Erratum: Candidate gene association study in type 2 diabetes indicates a role for genes involved in β-cell function as well as insulin action (PLoS Biology 1, 1 (45) (DOI: 10.1371/journal.pbio.0000020));Candidate gene association study in type 2 diabetes indicates a role for genes involved in β-cell function as well as insulin action

PLoS Biology

Volumn 1, Issue 1, 2003, Pages

  Barroso, Inês ^a,d   Luan, Jian'an ^b   Middelberg, Rita P S ^b   Harding, Anne Helen ^b   Franks, Paul W ^b   Jakes, Rupert W ^b   Clayton, David ^c   Schafer, Alan J ^a   O'Rahilly, Stephen ^b   Wareham, Nicholas J ^b  

^a Palo Alto CA 94304 USA   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; SULFONYLUREA; ABC TRANSPORTER; DRUG RECEPTOR; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 4; HNF4A PROTEIN, HUMAN; INSULIN RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PHOSPHATIDYLINOSITOL 3 KINASE; POTASSIUM CHANNEL; SLC2A2 PROTEIN, HUMAN; SOS PROTEIN; SULFONYLUREA RECEPTOR;

ADULT; AGED; ALLELE; ARTICLE; CASE CONTROL STUDY; CAUCASIAN; CELL FUNCTION; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HAPLOTYPE; HORMONE ACTION; HUMAN; HUMAN CELL; MALE; MOLECULAR CLONING; MOLECULE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHENOTYPE; PREDICTION; QUANTITATIVE TRAIT; STATISTICAL SIGNIFICANCE; UNITED KINGDOM; BIOLOGICAL MODEL; GENETICS; GENOTYPE; METABOLISM; MIDDLE AGED; PANCREAS ISLET BETA CELL; RISK; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; STATISTICAL MODEL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGED; ATP-BINDING CASSETTE TRANSPORTERS; CASE-CONTROL STUDIES; CLONING, MOLECULAR; DIABETES MELLITUS, TYPE 2; GENOTYPE; GLUCOSE TRANSPORTER TYPE 2; HAPLOTYPES; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MIDDLE AGED; MODELS, GENETIC; MODELS, STATISTICAL; ODDS RATIO; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTOR, INSULIN; RECEPTORS, DRUG; SOS1 PROTEIN;

EID: 4243062602     PISSN: 15449173     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pbio.0000092     Document Type: Erratum

References (100)

1. Almind K, Delahaye L, Hansen T, van Obberghen E, Pedersen O, et al. (2002) Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85α. Proc Natl Acad Sci U S A 99: 2124-2128. Find this article online
2. Alpha B, Cox L, Crowther N, Clark PM, Hales CN (1992) Sensitive amplified immunoenzymometric assays (IEMA) for human insulin and intact proinsulin. Eur J Clin Chem Clin Biochem 30: 27-32. Find this article online
3. Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC, et al. (2000) The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26: 76-80. Find this article online
4. Argyrokastritis A, Kamakari S, Kapsetaki M, Kritis A, Talianidis I, et al. (1997) Human hepatocyte nuclear factor-4 (hHNF-4) gene maps to 20q12-q13.1 between PLCG1 and D20S17. Hum Genet 99: 233-236. Find this article online
5. Baier LJ, Wiedrich C, Hanson RL, Bogardus C (1998) Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85α): Preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women. Diabetes 47: 973-975. Find this article online
6. Baier LJ, Permana PA, Yang X, Pratley RE, Hanson RL, et al. (2000) A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. J Clin Invest 106: R69-R73. Find this article online
7. Baroni MG, Alcolado JC, Pozzilli P, Cavallo MG, Li SR, et al. (1992) Polymorphisms at the GLUT2 (beta-cell/liver) glucose transporter gene and noninsulin-dependent diabetes mellitus (NIDDM): Analysis in affected pedigree members. Clin Genet 41: 229-324. Find this article online
8. Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, et al. (1999) Dominant negative mutations in human PPAR gassociated with severe insulin resistance, diabetes mellitus and hypertension. Nature 402: 880-883. Find this article online
9. Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, et al. (2002) Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 418: 650-654. Find this article online
10. Baynes KC, Beeton CA, Panayotou G, Stein R, Soos M, et al. (2000) Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: A novel variant with impaired insulin-stimulated lipid kinase activity. Diabetologia 43: 321-331. Find this article online
11. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Statist Soc B 57: 289-300. Find this article online
12. Bertrand G, Gross R, Roye M, Ahren B, Ribes G (1992) Evidence for a direct inhibitory effect of PYY on insulin secretion in rats. Pancreas 7: 595-600. Find this article online
13. Bowden DW, Sale M, Howard TD, Qadri A, Spray BJ, et al. (1997) Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy. Diabetes 46: 882-886. Find this article online
14. Chen X, Levine L, Kwok PY (1999) Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res 9: 492-498. Find this article online
15. Chiano MN, Clayton DG (1998) Fine genetic mapping using haplotype analysis and the missing data problem. Ann Hum Genet 62 (Pt 1): 55-60.
