DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

Journal of Cell Biology

Volumn 176, Issue 4, 2007, Pages 445-458

  Nichols, James T ^a   Miyamoto, Alison ^a   Olsen, Samantha L ^a   D'Souza, Brendan ^a   Yao, Christine ^a   Weinmaster, Gerry ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; DELTA SERRATE LAG 2 LIGAND; HETERODIMER; LIGAND; NOTCH1 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISSOCIATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TRANSPORT;

ADAM PROTEINS; ANIMALS; CELL LINE; CELL MEMBRANE; DIMERIZATION; ENDOCYTOSIS; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MICE; MODELS, MOLECULAR; PEPTIDE HYDROLASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION;

EID: 33846968807     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200609014     Document Type: Article

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