Role of programmed cell death in normal neuronal development and function

Anatomical Science International

Volumn 79, Issue 4, 2004, Pages 191-197

  Buss, Robert R ^a   Oppenheim, Ronald W ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Development; Genetic mutants; Nervous system

Indexed keywords

APOPTOSIS; BRAIN DEVELOPMENT; CAENORHABDITIS ELEGANS; CELL FUNCTION; DROSOPHILA MELANOGASTER; EMBRYO MORTALITY; GENE MUTATION; GLIA CELL; MOTOR CONTROL; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSORY NERVE CONDUCTION;

EID: 10944222754     PISSN: 14476959     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1447-073x.2004.00088.x     Document Type: Review

References (73)

1. Abdelilah S, Mountcastle-Shah E, Harvey M et al. (1996) Mutations affecting neural survival in the zebrafish Danio rerio. Development 123, 217-27.
2. Abrams JM, White K, Fessler LI, Steller H (1993) Programmed cell death during Drosophila embryogenesis. Development 117, 29-43.
3. Avery L, Horvitz HR (1987) A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant. Cell 51, 1071-8.
4. Bangs P, White K (2000) Regulation and execution of apoptosis during Drosophila development. Dev Dynam 218, 68-79.
5. Bar-Peled O, Knudson M, Korsmeyer SJ, Rothstein JD (1999) Motor neuron degeneration is attenuated in Bax-deficient neurons in vitro. J Neurosci Res 55, 542-56.
6. Biehlmaier O, Neuhauss SCF, Kohler K (2001) Onset and time course of apoptosis in the developing zebrafish retina. Cell Tissue Res 306, 199-207.
7. Brachmann CB, Jassim OW, Wachsmuth BD, Cagan RL (2000) The Drosophila Bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation. Curr Biol 10, 547-50.
8. Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P (1998) Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94, 727-37.
9. Cole LK, Ross LS (2001) Apoptosis in the developing zebrafish embryo. Dev Biol 240, 123-42.
10. Colussi PA, Quinn LM, Huang DCS et al. (2000) Debcl, a proapoptotic bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery. J Cell Biol 148, 703-14.
11. Conradt B, Horvitz HR (1988) The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9. Cell 93, 519-29.
12. Deckwerth TL, Johnson EM (1993) Temporal analysis of events associated with programmed cell death (Apoptosis) of sympathetic neurons deprived of nerve growth factor. J Cell Biol 123, 1207-22.
13. Deckwerth TL, Elliot JL, Knudson CM, Johnson EM, Snider WD, Korsmeyer SJ (11996) Bax is required for neuronal death after trophic factor deprivation and during development. Neuron 17, 401-11.
14. Deckwerth TL, Easton RM, Knudson CM, Korsmeyer SJ, Johnson EM (1998) Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation. Exp Neurol 152, 150-62.
15. Dong R, Jacobs JR (1997) Origin and differentiation of supernumerary midline glia in Drosophila embryos deficient for apoptosis. Dev Biol 190, 165-77.
16. Draizen TA, Ewer J, Robinow S (1999) Genetic and hormonal regulation of the death of peptidergic neurons in the Drosophila central nervous system. J Neurobiol 38, 455-65.
17. Easton RM, Deckwerth TL, Parsadanian AS, Johnson EM (1997) Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: A phenotype indistinguishable from Bax deletion. J Neurosci 17, 9656-66.
18. Ellis HM, Horvitz HR (1986) Genetic control of programmed cell death in the nematode C. elegans. Cell 44, 817-29.
19. Ellis RE, Yuan J, Horvitz HR (1991) Mechanisms and functions of cell death. Annu Rev Cell Biol 7, 663-98.
20. Estus S, Zaks WJ, Freeman RS, Gruda M, Bravo R, Johnson EM (1994) Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis. J Cell Biol 127, 1717-27.
21. Fan H, Favero M, Vogel MW (2001) Elimination of bax expression in mice increases cerebellar Purkinje cell numbers but not the number of granule cells. J Comp Neurol 436, 82-91.
22. Farlie PG, Dringen R, Rees SM, Kannourakis G, Bernard O (1995) bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc Natl Acad Sci USA 92 4397-401.
