-
1
-
-
0024160877
-
Banting lecture 1988. Role of insulin resistance in human disease
-
Reaven GM (1988) Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 37:1595-1607
-
(1988)
Diabetes
, vol.37
, pp. 1595-1607
-
-
Reaven, G.M.1
-
2
-
-
0036615436
-
Molecular insights into insulin action and secretion
-
Rhodes CJ, White MF (2002) Molecular insights into insulin action and secretion. Eur J Clin Investig 32(Suppl 3):3-13
-
(2002)
Eur J Clin Investig
, vol.32
, Issue.SUPPL. 3
, pp. 3-13
-
-
Rhodes, C.J.1
White, M.F.2
-
3
-
-
0141506880
-
Epidemic obesity and the metabolic syndrome
-
Haffner S, Taegtmeyer H (2003) Epidemic obesity and the metabolic syndrome. Circulation 108:1541-1545
-
(2003)
Circulation
, vol.108
, pp. 1541-1545
-
-
Haffner, S.1
Taegtmeyer, H.2
-
4
-
-
0141730248
-
The metabolic syndrome: More than the sum of its parts?
-
Reilly MP, Rader DJ (2003) The metabolic syndrome: more than the sum of its parts? Circulation 108:1546-1551
-
(2003)
Circulation
, vol.108
, pp. 1546-1551
-
-
Reilly, M.P.1
Rader, D.J.2
-
5
-
-
0037021505
-
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
-
Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, Salonen JT (2002) The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 288:2709-2716
-
(2002)
JAMA
, vol.288
, pp. 2709-2716
-
-
Lakka, H.M.1
Laaksonen, D.E.2
Lakka, T.A.3
Niskanen, L.K.4
Kumpusalo, E.5
Tuomilehto, J.6
Salonen, J.T.7
-
6
-
-
0034002064
-
Cardiovascular risk factors clustering with endogenous hyperinsulinaemia predict death from coronary heart disease in patients with Type II diabetes
-
Lehto S, Ronnemaa T, Pyorala K, Laakso M (2000) Cardiovascular risk factors clustering with endogenous hyperinsulinaemia predict death from coronary heart disease in patients with Type II diabetes. Diabetologia 43:148-155
-
(2000)
Diabetologia
, vol.43
, pp. 148-155
-
-
Lehto, S.1
Ronnemaa, T.2
Pyorala, K.3
Laakso, M.4
-
7
-
-
0042767042
-
Minimal model-based insulin sensitivity has greater heritability and a different genetic basis than homeostasis model assessment or fasting insulin
-
Bergman RN, Zaccaro DJ, Watanabe RM, Haffner SM, Saad MF, Norris JM, Wagenknecht LE, Hokanson JE, Rotter JI, Rich SS (2003) Minimal model-based insulin sensitivity has greater heritability and a different genetic basis than homeostasis model assessment or fasting insulin. Diabetes 52:2168-2174
-
(2003)
Diabetes
, vol.52
, pp. 2168-2174
-
-
Bergman, R.N.1
Zaccaro, D.J.2
Watanabe, R.M.3
Haffner, S.M.4
Saad, M.F.5
Norris, J.M.6
Wagenknecht, L.E.7
Hokanson, J.E.8
Rotter, J.I.9
Rich, S.S.10
-
8
-
-
33751097948
-
Nutrition recommendations and intervention for diabetes - 2006 (Position Statement)
-
American Diabetes Association
-
American Diabetes Association (2006) Nutrition recommendations and intervention for diabetes - 2006 (Position Statement). Diabetes Care 29:2140-2157
-
(2006)
Diabetes Care
, vol.29
, pp. 2140-2157
-
-
-
9
-
-
27444443876
-
Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
-
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F (2005) Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112:2735-2752
-
(2005)
Circulation
, vol.112
, pp. 2735-2752
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
Donato, K.A.4
Eckel, R.H.5
Franklin, B.A.6
Gordon, D.J.7
Krauss, R.M.8
Savage, P.J.9
Smith Jr, S.C.10
Spertus, J.A.11
Costa, F.12
-
10
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn BB, Flier JS (2000) Obesity and insulin resistance. J Clin Invest 106:473-481
-
(2000)
J Clin Invest
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
11
-
-
4243098381
-
Dietary fat, insulin sensitivity and the metabolic syndrome
-
Riccardi G, Giacco R, Rivellese AA (2004) Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr 23:447-456
-
(2004)
Clin Nutr
, vol.23
, pp. 447-456
-
-
Riccardi, G.1
Giacco, R.2
Rivellese, A.A.3
-
12
-
-
0035985217
-
Serum fatty acid composition predicts development of impaired fasting glycaemia and diabetes in middle-aged men
-
Laaksonen DE, Lakka TA, Lakka HM, Nyyssonen K, Rissanen T, Niskanen LK, Salonen JT (2002) Serum fatty acid composition predicts development of impaired fasting glycaemia and diabetes in middle-aged men. Diabet Med 19:456-464
-
(2002)
Diabet Med
, vol.19
, pp. 456-464
-
-
Laaksonen, D.E.1
Lakka, T.A.2
Lakka, H.M.3
Nyyssonen, K.4
Rissanen, T.5
Niskanen, L.K.6
Salonen, J.T.7
-
13
-
-
0035204021
-
A Mediterranean and a high-carbohydrate diet improve glucose metabolism in healthy young persons
-
Perez-Jimenez F, Lopez-Miranda J, Pinillos MD, Gomez P, Paz-Rojas E, Montilla P, Marin C, Velasco MJ, Blanco-Molina A, Jimenez Pereperez JA, Ordovas JM (2001) A Mediterranean and a high-carbohydrate diet improve glucose metabolism in healthy young persons. Diabetologia 44:2038-2043
-
(2001)
Diabetologia
, vol.44
, pp. 2038-2043
-
-
Perez-Jimenez, F.1
Lopez-Miranda, J.2
Pinillos, M.D.3
Gomez, P.4
Paz-Rojas, E.5
Montilla, P.6
Marin, C.7
Velasco, M.J.8
Blanco-Molina, A.9
Jimenez Pereperez, J.A.10
Ordovas, J.M.11
-
14
-
-
0035081372
-
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study
-
Vessby B, Unsitupa M, Hermansen K, Riccardi G, Rivellese AA, Tapsell LC, Nalsen C, Berglund L, Louheranta A, Rasmussen BM, Calvert GD, Maffetone A, Pedersen E, Gustafsson IB, Storlien LH (2001) Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU Study. Diabetologia 44:312-319
-
(2001)
Diabetologia
, vol.44
, pp. 312-319
-
-
Vessby, B.1
Unsitupa, M.2
Hermansen, K.3
Riccardi, G.4
Rivellese, A.A.5
Tapsell, L.C.6
Nalsen, C.7
Berglund, L.8
Louheranta, A.9
Rasmussen, B.M.10
Calvert, G.D.11
Maffetone, A.12
Pedersen, E.13
Gustafsson, I.B.14
Storlien, L.H.15
-
15
-
-
0034905492
-
Effect of the pattern of elevated free fatty acids on insulin sensitivity and insulin secretion in healthy humans
-
Stefan N, Wahl HG, Fritsche A, Haring H, Stumvoll M (2001) Effect of the pattern of elevated free fatty acids on insulin sensitivity and insulin secretion in healthy humans. Horm Metab Res 33:432-438
-
(2001)
Horm Metab Res
, vol.33
, pp. 432-438
-
-
Stefan, N.1
Wahl, H.G.2
Fritsche, A.3
Haring, H.4
Stumvoll, M.5
-
16
-
-
28844485678
-
Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A review
-
Lombardo YB, Chicco AG (2006) Effects of dietary polyunsaturated n-3 fatty acids on dyslipidemia and insulin resistance in rodents and humans. A review. J Nutr Biochem 17:1-13
-
(2006)
J Nutr Biochem
, vol.17
, pp. 1-13
-
-
Lombardo, Y.B.1
Chicco, A.G.2
-
17
-
-
0018961854
-
Substituting polyunsaturated for saturated fat as a single change in a Swedish diet: Effects on serum lipoprotein metabolism and glucose tolerance in patients with hyperlipoproteinaemia
-
Vessby B, Gustafsson IB, Boberg J, Karlstrom B, Lithell H, Werner I (1980) Substituting polyunsaturated for saturated fat as a single change in a Swedish diet: effects on serum lipoprotein metabolism and glucose tolerance in patients with hyperlipoproteinaemia. Eur J Clin Investig 10:193-202
-
(1980)
Eur J Clin Investig
, vol.10
, pp. 193-202
-
-
Vessby, B.1
Gustafsson, I.B.2
Boberg, J.3
Karlstrom, B.4
Lithell, H.5
Werner, I.6
-
18
-
-
0026051917
-
Inverse association between fish intake and risk of glucose intolerance in normoglycemic elderly men and women
-
Feskens EJ, Bowles CH, Kromhout D (1991) Inverse association between fish intake and risk of glucose intolerance in normoglycemic elderly men and women. Diabetes Care 14:935-941
-
(1991)
Diabetes Care
, vol.14
, pp. 935-941
-
-
Feskens, E.J.1
Bowles, C.H.2
Kromhout, D.3
-
19
-
-
0029083352
-
Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study
-
