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Volumn 127, Issue 5, 1997, Pages 668-674

Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A reductase; mice; monoterpenes; tocotrienols; tumor implants

Indexed keywords

ALPHA TOCOTRIENOL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOPRENOID; TERPENE DERIVATIVE;

EID: 0030950694     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/127.5.668     Document Type: Article
Times cited : (261)

References (39)
  • 1
    • 0028289655 scopus 로고
    • Differences in sensitivity to farnesol toxicity between neoplasically-and non-neoplastically-derived cells in culture
    • Adany, I., Yazlovitskaya, E. M., Haug, J. S., Voziyan, P. A. & Melnykovych, G. (1994) Differences in sensitivity to farnesol toxicity between neoplasically-and non-neoplastically-derived cells in culture. Cancer Lett. 79: 175-179.
    • (1994) Cancer Lett. , vol.79 , pp. 175-179
    • Adany, I.1    Yazlovitskaya, E.M.2    Haug, J.S.3    Voziyan, P.A.4    Melnykovych, G.5
  • 2
    • 0017375321 scopus 로고
    • Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies
    • American Institute of Nutrition (1977) Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies. J. Nutr. 107: 1340-1348.
    • (1977) J. Nutr. , vol.107 , pp. 1340-1348
  • 3
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
    • Block, G., Patterson, B. & Subar, A. (1992) Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr. Cancer 18: 1-29.
    • (1992) Nutr. Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 4
    • 0026589729 scopus 로고
    • Hypomethylation of β-hydroxy-β-methylglutaryl coenzyme A reductase gene and its expression during hepatocarcinogenesis in the rat
    • Coni, P., Pang, J., Pichiri-Coni, G., Hsu, S., Rao, P. M., Rajalakshimi, S. & Sarma, D.S.R. (1992) Hypomethylation of β-hydroxy-β-methylglutaryl coenzyme A reductase gene and its expression during hepatocarcinogenesis in the rat. Carcinogenesis 13: 497-499.
    • (1992) Carcinogenesis , vol.13 , pp. 497-499
    • Coni, P.1    Pang, J.2    Pichiri-Coni, G.3    Hsu, S.4    Rao, P.M.5    Rajalakshimi, S.6    Sarma, D.S.R.7
  • 5
    • 0028307290 scopus 로고
    • Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase
    • Correll, C. C., Ng, L. & Edwards, P. A. (1994) Identification of farnesol as the non-sterol derivative of mevalonic acid required for the accelerated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J. Biol. Chem. 269: 17390-17393.
    • (1994) J. Biol. Chem. , vol.269 , pp. 17390-17393
    • Correll, C.C.1    Ng, L.2    Edwards, P.A.3
  • 6
    • 0029455887 scopus 로고
    • Hypomethylation of DNA: A possible epigenetic mechanism involved in tumor promotion
    • Counts, J. L. & Goodman, J. I. (1995) Hypomethylation of DNA: a possible epigenetic mechanism involved in tumor promotion. Prog. Clin. Biol. Res. 391: 81-101.
    • (1995) Prog. Clin. Biol. Res. , vol.391 , pp. 81-101
    • Counts, J.L.1    Goodman, J.I.2
  • 7
    • 0001385198 scopus 로고
    • Biosynthesis of sesquiterpenes
    • Porter, J. W. & Spurgeon, S. L., eds. John Wiley & Sons, New York, NY
    • Crane, D. (1981) Biosynthesis of sesquiterpenes. In: Biosynthesis of Isoprenoid Compounds (Porter, J. W. & Spurgeon, S. L., eds.), vol. 1, pp. 283-374. John Wiley & Sons, New York, NY.
    • (1981) Biosynthesis of Isoprenoid Compounds , vol.1 , pp. 283-374
    • Crane, D.1
  • 8
    • 0000261787 scopus 로고
    • Biosynthesis of monoterpenes
    • Porter, J. W. & Spurgeon, S. L., eds. John Wiley & Sons, New York, NY
    • Croteau, R. (1981) Biosynthesis of monoterpenes. In: Biosynthesis of Isoprenoid Compounds (Porter, J. W. & Spurgeon, S. L., eds.), vol. 1, pp. 225-282. John Wiley & Sons, New York, NY.