23. Furutani-Seiki M, Jaing Y, Brand M et al. (1996) Neural degeneration mutants in the zebrafish, Danio rerio. Development 123, 229-39.
24. Garcia I, Martinou I, Tsujimoto Y, Martinou JC (1992) Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258, 302-4.
25. Gianfranceschi L, Fiorentini A, Maffei L (1999) Behavioural visual acuity of wild type and bcl2 transgenic mouse. Vis Res 39, 569-74.
26. Gonzalez-Garcia M, Garcia I, Ding L (1995) bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proc Natl Acad Sci USA 92, 4304-8.
27. Greenlund LJS, Korsmeyer SJ, Johnson EM (1995) Role of BCL-2 in the survival and function of developing and mature sympathetic neurons. Neuron 15, 649-61.
28. Hay BA, Wolff T, Rubin GM (1994) Expression of baculovirus P35 prevents cell death in Drosophila. Development 120, 2121-9.
29. Hengartner MO, Ellis RE, Horvitz HR (1992) Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature 356, 494-9.
30. Honarpour N, Du C, Richardson JA (2000) Adult Apaf-1-deficient mice exhibit male infertility. Dev Biol 218, 248-59.
31. Inohara N, Nunez G (2000) Genes with homology to mammalian apoptosis regulators identified in zebrafish. Cell Death Differ 7, 509-10.
32. Jiang C, Baehrecke EH, Thummel CS (1997) Steriod regulated programmed cell death during Drosophila metamorphosis. Development 124, 4673-83.
33. Kanuka H, Sawamoto K, Inohara N, Matsuno K, Okano H, Miura M (1999) Control of the cell death pathway by Dapaf-1, a Drosophila Apaf-1/CED-4-related caspase activator. Mol Cell 4, 757-69.
34. Kimura K, Truman JW (1990) Postmetamorphic cell death in the nervous and muscular systems of Drosophila melanogaster. J Neurosci 10, 403-11.
35. Kinugasa T, Ozaki S, Hamanaka S, Kudo N (2002) The effects of sciatic nerve axotomy on spinal motoneurons in neonatal bax-deficient mice. Neurosci Res 44, 439-46.
36. Kuida K, Lippke JA, Ku G et al. (1995) Altered cytokine export and apoptosis in mice deficient in interieukin-1α converting enzyme. Science 267, 2000-3.
37. Kuida K, Zheng TS, Na S et al. (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384, 368-72.
38. Kuida K, Haydar TF, Kuan C et al. (1998) Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94, 325-37.
39. Li P, Allen H, Banerjee S et al. (1995) Mice deficient in IL-1α-converting enzyme are defective in production of mature IL-1α and resistant to endotoxic shock. Cell 80, 401-11.
40. Lindsten T, Ross AJ, King A et al. (2000) The combined functions of proapoptotic bcl-2 family members bak and bax are essential for normal development of multiple tissues. Mol Cell 6, 1389-99.
41. Martinou JC, Dubois-Dauphin M, Staple JK et al. (1994) Over-expression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 13, 1017-30.
42. Miller TM, Moulder KL, Knudson CM et al. (1997) Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J Cell Biol 139, 205-17.
43. Oppenheim RW (1999) Programmed cell death. In: Fundamental Neuroscience (Zigmond M, Bloom FE, Landis SC et al. eds). Academic Press, New York, 581-610.
44. Oppenheim RW, Flavell RA, Vinsant S, Prevette D, Kuan C, Rakic P (2001) Programmed cell death of developing mammalian neurons after genetic deletion of caspases. J Neurosci 21, 4752-60.
45. L is an antiapoptotic regulator for postnatal CNS neurons. J Neurosci 18, 1009-19.
46. Patel TD, Jackman A, Rice FL, Kucera J, Snider WD (2000) Development of sensory neurons in the absence of NGF/TrkA signaling in vivo. Neuron 25, 345-57.
47. Patel TD, Kramer I, Kucera J et al. (2003) Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents. Neuron 38, 403-16.
48. Pequignot MO, Provost AC, Salle S et al. (2003) Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina. Dev Dyn 228, 231-8.
49. Peterson C, Carney GE, Taylor BJ, White K (2002) reaper is required for neuroblast apoptosis during Drosophila development. Development 129, 1467-76.
