-
2
-
-
28644432882
-
Comparative genomic analysis of human and chimpanzee proteases
-
Puente XS, Gutierrez-Fernandez A, Ordonez GR, Hillier LW, Lopez-Otin C. Comparative genomic analysis of human and chimpanzee proteases. Genomics 2005; 86(6): 638-47.
-
(2005)
Genomics
, vol.86
, Issue.6
, pp. 638-647
-
-
Puente, X.S.1
Gutierrez-Fernandez, A.2
Ordonez, G.R.3
Hillier, L.W.4
Lopez-Otin, C.5
-
3
-
-
0025212267
-
Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases
-
Reynolds DS, Stevens RL, Lane WS, Carr MH, Austen KF, Serafin WE. Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases. Proc Natl Acad Sci USA 1990; 87: 3230-4.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3230-3234
-
-
Reynolds, D.S.1
Stevens, R.L.2
Lane, W.S.3
Carr, M.H.4
Austen, K.F.5
Serafin, W.E.6
-
4
-
-
0028046879
-
Genes for mast-cell serine protease and their molecular evolution
-
Huang R, Hellman L. Genes for mast-cell serine protease and their molecular evolution. Immunogenetics 1994; 40: 397-414.
-
(1994)
Immunogenetics
, vol.40
, pp. 397-414
-
-
Huang, R.1
Hellman, L.2
-
5
-
-
0039649450
-
Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations
-
Lutzelschwab C, Pejler G, Aveskogh M, Hellman L. Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations. J Exp Med 1997; 185: 13-29.
-
(1997)
J Exp Med
, vol.185
, pp. 13-29
-
-
Lutzelschwab, C.1
Pejler, G.2
Aveskogh, M.3
Hellman, L.4
-
6
-
-
0036034837
-
New developments in the genetics and activation of mast cell proteases
-
Caughey GH. New developments in the genetics and activation of mast cell proteases. Mol Immunol 2002; 38: 1353-7.
-
(2002)
Mol Immunol
, vol.38
, pp. 1353-1357
-
-
Caughey, G.H.1
-
7
-
-
0347445722
-
A genomic analysis of rat proteases and protease inhibitors
-
Puente XS, Lopez-Otin C. A genomic analysis of rat proteases and protease inhibitors. Genome Res 2004; 14: 609-22.
-
(2004)
Genome Res
, vol.14
, pp. 609-622
-
-
Puente, X.S.1
Lopez-Otin, C.2
-
8
-
-
0034659960
-
Characterization of human γ-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families
-
Caughey GH, Raymond WW, Blount JL et al. Characterization of human γ-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families. J Immunol 2000; 164: 6566-75.
-
(2000)
J Immunol
, vol.164
, pp. 6566-6575
-
-
Caughey, G.H.1
Raymond, W.W.2
Blount, J.L.3
-
9
-
-
13544256359
-
Mastin is a gelatinolytic mast cell peptidase resembling a mini-proteasome
-
Raymond WW, Sommerhoff CP, Caughey GH. Mastin is a gelatinolytic mast cell peptidase resembling a mini-proteasome. Arch Biochem Biophys 2005; 435: 311-22.
-
(2005)
Arch Biochem Biophys
, vol.435
, pp. 311-322
-
-
Raymond, W.W.1
Sommerhoff, C.P.2
Caughey, G.H.3
-
10
-
-
0024299058
-
Purification and characterization of dog mastocytoma chymase. Identification of an octapeptide conserved in chymotryptic leukocyte proteases
-
Caughey GH, Viro NF, Lazarus SC, Nadel JA. Purification and characterization of dog mastocytoma chymase. Identification of an octapeptide conserved in chymotryptic leukocyte proteases. Biochim Biophys Acta 1988; 952: 142-9.
-
(1988)
Biochim Biophys Acta
, vol.952
, pp. 142-149
-
-
Caughey, G.H.1
Viro, N.F.2
Lazarus, S.C.3
Nadel, J.A.4
-
12
-
-
0141957399
-
A despecialization step underlying evolution of a family of serine proteases
-
Wouters MA, Liu K, Riek P, Husain A. A despecialization step underlying evolution of a family of serine proteases. Mol Cell 2003; 12: 343-54.
-
(2003)
Mol Cell
, vol.12
, pp. 343-354
-
-
Wouters, M.A.1
Liu, K.2
Riek, P.3
Husain, A.4
-
13
-
-
0024465841
-
Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases
-
Jenne DE, Masson D, Zimmer M, Haefliger J-A, Li W-H, Tschopp J. Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases. Biochemistry 1989; 28: 7953-61.
-
(1989)
Biochemistry
, vol.28
, pp. 7953-7961
-
-
Jenne, D.E.1
Masson, D.2
Zimmer, M.3
Haefliger, J.-A.4
Li, W.-H.5
Tschopp, J.6
-
14
-
-
0026032178
-
Structure and evolutionary origin of the human granzyme H gene
-
Haddad P, Jenne D, Tschopp J, Clement MV, Mathieu-Mahul D, Sasportes M. Structure and evolutionary origin of the human granzyme H gene. Int Immunol 1991; 3: 57-66.
-
(1991)
Int Immunol
, vol.3
, pp. 57-66
-
-
Haddad, P.1
Jenne, D.2
Tschopp, J.3
Clement, M.V.4
Mathieu-Mahul, D.5
Sasportes, M.6
-
15
-
-
0033525211
-
Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3
-
Pallaoro M, Fejzo MS, Shayesteh L, Blount JL, Caughey GH. Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3. J Biol Chem 1999; 274: 3355-62.
-
(1999)
J Biol Chem
, vol.274
, pp. 3355-3362
-
-
Pallaoro, M.1
Fejzo, M.S.2
Shayesteh, L.3
Blount, J.L.4
Caughey, G.H.5
-
16
-
-
0035987309
-
Genetic deficiency of human mast cell α-tryptase
-
Soto D, Malmsten C, Blount JL, Muilenburg DJ, Caughey GH. Genetic deficiency of human mast cell α-tryptase. Clin Exp Allergy 2002; 32: 1000-6.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 1000-1006
-
-
Soto, D.1
Malmsten, C.2
Blount, J.L.3
Muilenburg, D.J.4
Caughey, G.H.5
-
17
-
-
0027415378
-
The human mast cell chymase gene (CMA1): Mapping to the cathepsin G /granzyme gene cluster and lineage-restricted expression
-
Caughey GH, Schaumberg TH, Zerweck EH, et al. The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression. Genomics 1993; 15: 614-20.
-
(1993)
Genomics
, vol.15
, pp. 614-620
-
-
Caughey, G.H.1
Schaumberg, T.H.2
Zerweck, E.H.3
-
18
-
-
0033538454
-
Human tryptases α and β/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft
-
Huang C, Li L, Krilis SA, et al. Human tryptases α and β/II are functionally distinct due, in part, to a single amino acid difference in one of the surface loops that forms the substrate-binding cleft. J Biol Chem 1999; 274: 19670-6.
-
(1999)
J Biol Chem
, vol.274
, pp. 19670-19676
-
-
Huang, C.1
Li, L.2
Krilis, S.A.3
-
19
-
-
0036385841
-
The crystal structure of human α1-tryptase reveals a blocked substrate-binding region
-
Marquardt U, Zettl F, Huber R, Bode W, Sommerhoff C. The crystal structure of human α1-tryptase reveals a blocked substrate-binding region. J Mol Biol 2002; 321: 491-502.
-
(2002)
J Mol Biol
, vol.321
, pp. 491-502
-
-
Marquardt, U.1
Zettl, F.2
Huber, R.3
Bode, W.4
Sommerhoff, C.5
-
20
-
-
0036446159
-
Rodent alpha-chymases are elastase-like proteases
-
Kunori Y, Koizumi M, Masegi T, et al. Rodent alpha-chymases are elastase-like proteases. Eur J Biochem 2002; 269: 5921-30.
