메뉴 건너뛰기




Volumn 26, Issue 8, 2006, Pages 1712-1720

Transforming growth factor-βs and vascular disorders

Author keywords

Atherosclerosis; BMP; Hereditary hemorrhagic telangiectasia; Pulmonary hypertension; Restenosis; Signaling; TGF ; Vascular cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; NEUTRALIZING ANTIBODY; NOGGIN; OSTEOGENIC PROTEIN 1; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1;

EID: 33746829275     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000225287.20034.2c     Document Type: Short Survey
Times cited : (247)

References (99)
  • 2
    • 0035100974 scopus 로고    scopus 로고
    • Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: Noggin, chordin and DAN
    • Reddi AH. Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: noggin, chordin and DAN. Arthritis Res. 2001;3:1-5.
    • (2001) Arthritis Res , vol.3 , pp. 1-5
    • Reddi, A.H.1
  • 3
    • 0037085287 scopus 로고    scopus 로고
    • The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways
    • Nohe A, Hassel S, Ehrlich M, Neubauer F, Sebald W, Henis YI, Knaus P. The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways. J Biol Chem. 2002;277:5330-5338.
    • (2002) J Biol Chem , vol.277 , pp. 5330-5338
    • Nohe, A.1    Hassel, S.2    Ehrlich, M.3    Neubauer, F.4    Sebald, W.5    Henis, Y.I.6    Knaus, P.7
  • 4
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-β-Smad signaling
    • ten Dijke P, Hill CS. New insights into TGF-β-Smad signaling. Trends Biochem Sci. 2004;29:265-273.
    • (2004) Trends Biochem Sci , vol.29 , pp. 265-273
    • Ten Dijke, P.1    Hill, C.S.2
  • 5
    • 0035918274 scopus 로고    scopus 로고
    • Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
    • Ebisawa T, Fukuchi M, Murakami G, Ghiba T, Tanaka K, Imamura T, Miyazono K. Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J Biol Chem. 2001;276:12477-12480.
    • (2001) J Biol Chem , vol.276 , pp. 12477-12480
    • Ebisawa, T.1    Fukuchi, M.2    Murakami, G.3    Ghiba, T.4    Tanaka, K.5    Imamura, T.6    Miyazono, K.7
  • 6
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
    • Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P. Balancing the activation state of the endothelium via two distinct TGF-β type I receptors. EMBO J. 2002;21:1743-1753.
    • (2002) EMBO J , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    Ten Dijke, P.6
  • 7
    • 0036888627 scopus 로고    scopus 로고
    • Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells
    • Ota T, Fujii M, Sugizaki T, Ishii M, Miyazawa K, Aburatani H, Miyazono K. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells. J Cell Physiol. 2002;193:299-318.
    • (2002) J Cell Physiol , vol.193 , pp. 299-318
    • Ota, T.1    Fujii, M.2    Sugizaki, T.3    Ishii, M.4    Miyazawa, K.5    Aburatani, H.6    Miyazono, K.7
  • 8
    • 0037159280 scopus 로고    scopus 로고
    • Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells
    • Valdimarsdottir G, Goumans MJ, Rosendahl A, Brugman M, Itoh S, Lebrin F, Sideras P, ten Dijke P. Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells. Circulation. 2002;106:2263-2270.
    • (2002) Circulation , vol.106 , pp. 2263-2270
    • Valdimarsdottir, G.1    Goumans, M.J.2    Rosendahl, A.3    Brugman, M.4    Itoh, S.5    Lebrin, F.6    Sideras, P.7    Ten Dijke, P.8
  • 11
    • 0037047426 scopus 로고    scopus 로고
    • Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-β receptors II and I
    • Guerrero-Esteo M, Sanchez-Elsner T, Letamendia A, Bernabeu C. Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-β receptors II and I. J Biol Chem. 2002;277:29197-29209.
    • (2002) J Biol Chem , vol.277 , pp. 29197-29209
    • Guerrero-Esteo, M.1    Sanchez-Elsner, T.2    Letamendia, A.3    Bernabeu, C.4
  • 12
    • 0942298137 scopus 로고    scopus 로고