    • (1981) Biosynthesis of Isoprenoid Compounds , vol.1 , pp. 225-282
    • Croteau, R.1
  • 9
    • 0025952954 scopus 로고
    • Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites
    • Crowell, P. L., Chang, R. R., Ren, Z., Elson, C. E. & Gould, M. N. (1991) Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites. J. Biol. Chem. 266: 17679-17685.
    • (1991) J. Biol. Chem. , vol.266 , pp. 17679-17685
    • Crowell, P.L.1    Chang, R.R.2    Ren, Z.3    Elson, C.E.4    Gould, M.N.5
  • 10
    • 0028959503 scopus 로고
    • Suppression of the proliferation of rastransformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism
    • Cuthbert, J. A. & Lipsky, P. E. (1995) Suppression of the proliferation of rastransformed cells by fluoromevalonate, an inhibitor of mevalonate metabolism. Cancer Res. 55: 1732-1740.
    • (1995) Cancer Res. , vol.55 , pp. 1732-1740
    • Cuthbert, J.A.1    Lipsky, P.E.2
  • 11
    • 0026057240 scopus 로고
    • Inhibition of cell growth by lovastatin is independent of ras function
    • DeClue, J. E., Vass, W. C., Papageorge, A. G., Lowy, D. R. & Willumsen, B. M. (1991) Inhibition of cell growth by lovastatin is independent of ras function. Cancer Res. 51: 712-717.
    • (1991) Cancer Res. , vol.51 , pp. 712-717
    • DeClue, J.E.1    Vass, W.C.2    Papageorge, A.G.3    Lowy, D.R.4    Willumsen, B.M.5
  • 12
    • 0029048924 scopus 로고
    • Suppression of mevalonate pathway activities by dietary isoprenoids: Protective roles in cancer and cardiovascular disease
    • Elson, C.E. (1995) Suppression of mevalonate pathway activities by dietary isoprenoids: protective roles in cancer and cardiovascular disease. J. Nutr. 125: 1666S-1672S.
    • (1995) J. Nutr. , vol.125
    • Elson, C.E.1
  • 13
    • 0028861784 scopus 로고
    • Coupling the cholesterol-and tumor-suppressive actions of palm oil to the impact of its minor constituents on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
    • Elson, C. E. & Qureshi, A. A. (1995) Coupling the cholesterol-and tumor-suppressive actions of palm oil to the impact of its minor constituents on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Prost. Leuko. Essen. Fatty Acid 52: 205-208.
    • (1995) Prost. Leuko. Essen. Fatty Acid , vol.52 , pp. 205-208
    • Elson, C.E.1    Qureshi, A.A.2
  • 14
    • 0028245392 scopus 로고
    • The chemoprevention of cancer by mevalonate-derived constituents of fruits and vegetables
    • Elson, C. E. & Yu, S. G. (1994) The chemoprevention of cancer by mevalonate-derived constituents of fruits and vegetables. J. Nutr. 124: 607-614.
    • (1994) J. Nutr. , vol.124 , pp. 607-614
    • Elson, C.E.1    Yu, S.G.2
  • 15
    • 0029455962 scopus 로고
    • Prevention and therapy of mammary cancer by monoterpenes
    • Gould, M. N. (1995) Prevention and therapy of mammary cancer by monoterpenes. J. Cell. Biochem. S22: 139-144.
    • (1995) J. Cell. Biochem. , vol.S22 , pp. 139-144
    • Gould, M.N.1
  • 16
    • 0029919323 scopus 로고    scopus 로고
    • Antioxidant vitamins, cancer and cardiovascular disease
    • Greenberg, E. R. & Sporn, M. B. (1996) Antioxidant vitamins, cancer and cardiovascular disease. N. Engl. J. Med. 334: 1189-1190.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1189-1190
    • Greenberg, E.R.1    Sporn, M.B.2
  • 17
    • 0026623497 scopus 로고
    • Increased expression of protein kinase C alpha plays a key role in retinoic acid-induced melanoma differentiation
    • Gruber, J. R., Ohno, S. & Niles, R. M. (1992) Increased expression of protein kinase C alpha plays a key role in retinoic acid-induced melanoma differentiation. J. Biol. Chem. 267: 13356-13360.