Feskens EJ, Virtanen SM, Rasanen L, Tuomilehto J, Stengard J, Pekkanen J, Nissinen A, Kromhout D (1995) Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study. Diabetes Care 18:1104-1112
-
(1995)
Diabetes Care
, vol.18
, pp. 1104-1112
-
-
Feskens, E.J.1
Virtanen, S.M.2
Rasanen, L.3
Tuomilehto, J.4
Stengard, J.5
Pekkanen, J.6
Nissinen, A.7
Kromhout, D.8
-
20
-
-
0029964924
-
Long-term effects of fish oil on insulin resistance and plasma lipoproteins in NIDDM patients with hypertriglyceridemia
-
Rivellese AA, Maffettone A, Iovine C, Di Marino L, Annuzzi G, Mancini M, Riccardi G (1996) Long-term effects of fish oil on insulin resistance and plasma lipoproteins in NIDDM patients with hypertriglyceridemia. Diabetes Care 19:1207-1213
-
(1996)
Diabetes Care
, vol.19
, pp. 1207-1213
-
-
Rivellese, A.A.1
Maffettone, A.2
Iovine, C.3
Di Marino, L.4
Annuzzi, G.5
Mancini, M.6
Riccardi, G.7
-
21
-
-
0036297756
-
Desaturation and elongation of fatty acids and insulin action
-
Vessby B, Gustafsson IB, Tengblad S, Boberg M, Andersson A (2002) Desaturation and elongation of fatty acids and insulin action. Ann NY Acad Sci 967:183-195
-
(2002)
Ann NY Acad Sci
, vol.967
, pp. 183-195
-
-
Vessby, B.1
Gustafsson, I.B.2
Tengblad, S.3
Boberg, M.4
Andersson, A.5
-
22
-
-
26244436986
-
Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men
-
Warensjo E, Riserus U, Vessby B (2005) Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men. Diabetologia 48:1999-2005
-
(2005)
Diabetologia
, vol.48
, pp. 1999-2005
-
-
Warensjo, E.1
Riserus, U.2
Vessby, B.3
-
23
-
-
0037143752
-
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity
-
Ntambi JM, Miyazaki M, Stoehr JP, Lan H, Kendziorski CM, Yandell BS, Song Y, Cohen P, Friedman JM, Attie AD (2002) Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci USA 99:11482-11486
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11482-11486
-
-
Ntambi, J.M.1
Miyazaki, M.2
Stoehr, J.P.3
Lan, H.4
Kendziorski, C.M.5
Yandell, B.S.6
Song, Y.7
Cohen, P.8
Friedman, J.M.9
Attie, A.D.10
-
24
-
-
33644821916
-
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
-
Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, Muoio DM (2005) Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab 2:251-261
-
(2005)
Cell Metab
, vol.2
, pp. 251-261
-
-
Hulver, M.W.1
Berggren, J.R.2
Carper, M.J.3
Miyazaki, M.4
Ntambi, J.M.5
Hoffman, E.P.6
Thyfault, J.P.7
Stevens, R.8
Dohm, G.L.9
Houmard, J.A.10
Muoio, D.M.11
-
25
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger G, Liang G, Aparicio A, Jones PA (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-463
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
26
-
-
0347123629
-
Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases
-
Waterland RA, Jirtle RL (2004) Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition 20:63-68
-
(2004)
Nutrition
, vol.20
, pp. 63-68
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
27
-
-
84910110212
-
The insulin resistance syndrome: Impact on lipoprotein metabolism and atherothrombosis
-
Ginsberg HN, Huang LS (2000) The insulin resistance syndrome: impact on lipoprotein metabolism and atherothrombosis. J Cardiovasc Risk 7:325-331
-
(2000)
J Cardiovasc Risk
, vol.7
, pp. 325-331
-
-
Ginsberg, H.N.1
Huang, L.S.2
-
28
-
-
1842452946
-
Gene variants, insulin resistance, and dyslipidaemia
-
Laakso M (2004) Gene variants, insulin resistance, and dyslipidaemia. Curr Opin Lipidol 15:115-120
-
(2004)
Curr Opin Lipidol
, vol.15
, pp. 115-120
-
-
Laakso, M.1
-
29
-
-
0347990586
-
Lipoprotein lipase is a gene for insulin resistance in Mexican Americans
-
Goodarzi MO, Guo X, Taylor KD, Quinones MJ, Saad MF, Yang H, Hsueh WA, Rotter JI (2004) Lipoprotein lipase is a gene for insulin resistance in Mexican Americans. Diabetes 53:214-220
-
(2004)
Diabetes
, vol.53
, pp. 214-220
-
-
Goodarzi, M.O.1
Guo, X.2
Taylor, K.D.3
Quinones, M.J.4
Saad, M.F.5
Yang, H.6
Hsueh, W.A.7
Rotter, J.I.8
-
30
-
-
17844385850
-
Impact of apolipoprotein A5 polymorphisms on insulin sensitivity and beta-cell function
-
Chiu KC, Chiu YF, Boyadjian AA, Fernando S, Kwan C, Chuang LM (2005) Impact of apolipoprotein A5 polymorphisms on insulin sensitivity and beta-cell function. Pancreas 30:328-332
-
(2005)
Pancreas
, vol.30
, pp. 328-332
-
-
Chiu, K.C.1
Chiu, Y.F.2
Boyadjian, A.A.3
Fernando, S.4
Kwan, C.5
Chuang, L.M.6
-
31
-
-
25644452059
-
C-514T polymorphism in hepatic lipase gene promoter is associated with elevated triglyceride levels and decreasing insulin sensitivity in nondiabetic Japanese subjects
-
Yabu Y, Noma K, Nakatani K, Nishioka J, Suematsu M, Katsuki A, Hori Y, Yano Y, Sumida Y, Wada H, Nobori T (2005) C-514T polymorphism in hepatic lipase gene promoter is associated with elevated triglyceride levels and decreasing insulin sensitivity in nondiabetic Japanese subjects. Int J Mol Med 16:421-425
-
(2005)
Int J Mol Med
, vol.16
, pp. 421-425
-
-
Yabu, Y.1
Noma, K.2
Nakatani, K.3
Nishioka, J.4
Suematsu, M.5
Katsuki, A.6
Hori, Y.7
Yano, Y.8
Sumida, Y.9
Wada, H.10
Nobori, T.11
-
32
-
-
2442600044
-
The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: The Finnish Diabetes Prevention Study
-
Todorova B, Kubaszek A, Pihlajamaki J, Lindstrom J, Eriksson J, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M (2004) The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study. J Clin Endocrinol Metab 89:2019-2023
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2019-2023
-
-
Todorova, B.1
Kubaszek, A.2
Pihlajamaki, J.3
Lindstrom, J.4
Eriksson, J.5
Valle, T.T.6
Hamalainen, H.7
Ilanne-Parikka, P.8
Keinanen-Kiukaanniemi, S.9
Tuomilehto, J.10
Uusitupa, M.11
Laakso, M.12
-
33
-
-
23044471410
-
Liver fat and insulin resistance are independently associated with the ?514C>T polymorphism of the hepatic lipase gene
-
Stefan N, Schafer S, Machicao F, Machann J, Schick F, Claussen CD, Stumvoll M, Haring HU, Fritsche A (2005) Liver fat and insulin resistance are independently associated with the ?514C>T polymorphism of the hepatic lipase gene. J Clin Endocrinol Metab 90:4238-4243
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 4238-4243
-
-
Stefan, N.1
Schafer, S.2
Machicao, F.3
Machann, J.4
Schick, F.5
Claussen, C.D.6
Stumvoll, M.7
Haring, H.U.8
Fritsche, A.9
-
34
-
-
4644279032
-
Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity
-
Gylling H, Hallikainen M, Pihlajamaki J, Agren J, Laakso M, Rajaratnam RA, Rauramaa R, Miettinen TA (2004) Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity. J Lipid Res 45:1660-1665
-
(2004)
J Lipid Res
, vol.45
, pp. 1660-1665
-
-
Gylling, H.1
Hallikainen, M.2
Pihlajamaki, J.3
Agren, J.4
Laakso, M.5
Rajaratnam, R.A.6
Rauramaa, R.7
Miettinen, T.A.8
-
35
-
-
10744222217
-
Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes
-
Laudes M, Barroso I, Luan J, Soos MA, Yeo G, Meirhaeghe A, Logie L, Vidal-Puig A, Schafer AJ, Wareham NJ, O'Rahilly S (2004) Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes. Diabetes 53:842-846
-
(2004)
Diabetes
, vol.53
, pp. 842-846
-
-
Laudes, M.1
Barroso, I.2
Luan, J.3
Soos, M.A.4
Yeo, G.5
Meirhaeghe, A.6
Logie, L.7
Vidal-Puig, A.8
Schafer, A.J.9
Wareham, N.J.10
O'Rahilly, S.11
-
36
-
-
0842312960
-
Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome
-
Gertow K, Bellanda M, Eriksson P, Boquist S, Hamsten A, Sunnerhagen M, Fisher RM (2004) Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome. J Clin Endocrinol Metab 89:392-399
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 392-399
-
-
Gertow, K.1
Bellanda, M.2
Eriksson, P.3
Boquist, S.4
Hamsten, A.5
Sunnerhagen, M.6
Fisher, R.M.7
-
37
-
-
19944433545
-
Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism
-