50. Porciatti V, Pizzorusso T, Maffei L (1999) Vision in mice with neuronal redundancy due to inhibition of developmental cell death. Vis Neurosci 16, 721-6.
51. Quinn L, Coombe M, Mills K et al. (2003) Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions. EMBO J 22, 3568-79.
52. Richardson H, Kumar S (2002) Death to flies: Drosophila as a model to study programmed cell death. J Immunol Methods 265 21-38.
53. Rodriguez A, Oliver H, Zou H, Chen P, Wang X, Abrams JM (1999) Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway. Nat Cell Biol 1 272-9.
54. Rodriguez A, Chen P, Oliver H, Abrams JM (2002) Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog Dark. EMBO J 21, 2189-97.
55. Rondi-Reig L, Mariani J (2002) To die or not to die, does it change the function? Behavior of transgenic mice reveals a role for developmental cell death. Brain Res Bull 57, 85-91.
56. Rondi-Reig L, Dubreuil YL, Martinou JC, Delhaye-Bouchaud N, Caston J, Mariani J (1997) Fear decrease in transgenic mice overexpressing bcl-2 in neurons. Neuroreport 8, 2429-32.
57. Rondi-Reig L, Lohof A, Dubreuil YL et al. (1999) Hu-Bcl-2 transgenic mice with supernumerary neurons exhibit timing impairment in a complex motor task. Eur J Neurosci 11, 2285-90.
58. Rondi-Reig L, Lemaigre-Dubreuil Y, Montecot C et al. (2001) Transgenic mice with neuronal overexpression of BCL-2 gene present navigation disabilities in a water task. Neuroscience 104, 207-15.
59. Sun W, Gould TW, Vinsant S, Prevette D, Oppenheim RM (2003) Neuromuscular development after the prevention of naturally occurring neuronal death by bax deletion. J Neurosci 23, 7298-310.
60. Truman JW (1984) Cell death in invertebrate nervous systems. Annu Rev Neurosci 7, 171-88.
61. Truman JW, Thorn RS, Robinow S (1992) Programmed neuronal death in insect development. J Neurobiol 23, 1295-311.
62. Werth JL, Deshmukh M, Cocabo J, Johnson EM, Rothman SM (2000) Reversible physiological alterations in sympathetic neurons devoid of NGF but protected from apoptosis by caspase inhibition or Bax deletion. Exp Neurol 161, 203-11.
63. White FA, Keller-Peck CR, Knudson CM, Korsmeyer SJ, Snider WD (1998) Widespread elimination of naturally occurring neuronal death in bax-deficient mice. J Neurosci 18, 1428-39.
64. White JG, Southgate E, Thomson JN (1991) On the nature of undead cells in the nematode Caenorhabditis elegans. Philos Trans R Soc Lond B Biol Sci 331, 263-71.
65. White K, Grether ME, Abrams JM, Young L, Farrel K, Stellar H (1994) Genetic control of programmed cell death in Drosophila. Science 264, 677-83.
66. Yin VP, Thummel CS (2004) A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila. Proc Natl Acad Sci USA 101, 8022-7.
67. Yoshida H, Kong Y, Yoshida R et al. (1998) Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94, 739-50.
68. Zanjani HS, Vogel MW, Delhaye-Bouchaud N, Martinou JC, Mariani J (1996) Increased cerebellar Purkinje cell numbers in mice overexpressing the human bcl-2 transgene. J Comp Neurol 374, 332-41.
69. Zanjani HS, Vogel MW, Delhaye-Bouchaud N, Martinou JC, Mariani J (1997) Increased inferior olivary neuron and cerebellar granule numbers in transgenic mice overexpressing the human bcl-2 gene. J Neurobiol 32, 502-16.
70. Zanjani H, Lemaigre-Dubreuil Y, Niranjala JK et al. (2004) Cerebellar Purkinje cell loss in aging Hu-Bcl-2 transgenic mice. J Comp Neurol 475, 481-92.
71. Zhou L, Hashimi H, Schwartz LM, Nambu JR (1995) Programmed cell death in the Drosophila central nervous system midline. Curr Biol 5, 784-90.
72. Zhou L, Song Z, Tittel J, Stellar H (1999) HAC-1, a Drosophila homologue of APAF-1 and CED-4, functions in developmental and radiation-induced apoptosis. Mol Cell 4, 745-55.
73. Zup SL, Carrier H, Waters EM et al. (2003) Overexpression of bcl-2 reduces sex differences in neuron number in the brain and spinal cord. J Neurosci 23, 2357-62.