-
(2002)
Eur J Biochem
, vol.269
, pp. 5921-5930
-
-
Kunori, Y.1
Koizumi, M.2
Masegi, T.3
-
21
-
-
0141960165
-
Extended substrate specificity of rat mast cell protease 5, a rodent α-chymase with elastase-like primary specificity
-
Karlson U, Pejler G, Tomasini-Johansson B, Hellman L. Extended substrate specificity of rat mast cell protease 5, a rodent α-chymase with elastase-like primary specificity. J Biol Chem 2003; 278: 39625-31.
-
(2003)
J Biol Chem
, vol.278
, pp. 39625-39631
-
-
Karlson, U.1
Pejler, G.2
Tomasini-Johansson, B.3
Hellman, L.4
-
22
-
-
0025835534
-
Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase
-
Caughey GH, Zerweck EH, Vanderslice P. Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase. J Biol Chem 1991; 266: 12956-63.
-
(1991)
J Biol Chem
, vol.266
, pp. 12956-12963
-
-
Caughey, G.H.1
Zerweck, E.H.2
Vanderslice, P.3
-
23
-
-
0031279354
-
Cloning and expression of the dog mast cell α-chymase gene
-
Caughey GH, Blount JL, Koerber KL, Kitamura M, Fang KC. Cloning and expression of the dog mast cell α-chymase gene. J Immunol 1997; 159: 4367-75.
-
(1997)
J Immunol
, vol.159
, pp. 4367-4375
-
-
Caughey, G.H.1
Blount, J.L.2
Koerber, K.L.3
Kitamura, M.4
Fang, K.C.5
-
24
-
-
0025368035
-
Human mast cell tryptase: Multiple cDNAs and genes reveal a multigene serine protease family
-
Vanderslice P, Ballinger SM, Tam EK, Goldstein SM, Craik CS, Caughey GH. Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family. Proc Natl Acad Sci USA 1990; 87: 3811-5.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3811-3815
-
-
Vanderslice, P.1
Ballinger, S.M.2
Tam, E.K.3
Goldstein, S.M.4
Craik, C.S.5
Caughey, G.H.6
-
25
-
-
1642576098
-
Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns
-
Wong GW, Yasuda S, Morokawa N, Li L, Stevens RL. Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns. J Biol Chem 2004; 279: 2438-52.
-
(2004)
J Biol Chem
, vol.279
, pp. 2438-2452
-
-
Wong, G.W.1
Yasuda, S.2
Morokawa, N.3
Li, L.4
Stevens, R.L.5
-
26
-
-
0000317053
-
Chloroacyl esters as histochemical substrates
-
Gomori G. Chloroacyl esters as histochemical substrates. J Histochem Cytochem 1953; 1: 469-70.
-
(1953)
J Histochem Cytochem
, vol.1
, pp. 469-470
-
-
Gomori, G.1
-
27
-
-
0000452039
-
Histochemical demonstration of a species-specific trypsin-like enzyme in mast cells
-
Glenner GG, Cohen LA. Histochemical demonstration of a species-specific trypsin-like enzyme in mast cells. Nature 1960; 185: 846-7.
-
(1960)
Nature
, vol.185
, pp. 846-847
-
-
Glenner, G.G.1
Cohen, L.A.2
-
28
-
-
0037432314
-
Structure of human pro-chymase: A model for the activating transition of granule-associated proteases
-
Reiling KY, Krucinski J, Miercke LJ, Raymond WW, Caughey GH, Stroud RM. Structure of human pro-chymase: a model for the activating transition of granule-associated proteases. Biochemistry 2003; 42: 2616-24.
-
(2003)
Biochemistry
, vol.42
, pp. 2616-2624
-
-
Reiling, K.Y.1
Krucinski, J.2
Miercke, L.J.3
Raymond, W.W.4
Caughey, G.H.5
Stroud, R.M.6
-
29
-
-
0032546934
-
Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I
-
Wolters PJ, Raymond WW, Blount JL, Caughey GH. Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I. J Biol Chem 1998; 273: 15514-20.
-
(1998)
J Biol Chem
, vol.273
, pp. 15514-15520
-
-
Wolters, P.J.1
Raymond, W.W.2
Blount, J.L.3
Caughey, G.H.4
-
30
-
-
0034088336
-
Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways
-
Wolters PJ, Laig-Webster M, Caughey GH. Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways. Am J Respir Cell Mol Biol 2000; 22: 183-90.
-
(2000)
Am J Respir Cell Mol Biol
, vol.22
, pp. 183-190
-
-
Wolters, P.J.1
Laig-Webster, M.2
Caughey, G.H.3
-
31
-
-
0027518670
-
Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I
-
McGuire MJ, Lipsky PE, Thiele DL. Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I. J Biol Chem 1993; 268: 2458-67.
-
(1993)
J Biol Chem
, vol.268
, pp. 2458-2467
-
-
McGuire, M.J.1
Lipsky, P.E.2
Thiele, D.L.3
-
32
-
-
0033587689
-
Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo
-
Pham CT, Ley TJ. Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. Proc Natl Acad Sci USA 1999; 96: 8627-32.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8627-8632
-
-
Pham, C.T.1
Ley, T.J.2
-
33
-
-
0035947568
-
Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice
-
Wolters PJ, Pham CT, Muilenburg DJ, Ley TJ, Caughey GH. Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice. J Biol Chem 2001; 276: 18551-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 18551-18556
-
-
Wolters, P.J.1
Pham, C.T.2
Muilenburg, D.J.3
Ley, T.J.4
Caughey, G.H.5
-
34
-
-
0036168150
-
Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis
-
Adkison AM, Raptis SZ, Kelley DG, Pham CT. Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. J Clin Invest 2002; 109: 363-71.
-
(2002)
J Clin Invest
, vol.109
, pp. 363-371
-
-
Adkison, A.M.1
Raptis, S.Z.2
Kelley, D.G.3
Pham, C.T.4
-
35
-
-
0033455594
-
Mutations of the cathepsin C gene are responsible for Papillon-Lefevre syndrome
-
Hart TC, Hart PS, Bowden DW, et al. Mutations of the cathepsin C gene are responsible for Papillon-Lefevre syndrome. J Med Genet 1999; 36: 881-7.
-
(1999)
J Med Genet
, vol.36
, pp. 881-887
-
-
Hart, T.C.1
Hart, P.S.2
Bowden, D.W.3
-
36
-
-
4444343709
-
Loss-of-function mutations in cathepsin C in two families with Papillon-Lefevre syndrome are associated with deficiency of serine proteinases in PMNs
-
de Haar SF, Jansen DC, Schoenmaker T, De Vree H, Everts V, Beertsen W. Loss-of-function mutations in cathepsin C in two families with Papillon-Lefevre syndrome are associated with deficiency of serine proteinases in PMNs. Hum Mutat 2004; 23: 524.
-
(2004)
Hum Mutat
, vol.23
, pp. 524
-
-
de Haar, S.F.1
Jansen, D.C.2
Schoenmaker, T.3
De Vree, H.4
Everts, V.5
Beertsen, W.6
-
37
-
-
10344234724
-
Papillon-Lefevre syndrome: Correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans
-
Pham CT, Ivanovich JL, Raptis SZ, Zehnbauer B, Ley TJ. Papillon-Lefevre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans. J Immunol 2004; 173: 7277-81.