Liew CF, Groves CJ, Wiltshire S, Zeggini E, Frayling TM, Owen KR, Walker M, Hitman GA, Levy JC, O'Rahilly S, Hattersley AT, Johnston DG, McCarthy MI (2004) Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism. Diabetologia 47:2168-2175
-
(2004)
Diabetologia
, vol.47
, pp. 2168-2175
-
-
Liew, C.F.1
Groves, C.J.2
Wiltshire, S.3
Zeggini, E.4
Frayling, T.M.5
Owen, K.R.6
Walker, M.7
Hitman, G.A.8
Levy, J.C.9
O'Rahilly, S.10
Hattersley, A.T.11
Johnston, D.G.12
McCarthy, M.I.13
-
38
-
-
33745454996
-
A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels
-
Rubin D, Helwig U, Pfeuffer M, Schreiber S, Boeing H, Fisher E, Pfeiffer A, Freitag-Wolf S, Foelsch UR, Doering F, Schrezenmeir J (2006) A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels. J Hum Genet 51:567-574
-
(2006)
J Hum Genet
, vol.51
, pp. 567-574
-
-
Rubin, D.1
Helwig, U.2
Pfeuffer, M.3
Schreiber, S.4
Boeing, H.5
Fisher, E.6
Pfeiffer, A.7
Freitag-Wolf, S.8
Foelsch, U.R.9
Doering, F.10
Schrezenmeir, J.11
-
39
-
-
25144487562
-
Association of Kir6.2 and INS VNTR variants with glucose homeostasis in young obese
-
Le Fur S, Fradin D, Boileau P, Bougneres P (2005) Association of Kir6.2 and INS VNTR variants with glucose homeostasis in young obese. Physiol Genomics 22:398-401
-
(2005)
Physiol Genomics
, vol.22
, pp. 398-401
-
-
Le Fur, S.1
Fradin, D.2
Boileau, P.3
Bougneres, P.4
-
40
-
-
25844509429
-
Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians
-
Muller YL, Infante AM, Hanson RL, Love-Gregory L, Knowler W, Bogardus C, Baier LJ (2005) Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians. Diabetes 54:3035-3039
-
(2005)
Diabetes
, vol.54
, pp. 3035-3039
-
-
Muller, Y.L.1
Infante, A.M.2
Hanson, R.L.3
Love-Gregory, L.4
Knowler, W.5
Bogardus, C.6
Baier, L.J.7
-
41
-
-
32544451924
-
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323
-
Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, Sainz J, Helgason A, Stefansson H, Emilsson V, Helgadottir A, Styrkarsdottir U, Magnusson KP, Walters GB, Palsdottir E, Jonsdottir T, Gudmundsdottir T, Gylfason A, Saemundsdottir J, Wilensky RL, Reilly MP, Rader DJ, Bagger Y, Christiansen C, Gudnason V, Sigurdsson G, Thorsteinsdottir U, Gulcher JR, Kong A, Stefansson K (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38:320-323
-
-
-
-
42
-
-
0141500189
-
The search for type 2 diabetes genes
-
Gloyn AL (2003) The search for type 2 diabetes genes. Ageing Res Rev 2:111-127
-
(2003)
Ageing Res Rev
, vol.2
, pp. 111-127
-
-
Gloyn, A.L.1
-
43
-
-
4243062602
-
Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action
-
Barroso I, Luan J, Middelberg RP, Harding AH, Franks PW, Jakes RW, Clayton D, Schafer AJ, O'Rahilly S, Wareham NJ (2003) Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action. PLoS Biol 1:E20
-
(2003)
PLoS Biol
, vol.1
-
-
Barroso, I.1
Luan, J.2
Middelberg, R.P.3
Harding, A.H.4
Franks, P.W.5
Jakes, R.W.6
Clayton, D.7
Schafer, A.J.8
O'Rahilly, S.9
Wareham, N.J.10
-
44
-
-
24144466446
-
The functional Q84R polymorphism of mammalian tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy
-
Prudente S, Hribal ML, Flex E, Turchi F, Morini E, De Cosmo S, Bacci S, Tassi V, Cardellini M, Lauro R, Sesti G, Dallapiccola B, Trischitta V (2005) The functional Q84R polymorphism of mammalian tribbles homolog TRB3 is associated with insulin resistance and related cardiovascular risk in Caucasians from Italy. Diabetes 54:2807-2811
-
(2005)
Diabetes
, vol.54
, pp. 2807-2811
-
-
Prudente, S.1
Hribal, M.L.2
Flex, E.3
Turchi, F.4
Morini, E.5
De Cosmo, S.6
Bacci, S.7
Tassi, V.8
Cardellini, M.9
Lauro, R.10
Sesti, G.11
Dallapiccola, B.12
Trischitta, V.13
-
45
-
-
7044272587
-
Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
-
Palmer ND, Bento JL, Mychaleckyj JC, Langefeld CD, Campbell JK, Norris JM, Haffner SM, Bergman RN, Bowden DW (2004) Association of protein tyrosine phosphatase 1B gene polymorphisms with measures of glucose homeostasis in Hispanic Americans: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study. Diabetes 53:3013-3019
-
(2004)
Diabetes
, vol.53
, pp. 3013-3019
-
-
Palmer, N.D.1
Bento, J.L.2
Mychaleckyj, J.C.3
Langefeld, C.D.4
Campbell, J.K.5
Norris, J.M.6
Haffner, S.M.7
Bergman, R.N.8
Bowden, D.W.9
-
46
-
-
7044260741
-
Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes
-
Bento JL, Palmer ND, Mychaleckyj JC, Lange LA, Langefeld CD, Rich SS, Freedman BI, Bowden DW (2004) Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. Diabetes 53:3007-3012
-
(2004)
Diabetes
, vol.53
, pp. 3007-3012
-
-
Bento, J.L.1
Palmer, N.D.2
Mychaleckyj, J.C.3
Lange, L.A.4
Langefeld, C.D.5
Rich, S.S.6
Freedman, B.I.7
Bowden, D.W.8
-
47
-
-
24344444907
-
Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism
-
Ukkola O, Rankinen T, Lakka T, Leon AS, Skinner JS, Wilmore JH, Rao DC, Kesaniemi YA, Bouchard C (2005) Protein tyrosine phosphatase 1B variant associated with fat distribution and insulin metabolism. Obes Res 13:829-834
-
(2005)
Obes Res
, vol.13
, pp. 829-834
-
-
Ukkola, O.1
Rankinen, T.2
Lakka, T.3
Leon, A.S.4
Skinner, J.S.5
Wilmore, J.H.6
Rao, D.C.7
Kesaniemi, Y.A.8
Bouchard, C.9
-
48
-
-
33644686604
-
Protein tyrosine phosphatase-1B gene PTPN1: Selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population
-
Spencer-Jones NJ, Wang X, Snieder H, Spector TD, Carter ND, O'Dell SD (2005) Protein tyrosine phosphatase-1B gene PTPN1: selection of tagging single nucleotide polymorphisms and association with body fat, insulin sensitivity, and the metabolic syndrome in a normal female population. Diabetes 54:3296-3304
-
(2005)
Diabetes
, vol.54
, pp. 3296-3304
-
-
Spencer-Jones, N.J.1
Wang, X.2
Snieder, H.3
Spector, T.D.4
Carter, N.D.5
O'Dell, S.D.6
-
49
-
-
0031057526
-
Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation
-
Bjornholm M, Kawano Y, Lehtihet M, Zierath JR (1997) Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation. Diabetes 46:524-527
-
(1997)
Diabetes
, vol.46
, pp. 524-527
-
-
Bjornholm, M.1
Kawano, Y.2
Lehtihet, M.3
Zierath, J.R.4
-
50
-
-
0343314906
-
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients
-
Krook A, Bjornholm M, Galuska D, Jiang XJ, Fahlman R, Myers MG Jr, Wallberg-Henriksson H, Zierath JR (2000) Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. Diabetes 49:284-292
-
(2000)
Diabetes
, vol.49
, pp. 284-292
-
-
Krook, A.1
Bjornholm, M.2
Galuska, D.3
Jiang, X.J.4
Fahlman, R.5
Myers Jr, M.G.6
Wallberg-Henriksson, H.7
Zierath, J.R.8
-
51
-
-
33745289664
-
A polymorphism in the AMPKalpha2 subunit gene is associated with insulin resistance and type 2 diabetes in the Japanese population
-
Horikoshi M, Hara K, Ohashi J, Miyake K, Tokunaga K, Ito C, Kasuga M, Nagai R, Kadowaki T (2006) A polymorphism in the AMPKalpha2 subunit gene is associated with insulin resistance and type 2 diabetes in the Japanese population. Diabetes 55:919-923
-
(2006)
Diabetes
, vol.55
, pp. 919-923
-
-
Horikoshi, M.1
Hara, K.2
Ohashi, J.3
Miyake, K.4
Tokunaga, K.5
Ito, C.6
Kasuga, M.7
Nagai, R.8
Kadowaki, T.9
-
52
-
-
0031852665
-
Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects
-
Krook A, Roth RA, Jiang XJ, Zierath JR, Wallberg-Henriksson H (1998) Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. Diabetes 47:1281-1286
-
(1998)
Diabetes
, vol.47
, pp. 1281-1286
-
-
Krook, A.1
Roth, R.A.2
Jiang, X.J.3
Zierath, J.R.4
Wallberg-Henriksson, H.5
-
53
-
-
0032765342
-
Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus
-
Rondinone CM, Carvalho E, Wesslau C, Smith UP (1999) Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus. Diabetologia 42:819-825
-
(1999)
Diabetologia
, vol.42
, pp. 819-825
-
-
Rondinone, C.M.1
