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Volumn 4, Issue 1, 2005, Pages 43-50

Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by α-tocopheryl succinate in human prostate cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; BIM PROTEIN; CASPASE 9; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; ONCOPROTEIN; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE;

EID: 13944274587     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (69)

References (41)
  • 1
    • 0021016750 scopus 로고
    • Study on the specificity of α-tocopheryl (vitamin E) acid succinate effects on melanoma, glioma and neuroblastoma cells in culture
    • Rama BN, Prasad KN. Study on the specificity of α-tocopheryl (vitamin E) acid succinate effects on melanoma, glioma and neuroblastoma cells in culture. Proc Soc Exp Biol Med 1983;174:302-7.
    • (1983) Proc. Soc. Exp. Biol. Med. , vol.174 , pp. 302-307
    • Rama, B.N.1    Prasad, K.N.2
  • 2
    • 0020080829 scopus 로고
    • Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture
    • Prasad KN, Edwards-Prasad J. Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture. Cancer Res 1982;42:550-5.
    • (1982) Cancer Res. , vol.42 , pp. 550-555
    • Prasad, K.N.1    Edwards-Prasad, J.2
  • 3
    • 0033043778 scopus 로고    scopus 로고
    • Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols
    • Yu W, Simmons-Menchaca M, Gapor A, Sanders BG, Kline K. Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. Nutr Cancer 1999;33:26-32.
    • (1999) Nutr. Cancer , vol.33 , pp. 26-32
    • Yu, W.1    Simmons-Menchaca, M.2    Gapor, A.3    Sanders, B.G.4    Kline, K.5
  • 4
    • 0036301439 scopus 로고    scopus 로고
    • Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo
    • Weber T, Lu M, Anders L, et al. Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo. Clin Cancer Res 2002;8:863-9.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 863-869
    • Weber, T.1    Lu, M.2    Anders, L.3
  • 6
    • 0348013451 scopus 로고    scopus 로고
    • Vitamin E succinate and cancer treatment: A vitamin E prototype for selective antitumour activity
    • Neuzil J. Vitamin E succinate and cancer treatment: a vitamin E prototype for selective antitumour activity. Br J Cancer 2003;89: 1822-6.
    • (2003) Br. J. Cancer , vol.89 , pp. 1822-1826
    • Neuzil, J.1
  • 7
    • 0037387334 scopus 로고    scopus 로고
    • α-Tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: A review
    • Prasad KN, Kumar B, Yan XD, Hanson AJ, Cole WC. α-Tocopheryl succinate, the most effective form of vitamin E for adjuvant cancer treatment: a review. J Am Coll Nutr 2003;22:108-17.
    • (2003) J. Am. Coll. Nutr. , vol.22 , pp. 108-117
    • Prasad, K.N.1    Kumar, B.2    Yan, X.D.3    Hanson, A.J.4    Cole, W.C.5
  • 8
    • 0029094042 scopus 로고
    • RRR-α-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle/differentiation pathways
    • Israel K, Sanders BG, Kline K. RRR-α-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle/differentiation pathways. Nutr Cancer 1995;24:161-9.
    • (1995) Nutr. Cancer , vol.24 , pp. 161-169
    • Israel, K.1    Sanders, B.G.2    Kline, K.3
  • 9
    • 0034074981 scopus 로고    scopus 로고
    • Vitamin E succinate induces apoptosis in human prostate cancer cells: Role for Fas in vitamin E succinate-triggered apoptosis
    • Israel K, Yu W, Sanders BG, Kline K. Vitamin E succinate induces apoptosis in human prostate cancer cells: role for Fas in vitamin E succinate-triggered apoptosis. Nutr Cancer 2000;36:90-100.
    • (2000) Nutr. Cancer , vol.36 , pp. 90-100
    • Israel, K.1    Yu, W.2    Sanders, B.G.3    Kline, K.4
  • 10
    • 0037427539 scopus 로고    scopus 로고
    • Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery
    • Ni J, Chen M, Zhang Y, Li R, Huang J, Yeh S. Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery. Biochem Biophys Res Commun 2003;300:357-63.
    • (2003) Biochem. Biophys. Res. Commun. , vol.300 , pp. 357-363
    • Ni, J.1    Chen, M.2    Zhang, Y.3    Li, R.4    Huang, J.5    Yeh, S.6
  • 11
    • 0029129409 scopus 로고
    • RRR-α-tocopheryl succinate inhibits DNA synthesis and enhances the production and secretion of biologically active transforming growth factor-β by avian retrovirus-transformed lymphoid cells
    • Simmons-Menchaca M, Qian M, Yu W, Sanders BG, Kline K. RRR-α-tocopheryl succinate inhibits DNA synthesis and enhances the production and secretion of biologically active transforming growth factor-β by avian retrovirus-transformed lymphoid cells. Nutr Cancer 1995;24:171-85.