-
(2004)
J Immunol
, vol.173
, pp. 7277-7281
-
-
Pham, C.T.1
Ivanovich, J.L.2
Raptis, S.Z.3
Zehnbauer, B.4
Ley, T.J.5
-
38
-
-
0030068941
-
A novel heparin-dependent processing pathway for human tryptase: Autocatalysis followed by activation with dipeptidyl peptidase I
-
Sakai K, Ren S, Schwartz LB. A novel heparin-dependent processing pathway for human tryptase: autocatalysis followed by activation with dipeptidyl peptidase I. J Clin Invest 1996; 97: 988-95.
-
(1996)
J Clin Invest
, vol.97
, pp. 988-995
-
-
Sakai, K.1
Ren, S.2
Schwartz, L.B.3
-
39
-
-
0010234421
-
Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells
-
Le Trong H, Neurath H, Woodbury RG. Substrate specificity of the chymotrypsin-like protease in secretory granules isolated from rat mast cells. Proc Natl Acad Sci USA 1987; 84: 364-7.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 364-367
-
-
Le Trong, H.1
Neurath, H.2
Woodbury, R.G.3
-
40
-
-
0026518944
-
Protease composition of exocytosed human skin mast cell protease-proteoglycan complexes: Tryptase resides in a complex distinct from chymase and carboxypeptidase
-
Goldstein SM, Leong J, Schwartz LB, Cooke D. Protease composition of exocytosed human skin mast cell protease-proteoglycan complexes: tryptase resides in a complex distinct from chymase and carboxypeptidase. J Immunol 1992; 148: 2475-82.
-
(1992)
J Immunol
, vol.148
, pp. 2475-2482
-
-
Goldstein, S.M.1
Leong, J.2
Schwartz, L.B.3
Cooke, D.4
-
41
-
-
0021148042
-
Human lung tryptase. Purification and characterization
-
Smith TJ, Hougland MW, Johnson DA. Human lung tryptase. Purification and characterization. J Biol Chem 1984; 259: 11046-51.
-
(1984)
J Biol Chem
, vol.259
, pp. 11046-11051
-
-
Smith, T.J.1
Hougland, M.W.2
Johnson, D.A.3
-
42
-
-
0022872843
-
Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer
-
Schwartz LB, Bradford TR. Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer. J Biol Chem 1986; 261: 7372-9.
-
(1986)
J Biol Chem
, vol.261
, pp. 7372-7379
-
-
Schwartz, L.B.1
Bradford, T.R.2
-
43
-
-
0028865394
-
Cell surface-bound elastase and cathepsin G on human neutrophils: A novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases
-
Owen CA, Campbell MA, Sannes PL, Boukedes SS, Campbell EJ. Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases. J Cell Biol 1995; 131: 775-89.
-
(1995)
J Cell Biol
, vol.131
, pp. 775-789
-
-
Owen, C.A.1
Campbell, M.A.2
Sannes, P.L.3
Boukedes, S.S.4
Campbell, E.J.5
-
44
-
-
0031939933
-
Angiotensin II generation at the cell surface of activated neutrophils: Novel cathepsin G-mediated catalytic activity that is resistant to inhibition
-
Owen CA, Campbell EJ. Angiotensin II generation at the cell surface of activated neutrophils: novel cathepsin G-mediated catalytic activity that is resistant to inhibition. J Immunol 1998; 160: 1436-43.
-
(1998)
J Immunol
, vol.160
, pp. 1436-1443
-
-
Owen, C.A.1
Campbell, E.J.2
-
45
-
-
23844554460
-
Inhibition of neutrophil elastase by α1-protease inhibitor at the surface of human polymorphonuclear neutrophils
-
Korkmaz B, Attucci S, Jourdan ML, Juliano L, Gauthier F. Inhibition of neutrophil elastase by α1-protease inhibitor at the surface of human polymorphonuclear neutrophils. J Immmunol 2005; 175: 3329-38.
-
(2005)
J Immmunol
, vol.175
, pp. 3329-3338
-
-
Korkmaz, B.1
Attucci, S.2
Jourdan, M.L.3
Juliano, L.4
Gauthier, F.5
-
46
-
-
0032741435
-
Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COON-terminal hydrophobic extension
-
Wong GW, Tang Y, Feyfant E, et al. Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COON-terminal hydrophobic extension. J Biol Chem 1999; 274: 30784-93.
-
(1999)
J Biol Chem
, vol.274
, pp. 30784-30793
-
-
Wong, G.W.1
Tang, Y.2
Feyfant, E.3
-
47
-
-
0036830570
-
Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13 /interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway
-
Wong GW, Foster PS, Yasuda S, et al. Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway. J Biol Chem 2002; 277: 41906-15.
-
(2002)
J Biol Chem
, vol.277
, pp. 41906-41915
-
-
Wong, G.W.1
Foster, P.S.2
Yasuda, S.3
-
48
-
-
0035863818
-
Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes
-
Skokos D, Le Panse S, Villa I, et al. Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes. J Immunol 2001; 166: 868-76.
-
(2001)
J Immunol
, vol.166
, pp. 868-876
-
-
Skokos, D.1
Le Panse, S.2
Villa, I.3
-
49
-
-
0037443410
-
Mast cell-derived exosomes induce phenotypic and fractional maturation of dendritic cells and elicit specific immune responses in vivo
-
Skokos D, Botros HG, Demeure C, et al. Mast cell-derived exosomes induce phenotypic and fractional maturation of dendritic cells and elicit specific immune responses in vivo. J Immunol 2003; 170: 3037-45.
-
(2003)
J Immunol
, vol.170
, pp. 3037-3045
-
-
Skokos, D.1
Botros, H.G.2
Demeure, C.3
-
50
-
-
0034665315
-
Bioactive proteinase 3 on the cell surface of human neutrophils: Quantification, catalytic activity, and susceptibility to inhibition
-
Campbell EJ, Campbell MA, Owen CA. Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition. J Immunol 2000; 165: 3366-74.
-
(2000)
J Immunol
, vol.165
, pp. 3366-3374
-
-
Campbell, E.J.1
Campbell, M.A.2
Owen, C.A.3
-
51
-
-
0348143307
-
Membrane proteinase 3 expression on resting neutrophils as a pathogenic factor in PR3-ANCA-associated vasculitis
-
van Rossum AP, Limburg PC, Kallenberg CG. Membrane proteinase 3 expression on resting neutrophils as a pathogenic factor in PR3-ANCA-associated vasculitis. Clin Exp Rheumatol 2003; 21: S64-8.
-
(2003)
Clin Exp Rheumatol
, vol.21
-
-
van Rossum, A.P.1
Limburg, P.C.2
Kallenberg, C.G.3
-
52
-
-
0033557766
-
Structural basis of profactor D activation: From a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D
-
Jing H, Macon KJ, Moore D, DeLucas LJ, Volanakis JE, Narayana SV. Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D. EMBO J 1999; 18: 804-14.
-
(1999)
EMBO J
, vol.18
, pp. 804-814
-
-
Jing, H.1
Macon, K.J.2
Moore, D.3
DeLucas, L.J.4
Volanakis, J.E.5
Narayana, S.V.6
-
53
-
-
0032500627
-
Structures of native and complexed complement factor D: Implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity
-
Jing H, Babu YS, Moore D, et al. Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity. J Mol Biol 1998; 282: 1061-81.
-
(1998)
J Mol Biol
, vol.282
, pp. 1061-1081
-
-
Jing, H.1
Babu, Y.S.2
Moore, D.3
-
54
-
-
2642600031
-
Human β-tryptase is a ring-like tetramer with active sites facing a central pore
-
Pereira PJB, Bergner A, Macedo-Ribeiro S, et al. Human β-tryptase is a ring-like tetramer with active sites facing a central pore. Nature 1998; 392: 306-11.