Carvalho, E.2
Wesslau, C.3
Smith, U.P.4
-
54
-
-
2342578802
-
Association of Ob-R gene polymorphism and insulin resistance in Japanese men
-
Takahashi-Yasuno A, Masuzaki H, Miyawaki T, Matsuoka N, Ogawa Y, Hayashi T, Hosoda K, Yoshimasa Y, Inoue G, Nakao K (2004) Association of Ob-R gene polymorphism and insulin resistance in Japanese men. Metabolism 53:650-654
-
(2004)
Metabolism
, vol.53
, pp. 650-654
-
-
Takahashi-Yasuno, A.1
Masuzaki, H.2
Miyawaki, T.3
Matsuoka, N.4
Ogawa, Y.5
Hayashi, T.6
Hosoda, K.7
Yoshimasa, Y.8
Inoue, G.9
Nakao, K.10
-
55
-
-
2942718557
-
Association of leptin receptor polymorphism with insulin resistance
-
Chiu KC, Chu A, Chuang LM, Saad MF (2004) Association of leptin receptor polymorphism with insulin resistance. Eur J Endocrinol 150:725-729
-
(2004)
Eur J Endocrinol
, vol.150
, pp. 725-729
-
-
Chiu, K.C.1
Chu, A.2
Chuang, L.M.3
Saad, M.F.4
-
56
-
-
3042579670
-
Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population
-
Ogawa T, Hirose H, Yamamoto Y, Nishikai K, Miyashita K, Nakamura H, Saito I, Saruta T (2004) Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population. Metabolism 53:879-885
-
(2004)
Metabolism
, vol.53
, pp. 879-885
-
-
Ogawa, T.1
Hirose, H.2
Yamamoto, Y.3
Nishikai, K.4
Miyashita, K.5
Nakamura, H.6
Saito, I.7
Saruta, T.8
-
57
-
-
22844435290
-
Beta2-adrenoceptor polymorphisms relate to insulin resistance and sympathetic overactivity as early markers of metabolic disease in nonobese, normotensive individuals
-
Masuo K, Katsuya T, Fu Y, Rakugi H, Ogihara T, Tuck ML (2005) Beta2-adrenoceptor polymorphisms relate to insulin resistance and sympathetic overactivity as early markers of metabolic disease in nonobese, normotensive individuals. Am J Hypertens 18:1009-1014
-
(2005)
Am J Hypertens
, vol.18
, pp. 1009-1014
-
-
Masuo, K.1
Katsuya, T.2
Fu, Y.3
Rakugi, H.4
Ogihara, T.5
Tuck, M.L.6
-
58
-
-
33644811949
-
Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with insulin resistance
-
Zhan S, Ho SC (2005) Meta-analysis of the association of the Trp64Arg polymorphism in the beta3 adrenergic receptor with insulin resistance. Obes Res 13:1709-1719
-
(2005)
Obes Res
, vol.13
, pp. 1709-1719
-
-
Zhan, S.1
Ho, S.C.2
-
59
-
-
12144291012
-
Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: The epidemiologic data on the insulin resistance syndrome prospective study
-
Fumeron F, Aubert R, Siddiq A, Betoulle D, Pean F, Hadjadj S, Tichet J, Wilpart E, Chesnier MC, Balkau B, Froguel P, Marre M (2004) Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study. Diabetes 53:1150-1157
-
(2004)
Diabetes
, vol.53
, pp. 1150-1157
-
-
Fumeron, F.1
Aubert, R.2
Siddiq, A.3
Betoulle, D.4
Pean, F.5
Hadjadj, S.6
Tichet, J.7
Wilpart, E.8
Chesnier, M.C.9
Balkau, B.10
Froguel, P.11
Marre, M.12
-
60
-
-
0347990597
-
Genetic variation at the adiponectin locus and risk of type 2 diabetes in women
-
Hu FB, Doria A, Li T, Meigs JB, Liu S, Memisoglu A, Hunter D, Manson JE (2004) Genetic variation at the adiponectin locus and risk of type 2 diabetes in women. Diabetes 53:209-213
-
(2004)
Diabetes
, vol.53
, pp. 209-213
-
-
Hu, F.B.1
Doria, A.2
Li, T.3
Meigs, J.B.4
Liu, S.5
Memisoglu, A.6
Hunter, D.7
Manson, J.E.8
-
61
-
-
28444446323
-
The SNP276G>T polymorphism in the adiponectin (ACDC) gene is more strongly associated with insulin resistance and cardiovascular disease risk than SNP45T>G in nonobese/nondiabetic Korean men independent of abdominal adiposity and circulating plasma adiponectin
-
Jang Y, Lee JH, Kim OY, Koh SJ, Chae JS, Woo JH, Cho H, Lee JE, Ordovas JM (2006) The SNP276G>T polymorphism in the adiponectin (ACDC) gene is more strongly associated with insulin resistance and cardiovascular disease risk than SNP45T>G in nonobese/nondiabetic Korean men independent of abdominal adiposity and circulating plasma adiponectin. Metabolism 55:59-66
-
(2006)
Metabolism
, vol.55
, pp. 59-66
-
-
Jang, Y.1
Lee, J.H.2
Kim, O.Y.3
Koh, S.J.4
Chae, J.S.5
Woo, J.H.6
Cho, H.7
Lee, J.E.8
Ordovas, J.M.9
-
62
-
-
27744492082
-
Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat
-
Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, Spieth C, Weigert C, Fritsche A, Stumvoll M, Haring HU (2005) Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia 48:2282-2291
-
(2005)
Diabetologia
, vol.48
, pp. 2282-2291
-
-
Stefan, N.1
Machicao, F.2
Staiger, H.3
Machann, J.4
Schick, F.5
Tschritter, O.6
Spieth, C.7
Weigert, C.8
Fritsche, A.9
Stumvoll, M.10
Haring, H.U.11
-
63
-
-
33644784937
-
Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population
-
Vaxillaire M, Dechaume A, Vasseur-Delannoy V, Lahmidi S, Vatin V, Lepretre F, Boutin P, Hercberg S, Charpentier G, Dina C, Froguel P (2006) Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population. Diabetes 55:856-861
-
(2006)
Diabetes
, vol.55
, pp. 856-861
-
-
Vaxillaire, M.1
Dechaume, A.2
Vasseur-Delannoy, V.3
Lahmidi, S.4
Vatin, V.5
Lepretre, F.6
Boutin, P.7
Hercberg, S.8
Charpentier, G.9
Dina, C.10
Froguel, P.11
-
64
-
-
33646339674
-
The ?8503 G/A polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity
-
Kantartzis K, Fritsche A, Machicao F, Haring HU, Stefan N (2006) The ?8503 G/A polymorphism of the adiponectin receptor 1 gene is associated with insulin sensitivity dependent on adiposity. Diabetes Care 29:464
-
(2006)
Diabetes Care
, vol.29
, pp. 464
-
-
Kantartzis, K.1
Fritsche, A.2
Machicao, F.3
Haring, H.U.4
Stefan, N.5
-
65
-
-
15744403957
-
Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Quebec family study
-
Bouchard L, Weisnagel SJ, Engert JC, Hudson TJ, Bouchard C, Vohl MC, Perusse L (2004) Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Quebec family study. J Endocrinol Investig 27:1003-1009
-
(2004)
J Endocrinol Investig
, vol.27
, pp. 1003-1009
-
-
Bouchard, L.1
Weisnagel, S.J.2
Engert, J.C.3
Hudson, T.J.4
Bouchard, C.5
Vohl, M.C.6
Perusse, L.7
-
66
-
-
4544351272
-
The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3
-
Osawa H, Yamada K, Onuma H, Murakami A, Ochi M, Kawata H, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino H (2004) The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3. Am J Hum Genet 75:678-686
-
(2004)
Am J Hum Genet
, vol.75
, pp. 678-686
-
-
Osawa, H.1
Yamada, K.2
Onuma, H.3
Murakami, A.4
Ochi, M.5
Kawata, H.6
Nishimiya, T.7
Niiya, T.8
Shimizu, I.9
Nishida, W.10
Hashiramoto, M.11
Kanatsuka, A.12
Fujii, Y.13
Ohashi, J.14
Makino, H.15
-
67
-
-
3042698328
-
The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes
-
D'Adamo M, Perego L, Cardellini M, Marini MA, Frontoni S, Andreozzi F, Sciacqua A, Lauro D, Sbraccia P, Federici M, Paganelli M, Pontiroli AE, Lauro R, Perticone F, Folli F, Sesti G (2004) The -866A/A genotype in the promoter of the human uncoupling protein 2 gene is associated with insulin resistance and increased risk of type 2 diabetes. Diabetes 53:1905-1910
-
(2004)
Diabetes
, vol.53
, pp. 1905-1910
-
-
D'Adamo, M.1
Perego, L.2
Cardellini, M.3
Marini, M.A.4
Frontoni, S.5
Andreozzi, F.6
Sciacqua, A.7
Lauro, D.8
Sbraccia, P.9
Federici, M.10
Paganelli, M.11
Pontiroli, A.E.12
Lauro, R.13
Perticone, F.14
Folli, F.15
Sesti, G.16
-
68
-
-
23044461195
-
The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: The CARDIA Study
-
Yu X, Jacobs DR Jr, Schreiner PJ, Gross MD, Steffes MW, Fornage M (2005) The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA Study. Clin Chem 51:1451-1456
-
(2005)
Clin Chem
, vol.51
, pp. 1451-1456
-
-
Yu, X.1
Jacobs Jr, D.R.2
Schreiner, P.J.3
Gross, M.D.4
Steffes, M.W.5
Fornage, M.6
-
69
-
-
33746386861
-
Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, low-carbohydrate diet
-
