems Methods Enzymol. 328 2000 26-46
12. B.K. Koo H.S. Lim R. Song M.J. Yoon K.J. Yoon J.S. Moon Y.W. Kim M.C. Kwon K.W. Yoo M.P. Kong et al. Mind bomb 1 is essential for generating functional Notch ligands to activate Notch Development 132 2005 3459-3470
13. B.K. Koo K.J. Yoon K.W. Yoo H.S. Lim R. Song J.H. So C.H. Kim Y.Y. Kong Mind bomb-2 is an E3 ligase for Notch ligand J. Biol. Chem. 280 2005 22335-22342
14. P.J. Kooh R.G. Fehon M.A. Muskavitch Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development Development 117 1993 493-507
15. E.C. Lai Notch signaling: Control of cell communication and cell fate Development 131 2004 965-973
16. E.C. Lai G.M. Rubin neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development Dev. Biol. 231 2001 217-233
17. E.C. Lai R. Bodner J. Kavaler G. Freschi J.W. Posakony Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes Development 127 2000 291-306
18. E.C. Lai R. Bodner J.W. Posakony The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family Development 127 2000 3441-3455
19. E.C. Lai G.A. Deblandre C. Kintner G.M. Rubin Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta Dev. Cell 1 2001 783-794
20. E.C. Lai F. Roegiers X. Qin Y.N. Jan G.M. Rubin The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta Development 132 2005 2319-2332
21. R. Le Borgne F. Schweisguth Unequal segregation of Neuralized biases Notch activation during asymmetric cell division Dev. Cell 5 2003 139-148
22. R. Le Borgne A. Bardin F. Schweisguth The roles of receptor and ligand endocytosis in regulating Notch signaling Development 132 2005 1751-1762
23. R. Le Borgne S. Remaud S. Hamel F. Schweisguth Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila PLoS Biol. 3 2005 e96
24. M.W. Leviten J.W. Posakony Gain-of-function alleles of Bearded interfere with alternative cell fate decisions in Drosophila adult sensory organ development Dev. Biol. 176 1996 264-283
25. M.W. Leviten E.C. Lai J.W. Posakony The Drosophila gene Bearded encodes a novel small protein and shares 3′ UTR sequence motifs with multiple Enhancer of split complex genes Development 124 1997 4039-4051
26. M.D. Martin-Bermudo A. Carmena F. Jimenez Neurogenic genes control gene expression at the transcriptional level in early neurogenesis and in mesectoderm specification Development 121 1995 219-224
27. V. Morel F. Schweisguth Repression by suppressor of hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo Genes Dev. 14 2000 377-388
28. V. Morel R. Le Borgne F. Schweisguth Snail is required for Delta endocytosis and Notch-dependent activation of single-minded expression Dev. Genes Evol. 213 2003 65-72
29. A.C. Nagel Y. Apidianakis I. Wech D. Maier C. Delidakis A. Preiss Neural hyperplasia induced by RNA interference with m4/mα gene activity Mech. Dev. 98 2000 19-28
30. J.R. Nambu R.G. Franks S. Hu S.T. Crews The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells Cell 63 1990 63-75
31. E. Pavlopoulos C. Pitsouli K.M. Klueg M.A. Muskavitch N.K. Moschonas C. Delidakis neuralized encodes a peripheral membrane protein involved in delta signaling and endocytosis Dev. Cell 1 2001 807-816
32. C. Pitsouli C. Delidakis The interplay between DSL proteins and ubiquitin ligases in Notch signaling Development 132 2005 4041-4050
33. J. Rusch M. Levine Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo Curr. Opin. Genet. Dev. 6 1996 416-423
34. F. Schweisguth Notch signaling activity Curr. Biol. 14 2004 R129-R138
35. A. Singson M.W. Leviten A.G. Bang X.H. Hua J.W. Posakony Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling Genes Dev. 8 1994 2058-2071
36. A. Stathopoulos M. Levine Genomic regulatory networks and animal development Dev. Cell 9 2005 449-462
37. T. Takeuchi Y. Adachi Y. Ohtsuki Skeletrophin, a novel ubiquitin ligase to the intracellular region of Jagged-2, is aberrantly expressed in multiple myeloma Am. J. Pathol. 166 2005 1817-1826
38. S.T. Thibault M.A. Singer W.Y. Miyazaki B. Milash N.A. Dompe C.M. Singh R. Buchholz M. Demsky R. Fawcett H.L. Francis-Lang et al. A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac Nat. Genet. 36 2004 283-287
39. W. Wang G. Struhl Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch Development 131 2004 5367-5380
40. W. Wang G. Struhl Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila Development 132 2005 2883-2894
41. E. Wurmbach I. Wech A. Preiss The Enhancer of split complex of Drosophila melanogaster harbors three classes of Notch responsive genes Mech. Dev. 80 1999 171-180
42. E. Yeh M. Dermer C. Commisso L. Zhou C.J. McGlade G.L. Boulianne Neuralized functions as an E3 ubiquitin ligase during Drosophila development Curr. Biol. 11 2001 1675-1679
43. S. Zaffran M. Frasch Barbu: An E(spl) m4/m(α)-related gene that antagonizes Notch signaling and is required for the establishment of ommatidial polarity Development 127 2000 1115-1130