    • (1995) Nutr. Cancer , vol.24 , pp. 171-185
    • Simmons-Menchaca, M.1    Qian, M.2    Yu, W.3    Sanders, B.G.4    Kline, K.5
  • 12
    • 0034799471 scopus 로고    scopus 로고
    • RRR-α-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation
    • You H, Yu W, Sanders BG, Kline K. RRR-α-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation. Cell Growth Differ 2001;12:471-80.
    • (2001) Cell Growth Differ. , vol.12 , pp. 471-480
    • You, H.1    Yu, W.2    Sanders, B.G.3    Kline, K.4
  • 13
    • 0036968662 scopus 로고    scopus 로고
    • RRR-α-tocopheryl succinate induction of DNA synthesis arrest of human MDA-MB-435 cells involves TGF-β-independent activation of p21Waf1/Cip1
    • Yu W, Sanders BG, Kline K. RRR-α-tocopheryl succinate induction of DNA synthesis arrest of human MDA-MB-435 cells involves TGF-β-independent activation of p21Waf1/Cip1. Nutr Cancer 2002;43:227-36.
    • (2002) Nutr. Cancer , vol.43 , pp. 227-236
    • Yu, W.1    Sanders, B.G.2    Kline, K.3
  • 14
    • 0037188486 scopus 로고    scopus 로고
    • Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells
    • Zhang Y, Ni J, Messing EM, Chang E, Yang CR, Yeh S. Vitamin E succinate inhibits the function of androgen receptor and the expression of prostate-specific antigen in prostate cancer cells. Proc Natl Acad Sci U S A 2002;99:7408-13.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 7408-7413
    • Zhang, Y.1    Ni, J.2    Messing, E.M.3    Chang, E.4    Yang, C.R.5    Yeh, S.6
  • 15
    • 0142219868 scopus 로고    scopus 로고
    • Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells
    • Zu K, Ip C. Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells. Cancer Res 2003;63:6988-95.
    • (2003) Cancer Res. , vol.63 , pp. 6988-6995
    • Zu, K.1    Ip, C.2
  • 17
    • 0038481271 scopus 로고    scopus 로고
    • Mitochondrial regulation of apoptosis
    • Mayer B, Oberbauer R. Mitochondrial regulation of apoptosis. News Physiol Sci 2003;18:89-94.
    • (2003) News Physiol. Sci. , vol.18 , pp. 89-94
    • Mayer, B.1    Oberbauer, R.2
  • 18
    • 0037401562 scopus 로고    scopus 로고
    • Cell death regulation by the Bcl-2 protein family in the mitochondria
    • Tsujimoto Y. Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol 2003;195:158-67.
    • (2003) J. Cell Physiol. , vol.195 , pp. 158-167
    • Tsujimoto, Y.1
  • 19
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999;13:1899-911.
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 20
    • 0038520017 scopus 로고    scopus 로고
    • RRR-α-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Sax translocation to mitochondria
    • Yu W, Sanders BG, Kline K. RRR-α-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Sax translocation to mitochondria. Cancer Res 2003;63:2483-91.
    • (2003) Cancer Res. , vol.63 , pp. 2483-2491
    • Yu, W.1    Sanders, B.G.2    Kline, K.3
  • 21
    • 0345103741 scopus 로고    scopus 로고
    • Mitochondria play a central role in apoptosis induced by α-tocopheryl succinate, an agent with antineoplastic activity: Comparison with receptor-mediated pro-apoptotic signaling
    • Weber T, Dalen H, Andera L, et al. Mitochondria play a central role in apoptosis induced by α-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling. Biochemistry 2003;42:4277-91.
    • (2003) Biochemistry , vol.42 , pp. 4277-4291
    • Weber, T.1    Dalen, H.2    Andera, L.3
  • 22
    • 0033052252 scopus 로고    scopus 로고
    • α-Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation
    • Neuzil J, Svensson I, Weber T, Weber C, Brunk UT. α-Tocopheryl succinate-induced apoptosis in Jurkat T cells involves caspase-3 activation, and both lysosomal and mitochondrial destabilisation. FEBS Lett 1999;445:295-300.
    • (1999) FEBS Lett. , vol.445 , pp. 295-300
    • Neuzil, J.1    Svensson, I.2    Weber, T.3    Weber, C.4    Brunk, U.T.5
  • 23
    • 0037224465 scopus 로고    scopus 로고
    • Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array
    • Dong Y, Zhang H, Hawthorn L, Ganther HE, Ip C. Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. Cancer Res 2003;63:52-9.
    • (2003) Cancer Res. , vol.63 , pp. 52-59
    • Dong, Y.1    Zhang, H.2    Hawthorn, L.3    Ganther, H.E.4    Ip, C.5
  • 25
    • 0037860975 scopus 로고    scopus 로고
    • JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
    • Putcha GV, Le S, Frank S, et al. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 2003;38:899-914.