Corella D, Qi L, Tai ES, Deurenberg-Yap M, Tan CE, Chew SK, Ordovas JM (2006) Perilipin gene variation determines higher susceptibility to insulin resistance in Asian women when consuming a high-saturated fat, low-carbohydrate diet. Diabetes Care 29:1313-1319
-
(2006)
Diabetes Care
, vol.29
, pp. 1313-1319
-
-
Corella, D.1
Qi, L.2
Tai, E.S.3
Deurenberg-Yap, M.4
Tan, C.E.5
Chew, S.K.6
Ordovas, J.M.7
-
70
-
-
0141839103
-
Novel concepts in insulin regulation of hepatic gluconeogenesis
-
Barthel A, Schmoll D (2003) Novel concepts in insulin regulation of hepatic gluconeogenesis. Am J Physiol Endocrinol Metab 285:E685-E692
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Barthel, A.1
Schmoll, D.2
-
71
-
-
2542528670
-
A family with severe insulin resistance and diabetes due to a mutation in AKT2
-
George S, Rochford JJ, Wolfrum C, Gray SL, Schinner S, Wilson JC, Soos MA, Murgatroyd PR, Williams RM, Acerini CL, Dunger DB, Barford D, Umpleby AM, Wareham NJ, Davies HA, Schafer AJ, Stoffel M, O'Rahilly S, Barroso I (2004) A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science 304:1325-1328
-
(2004)
Science
, vol.304
, pp. 1325-1328
-
-
George, S.1
Rochford, J.J.2
Wolfrum, C.3
Gray, S.L.4
Schinner, S.5
Wilson, J.C.6
Soos, M.A.7
Murgatroyd, P.R.8
Williams, R.M.9
Acerini, C.L.10
Dunger, D.B.11
Barford, D.12
Umpleby, A.M.13
Wareham, N.J.14
Davies, H.A.15
Schafer, A.J.16
Stoffel, M.17
O'Rahilly, S.18
Barroso, I.19
-
72
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
Puigserver P, Rhee J, Donovan J, Walkey CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D, Spiegelman BM (2003) Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423:550-555
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
73
-
-
0346055126
-
Leukocyte ABCA1 gene expression is associated with fasting glucose concentration in normoglycemic men
-
Albrecht C, Simon-Vermot I, Elliott JI, Higgins CF, Johnston DG, Valabhji J (2004) Leukocyte ABCA1 gene expression is associated with fasting glucose concentration in normoglycemic men. Metabolism 53:17-21
-
(2004)
Metabolism
, vol.53
, pp. 17-21
-
-
Albrecht, C.1
Simon-Vermot, I.2
Elliott, J.I.3
Higgins, C.F.4
Johnston, D.G.5
Valabhji, J.6
-
74
-
-
12144289924
-
The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes
-
Hamaguchi K, Terao H, Kusuda Y, Yamashita T, Hazoury Bahles JA, Cruz LM, Brugal VL, Jongchong WB, Yoshimatsu H, Sakata T (2004) The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes. J Clin Endocrinol Metab 89:1359-1364
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1359-1364
-
-
Hamaguchi, K.1
Terao, H.2
Kusuda, Y.3
Yamashita, T.4
Hazoury Bahles, J.A.5
Cruz, L.M.6
Brugal, V.L.7
Jongchong, W.B.8
Yoshimatsu, H.9
Sakata, T.10
-
75
-
-
1842584223
-
-
Morrison JA, Gruppo R, Glueck CJ, Stroop D, Fontaine RN, Wang P, Smith KL (2004) Population-specific alleles: the polymorphism (K121Q) of the human glycoprotein PC-1 gene is strongly associated with race but not with insulin resistance in black and white children. Metabolism 53:465-468
-
Morrison JA, Gruppo R, Glueck CJ, Stroop D, Fontaine RN, Wang P, Smith KL (2004) Population-specific alleles: the polymorphism (K121Q) of the human glycoprotein PC-1 gene is strongly associated with race but not with insulin resistance in black and white children. Metabolism 53:465-468
-
-
-
-
76
-
-
0035217903
-
The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance
-
Frittitta L, Baratta R, Spampinato D, Di Paola R, Pizzuti A, Vigneri R, Trischitta V (2001) The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance. J Clin Endocrinol Metab 86:5888-5891
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5888-5891
-
-
Frittitta, L.1
Baratta, R.2
Spampinato, D.3
Di Paola, R.4
Pizzuti, A.5
Vigneri, R.6
Trischitta, V.7
-
77
-
-
0041808862
-
The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia
-
Kubaszek A, Pihlajamaki J, Karhapaa P, Vauhkonen I, Laakso M (2003) The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia. Diabetes Care 26:464-467
-
(2003)
Diabetes Care
, vol.26
, pp. 464-467
-
-
Kubaszek, A.1
Pihlajamaki, J.2
Karhapaa, P.3
Vauhkonen, I.4
Laakso, M.5
-
78
-
-
0345923632
-
K121Q PC-1 gene polymorphism is not associated with insulin resistance in a Spanish population
-
Gonzalez-Sanchez JL, Martinez-Larrad MT, Fernandez-Perez C, Kubaszek A, Laakso M, Serrano-Rios M (2003) K121Q PC-1 gene polymorphism is not associated with insulin resistance in a Spanish population. Obes Res 11:603-605
-
(2003)
Obes Res
, vol.11
, pp. 603-605
-
-
Gonzalez-Sanchez, J.L.1
Martinez-Larrad, M.T.2
Fernandez-Perez, C.3
Kubaszek, A.4
Laakso, M.5
Serrano-Rios, M.6
-
79
-
-
14844336893
-
Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation
-
McGettrick AJ, Feener EP, Kahn CR (2005) Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation. J Biol Chem 280:6441-6446
-
(2005)
J Biol Chem
, vol.280
, pp. 6441-6446
-
-
McGettrick, A.J.1
Feener, E.P.2
Kahn, C.R.3
-
80
-
-
0029893417
-
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies
-
Almind K, Inoue G, Pedersen O, Kahn CR (1996) A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies. J Clin Invest 97:2569-2575
-
(1996)
J Clin Invest
, vol.97
, pp. 2569-2575
-
-
Almind, K.1
Inoue, G.2
Pedersen, O.3
Kahn, C.R.4
-
81
-
-
0037622751
-
The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients
-
Marini MA, Frontoni S, Mineo D, Bracaglia D, Cardellini M, De Nicolais P, Baroni A, D'Alfonso R, Perna M, Lauro D, Federici M, Gambardella S, Lauro R, Sesti G (2003) The Arg972 variant in insulin receptor substrate-1 is associated with an atherogenic profile in offspring of type 2 diabetic patients. J Clin Endocrinol Metab 88:3368-3371
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 3368-3371
-
-
Marini, M.A.1
Frontoni, S.2
Mineo, D.3
Bracaglia, D.4
Cardellini, M.5
De Nicolais, P.6
Baroni, A.7
D'Alfonso, R.8
Perna, M.9
Lauro, D.10
Federici, M.11
Gambardella, S.12
Lauro, R.13
Sesti, G.14
-
82
-
-
0035084073
-
The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance
-
Baroni MG, Arca M, Sentinelli F, Buzzetti R, Capici F, Lovari S, Vitale M, Romeo S, Di Mario U (2001) The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance. Diabetologia 44:367-372
-
(2001)
Diabetologia
, vol.44
, pp. 367-372
-
-
Baroni, M.G.1
Arca, M.2
Sentinelli, F.3
Buzzetti, R.4
Capici, F.5
Lovari, S.6
Vitale, M.7
Romeo, S.8
Di Mario, U.9
-
83
-
-
0036710280
-
IRS proteins and the common path to diabetes
-
White MF (2002) IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 283:E413-E422
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
White, M.F.1
-
84
-
-
0035432254
-
New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes
-
Wang H, Rissanen J, Miettinen R, Karkkainen P, Kekalainen P, Kuusisto J, Mykkanen L, Karhapaa P, Laakso M (2001) New amino acid substitutions in the IRS-2 gene in Finnish and Chinese subjects with late-onset type 2 diabetes. Diabetes 50:1949-1951
-
(2001)
Diabetes
, vol.50
, pp. 1949-1951
-
-
Wang, H.1
Rissanen, J.2
Miettinen, R.3
Karkkainen, P.4
Kekalainen, P.5
Kuusisto, J.6
Mykkanen, L.7
Karhapaa, P.8
Laakso, M.9
-
85
-
-
9444289880
-
Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes
-
Florez JC, Sjogren M, Burtt N, Orho-Melander M, Schayer S, Sun M, Almgren P, Lindblad U, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L (2004) Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes. Diabetes 53:3313-3318
-
(2004)
Diabetes
, vol.53
, pp. 3313-3318
-
-
Florez, J.C.1
Sjogren, M.2
Burtt, N.3
Orho-Melander, M.4
Schayer, S.5
Sun, M.6
Almgren, P.7
Lindblad, U.8
Tuomi, T.9
Gaudet, D.10
Hudson, T.J.11
Daly, M.J.12
