New developments in the genetics and activation of mast cell proteases

Molecular Immunology

Volumn 38, Issue 16-18, 2002, Pages 1353-1357

  Caughey, George H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chymase; Dipeptidyl peptidase I; Mast cell; Tryptase

Indexed keywords

CHYMASE; DIPEPTIDYL PEPTIDASE I; ENZYME; ISOENZYME; TRYPTASE; CATHEPSIN; CATHEPSIN G; GRANZYME; GZMB PROTEIN, HUMAN; GZMB PROTEIN, MOUSE; MCPT6 PROTEIN, MOUSE; SERINE PROTEINASE; TPSAB1 PROTEIN, MOUSE;

ALLELE; BIOCHEMISTRY; CLASSIFICATION; CONFERENCE PAPER; ENZYME ACTIVATION; ENZYME RELEASE; GENE CLUSTER; GENE LOCUS; GENETIC VARIABILITY; IMMUNOGENETICS; KNOCKOUT GENE; MAST CELL; MOUSE STRAIN; MULTIGENE FAMILY; NULL ALLELE; PHYLOGENY; POPULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; ENZYMOLOGY; GENETICS; HUMAN; HUMAN CHROMOSOME; METABOLISM; MOUSE; PHYSIOLOGY; REVIEW;

MAMMALIA;

ANIMALS; CATHEPSINS; CHROMOSOMES, HUMAN; CHYMASES; DIPEPTIDYL PEPTIDASE I; GRANZYMES; HUMANS; MAST CELLS; MICE; MULTIGENE FAMILY; PHYLOGENY; SERINE ENDOPEPTIDASES; TRYPTASES;

EID: 0036034837     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(02)00087-1     Document Type: Conference Paper

References (29)