-
(1998)
Nature
, vol.392
, pp. 306-311
-
-
Pereira, P.J.B.1
Bergner, A.2
Macedo-Ribeiro, S.3
-
55
-
-
0029042981
-
Purification and characterization of dog mast cell protease-3, an oligomeric relative of tryptases
-
Raymond WW, Tam EK, Blount JL, Caughey GH. Purification and characterization of dog mast cell protease-3, an oligomeric relative of tryptases. J Biol Chem 1995; 270: 13164-70.
-
(1995)
J Biol Chem
, vol.270
, pp. 13164-13170
-
-
Raymond, W.W.1
Tam, E.K.2
Blount, J.L.3
Caughey, G.H.4
-
56
-
-
0038392751
-
The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity
-
Bell JK, Goetz DH, Mahrus S, Harris JL, Fletterick RJ, Craik CS. The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity. Nat Struct Biol 2003; 10: 527-34.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 527-534
-
-
Bell, J.K.1
Goetz, D.H.2
Mahrus, S.3
Harris, J.L.4
Fletterick, R.J.5
Craik, C.S.6
-
57
-
-
0038730744
-
Crystal structure of the apoptosis-inducing human granzyme A dimer
-
Hink-Schauer C, Estebanez-Perpina E, Kurschus FC, Bode W, Jenne DE. Crystal structure of the apoptosis-inducing human granzyme A dimer. Nat Struct Biol 2003; 10: 535-40.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 535-540
-
-
Hink-Schauer, C.1
Estebanez-Perpina, E.2
Kurschus, F.C.3
Bode, W.4
Jenne, D.E.5
-
58
-
-
0019321009
-
Kinetics of association of serine proteinases with native and oxidized α1-proteinase inhibitor and α1-antichymotrypsin
-
Beatty K, Bieth J, Travis J. Kinetics of association of serine proteinases with native and oxidized α1-proteinase inhibitor and α1-antichymotrypsin. J Biol Chem 1980; 255: 3931-4.
-
(1980)
J Biol Chem
, vol.255
, pp. 3931-3934
-
-
Beatty, K.1
Bieth, J.2
Travis, J.3
-
59
-
-
0024558667
-
Alpha 1-antitrypsin deficiency: Lessons learned from the bedside to the gene and back again. Historic perspectives
-
Eriksson S. Alpha 1-antitrypsin deficiency: lessons learned from the bedside to the gene and back again. Historic perspectives. Chest 1989; 95: 181-9.
-
(1989)
Chest
, vol.95
, pp. 181-189
-
-
Eriksson, S.1
-
60
-
-
0030465416
-
A 30-year perspective on alpha 1-antitrypsin deficiency
-
Eriksson S. A 30-year perspective on alpha 1-antitrypsin deficiency. Chest 1996; 110: 237S-42S.
-
(1996)
Chest
, vol.110
-
-
Eriksson, S.1
-
61
-
-
0037011795
-
Alpha1-antitrypsin deficiency--a model for conformational diseases
-
Carrell RW, Lomas DA. Alpha1-antitrypsin deficiency--a model for conformational diseases. N Engl J Med 2002; 346: 45-53.
-
(2002)
N Engl J Med
, vol.346
, pp. 45-53
-
-
Carrell, R.W.1
Lomas, D.A.2
-
62
-
-
4744356921
-
Alpha-1-antitrypsin deficiency: Diagnosis and treatment
-
Perlmutter DH. Alpha-1-antitrypsin deficiency: diagnosis and treatment. Clin Liver Dis 2004; 8: 839-59.
-
(2004)
Clin Liver Dis
, vol.8
, pp. 839-859
-
-
Perlmutter, D.H.1
-
63
-
-
0027328108
-
A leucine-to-proline substitution causes a defective α1-antichymotrypsin allele associated with familial obstructive lung disease
-
Poller W, Faber JP, Weidinger S, et al. A leucine-to-proline substitution causes a defective α1-antichymotrypsin allele associated with familial obstructive lung disease. Genomics 1993; 17: 740-3.
-
(1993)
Genomics
, vol.17
, pp. 740-743
-
-
Poller, W.1
Faber, J.P.2
Weidinger, S.3
-
64
-
-
0027169598
-
The molecular basis of α1-antichymotrypsin deficiency in a heterozygote with liver and lung disease
-
Faber JP, Poller W, Olek K, et al. The molecular basis of α1-antichymotrypsin deficiency in a heterozygote with liver and lung disease. J Hepatol 1993; 18: 313-21.
-
(1993)
J Hepatol
, vol.18
, pp. 313-321
-
-
Faber, J.P.1
Poller, W.2
Olek, K.3
-
65
-
-
0024849646
-
Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors
-
Schechter NM, Sprows JL, Schoenberger OL, Lazarus GS, Cooperman BS, Rubin H. Reaction of human skin chymotrypsin-like proteinase chymase with plasma proteinase inhibitors. J Biol Chem 1989; 264: 21308-15.
-
(1989)
J Biol Chem
, vol.264
, pp. 21308-21315
-
-
Schechter, N.M.1
Sprows, J.L.2
Schoenberger, O.L.3
Lazarus, G.S.4
Cooperman, B.S.5
Rubin, H.6
-
66
-
-
0028990678
-
Granzyme B plays a critical role in cytotoxic lymphocyte-induced apoptosis
-
Shresta S, Heusel JW, Macivor DM, Wesselschmidt RL, Russell JH, Ley TJ. Granzyme B plays a critical role in cytotoxic lymphocyte-induced apoptosis. Immunol Rev 1995; 146: 211-21.
-
(1995)
Immunol Rev
, vol.146
, pp. 211-221
-
-
Shresta, S.1
Heusel, J.W.2
Macivor, D.M.3
Wesselschmidt, R.L.4
Russell, J.H.5
Ley, T.J.6
-
67
-
-
0035284891
-
The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites
-
Bladergroen BA, Strik MC, Bovenschen N, et al. The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites. J Immunol 2001; 166: 3218-25.
-
(2001)
J Immunol
, vol.166
, pp. 3218-3225
-
-
Bladergroen, B.A.1
Strik, M.C.2
Bovenschen, N.3
-
68
-
-
17444408171
-
The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells
-
Bladergroen BA, Strik MC, Wolbink AM, et al. The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells. Eur J Immunol 2005; 35: 1175-83.
-
(2005)
Eur J Immunol
, vol.35
, pp. 1175-1183
-
-
Bladergroen, B.A.1
Strik, M.C.2
Wolbink, A.M.3
-
69
-
-
0026042309
-
Expression of the secretory leukoprotease inhibitor gene in epithelial cells
-
Abe T, Kobayashi N, Yoshimura K, et al. Expression of the secretory leukoprotease inhibitor gene in epithelial cells. J Clin Invest 1991; 87: 2207-15.
-
(1991)
J Clin Invest
, vol.87
, pp. 2207-2215
-
-
Abe, T.1
Kobayashi, N.2
Yoshimura, K.3
-
70
-
-
0027471301
-
Distribution of secretory leukoprotease inhibitor in the human nasal airway
-
Lee CH, Igarashi Y, Hohman RJ, Kaulbach H, White MV, Kaliner MA. Distribution of secretory leukoprotease inhibitor in the human nasal airway. Am Rev Respir Dis 1993; 147: 710-6.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 710-716
-
-
Lee, C.H.1
Igarashi, Y.2
Hohman, R.J.3
Kaulbach, H.4
White, M.V.5
Kaliner, M.A.6
-
71
-
-
0023736418
-
Alveolar fluid neutrophil elastase activity in the adult respiratory distress syndrome is complexed to α2-macroglobulin
-
Wewers MD, Herzyk DJ, Gadek JE. Alveolar fluid neutrophil elastase activity in the adult respiratory distress syndrome is complexed to α2-macroglobulin. J Clin Invest 1988; 82: 1260-7.
