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Volumn 66, Issue SUPPL., 2004, Pages

Association of Pro12Ala polymorphism of PPARγ gene with insulin resistance and related diseases

Author keywords

Genetic susceptibility; Hypertension; Insulin resistance; Peroxisome proliferator activated receptor ; Polymorphism; Type 2 diabetes

Indexed keywords

ALANINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROLINE;

EID: 9644275540     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2003.09.023     Document Type: Conference Paper
Times cited : (28)

References (16)
  • 1
    • 0036224560 scopus 로고    scopus 로고
    • Insulin resistance and upper-normal glucose levels in hypertension: A review
    • L.X. Cubeddu, and I.S. Hoffmann Insulin resistance and upper-normal glucose levels in hypertension: a review J. Hum. Hypertens. Suppl. 1 2002 52 55
    • (2002) J. Hum. Hypertens. , vol.1 , pp. 52-55
    • Cubeddu, L.X.1    Hoffmann, I.S.2
  • 2
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR γ2, a lipid-activated transcription factor
    • P. Tonntonoz, E. Hu, and B.M. Spiegelman Stimulation of adipogenesis in fibroblasts by PPAR γ2, a lipid-activated transcription factor Cell 79 1994 1147 1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tonntonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 4
    • 0029154635 scopus 로고
    • Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor γ
    • P. Tontonoz, and B.M. Spiegelman Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor γ Curr. Opin. Genet. Dev. 5 1995 571 576
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 571-576
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 5
    • 0029016829 scopus 로고
    • An anti-diabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • J.M. Lehmann, L.B. Moore, T.A. Smith-Oliver, W.O. Wilkison, T.M. Willson, and S.A. Kliewer An anti-diabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma) J. Biol. Chem. 270 1995 12953 12956
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 6
    • 0038645828 scopus 로고    scopus 로고
    • The metabolic symdrome: Peroxisome proliferator-activated receptor gamma and its therpeutic modulation
    • M. Gurnell, D.B. Savage, V.K. Chatterjee, and S. O'Rahilly The metabolic symdrome: peroxisome proliferator-activated receptor gamma and its therpeutic modulation J. Clin. Endocrinal. Metab. 88 2003 2412 2421
    • (2003) J. Clin. Endocrinal. Metab. , vol.88 , pp. 2412-2421
    • Gurnell, M.1    Savage, D.B.2    Chatterjee, V.K.3    O'Rahilly, S.4
  • 7
    • 0030877565 scopus 로고    scopus 로고
    • Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPARγ)
    • A. Werman, A. Hollenberg, G. Solanes, C. Bjorbaek, A.J. Vidal-Puig, and J.S. Flier Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor γ (PPARγ) J. Biol. Chem. 272 1997 20230 20235
    • (1997) J. Biol. Chem. , vol.272 , pp. 20230-20235
    • Werman, A.1    Hollenberg, A.2    Solanes, G.3    Bjorbaek, C.4    Vidal-Puig, A.J.5    Flier, J.S.6
  • 8
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • S.S. Deeb, L. Fajas, and M. Nemoto A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity Nat. Genet. 20 1998 284 287
    • (1998) Nat. Genet. , vol.20 , pp. 284-287
    • Deeb, S.S.1    Fajas, L.2    Nemoto, M.3
  • 9
    • 0034607051 scopus 로고    scopus 로고
    • Inhibitory effect of a proline-to alanine substitution at codon 12 of peroxisome proliferator-activated receptor-γ2 on thiazolidinedione-induced adipogenesis
    • J. Masugi, Y. Tamori, H. Mori, Y. Koike, and M. Kasuga Inhibitory effect of a proline-to alanine substitution at codon 12 of peroxisome proliferator-activated receptor-γ2 on thiazolidinedione-induced adipogenesis Biochem. Biophys. Res. Commun. 268 2000 178 182
    • (2000) Biochem. Biophys. Res. Commun. , vol.268 , pp. 178-182
    • Masugi, J.1    Tamori, Y.2    Mori, H.3    Koike, Y.4    Kasuga, M.5
  • 10
    • 17944362462 scopus 로고    scopus 로고
    • Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARγ2) gene in relation to insulin sensitivity among glucose tolerant Caucasians
    • J. Ek, G. Andersen, and S.A. Urhammer Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARγ2) gene in relation to insulin sensitivity among glucose tolerant Caucasians Diabetologia 44 2001 1170 1176
    • (2001) Diabetologia , vol.44 , pp. 1170-1176
    • Ek, J.1    Andersen, G.2    Urhammer, S.A.3
  • 11
    • 0033624575 scopus 로고    scopus 로고
    • The common PPAR-gamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • D. Altshuler, J.N. Hirschhorn, and M. Klannemark The common PPAR-gamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes Nat. Genet. 26 2000 76 80
    • (2000) Nat. Genet. , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 12
    • 0033060302 scopus 로고    scopus 로고
    • Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes
    • F.P. Mancini, O. Vaccaro, and L. Sabatino Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes Diabetes 48 1999 1466 1468
    • (1999) Diabetes , vol.48 , pp. 1466-1468
    • Mancini, F.P.1    Vaccaro, O.2    Sabatino, L.3
  • 13
    • 0033582258 scopus 로고    scopus 로고
    • Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus
    • J. Ringel, S. Engeli, A. Distler, and A.M. Sharma Pro12Ala missense mutation of the peroxisome proliferator activated receptor gamma and diabetes mellitus Biochem. Biophys. Res. Commun. 254 1999 450 453
    • (1999) Biochem. Biophys. Res. Commun. , vol.254 , pp. 450-453
    • Ringel, J.1    Engeli, S.2    Distler, A.3    Sharma, A.M.4
  • 14
    • 0034745184 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: Association with type 2 diabetes and trait differences
    • J.A. Douglas, M.R. Erdos, and R.M. Watanabe The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences Diabetes 50 2001 886 890
    • (2001) Diabetes , vol.50 , pp. 886-890
    • Douglas, J.A.1    Erdos, M.R.2    Watanabe, R.M.3
  • 15
    • 0036074246 scopus 로고    scopus 로고
    • Genetic isolates in East Asia: A study of linkage disequilibrium in the X chromosome
    • T. Kato, S. Mano, and T. Itakura Genetic isolates in East Asia: a study of linkage disequilibrium in the X chromosome Am. J. Hum. Genet. 71 2002 395 400
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 395-400
    • Kato, T.1    Mano, S.2    Itakura, T.3
  • 16
    • 0034745185 scopus 로고    scopus 로고
    • The Pro12Ala substitution in PPAR-γ is associated with resistance to development of diabetes in the general population
    • H. Mori, H. Ikegami, and Y. Kawaguchi The Pro12Ala substitution in PPAR-γ is associated with resistance to development of diabetes in the general population Diabetes 50 2001 891 894
    • (2001) Diabetes , vol.50 , pp. 891-894
    • Mori, H.1    Ikegami, H.2    Kawaguchi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.