16. Cox NJ (2001) Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: Examples from studies of the calpain-10 gene. Hum Mol Genet 10: 2301-2305. Find this article online
17. Daimon M, Oizumi T, Saitoh T, Kameda W, Yamaguchi H, et al. (2002) Calpain 10 gene polymorphisms are related, not to type 2 diabetes, but to increased serum cholesterol in Japanese. Diabetes Res Clin Pract 56: 147-152. Find this article online
18. DuPont WD, Plummer WD (1997) PS power and sample size program. Control Clin Trials 18: 274. Find this article online
19. Ek J, Andersen G, Urhammer SA, Gaede PH, Drivsholm T, et al. (2001) Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus. Diabetologia 44: 2220-2226. Find this article online
20. Elbein SC, Chu W, Ren Q, Hemphill C, Schay J, et al. (2002) Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. J Clin Endocrinol Metab 87: 650-654. Find this article online
21. Esterbauer H, Oberkofler H, Linnemayr V, Iglseder B, Hedegger M, et al. (2002) Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: Associations with obesity indices in middle-aged women. Diabetes 51: 1281-1286. Find this article online
22. Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, et al. (2001) Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom. Am J Hum Genet 69: 544-552. Find this article online
23. Fajans SS, Bell GI, Polonsky KS (2001) Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 345: 971-980. Find this article online
24. Garant MJ, Kao WH, Brancati F, Coresh J, Rami TM, et al. (2002) SNP43 of CAPN10 and the risk of type 2 diabetes in African-Americans: The Atherosclerosis Risk in Communities Study. Diabetes 51: 231-217. Find this article online
25. Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, et al. (1999) Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A 96: 2198-2203. Find this article online
26. Gloyn A, Hashim Y, Ashcroft SJ, Ashfield R, Wiltshire S, et al. (2001) Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53). Diabet Med 18: 206-212. Find this article online
27. Gloyn A, Weedon MN, Owen KR, Turner MJ, Knight BA, et al. (2003) Large-scale association studies of variants in genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with Type 2 diabetes. Diabetes 52: 568-572. Find this article online
28. Gu HF, Almgren P, Lindholm E, Frittitta L, Pizzuti A, et al. (2000) Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis. Diabetes 49: 1601-1603. Find this article online
29. Halsall DJ, McFarlane I, Luan J, Cox TM, Wareham NJ (2003) Typical type 2 diabetes mellitus and HFE gene mutations: A population-based case-control study. Hum Mol Genet 12: 1361-1365. Find this article online
30. + channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians. Diabetologia 41: 1511-1515. Find this article online
31. Hansen L, Hansen T, Vestergaard H, Bjorbaek C, Echwald SM, et al. (1995) A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin. Hum Mol Genet 4: 1313-1320. Find this article online
32. Hansen L, Hansen T, Clausen JO, Echwald SM, Urhammer SA, et al. (1997) The Val985Met insulin-receptor variant in the Danish Caucasian population: Lack of associations with noninsulin-dependent diabetes mellitus or insulin resistance. Am J Hum Genet 60: 1532-1535. Find this article online
33. Hansen L, Reneland R, Berglund L, Rasmussen SK, Hansen T, et al. (2000) Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity. Diabetes 49: 298-301. Find this article online
34. Hansen T, Andersen CB, Echwald SM, Urhammer SA, Clausen JO, et al. (1997) Identification of a common amino acid polymorphism in the p85α regulatory subunit of phosphatidylinositol 3-kinase: Effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index. Diabetes 46: 494-501. Find this article online