-
(1988)
J Clin Invest
, vol.82
, pp. 1260-1267
-
-
Wewers, M.D.1
Herzyk, D.J.2
Gadek, J.E.3
-
72
-
-
0346847766
-
Albumin is a substrate of human chymase: Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site
-
Raymond WW, Ruggles S, Craik CS, Caughey GH. Albumin is a substrate of human chymase: Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site. J Biol Chem 2003; 278(36): 34517-24.
-
(2003)
J Biol Chem
, vol.278
, Issue.36
, pp. 34517-34524
-
-
Raymond, W.W.1
Ruggles, S.2
Craik, C.S.3
Caughey, G.H.4
-
73
-
-
0020312338
-
Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases
-
Reilly CF, Tewksbury DA, Schechter NB, Travis J. Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases. J Biol Chem 1982; 257: 8619-22.
-
(1982)
J Biol Chem
, vol.257
, pp. 8619-8622
-
-
Reilly, C.F.1
Tewksbury, D.A.2
Schechter, N.B.3
Travis, J.4
-
74
-
-
0025598309
-
Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart
-
Urata H, Kinoshita A, Misono KS, Bumpus FM, Husain A. Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart. J Biol Chem 1990; 265: 22348-57.
-
(1990)
J Biol Chem
, vol.265
, pp. 22348-22357
-
-
Urata, H.1
Kinoshita, A.2
Misono, K.S.3
Bumpus, F.M.4
Husain, A.5
-
76
-
-
0030838414
-
Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces
-
Dell'Italia LJ, Meng QC, Balcells E, et al. Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces. J Clin Invest 1997; 100: 253-8.
-
(1997)
J Clin Invest
, vol.100
, pp. 253-258
-
-
Dell'Italia, L.J.1
Meng, Q.C.2
Balcells, E.3
-
77
-
-
0032575271
-
Specificity of human cathepsin G
-
Polanowska J, Krokoszynska I, Czapinska H, Watorek W, Dadlez M, Otlewski J. Specificity of human cathepsin G. Biochim Biophys Acta 1998; 1386: 189-98.
-
(1998)
Biochim Biophys Acta
, vol.1386
, pp. 189-198
-
-
Polanowska, J.1
Krokoszynska, I.2
Czapinska, H.3
Watorek, W.4
Dadlez, M.5
Otlewski, J.6
-
78
-
-
0031057649
-
Sheep mast cell proteinase-1: Characterization as a member of a new class of dual-specific ruminant chymases
-
Pemberton AD, Huntley JF, Miller HR. Sheep mast cell proteinase-1: characterization as a member of a new class of dual-specific ruminant chymases. Biochem J 1997; 321: 665-70.
-
(1997)
Biochem J
, vol.321
, pp. 665-670
-
-
Pemberton, A.D.1
Huntley, J.F.2
Miller, H.R.3
-
79
-
-
0017812965
-
Covalent structure of a group-specific protease from rat small intestine
-
Woodbury RG, Katunuma N, Kobayashi K, Titani K, Neurath H. Covalent structure of a group-specific protease from rat small intestine. Biochemistry 1978; 17: 811-9.
-
(1978)
Biochemistry
, vol.17
, pp. 811-819
-
-
Woodbury, R.G.1
Katunuma, N.2
Kobayashi, K.3
Titani, K.4
Neurath, H.5
-
80
-
-
0023774994
-
The structure of rat mast cell protease II at 1.9-Å resolution
-
Remington SJ, Woodbury RG, Reynolds RA, Matthews BW, Neurath H. The structure of rat mast cell protease II at 1.9-Å resolution. Biochemistry 1988; 27: 8097-145.
-
(1988)
Biochemistry
, vol.27
, pp. 8097-8145
-
-
Remington, S.J.1
Woodbury, R.G.2
Reynolds, R.A.3
Matthews, B.W.4
Neurath, H.5
-
81
-
-
0030711516
-
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9Å
-
McGrath ME, Mirzadegan T, Schmidt BF. Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9Å. Biochemistry 1997; 36: 14318-24.
-
(1997)
Biochemistry
, vol.36
, pp. 14318-14324
-
-
McGrath, M.E.1
Mirzadegan, T.2
Schmidt, B.F.3
-
82
-
-
0033547878
-
The 2.2 Å crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phechloromethylketone: Structural explanation for its dipeptidyl carboxypeptidase specificity
-
Pereira PJB, Wang ZM, Rubin H, et al. The 2.2 Å crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phechloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity. J Mol Biol 1999; 286: 163-73.
-
(1999)
J Mol Biol
, vol.286
, pp. 163-173
-
-
Pereira, P.J.B.1
Wang, Z.M.2
Rubin, H.3
-
83
-
-
0027401683
-
Three-dimensional models of four mouse mast cell chymases. Identification of proteoglycan binding regions and protease-specific antigenic epitopes
-
Sali A, Matsumoto R, McNeil HP, Karplus M, Stevens RL. Three-dimensional models of four mouse mast cell chymases. Identification of proteoglycan binding regions and protease-specific antigenic epitopes. J Biol Chem 1993; 268: 9023-34.
-
(1993)
J Biol Chem
, vol.268
, pp. 9023-9034
-
-
Sali, A.1
Matsumoto, R.2
McNeil, H.P.3
Karplus, M.4
Stevens, R.L.5
-
84
-
-
0037193192
-
Lys40 but not Arg143 influences selectivity of angiotensin conversion by human α-chymase
-
Muilenburg DJ, Raymond WW, Wolters PJ, Caughey GH. Lys40 but not Arg143 influences selectivity of angiotensin conversion by human α-chymase. Biochim Biophys Acta 2002; 1596: 346-56.
-
(2002)
Biochim Biophys Acta
, vol.1596
, pp. 346-356
-
-
Muilenburg, D.J.1
Raymond, W.W.2
Wolters, P.J.3
Caughey, G.H.4
-
85
-
-
0002451901
-
Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-Å resolution
-
Navia MA, McKeever BM, Springer JP, et al. Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-Å resolution. Proc Natl Acad Sci USA 1989; 86: 7-11.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7-11
-
-
Navia, M.A.1
McKeever, B.M.2
Springer, J.P.3
-
86
-
-
0029853820
-
The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: A Janus-faced proteinase with two opposite specificities
-
Hof P, Mayr I, Huber R et al. The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities. EMBO J 1996; 15: 5481-91.
-
(1996)
EMBO J
, vol.15
, pp. 5481-5491
-
-
Hof, P.1
Mayr, I.2
Huber, R.3
-
87
-
-
0033818886
-
The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity
-
Waugh SM, Harris JL, Fletterick R, Craik CS. The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity. Nat Struct Biol 2000; 7: 762-5.
-
(2000)
Nat Struct Biol
, vol.7
, pp. 762-765
-
-
Waugh, S.M.1
Harris, J.L.2
Fletterick, R.3
Craik, C.S.4
-
88
-
-
0037184613
-
The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features
-
Hink-Schauer C, Estebanez-Perpina E, Wilharm E, et al. The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features. J Biol Chem 2002; 277: 50923-33.
-
(2002)
J Biol Chem
, vol.277
, pp. 50923-50933
-
-
Hink-Schauer, C.1
Estebanez-Perpina, E.2
Wilharm, E.3
-
89
-
-
0037066138
-
Diverse stability and catalytic properties of human tryptase α and β isoforms are mediated by residue differences at the S1 Pocket
-
Selwood T, Wang ZM, McCaslin DR, Schechter NM. Diverse stability and catalytic properties of human tryptase α and β isoforms are mediated by residue differences at the S1 Pocket. Biochemistry 2002; 41: 3329-40.
