Vitamin E analogs, a novel group of "mitocans," as anticancer agents: The importance of being redox-silent

Molecular Pharmacology

Volumn 71, Issue 5, 2007, Pages 1185-1199

  Neuzil, Jiri ^a,b   Tomasetti, Marco ^d   Zhao, Yan ^c   Dong, Lan Feng ^a   Birringer, Marc ^e   Wang, Xiu Fang ^a   Low, Pauline ^a   Wu, Kun ^c   Salvatore, Brian A ^f   Ralph, Steven J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c HARBIN MEDICAL UNIVERSITY   (China)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^e FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^f LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ACETYLCYSTEINE; ALITRETINOIN; ALPHA TOCOPHEROL; ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHEROL SUCCINATE; ALPHA TOCOPHERYL FUMARATE; ALPHA TOCOPHERYL MALEATE; ALPHA TOCOTRIENOL; ANTIMYCIN A1; ANTINEOPLASTIC AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; ARSENIC DERIVATIVE; CISPLATIN; DELTA TOCOTRIENOL; DEOXYGLUCOSE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; GAMMA TOCOTRIENOL; LONIDAMINE; METHOTREXATE; OXAMIC ACID; RETINOIC ACID; TAMOXIFEN; TOCOPHEROL; TROLOX C; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; BREAST CARCINOMA; CANCER; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; COLON CANCER; COLORECTAL CARCINOMA; COMBINATION CHEMOTHERAPY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG HALF LIFE; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; HEMATOLOGIC MALIGNANCY; HUMAN; HYPOGLYCEMIA; MELANOMA; MESOTHELIOMA; MITOCHONDRION; MULTIPLE MYELOMA; MYELODYSPLASTIC SYNDROME; NEUROTOXICITY; NONHUMAN; OSTEOSARCOMA; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; SHORT SURVEY; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; SOLID TUMOR; STRUCTURE ACTIVITY RELATION; UNSPECIFIED SIDE EFFECT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; HUMANS; MITOCHONDRIA; OXIDATION-REDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; VITAMIN E;

EID: 34247511558     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.030122     Document Type: Short Survey

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