    • Effects of TGF-β2 on immune response-related gene expression profiles in the human corneal endothelium
    • Yamagami S, Yokoo S, Mimura T, Amino S. Effects of TGF-β2 on immune response-related gene expression profiles in the human corneal endothelium. Invest Ophthalmol Vis Sci. 2004;45:515-521.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 515-521
    • Yamagami, S.1    Yokoo, S.2    Mimura, T.3    Amino, S.4
  • 13
    • 0029989979 scopus 로고    scopus 로고
    • Vascular smooth muscle cells express multiple type I receptors for TGF-β, activin and bone morphogenetic proteins
    • Agrotis A, Samuel M, Prapas G, Bobik A. Vascular smooth muscle cells express multiple type I receptors for TGF-β, activin and bone morphogenetic proteins. Biochem Biophys Res Commun. 1996;219:613-618.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 613-618
    • Agrotis, A.1    Samuel, M.2    Prapas, G.3    Bobik, A.4
  • 14
    • 27744494454 scopus 로고    scopus 로고
    • TGF-β-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent
    • Seay U, Sedding D, Krick S, Hecker M, Seegar W, Ieickelberg O. TGF-β-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent. J Pharmacol Exp Ther. 2005;315:1005-1012.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 1005-1012
    • Seay, U.1    Sedding, D.2    Krick, S.3    Hecker, M.4    Seegar, W.5    Ieickelberg, O.6
  • 15
    • 1342283050 scopus 로고    scopus 로고
    • Concerted effect of transforming growth factor-β, cyclin inhibitor p21 and c-myc on smooth muscle cell proliferation
    • Khanna A. Concerted effect of transforming growth factor-β, cyclin inhibitor p21 and c-myc on smooth muscle cell proliferation. Am J Physiol. 2004;286:H1133-H1140.
    • (2004) Am J Physiol , vol.286
    • Khanna, A.1
  • 17
    • 20144375510 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor type-I gene expression and induced migration in TGF-β1-stimulated smooth muscle cells is pp60(c-Src)/MEK- dependent
    • Samarakoon R, Higgins CE, Higgins SP, Kutz SM, Higgins PJ. Plasminogen activator inhibitor type-I gene expression and induced migration in TGF-β1-stimulated smooth muscle cells is pp60(c-Src)/MEK-dependent. J Cell Physiol. 2005;204:236-246.
    • (2005) J Cell Physiol , vol.204 , pp. 236-246
    • Samarakoon, R.1    Higgins, C.E.2    Higgins, S.P.3    Kutz, S.M.4    Higgins, P.J.5
  • 18
    • 21844437967 scopus 로고    scopus 로고
    • Disabled-2 (Dab2) mediates transforming growth factor β (TGFβ)-stimulated fibronectin synthesis through TGFβ-activated kinase! and activation of the JNK pathway
    • Hocevar BA, Prunier C, Howe PH. Disabled-2 (Dab2) mediates transforming growth factor β (TGFβ)-stimulated fibronectin synthesis through TGFβ-activated kinase ! and activation of the JNK pathway. J Biol Chem. 2005;280:25920-25927.
    • (2005) J Biol Chem , vol.280 , pp. 25920-25927
    • Hocevar, B.A.1    Prunier, C.2    Howe, P.H.3
  • 19
    • 0033399104 scopus 로고    scopus 로고
    • Bidirectional regulation of macrophage function by TGF-β
    • Ashcroft GS. Bidirectional regulation of macrophage function by TGF-β. Microbes Infect. 1999;1:1275-1282.
    • (1999) Microbes Infect , vol.1 , pp. 1275-1282
    • Ashcroft, G.S.1
  • 20
    • 0027212738 scopus 로고
    • Transforming growth factor β enhances integrin expression and type IV collagenase secretion in human monocytes
    • Wahl SM, Allen JB, Weeks BS, Wong HL, Klotman PE. Transforming growth factor β enhances integrin expression and type IV collagenase secretion in human monocytes. Proc Natl Acad Sci U S A. 1993;90:4577-4581.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 4577-4581
    • Wahl, S.M.1    Allen, J.B.2    Weeks, B.S.3    Wong, H.L.4    Klotman, P.E.5
  • 22
    • 0034161681 scopus 로고    scopus 로고
    • TGF-β1 reciprocally controls chemotaxis of human peripheral blood monocyte-derived dendritic cells via chemokine receptors