    • (1992) J. Biol. Chem. , vol.267 , pp. 13356-13360
    • Gruber, J.R.1    Ohno, S.2    Niles, R.M.3
  • 19
    • 0030015296 scopus 로고    scopus 로고
    • The chemistry and antioxidant properties of tocopherols and tocotrienols
    • Kamal-Eldin, A. & Appelqvist, L.-A. (1996) The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids 31: 671-701.
    • (1996) Lipids , vol.31 , pp. 671-701
    • Kamal-Eldin, A.1    Appelqvist, L.-A.2
  • 20
    • 0025291799 scopus 로고
    • Increase in the active form of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human hepatocellular carcinoma: Possible mechanism for alteration of cholesterol biosynthesis
    • Kawata, S., Takaishi, K., Nagase, T., Ito, N., Matsuda, Y., Tamura, S., Matsuzawa, Y. & Tarui, S. (1990) Increase in the active form of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human hepatocellular carcinoma: possible mechanism for alteration of cholesterol biosynthesis. Cancer Res. 50: 3270-3273.
    • (1990) Cancer Res. , vol.50 , pp. 3270-3273
    • Kawata, S.1    Takaishi, K.2    Nagase, T.3    Ito, N.4    Matsuda, Y.5    Tamura, S.6    Matsuzawa, Y.7    Tarui, S.8
  • 21
    • 0028346953 scopus 로고
    • Progress in cancer prevention: Perspectives on agent selection and short-term intervention trials
    • Kelloff, G. J., Boone, C. W., Steele, V. E., Crowell, J. A., Lubet, R. & Sigman, C. C. (1994) Progress in cancer prevention: perspectives on agent selection and short-term intervention trials. Cancer Res. 54: 2015s-2024s.
    • (1994) Cancer Res. , vol.54
    • Kelloff, G.J.1    Boone, C.W.2    Steele, V.E.3    Crowell, J.A.4    Lubet, R.5    Sigman, C.C.6
  • 22
    • 0029074787 scopus 로고
    • Development of inhibitors of protein farnesylation as potential chemotherapeutic agents
    • Kohl, N. E., Conner, M. W., Gibbs, J. B., Graham, S. L., Hartman, G. D. & Oliff, A. (1995) Development of inhibitors of protein farnesylation as potential chemotherapeutic agents. J. Cell. Biochem. 22: 145-150.
    • (1995) J. Cell. Biochem. , vol.22 , pp. 145-150
    • Kohl, N.E.1    Conner, M.W.2    Gibbs, J.B.3    Graham, S.L.4    Hartman, G.D.5    Oliff, A.6
  • 24
    • 0025035766 scopus 로고
    • Responses of a murine B16 melanoma to pharmacotherapy studied and compared with different assay systems
    • Kuwashima, Y., Matsubara, O. & Kasuga, T. (1990) Responses of a murine B16 melanoma to pharmacotherapy studied and compared with different assay systems. Cancer Res. Clin. Oncol. 116: 173-178.
    • (1990) Cancer Res. Clin. Oncol. , vol.116 , pp. 173-178
    • Kuwashima, Y.1    Matsubara, O.2    Kasuga, T.3
  • 25
    • 0028074299 scopus 로고
    • DNA methylation and cancer
    • Laird, P. W. & Jaenisch, R. (1994) DNA methylation and cancer. Human Mol. Genet. 3: 1487-1495.
    • (1994) Human Mol. Genet. , vol.3 , pp. 1487-1495
    • Laird, P.W.1    Jaenisch, R.2
  • 27
    • 0025885468 scopus 로고
    • Ascorbate in the treatment of experimental transplanted melanoma
    • Meadows, G. G., Pierson, H. F. & Abdallah, R. (1991) Ascorbate in the treatment of experimental transplanted melanoma. Am. J. Clin. Nutr. 54: 1284s-1291s.