35. Hansen T, Echwald SM, Hansen L, Moller AM, Almind K, et al. (1998) Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene. Diabetes 47: 598-605. Find this article online
36. Hansen T, Ambye L, Grarup N, Hansen L, Echwald SM, et al. (2001) Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus. Diabetologia 44: 1330-1334. Find this article online
37. Hara K, Tobe K, Okada T, Kadowaki H, Akanuma Y, et al. (2002) A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes. Diabetologia 45: 740-743. Find this article online
38. Hart LM, Stolk RP, Heine RJ, Grobbee DE, van der Does FE, et al. (1996) Association of the insulin-receptor variant Met-985 with hyperglycemia and noninsulin-dependent diabetes mellitus in The Netherlands: A population-based study. Am J Hum Genet 59: 1119-1125. Find this article online
39. Hart LM, de Knijff P, Dekker JM, Stolk RP, Nijpels G, et al. (1999a) Variants in the sulphonylurea receptor gene: Association of the exon 16-3t variant with Type II diabetes mellitus in Dutch Caucasians. Diabetologia 42: 617-620. Find this article online
40. Hart LM, Stolk RP, Dekker JM, Nijpels G, Grobbee DE, et al. (1999b) Prevalence of variants in candidate genes for type 2 diabetes mellitus in The Netherlands: The Rotterdam study and the Hoorn study. J Clin Endocrinol Metab 84: 1002-1006. Find this article online
41. Hegele RA, Harris SB, Zinman B, Wang J, Cao H, et al. (1998) Variation in the AU(AT)-rich element within the 3′-untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians. J Clin Endocrinol Metab 83: 3980-3983. Find this article online
42. Hegele RA, Harris SB, Zinman B, Hanley AJ, Cao H (2001) Absence of association of type 2 diabetes with CAPN10 and PC-1 polymorphisms in Oji-Cree. Diabetes Care 24: 1498-1499. Find this article online
43. Herzig S, Long F, Jhala US, Hedrick S, Quinn R, et al. (2001) CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413: 179-183. Find this article online
44. Horikawa Y, Iwasaki N, Hara M, Furuta H, Hinokio Y, et al. (1997) Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nat Genet 17: 384-385. Find this article online
45. Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, et al. (2000) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 26: 163-175. Find this article online
46. Huber PJ (1967) The behavior of maximum likelihood estimates under nonstandard conditions. In: Proceedings of the fifth Berkeley symposium on mathematical statistics and probability. Berkeley: University of California Press. 1: 221-233.
47. Huxtable SJ, Saker PJ, Haddad L, Walker M, Frayling TM, et al. (2000) Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles. Diabetes 49: 126-130. Find this article online
48. Inoue H, Ferrer J, Welling CM, Elbein SC, Hoffman M, et al. (1996) Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians. Diabetes 45: 825-831. Find this article online
49. Ji L, Malecki M, Warram JH, Yang Y, Rich SS, et al. (1997) New susceptibility locus for NIDDM is localized to human chromosome 20q. Diabetes 46: 876-881. Find this article online
50. Kawanishi M, Tamori Y, Masugi J, Mori H, Ito C, et al. (1997) Prevalence of a polymorphism of the phosphatidylinositol 3-kinase p85 alpha regulatory subunit (codon 326 Met→Ile) in Japanese NIDDM patients. Diabetes Care 20: 1043. Find this article online
51. King H, Aubert RE, Herman WH (1998) Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections. Diabetes Care 21: 1414-1431. Find this article online
52. Klupa T, Malecki MT, Pezzolesi M, Ji L, Curtis S, et al. (2000) Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2. Diabetes 49: 2212-2216. Find this article online
53. Kunst A, Draeger B, Ziegenhorn J (1983) UV-methods with hexokinase and glucose-6-phosphate dehydrogenase. In: Bergmeyer H, editor. Methods of enzymatic analysis. Weinheim: Verlag Chemie. 163-172.