-
(2002)
Biochemistry
, vol.41
, pp. 3329-3340
-
-
Selwood, T.1
Wang, Z.M.2
McCaslin, D.R.3
Schechter, N.M.4
-
90
-
-
0029888610
-
A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1
-
Smyth MJ, O'Connor MD, Trapani JA, Kershaw MH, Brinkworth RI. A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1. J Immunol 1996; 156: 4174-81.
-
(1996)
J Immunol
, vol.156
, pp. 4174-4181
-
-
Smyth, M.J.1
O'Connor, M.D.2
Trapani, J.A.3
Kershaw, M.H.4
Brinkworth, R.I.5
-
91
-
-
0024349230
-
Adipsin and complement factor D activity: An immune-related defect in obesity
-
Rosen BS, Cook KS, Yaglon J, et al. Adipsin and complement factor D activity: An immune-related defect in obesity. Science 1989; 244: 1483-7.
-
(1989)
Science
, vol.244
, pp. 1483-1487
-
-
Rosen, B.S.1
Cook, K.S.2
Yaglon, J.3
-
92
-
-
0026794743
-
Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue
-
White ET, Damm D, Hancock N, et al. Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. J Biol Chem 1992; 267: 9210-3.
-
(1992)
J Biol Chem
, vol.267
, pp. 9210-9213
-
-
White, E.T.1
Damm, D.2
Hancock, N.3
-
93
-
-
0034885408
-
Murine hypodense eosinophils induce tumour cell apoptosis by a granzyme B-dependent mechanism
-
Costain DJ, Guha AK, Liwski RS, Lee TD. Murine hypodense eosinophils induce tumour cell apoptosis by a granzyme B-dependent mechanism. Cancer Immunol Immunother 2001; 50: 293-9.
-
(2001)
Cancer Immunol Immunother
, vol.50
, pp. 293-299
-
-
Costain, D.J.1
Guha, A.K.2
Liwski, R.S.3
Lee, T.D.4
-
94
-
-
0023126197
-
Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells
-
Schwartz LB, Irani A-MA, Roller K, Castells MC, Schechter NM. Quantitation of histamine, tryptase, and chymase in dispersed human T and TC mast cells. J Immunol 1987; 138: 2611-5.
-
(1987)
J Immunol
, vol.138
, pp. 2611-2615
-
-
Schwartz, L.B.1
Irani, A.-M.A.2
Roller, K.3
Castells, M.C.4
Schechter, N.M.5
-
95
-
-
3042795013
-
Expression of α-tryptase and β-tryptase by human basophils
-
Jogie-Brahim S, Min HK, Fukuoka Y, Xia HZ, Schwartz LB. Expression of α-tryptase and β-tryptase by human basophils. J Allergy Clin Immunol 2004; 113: 1086-92.
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 1086-1092
-
-
Jogie-Brahim, S.1
Min, H.K.2
Fukuoka, Y.3
Xia, H.Z.4
Schwartz, L.B.5
-
96
-
-
0024430531
-
Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity
-
Campbell EJ, Silverman EK, Campbell MA. Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity. J Immunol 1989; 143: 2961-8.
-
(1989)
J Immunol
, vol.143
, pp. 2961-2968
-
-
Campbell, E.J.1
Silverman, E.K.2
Campbell, M.A.3
-
97
-
-
0025144597
-
Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell
-
Schechter NM, Irani AM, Sprows JL, Abernethy J, Wintroub B, Schwartz LB. Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell. J Immunol 1990; 145: 2652-61.
-
(1990)
J Immunol
, vol.145
, pp. 2652-2661
-
-
Schechter, N.M.1
Irani, A.M.2
Sprows, J.L.3
Abernethy, J.4
Wintroub, B.5
Schwartz, L.B.6
-
99
-
-
0024474186
-
Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and antichymase antibodies
-
Irani AM, Bradford TR, Kepley CL, Schechter NM, Schwartz LB. Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and antichymase antibodies. J Histochem Cytochem 1989; 37: 1509-15.
-
(1989)
J Histochem Cytochem
, vol.37
, pp. 1509-1515
-
-
Irani, A.M.1
Bradford, T.R.2
Kepley, C.L.3
Schechter, N.M.4
Schwartz, L.B.5
-
100
-
-
0042377711
-
The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes
-
Edwards KM, Kam CM, Powers JC, Trapani JA. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes. J Biol Chem 1999; 274: 30468-73.
-
(1999)
J Biol Chem
, vol.274
, pp. 30468-30473
-
-
Edwards, K.M.1
Kam, C.M.2
Powers, J.C.3
Trapani, J.A.4
-
101
-
-
0031836105
-
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
-
Belaaouaj A, McCarthy R, Baumann M, et al. Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat Med 1998; 4: 615-8.
-
(1998)
Nat Med
, vol.4
, pp. 615-618
-
-
Belaaouaj, A.1
McCarthy, R.2
Baumann, M.3
-
102
-
-
0034682860
-
Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase
-
Belaaouaj A, Kim KS, Shapiro SD. Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase. Science 2000; 289: 1185-8.
-
(2000)
Science
, vol.289
, pp. 1185-1188
-
-
Belaaouaj, A.1
Kim, K.S.2
Shapiro, S.D.3
-
103
-
-
0037007656
-
Neutrophil elastase targets virulence factors of enterobacteria
-
Weinrauch Y, Drujan D, Shapiro SD, Weiss J, Zychlinsky A. Neutrophil elastase targets virulence factors of enterobacteria. Nature 2002; 417: 91-4.
-
(2002)
Nature
, vol.417
, pp. 91-94
-
-
Weinrauch, Y.1
Drujan, D.2
Shapiro, S.D.3
Weiss, J.4
Zychlinsky, A.5
-
104
-
-
0033986322
-
A critical role for neutrophil elastase in experimental bullous pemphigoid
-
Liu Z, Shapiro SD, Zhou X, et al. A critical role for neutrophil elastase in experimental bullous pemphigoid. J Clin Invest 2000; 105: 113-23.
-
(2000)
J Clin Invest
, vol.105
, pp. 113-123
-
-
Liu, Z.1
Shapiro, S.D.2
Zhou, X.3
-
106
-
-
0034117111
-
Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by α1-antitrypsin
-
Dhami R, Gilks B, Xie C, Zay K, Wright JL, Churg A. Acute cigarette smoke-induced connective tissue breakdown is mediated by neutrophils and prevented by α1-antitrypsin. Am J Respir Cell Mol Biol 2000; 22: 244-52.
-
(2000)
Am J Respir Cell Mol Biol
, vol.22
, pp. 244-252
-
-
Dhami, R.1
Gilks, B.2
Xie, C.3
Zay, K.4
Wright, J.L.5
Churg, A.6
-
107
-
-
0344413022
-
Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice
-
Shapiro SD, Goldstein NM, Houghton AM, Kobayashi DK, Kelley D, Belaaouaj A. Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am J Pathol 2003; 163: 2329-35.
-
(2003)
Am J Pathol
, vol.163
, pp. 2329-2335
-
-
Shapiro, S.D.1
Goldstein, N.M.2
Houghton, A.M.3
Kobayashi, D.K.4
Kelley, D.5
Belaaouaj, A.6
-
108
-
-
0036800045
-
Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs
-
Wright JL, Farmer SG, Churg A. Synthetic serine elastase inhibitor reduces cigarette smoke-induced emphysema in guinea pigs. Am J Respir Crit Care Med 2002; 166: 954-60.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 954-960
-
-
Wright, J.L.1
Farmer, S.G.2
Churg, A.3
-
109
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997; 277: 2002-4.