Ardlie, K.G.13
Hirschhorn, J.N.14
Altshuler, D.15
Groop, L.16
-
86
-
-
0038645828
-
The metabolic syndrome: Peroxisome proliferator-activated receptor gamma and its therapeutic modulation
-
Gurnell M, Savage DB, Chatterjee VK, O'Rahilly S (2003) The metabolic syndrome: peroxisome proliferator-activated receptor gamma and its therapeutic modulation. J Clin Endocrinol Metab 88:2412-2421
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2412-2421
-
-
Gurnell, M.1
Savage, D.B.2
Chatterjee, V.K.3
O'Rahilly, S.4
-
87
-
-
0346219295
-
Effect of thiazolidinediones on body weight in patients with diabetes mellitus
-
Fonseca V (2003) Effect of thiazolidinediones on body weight in patients with diabetes mellitus. Am J Med 115(Suppl 8A):42S-48S
-
(2003)
Am J Med
, vol.115
, Issue.SUPPL. 8A
-
-
Fonseca, V.1
-
88
-
-
0031595923
-
A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb SS, Fajas L, Nemoto M, Pihlajamaki J, Mykkanen L, Kuusisto J, Laakso M, Fujimoto W, Auwerx J (1998) A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nat Genet 20:284-287
-
(1998)
Nat Genet
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamaki, J.4
Mykkanen, L.5
Kuusisto, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.9
-
89
-
-
0033624575
-
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, Nemesh J, Lane CR, Schaffner SF, Bolk S, Brewer C, Tuomi T, Gaudet D, Hudson TJ, Daly M, Groop L, Lander ES (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26:76-80
-
(2000)
Nat Genet
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
Tuomi, T.11
Gaudet, D.12
Hudson, T.J.13
Daly, M.14
Groop, L.15
Lander, E.S.16
-
90
-
-
9644275540
-
Association of Pro12Ala polymorphism of PPARgamma gene with insulin resistance and related diseases
-
Horiki M, Ikegami H, Fujisawa T, Kawabata Y, Ono M, Nishino M, Shimamoto K, Ogihara T (2004) Association of Pro12Ala polymorphism of PPARgamma gene with insulin resistance and related diseases. Diabetes Res Clin Pract 66(Suppl 1):S63-S67
-
(2004)
Diabetes Res Clin Pract
, vol.66
, Issue.SUPPL. 1
-
-
Horiki, M.1
Ikegami, H.2
Fujisawa, T.3
Kawabata, Y.4
Ono, M.5
Nishino, M.6
Shimamoto, K.7
Ogihara, T.8
-
91
-
-
33745291825
-
The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: The data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) Study
-
Jaziri R, Lobbens S, Aubert R, Pean F, Lahmidi S, Vaxillaire M, Porchay I, Bellili N, Tichet J, Balkau B, Froguel P, Marre M, Fumeron F (2006) The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) Study. Diabetes 55:1157-1162
-
(2006)
Diabetes
, vol.55
, pp. 1157-1162
-
-
Jaziri, R.1
Lobbens, S.2
Aubert, R.3
Pean, F.4
Lahmidi, S.5
Vaxillaire, M.6
Porchay, I.7
Bellili, N.8
Tichet, J.9
Balkau, B.10
Froguel, P.11
Marre, M.12
Fumeron, F.13
-
92
-
-
23044478560
-
The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: A positron emission tomography study
-
Vanttinen M, Nuutila P, Pihlajamaki J, Hallsten K, Virtanen KA, Lautamaki R, Peltoniemi P, Kemppainen J, Takala T, Viljanen AP, Knuuti J, Laakso M (2005) The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study. J Clin Endocrinol Metab 90:4249-4254
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 4249-4254
-
-
Vanttinen, M.1
Nuutila, P.2
Pihlajamaki, J.3
Hallsten, K.4
Virtanen, K.A.5
Lautamaki, R.6
Peltoniemi, P.7
Kemppainen, J.8
Takala, T.9
Viljanen, A.P.10
Knuuti, J.11
Laakso, M.12
-
93
-
-
0036329369
-
Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study
-
Lindi VI, Uusitupa MI, Lindstrom J, Louheranta A, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Laakso M, Tuomilehto J (2002) Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study. Diabetes 51:2581-2586
-
(2002)
Diabetes
, vol.51
, pp. 2581-2586
-
-
Lindi, V.I.1
Uusitupa, M.I.2
Lindstrom, J.3
Louheranta, A.4
Eriksson, J.G.5
Valle, T.T.6
Hamalainen, H.7
Ilanne-Parikka, P.8
Keinanen-Kiukaanniemi, S.9
Laakso, M.10
Tuomilehto, J.11
-
94
-
-
0141886852
-
The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth
-
Eriksson J, Lindi V, Uusitupa M, Forsen T, Laakso M, Osmond C, Barker D (2003) The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth. Clin Genet 64:366-370
-
(2003)
Clin Genet
, vol.64
, pp. 366-370
-
-
Eriksson, J.1
Lindi, V.2
Uusitupa, M.3
Forsen, T.4
Laakso, M.5
Osmond, C.6
Barker, D.7
-
95
-
-
10044291717
-
The common PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity
-
Buzzetti R, Petrone A, Ribaudo MC, Alemanno I, Zavarella S, Mein CA, Maiani F, Tiberti C, Baroni MG, Vecci E, Arca M, Leonetti F, di Mario U (2004) The common PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity. Eur J Hum Genet 12:1050-1054
-
(2004)
Eur J Hum Genet
, vol.12
, pp. 1050-1054
-
-
Buzzetti, R.1
Petrone, A.2
Ribaudo, M.C.3
Alemanno, I.4
Zavarella, S.5
Mein, C.A.6
Maiani, F.7
Tiberti, C.8
Baroni, M.G.9
Vecci, E.10
Arca, M.11
Leonetti, F.12
di Mario, U.13
-
96
-
-
11144249859
-
PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity
-
Buzzetti R, Petrone A, Caiazzo AM, Alemanno I, Zavarella S, Capizzi M, Mein CA, Osborn JA, Vania A, di Mario U (2005) PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity. Pediatr Res 57:138-140
-
(2005)
Pediatr Res
, vol.57
, pp. 138-140
-
-
Buzzetti, R.1
Petrone, A.2
Caiazzo, A.M.3
Alemanno, I.4
Zavarella, S.5
Capizzi, M.6
Mein, C.A.7
Osborn, J.A.8
Vania, A.9
di Mario, U.10
-
97
-
-
23844478959
-
Association between Pro12Ala polymorphism of the PPAR-gamma2 gene and insulin sensitivity in Brazilian patients with type-2 diabetes mellitus
-
Tavares V, Hirata RD, Rodrigues AC, Monte O, Salles JE, Scalissi N, Speranza AC, Hirata MH (2005) Association between Pro12Ala polymorphism of the PPAR-gamma2 gene and insulin sensitivity in Brazilian patients with type-2 diabetes mellitus. Diabetes Obes Metab 7:605-611
-
(2005)
Diabetes Obes Metab
, vol.7
, pp. 605-611
-
-
Tavares, V.1
Hirata, R.D.2
Rodrigues, A.C.3
Monte, O.4
Salles, J.E.5
Scalissi, N.6
Speranza, A.C.7
Hirata, M.H.8
-
98
-
-
27344447399
-
The C161->T polymorphism in peroxisome proliferator- activated receptor gamma, but not P12A, is associated with insulin resistance in Hispanic and non-Hispanic white women: Evidence for another functional variant in peroxisome proliferator-activated receptor gamma
-
Moffett SP, Feingold E, Barmada MM, Damcott CM, Marshall JA, Hamman RF, Ferrell RE (2005) The C161->T polymorphism in peroxisome proliferator- activated receptor gamma, but not P12A, is associated with insulin resistance in Hispanic and non-Hispanic white women: evidence for another functional variant in peroxisome proliferator-activated receptor gamma. Metabolism 54:1552-1556
-
(2005)
Metabolism
, vol.54
, pp. 1552-1556
-
-
Moffett, S.P.1
Feingold, E.2
Barmada, M.M.3
Damcott, C.M.4
Marshall, J.A.5
Hamman, R.F.6
Ferrell, R.E.7
-
99
-
-
4744340732
-
Impact of genetic variation of PPARgamma in humans
-
Meirhaeghe A, Amouyel P (2004) Impact of genetic variation of PPARgamma in humans. Mol Genet Metab 83:93-102
-
(2004)
Mol Genet Metab
, vol.83
, pp. 93-102
-
-
Meirhaeghe, A.1
Amouyel, P.2
-
100
-
-
0344944629
-
Evidence for genetic epistasis in human insulin resistance: The combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms
-
Baratta R, Di Paola R, Spampinato D, Fini G, Marucci A, Coco A, Vigneri R, Frittitta L, Trischitta V (2003) Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms. J Mol Med 81:718-723
-
(2003)
J Mol Med
, vol.81
, pp. 718-723
-
-
Baratta, R.1
Di Paola, R.2
Spampinato, D.3
Fini, G.4
Marucci, A.5
Coco, A.6
Vigneri, R.7
Frittitta, L.8
Trischitta, V.9
-
101
-
-
1842610797
-
Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males
-