54. Lacquemant C, Chikri M, Boutin P, Samson C, Froguel P (2002) No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasias. Diabetologia 45: 602-603. Find this article online
55. Lander E, Kruglyak L (1995) Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nat Genet 11: 241-247. Find this article online
56. Lewontin RC (1964) The interaction of selection and linkage. I. General considerations: Heterotic models. Genetics 49: 49-67. Find this article online
57. Li SR, Alcolado JC, Stocks J, Baroni MG, Oelbaum RS, et al. (1991) Genetic polymorphisms at the human liver/islet glucose transporter (GLUT2) gene locus in Caucasian and West Indian subjects with type 2 (noninsulin-dependent) diabetes mellitus. Biochim Biophys Acta 1097: 293-298. Find this article online
58. Love-Gregory LD, Lin J, Skolnick G, Suarez B, Permutt MA (2003) An E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPAR Pro12Ala variant. Diabetologia 46: 136-137. Find this article online
59. Luan J, Browne PO, Harding AH, Halsall DJ, O'Rahilly S, et al. (2001) Evidence for gene-nutrient interaction at the PPARγ locus. Diabetes 50: 686-689. Find this article online
60. Malecki MT, Antonellis A, Casey P, Ji L, Wantman M, et al. (1998) Exclusion of the hepatocyte nuclear factor 4α as a candidate gene for late-onset NIDDM linked with chromosome 20q. Diabetes 47: 970-972. Find this article online
61. Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, et al. (1999) Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus. Nat Genet 23: 323-328. Find this article online
62. Mander AP (2001) Haplotype analysis in population-based association studies. Stata J 1: 58-75.
63. Michael LF, Wu Z, Cheatham RB, Puigserver P, Adelmant G, et al. (2001) Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci U S A 98: 3820-3825. Find this article online
64. Moller AM, Urhammer SA, Dalgaard LT, Reneland R, Berglund L, et al. (1997) Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4α in Caucasians with maturity onset NIDDM. Diabetologia 40: 980-983. Find this article online
65. Moller AM, Jensen NM, Pildal J, Drivsholm T, Borch-Johnsen K, et al. (2001) Studies of genetic variability of the glucose transporter 2 promoter in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab 86: 2181-2186. Find this article online
66. Muller YL, Bogardus C, Pedersen O, Baier L (2003) A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. Diabetes 52: 895-898. Find this article online
67. Nielsen EM, Hansen L, Carstensen B, Echwald SM, Drivsholm T, et al. (2003) The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of Type 2 diabetes. Diabetes 52: 573-577. Find this article online
68. Nieuwenhuizen AG, Karlsson S, Fridolf T, Ahren B (1994) Mechanisms underlying the insulinostatic effect of peptide YY in mouse pancreatic islets. Diabetologia 37: 871-878. Find this article online
69. O'Rahilly S, Choi WH, Patel P, Turner RC, Flier JS, et al. (1991) Detection of mutations in insulin-receptor gene in NIDDM patients by analysis of single-stranded conformation polymorphisms. Diabetes 40: 777-782. Find this article online
70. O'Rahilly S, Krook A, Morgan R, Rees A, Flier JS, et al. (1992) Insulin receptor and insulin-responsive glucose transporter (GLUT4) mutations and polymorphisms in a Welsh Type 2 (noninsulin-dependent) diabetic population. Diabetologia 35: 486-489. Find this article online
71. Permutt MA, Wasson JC, Suarez BK, Lin J, Thomas J, et al. (2001) A genome scan for type 2 diabetes susceptibility loci in a genetically isolated population. Diabetes 50: 681-685. Find this article online
72. Pizzuti A, Frittitta L, Argiolas A, Baratta R, Goldfine ID, et al. (1999) A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance. Diabetes 48: 1881-1884. Find this article online
73. Poulton J, Luan J, Macaulay V, Hennings S, Mitchell J, et al. (2002) Type 2 diabetes is associated with a common mitochondrial variant: Evidence from a population-based case-control study. Hum Mol Genet 11: 1581-1583. Find this article online
74. Price JA, Fossey SC, Sale MM, Brewer CS, Freedman BI, et al. (2000) Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients. Diabetologia 43: 364-372. Find this article online
75. Puigserver P, Wu Z, Park CW, Graves R, Wright M, et al. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92: 829-839. Find this article online
76. Rasmussen SK, Urhammer SA, Pizzuti A, Echwald SM, Ekstrom CT, et al. (2000) The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians. Diabetes 49: 1608-1611. Find this article online
77. Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, et al. (2002) Digenic inheritance of severe insulin resistance in a human pedigree. Nat Genet 31: 379-384. Find this article online
78. Schwanstecher C, Schwanstecher M (2002) Nucleotide sensitivity of pancreatic ATP-sensitive potassium channels and type 2 diabetes. Diabetes 51: Suppl 3 S358-S362. Find this article online
79. Schwanstecher C, Meyer U, Schwanstecher M (2002) K(IR)6.2 polymorphism predisposes to type 2 diabetes by inducing overactivity of pancreatic beta-cell ATP-sensitive K(+) channels. Diabetes 51: 875-879. Find this article online
80. Shih DQ, Dansky HM, Fleisher M, Assmann G, Fajans SS, et al. (2000) Genotype/phenotype relationships in HNF-4 α/MODY1: Haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels. Diabetes 49: 832-837. Find this article online
81. Sobey WJ, Beer SF, Carrington CA, Clark PM, Frank BH, et al. (1989) Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins. Biochem J 260: 535-541. Find this article online
82. Standing SJ, Taylor RP (1992) Glycated haemoglobin: An assessment of high capacity liquid chromatographic and immunoassay methods. Ann Clin Biochem 29: 494-505. Find this article online
83. Stoffel M, Duncan SA (1997) The maturity-onset diabetes of the young (MODY1) transcription factor HNF4α regulates expression of genes required for glucose transport and metabolism. Proc Natl Acad Sci U S A 94: 13209-13214. Find this article online
84. Stoffers DA, Ferrer J, Clarke WL, Habener JF (1997) Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat Genet 17: 138-139. Find this article online
85. Tanizawa Y, Riggs AC, Chiu KC, Janssen RC, Bell DS, et al. (1994) Variability of the pancreatic islet beta cell/liver (GLUT2) glucose transporter gene in NIDDM patients. Diabetologia 37: 420-427. Find this article online
86. Thorpe KL, Schafer AJ, Genin E, Trowsdale J, Beck S (1999) Detection of polymorphism in the RING3 gene by high-throughput fluorescent SSCP analysis. Immunogenetics 49: 256-265. Find this article online
87. Tsai HJ, Sun G, Weeks DE, Kaushal R, Wolujewicz M, et al. (2001) Type 2 diabetes and three calpain-10 gene polymorphisms in Samoans: No evidence of association. Am J Hum Genet 69: 1236-1244. Find this article online
88. Vega RB, Huss JM, Kelly DP (2000) The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol Cell Biol 20: 1868-1876. Find this article online
89. Vionnet N, Stoffel M, Takeda J, Yasuda K, Bell GI, et al. (1992) Nonsense mutation in the glucokinase gene causes early-onset noninsulin-dependent diabetes mellitus. Nature 356: 721-722. Find this article online
90. Wareham NJ, Byrne CD, Williams R, Day NE, Hales CN (1999) Fasting proinsulin concentrations predict the development of type 2 diabetes. Diabetes Care 22: 262-270. Find this article online
91. Weyer C, Bogardus C, Mott DM, Pratley RE (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104: 787-794. Find this article online
92. White HA (1980) Heteroskedasticity-consistent covariance matrix estimator and a direct test for heteroskedasticity. Econometrica 48: 817-830. Find this article online
93. White HA (1982) Maximum likelihood estimation of misspecified models. Econometrica 50: 1-25. Find this article online
94. Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, et al. (1999) Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 98: 115-124. Find this article online
95. Xia J, Scherer SW, Cohen PT, Majer M, Xi T, et al. (1998) A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes. Diabetes 47: 1519-1524. Find this article online
96. Yamagata K, Furuta H, Oda N, Kaisaki PJ, Menzel S, et al. (1996a) Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1). Nature 384: 458-460. Find this article online
97. Yamagata K, Oda N, Kaisaki PJ, Menzel S, Furuta H, et al. (1996b) Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3). Nature 384: 455-458. Find this article online
98. Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, et al. (2001) Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413: 131-138. Find this article online
99. Zimmet P (1982) Type 2 (noninsulin-dependent) diabetes: An epidemiological overview. Diabetologia 22: 399-411. Find this article online
100. Zouali H, Hani EH, Philippi A, Vionnet N, Beckmann JS, et al. (1997) A susceptibility locus for early-onset noninsulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene. Hum Mol Genet 6: 1401-1408. Find this article online