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
110
-
-
0035807813
-
Complement activation in factor D-deficient mice
-
Xu Y, Ma M, Ippolito GC, Schroeder HW, Jr., Carroll MC, Volanakis JE. Complement activation in factor D-deficient mice. Proc Natl Acad Sci USA 2001; 98: 14577-82.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 14577-14582
-
-
Xu, Y.1
Ma, M.2
Ippolito, G.C.3
Schroeder Jr., H.W.4
Carroll, M.C.5
Volanakis, J.E.6
-
111
-
-
0032763069
-
Normal neutrophil function in cathepsin G-deficient mice
-
MacIvor DM, Shapiro SD, Pham CT, Belaaouaj A, Abraham SN, Ley TJ. Normal neutrophil function in cathepsin G-deficient mice. Blood 1999; 94: 4282-93.
-
(1999)
Blood
, vol.94
, pp. 4282-4293
-
-
MacIvor, D.M.1
Shapiro, S.D.2
Pham, C.T.3
Belaaouaj, A.4
Abraham, S.N.5
Ley, T.J.6
-
112
-
-
20444433960
-
Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering
-
Raptis SZ, Shapiro SD, Simmons PM, Cheng AM, Pham CT. Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering. Immunity 2005; 22: 679-91.
-
(2005)
Immunity
, vol.22
, pp. 679-691
-
-
Raptis, S.Z.1
Shapiro, S.D.2
Simmons, P.M.3
Cheng, A.M.4
Pham, C.T.5
-
113
-
-
0034684681
-
Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1
-
Knight PA, Wright SH, Lawrence CE, Paterson YY, Miller HR. Delayed expulsion of the nematode Trichinella spiralis in mice lacking the mucosal mast cell-specific granule chymase, mouse mast cell protease-1. J Exp Med 2000; 192: 1849-56.
-
(2000)
J Exp Med
, vol.192
, pp. 1849-1856
-
-
Knight, P.A.1
Wright, S.H.2
Lawrence, C.E.3
Paterson, Y.Y.4
Miller, H.R.5
-
114
-
-
0029995317
-
Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase
-
Fang KC, Raymond WW, Lazarus SC, Caughey GH. Dog mastocytoma cells secrete a 92-kD gelatinase activated extracellularly by mast cell chymase. J Clin Invest 1996; 97: 1589-96.
-
(1996)
J Clin Invest
, vol.97
, pp. 1589-1596
-
-
Fang, K.C.1
Raymond, W.W.2
Lazarus, S.C.3
Caughey, G.H.4
-
115
-
-
0035865351
-
Mast cell tissue inhibitor of metalloproteinase-1 is cleaved and inactivated extracellularly by α-chymase
-
Frank BT, Rossall JC, Caughey GH, Fang KC. Mast cell tissue inhibitor of metalloproteinase-1 is cleaved and inactivated extracellularly by α-chymase. J Immunol 2001; 166: 2783-92.
-
(2001)
J Immunol
, vol.166
, pp. 2783-2792
-
-
Frank, B.T.1
Rossall, J.C.2
Caughey, G.H.3
Fang, K.C.4
-
116
-
-
0033151608
-
Inflammatory mast cells upregulate angiogenesis during squamous epithelial carcinogenesis
-
Coussens LM, Raymond WW, Bergers G et al. Inflammatory mast cells upregulate angiogenesis during squamous epithelial carcinogenesis. Genes Develop 1999; 13: 1382-97.
-
(1999)
Genes Develop
, vol.13
, pp. 1382-1397
-
-
Coussens, L.M.1
Raymond, W.W.2
Bergers, G.3
-
117
-
-
15744388309
-
A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2
-
Tchougounova E, Lundequist A, Fajardo I, Winberg JO, Abrink M, Pejler G. A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J Biol Chem 2005; 280: 9291-6.
-
(2005)
J Biol Chem
, vol.280
, pp. 9291-9296
-
-
Tchougounova, E.1
Lundequist, A.2
Fajardo, I.3
Winberg, J.O.4
Abrink, M.5
Pejler, G.6
-
118
-
-
0035830852
-
Altered processing of fibronectin in mice lacking heparin. A role for heparin-dependent mast cell chymase in fibronectin degradation
-
Tchougounova E, Forsberg E, Angelborg G, Kjellen L, Pejler G. Altered processing of fibronectin in mice lacking heparin. A role for heparin-dependent mast cell chymase in fibronectin degradation. J Biol Chem 2001; 276: 3772-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 3772-3777
-
-
Tchougounova, E.1
Forsberg, E.2
Angelborg, G.3
Kjellen, L.4
Pejler, G.5
-
119
-
-
0002079441
-
Mast cell chymases and tryptases: Phylogeny, family relations and biogenesis
-
In: Caughey GH, editor. New York: Marcel Dekker
-
Caughey GH. Mast cell chymases and tryptases: Phylogeny, family relations and biogenesis. In: Caughey GH, editor. Mast Cell Proteases in Immunology and Biology. New York: Marcel Dekker, 1995. pp. 305-29.
-
(1995)
Mast Cell Proteases in Immunology and Biology
, pp. 305-329
-
-
Caughey, G.H.1
-
120
-
-
21044433149
-
Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle
-
Abonia JP, Friend DS, Austen WG, Jr., et al. Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle. J Immunol 2005; 174: 7285-91.
-
(2005)
J Immunol
, vol.174
, pp. 7285-7291
-
-
Abonia, J.P.1
Friend, D.S.2
Austen Jr., W.G.3
-
121
-
-
1642337351
-
Mast cell dipeptidyl peptidase I mediates survival from sepsis
-
Mallen-St Clair J, Pham CT, Villalta SA, Caughey GH, Wolters PJ. Mast cell dipeptidyl peptidase I mediates survival from sepsis. J Clin Invest 2004; 113: 628-34.
-
(2004)
J Clin Invest
, vol.113
, pp. 628-634
-
-
Mallen-St Clair, J.1
Pham, C.T.2
Villalta, S.A.3
Caughey, G.H.4
Wolters, P.J.5
-
122
-
-
0027982477
-
Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse
-
Ghildyal N, Friend DS, Freelund R, et al. Lack of expression of the tryptase mouse mast cell protease 7 in mast cells of the C57BL/6J mouse. J Immunol 1994; 153: 2624-30.
-
(1994)
J Immunol
, vol.153
, pp. 2624-2630
-
-
Ghildyal, N.1
Friend, D.S.2
Freelund, R.3
-
123
-
-
0024501073
-
Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs
-
Sekizawa K, Caughey GH, Lazarus SC, Gold WM, Nadel JA. Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs. J Clin Invest 1989; 83: 175-9.
-
(1989)
J Clin Invest
, vol.83
, pp. 175-179
-
-
Sekizawa, K.1
Caughey, G.H.2
Lazarus, S.C.3
Gold, W.M.4
Nadel, J.A.5
-
124
-
-
0029815507
-
Inhaled tryptase causes bronchoconstriction in sheep via histamine release
-
Molinari JF, Scuri M, Moore WR, Clark J, Tanaka R, Abraham WM. Inhaled tryptase causes bronchoconstriction in sheep via histamine release. Am J Respir Crit Care Med 1996; 154: 649-53.
-
(1996)
Am J Respir Crit Care Med
, vol.154
, pp. 649-653
-
-
Molinari, J.F.1
Scuri, M.2
Moore, W.R.3
Clark, J.4
Tanaka, R.5
Abraham, W.M.6
-
125
-
-
0031023694
-
Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus
-
Johnson PRA, Ammit AJ, Carlin SM, Armour CL, Caughey GH, Black JL. Mast cell tryptase potentiates histamine-induced contraction in human sensitized bronchus. Eur Resp J 1997; 10: 38-43.