Damcott CM, Moffett SP, Feingold E, Barmada MM, Marshall JA, Hamman RF, Ferrell RE (2004) Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males. Metabolism 53:303-309
-
(2004)
Metabolism
, vol.53
, pp. 303-309
-
-
Damcott, C.M.1
Moffett, S.P.2
Feingold, E.3
Barmada, M.M.4
Marshall, J.A.5
Hamman, R.F.6
Ferrell, R.E.7
-
102
-
-
23944504923
-
Peroxisome proliferator-activated receptor gamma coactivator 1 alpha promoter polymorphisms are associated with early-onset type 2 diabetes mellitus in the Korean population
-
Kim JH, Shin HD, Park BL, Cho YM, Kim SY, Lee HK, Park KS (2005) Peroxisome proliferator-activated receptor gamma coactivator 1 alpha promoter polymorphisms are associated with early-onset type 2 diabetes mellitus in the Korean population. Diabetologia 48:1323-1330
-
(2005)
Diabetologia
, vol.48
, pp. 1323-1330
-
-
Kim, J.H.1
Shin, H.D.2
Park, B.L.3
Cho, Y.M.4
Kim, S.Y.5
Lee, H.K.6
Park, K.S.7
-
103
-
-
0346739933
-
Fatty acid binding protein-2 gene variants and insulin resistance: Gene and gene-environment interaction effects
-
Weiss EP, Brown MD, Shuldiner AR, Hagberg JM (2002) Fatty acid binding protein-2 gene variants and insulin resistance: gene and gene-environment interaction effects. Physiol Genomics 10:145-157
-
(2002)
Physiol Genomics
, vol.10
, pp. 145-157
-
-
Weiss, E.P.1
Brown, M.D.2
Shuldiner, A.R.3
Hagberg, J.M.4
-
104
-
-
0028940934
-
An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance
-
Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tataranni PA, Mochizuki H, Bennett PH, Bogardus C, Prochazka M (1995) An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance. J Clin Invest 95:1281-1287
-
(1995)
J Clin Invest
, vol.95
, pp. 1281-1287
-
-
Baier, L.J.1
Sacchettini, J.C.2
Knowler, W.C.3
Eads, J.4
Paolisso, G.5
Tataranni, P.A.6
Mochizuki, H.7
Bennett, P.H.8
Bogardus, C.9
Prochazka, M.10
-
105
-
-
0035403711
-
Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study
-
Galluzzi JR, Cupples LA, Meigs JB, Wilson PW, Schaefer EJ, Ordovas JM (2001) Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study. Diabetes Care 24:1161-1166
-
(2001)
Diabetes Care
, vol.24
, pp. 1161-1166
-
-
Galluzzi, J.R.1
Cupples, L.A.2
Meigs, J.B.3
Wilson, P.W.4
Schaefer, E.J.5
Ordovas, J.M.6
-
106
-
-
33644556827
-
Interleukin-6-174 G > C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients
-
Testa R, Olivieri F, Bonfigli AR, Sirolla C, Boemi M, Marchegiani F, Marra M, Cenerelli S, Antonicelli R, Dolci A, Paolisso G, Franceschi C (2006) Interleukin-6-174 G > C polymorphism affects the association between IL-6 plasma levels and insulin resistance in type 2 diabetic patients. Diabetes Res Clin Pract 71:299-305
-
(2006)
Diabetes Res Clin Pract
, vol.71
, pp. 299-305
-
-
Testa, R.1
Olivieri, F.2
Bonfigli, A.R.3
Sirolla, C.4
Boemi, M.5
Marchegiani, F.6
Marra, M.7
Cenerelli, S.8
Antonicelli, R.9
Dolci, A.10
Paolisso, G.11
Franceschi, C.12
-
107
-
-
24344509287
-
Effect of the interleukin-6 (-174) g/c promoter polymorphism on adiponectin and insulin sensitivity
-
Yang X, Jansson PA, Pellme F, Laakso M, Smith U (2005) Effect of the interleukin-6 (-174) g/c promoter polymorphism on adiponectin and insulin sensitivity. Obes Res 13:813-817
-
(2005)
Obes Res
, vol.13
, pp. 813-817
-
-
Yang, X.1
Jansson, P.A.2
Pellme, F.3
Laakso, M.4
Smith, U.5
-
108
-
-
23044505300
-
C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance
-
Cardellini M, Perego L, D'Adamo M, Marini MA, Procopio C, Hribal ML, Andreozzi F, Frontoni S, Giacomelli M, Paganelli M, Pontiroli AE, Lauro R, Folli F, Sesti G (2005) C-174G polymorphism in the promoter of the interleukin-6 gene is associated with insulin resistance. Diabetes Care 28:2007-2012
-
(2005)
Diabetes Care
, vol.28
, pp. 2007-2012
-
-
Cardellini, M.1
Perego, L.2
D'Adamo, M.3
Marini, M.A.4
Procopio, C.5
Hribal, M.L.6
Andreozzi, F.7
Frontoni, S.8
Giacomelli, M.9
Paganelli, M.10
Pontiroli, A.E.11
Lauro, R.12
Folli, F.13
Sesti, G.14
-
109
-
-
3242773724
-
The C-174G promoter polymorphism of the interleukin-6 (IL-6) gene that affects insulin sensitivity in Caucasians is not involved in the pathogenesis of Taiwanese type 2 diabetes mellitus
-
Chang YH, Huang CN, Shiau MY (2004) The C-174G promoter polymorphism of the interleukin-6 (IL-6) gene that affects insulin sensitivity in Caucasians is not involved in the pathogenesis of Taiwanese type 2 diabetes mellitus. Eur Cytokine Netw 15:117-119
-
(2004)
Eur Cytokine Netw
, vol.15
, pp. 117-119
-
-
Chang, Y.H.1
Huang, C.N.2
Shiau, M.Y.3
-
110
-
-
33744779065
-
Genetic variation in IL6 gene and type 2 diabetes: Tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis
-
Qi L, van Dam RM, Meigs JB, Manson JE, Hunter D, Hu FB (2006) Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis. Hum Mol Genet 15:1914-1920
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1914-1920
-
-
Qi, L.1
van Dam, R.M.2
Meigs, J.B.3
Manson, J.E.4
Hunter, D.5
Hu, F.B.6
-
111
-
-
33745304040
-
Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in Caucasian Italian subjects
-
Scarpelli D, Cardellini M, Andreozzi F, Laratta E, Hribal ML, Marini MA, Tassi V, Lauro R, Perticone F, Sesti G (2006) Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in Caucasian Italian subjects. Diabetes 55:1529-1533
-
(2006)
Diabetes
, vol.55
, pp. 1529-1533
-
-
Scarpelli, D.1
Cardellini, M.2
Andreozzi, F.3
Laratta, E.4
Hribal, M.L.5
Marini, M.A.6
Tassi, V.7
Lauro, R.8
Perticone, F.9
Sesti, G.10
-
112
-
-
25844473422
-
The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome
-
Sookoian S, Garcia SI, Gianotti TF, Dieuzeide G, Gonzalez CD, Pirola CJ (2005) The G-308A promoter variant of the tumor necrosis factor-alpha gene is associated with hypertension in adolescents harboring the metabolic syndrome. Am J Hypertens 18:1271-1275
-
(2005)
Am J Hypertens
, vol.18
, pp. 1271-1275
-
-
Sookoian, S.1
Garcia, S.I.2
Gianotti, T.F.3
Dieuzeide, G.4
Gonzalez, C.D.5
Pirola, C.J.6
-
113
-
-
33645023504
-
The tumour necrosis factor (TNF)-alpha-308GA promoter polymorphism is related to prenatal growth and postnatal insulin resistance
-
Casano-Sancho P, Lopez-Bermejo A, Fernandez-Real JM, Monros E, Valls C, Rodriguez-Gonzalez FX, Ricart W, Ibanez L (2006) The tumour necrosis factor (TNF)-alpha-308GA promoter polymorphism is related to prenatal growth and postnatal insulin resistance. Clin Endocrinol (Oxf) 64:129-135
-
(2006)
Clin Endocrinol (Oxf)
, vol.64
, pp. 129-135
-
-
Casano-Sancho, P.1
Lopez-Bermejo, A.2
Fernandez-Real, J.M.3
Monros, E.4
Valls, C.5
Rodriguez-Gonzalez, F.X.6
Ricart, W.7
Ibanez, L.8
-
114
-
-
33645059736
-
Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome
-
Sookoian SC, Gonzalez C, Pirola CJ (2005) Meta-analysis on the G-308A tumor necrosis factor alpha gene variant and phenotypes associated with the metabolic syndrome. Obes Res 13:2122-2131
-
(2005)
Obes Res
, vol.13
, pp. 2122-2131
-
-
Sookoian, S.C.1
Gonzalez, C.2
Pirola, C.J.3
-
116
-
-
0038175197
-
Post-genomic opportunities for understanding nutrition: The nutritionist's perspective
-
Mensink RP, Plat J (2002) Post-genomic opportunities for understanding nutrition: the nutritionist's perspective. Proc Nutr Soc 61:401-404
-
(2002)
Proc Nutr Soc
, vol.61
, pp. 401-404
-
-
Mensink, R.P.1
Plat, J.2
-
118
-
-
0036085196
-
Genomics and proteomics: Importance for the future of nutrition research
-
Daniel H (2002) Genomics and proteomics: importance for the future of nutrition research. Br J Nutr 87(Suppl 2):S305-S311
-
(2002)
Br J Nutr
, vol.87
, Issue.SUPPL. 2
-
-
Daniel, H.1
-
119
-
-
0037398060
-
Omic' approaches and lipid metabolism: Are these new technologies holding their promises?