    • (1991) Am. J. Clin. Nutr. , vol.54
    • Meadows, G.G.1    Pierson, H.F.2    Abdallah, R.3
  • 28
    • 0029969302 scopus 로고    scopus 로고
    • Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A degradation by the nonsterol mevalonate farnesol in vivo
    • Meigs, T.E., Roseman, D. S. & Simoni, R. D. (1996). Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A degradation by the nonsterol mevalonate farnesol in vivo. J. Biol. Chem. 271: 7916-7922.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7916-7922
    • Meigs, T.E.1    Roseman, D.S.2    Simoni, R.D.3
  • 29
    • 0027288196 scopus 로고
    • Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
    • Parker, R. A., Pearce, B. C., Clark, R. W., Gordan, D. A. & Wright, J J.K. (1993) Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. J. Biol. Chem. 268: 11230-11238.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11230-11238
    • Parker, R.A.1    Pearce, B.C.2    Clark, R.W.3    Gordan, D.A.4    Wright, J.J.K.5
  • 30
    • 0028307941 scopus 로고
    • Inhibition of isoprenoid biosynthesis induces apoptosis in human promylocytic HL-60 cells
    • Perez-Sala, D. & Mollinedo, F. (1994) Inhibition of isoprenoid biosynthesis induces apoptosis in human promylocytic HL-60 cells. Biochem. Biophys. Res. Commun. 199: 1209-1215.
    • (1994) Biochem. Biophys. Res. Commun. , vol.199 , pp. 1209-1215
    • Perez-Sala, D.1    Mollinedo, F.2
  • 32
    • 0027934698 scopus 로고
    • Similar patterns of hypomethylation in the β-hydroxy-β-methylglutaryl coenzyme A reductase gene in hepatic nodules induced by different carcinogens
    • Rossiello, M. R., Rao, P. M., Rajalakshmi, S. & Sarma, D.S.R. (1994) Similar patterns of hypomethylation in the β-hydroxy-β-methylglutaryl coenzyme A reductase gene in hepatic nodules induced by different carcinogens. Mol. Carcinogenesis 10: 237-245.
    • (1994) Mol. Carcinogenesis , vol.10 , pp. 237-245
    • Rossiello, M.R.1    Rao, P.M.2    Rajalakshmi, S.3    Sarma, D.S.R.4
  • 33
    • 0026027665 scopus 로고
    • Concentrationdependent increase in murine P388 and B16 population doubling time by the acyclic monoterpene geraniol
    • Shoff, S. M., Grummer M., Yatvin, M. B. & Elson, C. E. (1991) Concentrationdependent increase in murine P388 and B16 population doubling time by the acyclic monoterpene geraniol. Cancer Res. 51: 37-42.
    • (1991) Cancer Res. , vol.51 , pp. 37-42
    • Shoff, S.M.1    Grummer, M.2    Yatvin, M.B.3    Elson, C.E.4
  • 36
    • 0026247761 scopus 로고
    • Malignant melanoma: Relationship to parameters of differentiation
    • Tsukamoto, K., Gersten, D. M., Law, L. W. & Hearing, V. J. (1991) Malignant melanoma: relationship to parameters of differentiation. Melanoma Res. 1: 223-230.
    • (1991) Melanoma Res. , vol.1 , pp. 223-230
    • Tsukamoto, K.1    Gersten, D.M.2    Law, L.W.3    Hearing, V.J.4
  • 38
    • 0000013248 scopus 로고
    • Biosynthesis of diterpenes
    • Porter, J. W. & Spurgeon, S. L., eds. John Wiley & Sons, New York, NY
    • West, C. (1981) Biosynthesis of diterpenes. In: Biosynthesis of Isoprenoid Compounds (Porter, J. W. & Spurgeon, S. L., eds.), vol. 1, pp. 375-411. John Wiley & Sons, New York, NY.
    • (1981) Biosynthesis of Isoprenoid Compounds , vol.1 , pp. 375-411
    • West, C.1
  • 39
    • 0028843982 scopus 로고
    • Geraniol, an inhibitor of mevalonate biosynthesis, suppresses the growth of hepatomas and melanomas transplanted to rats and mice
    • Yu, S. G., Hildebrandt, L. A. & Elson, C. E. (1995) Geraniol, an inhibitor of mevalonate biosynthesis, suppresses the growth of hepatomas and melanomas transplanted to rats and mice. J. Nutr. 125: 2763-2767.
    • (1995) J. Nutr. , vol.125 , pp. 2763-2767
    • Yu, S.G.1    Hildebrandt, L.A.2    Elson, C.E.3


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