-
(1997)
Eur Resp J
, vol.10
, pp. 38-43
-
-
Johnson, P.R.A.1
Ammit, A.J.2
Carlin, S.M.3
Armour, C.L.4
Caughey, G.H.5
Black, J.L.6
-
126
-
-
0035013541
-
Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma
-
Krishna MT, Chauhan A, Little L, et al. Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma. J Allergy Clin Immunol 2001; 107: 1039-45.
-
(2001)
J Allergy Clin Immunol
, vol.107
, pp. 1039-1045
-
-
Krishna, M.T.1
Chauhan, A.2
Little, L.3
-
127
-
-
0037083293
-
Tryptase inhibition blocks airway inflammation in a mouse asthma model
-
Oh S-W, Pae CI, Lee D-K, et al. Tryptase inhibition blocks airway inflammation in a mouse asthma model. J Immunol 2002; 168: 1992-2000.
-
(2002)
J Immunol
, vol.168
, pp. 1992-2000
-
-
Oh, S.-W.1
Pae, C.I.2
Lee, D.-K.3
-
128
-
-
0029088944
-
Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice
-
De Sanctis GT, Merchant M, Beier DR, et al. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat Genet 1995; 11: 150-4.
-
(1995)
Nat Genet
, vol.11
, pp. 150-154
-
-
De Sanctis, G.T.1
Merchant, M.2
Beier, D.R.3
-
129
-
-
0035854794
-
Evaluation of the substrate specificity of human mast cell tryptase βI and demonstration of its importance in bacterial infections of the lung
-
Huang C, De Sanctis GT, O'Brien PJ, et al. Evaluation of the substrate specificity of human mast cell tryptase βI and demonstration of its importance in bacterial infections of the lung. J Biol Chem 2001; 276: 26276-84.
-
(2001)
J Biol Chem
, vol.276
, pp. 26276-26284
-
-
Huang, C.1
De Sanctis, G.T.2
O'Brien, P.J.3
-
130
-
-
0029981928
-
Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α
-
Malaviya R, Ikeda T, Ross E, Abraham SN. Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α. Nature 1996; 381: 77-80.
-
(1996)
Nature
, vol.381
, pp. 77-80
-
-
Malaviya, R.1
Ikeda, T.2
Ross, E.3
Abraham, S.N.4
-
131
-
-
31944437499
-
Mast cells protect mice from mycoplasma pneumonia
-
Xu X, Zhang D, Lyubynska N, et al. Mast cells protect mice from mycoplasma pneumonia. Am J Respir Crit Care Med 2006; 173: 219-25.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 219-225
-
-
Xu, X.1
Zhang, D.2
Lyubynska, N.3
-
132
-
-
0029083438
-
Granzyme A-deficient mice retain potent cell-mediated toxicity
-
Ebnet K, Hausmann M, Lehmann-Grube F, et al. Granzyme A-deficient mice retain potent cell-mediated toxicity. EMBO J. 1995; 14: 4230-9.
-
(1995)
EMBO J.
, vol.14
, pp. 4230-4239
-
-
Ebnet, K.1
Hausmann, M.2
Lehmann-Grube, F.3
-
133
-
-
0030723209
-
In vitro- and ex vivo-derived cytolytic leukocytes from granzyme AxB double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells
-
Simon MM, Hausmann M, Tran T, et al. In vitro- and ex vivo-derived cytolytic leukocytes from granzyme AxB double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells. J Exp Med 1997; 186: 1781-6.
-
(1997)
J Exp Med
, vol.186
, pp. 1781-1786
-
-
Simon, M.M.1
Hausmann, M.2
Tran, T.3
-
134
-
-
0028258577
-
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
-
Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 1994; 76: 977-87.
-
(1994)
Cell
, vol.76
, pp. 977-987
-
-
Heusel, J.W.1
Wesselschmidt, R.L.2
Shresta, S.3
Russell, J.H.4
Ley, T.J.5
-
135
-
-
0030014911
-
Granzyme A is critical for recovery from infection with the natural cytopathic viral pathogen, ectromelia
-
Mullbacher A, Ebnet K, Blanden RV, et al. Granzyme A is critical for recovery from infection with the natural cytopathic viral pathogen, ectromelia. Proc Natl Acad Sci USA 1996; 93: 5783-7.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5783-5787
-
-
Mullbacher, A.1
Ebnet, K.2
Blanden, R.V.3
-
136
-
-
0033598718
-
Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
-
Mullbacher A, Waring P, Tha Hla R, et al. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc Natl Acad Sci USA 1999; 96: 13950-5.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13950-13955
-
-
Mullbacher, A.1
Waring, P.2
Tha Hla, R.3
-
137
-
-
0034880940
-
Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection
-
Balkow S, Kersten A, Tran TT, et al. Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection. J Virol 2001; 75: 8781-91.
-
(2001)
J Virol
, vol.75
, pp. 8781-8791
-
-
Balkow, S.1
Kersten, A.2
Tran, T.T.3
-
138
-
-
0034033438
-
Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection
-
Riera L, Gariglio M, Valente G, et al. Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection. Eur J Immunol 2000; 30: 1350-5.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1350-1355
-
-
Riera, L.1
Gariglio, M.2
Valente, G.3
-
139
-
-
23844461112
-
Functional analysis of granzyme M and its role in immunity to infection
-
Pao LI, Sumaria N, Kelly JM, et al. Functional analysis of granzyme M and its role in immunity to infection. J Immunol 2005; 175: 3235-43.
-
(2005)
J Immunol
, vol.175
, pp. 3235-3243
-
-
Pao, L.I.1
Sumaria, N.2
Kelly, J.M.3
-
140
-
-
0029847228
-
Long-range disruption of gene expression by a selectable marker cassette
-
Pham CT, MacIvor DM, Hug BA, Heusel JW, Ley TJ. Long-range disruption of gene expression by a selectable marker cassette. Proc Natl Acad Sci USA 1996; 93: 13090-5.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13090-13095
-
-
Pham, C.T.1
MacIvor, D.M.2
Hug, B.A.3
Heusel, J.W.4
Ley, T.J.5
-
141
-
-
13544266566
-
Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions
-
Revell PA, Grossman WJ, Thomas DA, et al. Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions. J Immunol 2005; 174: 2124-31.
-
(2005)
J Immunol
, vol.174
, pp. 2124-2131
-
-
Revell, P.A.1
Grossman, W.J.2
Thomas, D.A.3
-
142
-
-
0034488761
-
Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue
-
Estebanez-Perpina E, Fuentes-Prior P, Belorgey D, et al. Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue. Biol Chem 2000; 381: 1203-14.
-
(2000)
Biol Chem
, vol.381
, pp. 1203-1214
-
-
Estebanez-Perpina, E.1
Fuentes-Prior, P.2
Belorgey, D.3
-
143
-
-
0043047404
-
Transgenic mice that possess a disrupted mast cell protease 5 (mMCP-5) gene cannot store carboxypeptidase A in their granules
-
Stevens RL, Qui D, McNeill HP, et al. Transgenic mice that possess a disrupted mast cell protease 5 (mMCP-5) gene cannot store carboxypeptidase A in their granules. FASEB J 1996; 10: 1307.
-
(1996)
FASEB J
, vol.10
, pp. 1307
-
-
Stevens, R.L.1
Qui, D.2
McNeill, H.P.3
-
144
-
-
0344253682
-
Mast cell cathepsins C and S control levels of carboxypeptidase A and the chymase, mouse mast cell protease 5
-
Henningsson F, Wolters P, Chapman HA, Caughey GH, Pejler G. Mast cell cathepsins C and S control levels of carboxypeptidase A and the chymase, mouse mast cell protease 5. Biol Chem 2003; 384: 1527-31.
-
(2003)
Biol Chem
, vol.384
, pp. 1527-1531
-
-
Henningsson, F.1
Wolters, P.2
Chapman, H.A.3
Caughey, G.H.4
Pejler, G.5
|