Structural basis for the quinone reduction in the bc1 complex: A comparative analysis of crystal structures of mitochondrial cytochrome bc1 with bound substrate and inhibitors at the Qi site

Biochemistry

Volumn 42, Issue 30, 2003, Pages 9067-9080

  Gao, Xiugong ^a   Wen, Xiaoling ^b   Esser, Lothar ^a   Quinn, Byron ^b   Yu, Linda ^b   Yu, Chang An ^b   Xia, Di ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CONFORMATIONS; CRYSTAL STRUCTURE; PROTEINS; REDUCTION;

MEMBRANE PROTEINS;

BIOCHEMISTRY;

1,4 BENZOQUINONE; 2 NONYL 4 QUINOLINOL N OXIDE; ANTIMYCIN A1; ASPARTIC ACID; ENZYME INHIBITOR; HISTIDINE; IRON SULFUR PROTEIN; LYSINE; MITOCHONDRIAL ENZYME; STIGMATELLIN; UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CATALYSIS; CELL RESPIRATION; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON TRANSPORT; ENZYME INHIBITOR INTERACTION; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PHENOTYPE; PHOTOSYNTHESIS; PRIORITY JOURNAL; PROTON TRANSPORT; REDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIMYCIN A; BENZOQUINONES; CATTLE; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME B GROUP; ELECTRON TRANSPORT COMPLEX III; ENZYME INHIBITORS; HYDROXYQUINOLINES; MITOCHONDRIA, HEART; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; UBIQUINONE;

ANIMALIA; BOVINAE;

EID: 0043167790     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0341814     Document Type: Article

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