-
Mooser V, Ordovas JM (2003) 'Omic' approaches and lipid metabolism: are these new technologies holding their promises? Curr Opin Lipidol 14:115-119
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 115-119
-
-
Mooser, V.1
Ordovas, J.M.2
-
121
-
-
0344236147
-
The influence of the apolipoprotein E gene promoter (-219G/T) polymorphism on postprandial lipoprotein metabolism in young normolipemic males
-
Moreno JA, Lopez-Miranda J, Marin C, Gomez P, Perez-Martinez P, Fuentes F, Fernandez de la Puebla RA, Paniagua JA, Ordovas JM, Perez-Jimenez F (2003) The influence of the apolipoprotein E gene promoter (-219G/T) polymorphism on postprandial lipoprotein metabolism in young normolipemic males. J Lipid Res 44:2059-2064
-
(2003)
J Lipid Res
, vol.44
, pp. 2059-2064
-
-
Moreno, J.A.1
Lopez-Miranda, J.2
Marin, C.3
Gomez, P.4
Perez-Martinez, P.5
Fuentes, F.6
Fernandez de la Puebla, R.A.7
Paniagua, J.A.8
Ordovas, J.M.9
Perez-Jimenez, F.10
-
122
-
-
15044365347
-
Apolipoprotein E gene promoter -219G->T polymorphism increases LDL-cholesterol concentrations and susceptibility to oxidation in response to a diet rich in saturated fat
-
Moreno JA, Perez-Jimenez F, Marin C, Gomez P, Perez-Martinez P, Moreno R, Bellido C, Fuentes F, Lopez-Miranda J (2004) Apolipoprotein E gene promoter -219G->T polymorphism increases LDL-cholesterol concentrations and susceptibility to oxidation in response to a diet rich in saturated fat. Am J Clin Nutr 80:1404-1409
-
(2004)
Am J Clin Nutr
, vol.80
, pp. 1404-1409
-
-
Moreno, J.A.1
Perez-Jimenez, F.2
Marin, C.3
Gomez, P.4
Perez-Martinez, P.5
Moreno, R.6
Bellido, C.7
Fuentes, F.8
Lopez-Miranda, J.9
-
123
-
-
31544433663
-
The apolipoprotein E gene promoter (-219G/T) polymorphism determines insulin sensitivity in response to dietary fat in healthy young adults
-
Moreno JA, Perez-Jimenez F, Marin C, Perez-Martinez P, Moreno R, Gomez P, Jimenez-Gomez Y, Paniagua JA, Lairon D, Lopez-Miranda J (2005) The apolipoprotein E gene promoter (-219G/T) polymorphism determines insulin sensitivity in response to dietary fat in healthy young adults. J Nutr 135:2535-2540
-
(2005)
J Nutr
, vol.135
, pp. 2535-2540
-
-
Moreno, J.A.1
Perez-Jimenez, F.2
Marin, C.3
Perez-Martinez, P.4
Moreno, R.5
Gomez, P.6
Jimenez-Gomez, Y.7
Paniagua, J.A.8
Lairon, D.9
Lopez-Miranda, J.10
-
124
-
-
4644313477
-
Intestinal FABP2 A54T polymorphism: Association with insulin resistance and obesity in women
-
Albala C, Santos JL, Cifuentes M, Villarroel AC, Lera L, Liberman C, Angel B, Perez-Bravo F (2004) Intestinal FABP2 A54T polymorphism: association with insulin resistance and obesity in women. Obes Res 12:340-345
-
(2004)
Obes Res
, vol.12
, pp. 340-345
-
-
Albala, C.1
Santos, J.L.2
Cifuentes, M.3
Villarroel, A.C.4
Lera, L.5
Liberman, C.6
Angel, B.7
Perez-Bravo, F.8
-
125
-
-
28444451923
-
Comparison of the acute response to meals enriched with cis- or trans-fatty acids on glucose and lipids in overweight individuals with differing FABP2 genotypes
-
Lefevre M, Lovejoy JC, Smith SR, Delany JP, Champagne C, Most MM, Denkins Y, de Jonge L, Rood J, Bray GA (2005) Comparison of the acute response to meals enriched with cis- or trans-fatty acids on glucose and lipids in overweight individuals with differing FABP2 genotypes. Metabolism 54:1652-1658
-
(2005)
Metabolism
, vol.54
, pp. 1652-1658
-
-
Lefevre, M.1
Lovejoy, J.C.2
Smith, S.R.3
Delany, J.P.4
Champagne, C.5
Most, M.M.6
Denkins, Y.7
de Jonge, L.8
Rood, J.9
Bray, G.A.10
-
126
-
-
33744972651
-
Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort
-
Fisher E, Li Y, Burwinkel B, Kuhr V, Hoffmann K, Mohlig M, Spranger J, Pfeiffer A, Boeing H, Schrezenmeir J, Doring F (2006) Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort. Horm Metab Res 38:341-345
-
(2006)
Horm Metab Res
, vol.38
, pp. 341-345
-
-
Fisher, E.1
Li, Y.2
Burwinkel, B.3
Kuhr, V.4
Hoffmann, K.5
Mohlig, M.6
Spranger, J.7
Pfeiffer, A.8
Boeing, H.9
Schrezenmeir, J.10
Doring, F.11
-
127
-
-
23444434523
-
The Ala54Thr polymorphism of the fatty acid-binding protein 2 gene is associated with a change in insulin sensitivity after a change in the type of dietary fat
-
Marin C, Perez-Jimenez F, Gomez P, Delgado J, Paniagua JA, Lozano A, Cortes B, Jimenez-Gomez Y, Gomez MJ, Lopez-Miranda J (2005) The Ala54Thr polymorphism of the fatty acid-binding protein 2 gene is associated with a change in insulin sensitivity after a change in the type of dietary fat. Am J Clin Nutr 82:196-200
-
(2005)
Am J Clin Nutr
, vol.82
, pp. 196-200
-
-
Marin, C.1
Perez-Jimenez, F.2
Gomez, P.3
Delgado, J.4
Paniagua, J.A.5
Lozano, A.6
Cortes, B.7
Jimenez-Gomez, Y.8
Gomez, M.J.9
Lopez-Miranda, J.10
-
128
-
-
20244382685
-
The -514 C/T polymorphism in the hepatic lipase gene promoter is associated with insulin sensitivity in a healthy young population
-
Gomez P, Perez-Jimenez F, Marin C, Moreno JA, Gomez MJ, Bellido C, Perez-Martinez P, Fuentes F, Paniagua JA, Lopez-Miranda J (2005) The -514 C/T polymorphism in the hepatic lipase gene promoter is associated with insulin sensitivity in a healthy young population. J Mol Endocrinol 34:331-338
-
(2005)
J Mol Endocrinol
, vol.34
, pp. 331-338
-
-
Gomez, P.1
Perez-Jimenez, F.2
Marin, C.3
Moreno, J.A.4
Gomez, M.J.5
Bellido, C.6
Perez-Martinez, P.7
Fuentes, F.8
Paniagua, J.A.9
Lopez-Miranda, J.10
-
129
-
-
12144287296
-
Postprandial lipemia is modified by the presence of the polymorphism present in the exon 1 variant at the SR-BI gene locus
-
Perez-Martinez P, Lopez-Miranda J, Ordovas JM, Bellido C, Marin C, Gomez P, Paniagua JA, Moreno JA, Fuentes F, Perez-Jimenez F (2004) Postprandial lipemia is modified by the presence of the polymorphism present in the exon 1 variant at the SR-BI gene locus. J Mol Endocrinol 32:237-245
-
(2004)
J Mol Endocrinol
, vol.32
, pp. 237-245
-
-
Perez-Martinez, P.1
Lopez-Miranda, J.2
Ordovas, J.M.3
Bellido, C.4
Marin, C.5
Gomez, P.6
Paniagua, J.A.7
Moreno, J.A.8
Fuentes, F.9
Perez-Jimenez, F.10
-
130
-
-
20244385801
-
A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet
-
Perez-Martinez P, Perez-Jimenez F, Bellido C, Ordovas JM, Moreno JA, Marin C, Gomez P, Delgado-Lista J, Fuentes F, Lopez-Miranda J (2005) A polymorphism exon 1 variant at the locus of the scavenger receptor class B type I (SCARB1) gene is associated with differences in insulin sensitivity in healthy people during the consumption of an olive oil-rich diet. J Clin Endocrinol Metab 90:2297-2300
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 2297-2300
-
-
Perez-Martinez, P.1
Perez-Jimenez, F.2
Bellido, C.3
Ordovas, J.M.4
Moreno, J.A.5
Marin, C.6
Gomez, P.7
Delgado-Lista, J.8
Fuentes, F.9
Lopez-Miranda, J.10
-
131
-
-
19944433566
-
Apolipoprotein C-III, n-3 polyunsaturated fatty acids, and "insulin-resistant" T-455C APOC3 gene polymorphism in heart disease patients: Example of gene-diet interaction
-
Olivieri O, Martinelli N, Sandri M, Bassi A, Guarini P, Trabetti E, Pizzolo F, Girelli D, Friso S, Pignatti PF, Corrocher R (2005) Apolipoprotein C-III, n-3 polyunsaturated fatty acids, and "insulin-resistant" T-455C APOC3 gene polymorphism in heart disease patients: example of gene-diet interaction. Clin Chem 51:360-367
-
(2005)
Clin Chem
, vol.51
, pp. 360-367
-
-
Olivieri, O.1
Martinelli, N.2
Sandri, M.3
Bassi, A.4
Guarini, P.5
Trabetti, E.6
Pizzolo, F.7
Girelli, D.8
Friso, S.9
Pignatti, P.F.10
Corrocher, R.11
-
132
-
-
3242745195
-
Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension
-
Cook S, Hugli O, Egli M, Menard B, Thalmann S, Sartori C, Perrin C, Nicod P, Thorens B, Vollenweider P, Scherrer U, Burcelin R (2004) Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension. Diabetes 53:2067-2072
-
(2004)
Diabetes
, vol.53
, pp. 2067-2072
-
-
Cook, S.1
Hugli, O.2
Egli, M.3
Menard, B.4
Thalmann, S.5
Sartori, C.6
Perrin, C.7
Nicod, P.8
Thorens, B.9
Vollenweider, P.10
Scherrer, U.11
Burcelin, R.12
-
133
-
-
14944384748
-
Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study
-
Tai ES, Corella D, Demissie S, Cupples LA, Coltell O, Schaefer EJ, Tucker KL, Ordovas JM (2005) Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study. J Nutr 135:397-403
-
(2005)
J Nutr
, vol.135
, pp. 397-403
-
-
Tai, E.S.1
Corella, D.2
Demissie, S.3
Cupples, L.A.4
Coltell, O.5
Schaefer, E.J.6
Tucker, K.L.7
Ordovas, J.M.8
-
134
-
-
14544298398
-
The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men
-
Paradis AM, Fontaine-Bisson B, Bosse Y, Robitaille J, Lemieux S, Jacques H, Lamarche B, Tchernof A, Couture P, Vohl MC (2005) The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men. Am J Clin Nutr 81:523-530
-
(2005)
Am J Clin Nutr
, vol.81
, pp. 523-530
-
-
Paradis, A.M.1
Fontaine-Bisson, B.2
Bosse, Y.3
Robitaille, J.4
Lemieux, S.5
Jacques, H.6
Lamarche, B.7
Tchernof, A.8
Couture, P.9
Vohl, M.C.10
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