Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue

Biological Chemistry

Volumn 381, Issue 12, 2000, Pages 1203-1214

  Estebanez Perpina E ^a   Fuentes Prior, P ^a   Belorgey, D ^a   Braun, M ^a   Kiefersauer, R ^a   Maskos, K ^a   Huber, R ^a   Rubin, H ^a   Bode, W ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Caspases; Crystal structure; Granzyme B; Serine proteinase; Specificity

Indexed keywords

AMINO ACID; ARGININE; ASPARTIC ACID; CALCIUM; CASPASE; CASPASE 3; CATHEPSIN G; CELL CYCLE PROTEIN; CHYMASE; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYSTEINE PROTEINASE; CYTOKINE; DIPEPTIDE; DIPEPTIDYL PEPTIDASE I; ENZYME INHIBITOR; GLUTAMIC ACID; GLYCINE; GRANZYME B; GUANIDINE; HEXAPEPTIDE; ISOLEUCINE; PEPTIDE DERIVATIVE; PERFORIN; PROTEINASE; SERINE; SERINE PROTEINASE; THREONINE; TRYPSIN; UNINDEXED DRUG;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; BACULOVIRUS; BINDING SITE; CELL ACTIVATION; CELL GRANULE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CYTOPLASM; CYTOTOXIC T LYMPHOCYTE; DIFFRACTION; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; RESIDUE ANALYSIS; RHEUMATOID ARTHRITIS; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; TARGET CELL DESTRUCTION;

AMINO ACID SEQUENCE; ASPARTIC ACID; CASPASE 3; CASPASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; GRANZYMES; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY;

STAPHYLOCOCCUS PHAGE 3A; UNIDENTIFIED BACULOVIRUS;

EID: 0034488761     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2000.148     Document Type: Article

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