    • (2003) Neuron , vol.38 , pp. 899-914
    • Putcha, G.V.1    Le, S.2    Frank, S.3
  • 26
    • 17744376942 scopus 로고    scopus 로고
    • Induction of cancer cell apoptosis by α-tocopheryl succinate: Molecular pathways and structural requirements
    • Neuzil J, Weber T, Schroder A, et al. Induction of cancer cell apoptosis by α-tocopheryl succinate: molecular pathways and structural requirements. FASEB J 2001; 15:403-15.
    • (2001) FASEB J. , vol.15 , pp. 403-415
    • Neuzil, J.1    Weber, T.2    Schroder, A.3
  • 27
    • 0029954102 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase
    • Wang XS, Diener K, Jannuzzi D, et al. Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase. J Biol Chem 1996;271:31607-11.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31607-31611
    • Wang, X.S.1    Diener, K.2    Jannuzzi, D.3
  • 28
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
    • Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997;275:90-4.
    • (1997) Science , vol.275 , pp. 90-94
    • Ichijo, H.1    Nishida, E.2    Irie, K.3
  • 30
    • 0032514967 scopus 로고    scopus 로고
    • A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
    • Takekawa M, Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell 1998;95:521-30.
    • (1998) Cell , vol.95 , pp. 521-530
    • Takekawa, M.1    Saito, H.2
  • 31
    • 0036275374 scopus 로고    scopus 로고
    • Regulation of MTK1 /MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding
    • Mita H, Tsutsui J, Takekawa M, Witten EA, Saito H. Regulation of MTK1 /MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding. Mol Cell Biol 2002;22:4544-55.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 4544-4555
    • Mita, H.1    Tsutsui, J.2    Takekawa, M.3    Witten, E.A.4    Saito, H.5
  • 32
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-52.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 33
    • 0031883140 scopus 로고    scopus 로고
    • The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression
    • Faris M, Kokot N, Latinis K, et al. The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression. J Immunol 1998;160:134-44.
    • (1998) J. Immunol. , vol.160 , pp. 134-144
    • Faris, M.1    Kokot, N.2    Latinis, K.3
  • 34
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei K, Davis RJ. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 2003;100:2432-7.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 35
    • 15644381250 scopus 로고    scopus 로고
    • Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1
    • Maundrell K, Antonsson B, Magnenat E, et al. Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1. J Biol Chem 1997;272:25238-42.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25238-25242
    • Maundrell, K.1    Antonsson, B.2    Magnenat, E.3
  • 36
    • 0033499801 scopus 로고    scopus 로고
    • BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M
    • Yamamoto K, Ichijo H, Korsmeyer SJ. BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol 1999;19:8469-78.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 8469-8478
    • Yamamoto, K.1    Ichijo, H.2    Korsmeyer, S.J.3
  • 37
    • 0034059440 scopus 로고    scopus 로고
    • Bcl-2 inhibits Sax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
    • Murphy KM, Ranganathan V, Farnsworth ML, Kavallaris M, Lock RB. Bcl-2 inhibits Sax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. Cell Death Differ 2000;7: 102-11.
    • (2000) Cell Death Differ. , vol.7 , pp. 102-111
    • Murphy, K.M.1    Ranganathan, V.2    Farnsworth, M.L.3    Kavallaris, M.4    Lock, R.B.5
  • 38
    • 0034625352 scopus 로고    scopus 로고
    • Scl-2 inhibits a Fas-induced conformational change in the Sax N terminus and Sax mitochondrial translocation
    • Murphy KM, Streips UN, Lock RB. Scl-2 inhibits a Fas-induced conformational change in the Sax N terminus and Sax mitochondrial translocation. J Biol Chem 2000;275:17226-8.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17226-17228
    • Murphy, K.M.1    Streips, U.N.2    Lock, R.B.3
  • 39
    • 0035851204 scopus 로고    scopus 로고
    • BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Sax to induce apoptosis in neurons
    • Harris CA, Johnson EM Jr. BH3-only Bcl-2 family members are coordinately regulated by the JNK pathway and require Sax to induce apoptosis in neurons. J Biol Chem 2001;276:37754-60.
    • (2001) J. Biol. Chem. , vol.276 , pp. 37754-37760
    • Harris, C.A.1    Johnson Jr., E.M.2
  • 40
    • 0036269755 scopus 로고    scopus 로고
    • The Sax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase
    • Lei K, Nimnual A, Zong WX, et al. The Sax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Mol Cell Biol 2002;22:4929-42.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 4929-4942
    • Lei, K.1    Nimnual, A.2    Zong, W.X.3
  • 41
    • 0042220409 scopus 로고    scopus 로고
    • The structure of a Bcl-xL/Sim fragment complex: Implications for Sim function
    • Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Sim fragment complex: implications for Sim function. Immunity 2003;19:341-52.
    • (2003) Immunity , vol.19 , pp. 341-352
    • Liu, X.1    Dai, S.2    Zhu, Y.3    Marrack, P.4    Kappler, J.W.5


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