1. Caughey, G.H., 1995. Mast cell chymases and tryptases: phylogeny, family relations and biogenesis. In: Caughey, G.H. (Ed.), Mast Cell Proteases in Immunology and Biology. Marcel Dekker, New York, pp. 305-329.
2. Caughey G.H., Lazarus S.C., Viro N.F., Gold W.M., Nadel J.A. Tryptase and chymase: comparison of extraction and release in two dog mastocytoma lines. Immunology. 63:1988;339-344.
3. Caughey G.H., Zerweck E.H., Vanderslice P. Structure, chromosomal assignment and deduced amino acid sequence of a human gene for mast cell chymase. J. Biol. Chem. 266:1991;12956-12963.
4. Caughey G.H., Schaumberg T.H., Zerweck E.H., Butterfield J.H., Hanson R.D., Silverman G.A., Ley T.J. The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression. Genomics. 15:1993;614-620.
5. Caughey G.H., Blount J.L., Koerber K.L., Kitamura M., Fang K.C. Cloning and expression of the dog mast cell α-chymase gene. J. Immunol. 159:1997;4367-4375.
6. Caughey G.H., Raymond W.W., Blount J.L., Hau L.W.T., Pallaoro M., Wolters P.J., Verghese G.M. Characterization of human γ-tryptases, novel members of the chromosome 16p mast cell tryptase and prostasin gene families. J. Immunol. 164:2000a;6566-6575.
7. Caughey G.H., Raymond W.W., Wolters P.J. Angiotensin II generation by mast cell α- and β-chymases. Biochim. Biophys. Acta. 1480:2000b;245-257.
8. Chandrasekharan U.M., Sanker S., Glynias M.J., Karnik S.S., Husain A. Angiotensin II-forming activity in a reconstructed ancestral chymase. Science. 271:1996;502-505.
9. Daniels R.J., Peden J.F., Lloyd C., Horsley S.W., Clark K., Tufarelli C., Kearney L., Buckle V.J., Doggett N.A., Flint J., Higgs D.R. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. Hum. Mol. Genet. 10:2001;339-352.
10. Dikov M.M., Springman E.B., Yeola S., Serafin W.E. Processing of procarboxypeptidase A and other zymogens in murine mast cells. J. Biol. Chem. 269:1994;25897-25904.
11. Gurish M.F., Nadeau J.H., Johnson K.R., McNeil H.P., Grattan K.M., Austen K.F., Stevens R.L. A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14. J. Biol. Chem. 268:1993;11372-11379.
12. Huang R., Hellman L. Genes for mast cell serine proteases and their molecular evolution. Immunogenetics. 40:1994;397-414.
13. Irani A.A., Schechter N.M., Craig S.S., DeBlois G., Schwartz L.B. Two types of human mast cells that have distinct neutral protease compositions. Proc. Natl. Acad. Sci. U.S.A. 83:1986;4464-4468.
14. Lutzelschwab C., Pejler G., Aveskogh M., Hellman L. Secretory granule proteases in rat mast cells. Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations. J. Exp. Med. 185:1997;13-29.
15. McEuen A.R., Ashworth D.M., Walls A.F. The conversion of recombinant human mast cell prochymase to enzymatically active chymase by dipeptidyl peptidase I is inhibited by heparin and histamine. Eur. J. Biochem. 253:1998;300-308.
16. Murakami M., Karnik S.S., Husain A. Human prochymase activation. A novel role for heparin in zymogen processing. J. Biol. Chem. 270:1995;2218-2223.
17. Pallaoro M., Fejzo M.S., Shayesteh L., Blount J.L., Caughey G.H. Characterization of genes encoding known and novel human mast cell tryptases on chromosome 16p13.3. J. Biol. Chem. 274:1999;3355-3362.
18. Pemberton A.D., McAleese S.M., Huntley J.F., Collie D.D., Scudamore C.L., McEuen A.R., Walls A.F., Miller H.R. cDNA sequence of two sheep mast cell tryptases and the differential expression of tryptase and sheep mast cell proteinase 1 in lung, dermis and gastrointestinal tract. Clin. Exp. Allergy. 30:2000;818-832.
19. Polanowska J., Krokoszynska I., Czapinska H., Watorek W., Dadlez M., Otlewski J. Specificity of human cathepsin G. Biochim. Biophys. Acta. 1386:1998;189-198.
20. Sakai K., Ren S., Schwartz L.B. A novel heparin-dependent processing pathway for human tryptase: autocatalysis followed by activation with dipeptidyl peptidase I. J. Clin. Invest. 97:1996;988-995.
21. Schechter N.M., Irani A.M., Sprows J.L., Abernethy J., Wintroub B., Schwartz L.B. Identification of a cathepsin G-like proteinase in the MCTC-type of human mast cell. J. Immunol. 145:1990;2652-2661.
22. Shiota N., Fukamizu A., Okunishi H., Takai S., Murakami K., Miyazaki M. Cloning of the gene and cDNA for hamster chymase 2, and expression of chymase 1, chymase 2 and angiotensin-converting enzyme in the terminal stage of cardiomyopathic hearts. Biochem. J. 333:1998;417-424.
23. Stevens R.L., Friend D.S., McNeil H.P., Schiller V., Ghildyal N., Austen K.F. Strain- and tissue-specific expression of mouse mast cell secretory granule proteases. Proc. Natl. Acad. Sci. U.S.A. 91:1994;128-132.
24. Vanderslice P., Ballinger S.M., Tam E.K., Goldstein S.M., Craik C.S., Caughey G.H. Human mast cell tryptase: multiple cDNAs and genes reveal a multi-gene serine protease family. Proc. Natl. Acad. Sci. U.S.A. 87:1990;3811-3815.
25. Weidner N., Austen K.F. Heterogeneity of mast cells at multiple body sites - fluorescent determination of avidin binding and immunofluorescent determination of chymase, tryptase and carboxypeptidase content. Pathol. Res. Pract. 189:1993;156-162.
26. Wolters P.J., Raymond W.W., Blount J.L., Caughey G.H. Regulated expression, processing, and secretion of dog mast cell dipeptidyl peptidase I. J. Biol. Chem. 273:1998;15514-15520.
27. Wolters P.J., Laig-Webster M., Caughey G.H. Dipeptidyl peptidase I cleaves matrix-associated proteins and is expressed mainly by mast cells in normal dog airways. Am. J. Respir. Cell Mol. Biol. 22:2000;183-190.
28. Wolters P.J., Pham C.T., Muilenburg D.J., Ley T.J., Caughey G.H. Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice. J. Biol. Chem. 276:2001;18551-18556.
29. Wong G.W., Tang Y., Feyfant E., Sali A., Li L., Li Y., Huang C., Friend D.S., Krilis S.A., Stevens R.L. Identification of a new member of the tryptase family of mouse and human mast cell proteases which possesses a novel COOH-terminal hydrophobic extension. J. Biol. Chem. 274:1999;30784-30793.