    • Sato K, Kawasaki H, Nagayama H, Enomoto M, Morimoto C, Tadokoro K, Juji T, Takahashi TA. TGF-β1 reciprocally controls chemotaxis of human peripheral blood monocyte-derived dendritic cells via chemokine receptors. J Immunol. 2000;164:2285-2295.
    • (2000) J Immunol , vol.164 , pp. 2285-2295
    • Sato, K.1    Kawasaki, H.2    Nagayama, H.3    Enomoto, M.4    Morimoto, C.5    Tadokoro, K.6    Juji, T.7    Takahashi, T.A.8
  • 23
    • 0025429275 scopus 로고
    • Transforming growth factor β induces the production of interleukin 6 by human peripheral blood mononuclear cells
    • Turner M, Chantry D, Feldmann M. Transforming growth factor β induces the production of interleukin 6 by human peripheral blood mononuclear cells. Cytokine. 1990;2:211-216.
    • (1990) Cytokine , vol.2 , pp. 211-216
    • Turner, M.1    Chantry, D.2    Feldmann, M.3
  • 24
    • 0034986470 scopus 로고    scopus 로고
    • TGF-β increases cholesterol efflux and ABC-1 expression in macrophage-derived foam cells: Opposing the effects of IFN-γ
    • Panousis CG, Evans G, Zuckerman SH. TGF-β increases cholesterol efflux and ABC-1 expression in macrophage-derived foam cells: opposing the effects of IFN-γ. J Lipid Res. 2001;42:856-863.
    • (2001) J Lipid Res , vol.42 , pp. 856-863
    • Panousis, C.G.1    Evans, G.2    Zuckerman, S.H.3
  • 25
    • 14844367135 scopus 로고    scopus 로고
    • A critical role for the Ap1-binding sites in the transforming growth factor-mediated inhibition of lipoprotein lipase gene expression in macrophages
    • Irvine SA, Foka P, Rogers SA, Mead JR, Ramji DP. A critical role for the Ap1-binding sites in the transforming growth factor-mediated inhibition of lipoprotein lipase gene expression in macrophages. Nucleic Acids Res. 2005;33:1423-1434.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1423-1434
    • Irvine, S.A.1    Foka, P.2    Rogers, S.A.3    Mead, J.R.4    Ramji, D.P.5
  • 27
    • 20744453869 scopus 로고    scopus 로고
    • TGF-β1 enhances degradation of IFN-γ-induced iNOS protein via proteasomes in RAW264.7 cells
    • Mitani T, Terashima M, Yoshimura H, Nariai Y, Tanigawa Y. TGF-β1 enhances degradation of IFN-γ-induced iNOS protein via proteasomes in RAW264.7 cells. Nitric Oxide. 2005;13:78-87.
    • (2005) Nitric Oxide , vol.13 , pp. 78-87
    • Mitani, T.1    Terashima, M.2    Yoshimura, H.3    Nariai, Y.4    Tanigawa, Y.5
  • 28
    • 0042888950 scopus 로고    scopus 로고
    • TGFβ inhibits LPS-induced chemokine mRNA stabilization
    • Dai Y, Datta S, Novotny M, Hamilton TA. TGFβ inhibits LPS-induced chemokine mRNA stabilization. Blood. 2003;102:1178-1185.
    • (2003) Blood , vol.102 , pp. 1178-1185
    • Dai, Y.1    Datta, S.2    Novotny, M.3    Hamilton, T.A.4
  • 29
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • Gorelik L, Flavell RA. Abrogation of TGFβ signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity. 2000;12:171-181.
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 30
    • 0034679703 scopus 로고    scopus 로고
    • Blockade of transforming growth factor β/smad signaling in T cells by overexpression of smad7 enhances antigen-induced airway inflammation and airway reactivity
    • Nakao A, Miike S, Hatano M, Okumura K, Tokuhisa T, Ra C, Iwamoto I. Blockade of transforming growth factor β/smad signaling in T cells by overexpression of smad7 enhances antigen-induced airway inflammation and airway reactivity. J Exp Med. 2000;192:151-158.
    • (2000) J Exp Med , vol.192 , pp. 151-158
    • Nakao, A.1    Miike, S.2    Hatano, M.3    Okumura, K.4    Tokuhisa, T.5    Ra, C.6    Iwamoto, I.7
  • 31
    • 0035879091 scopus 로고    scopus 로고
    • Regulation of TGF-β response during T cell activation is modulated by IL-10
    • Cottrez F, Groux H. Regulation of TGF-β response during T cell activation is modulated by IL-10. J Immunol. 2001;167:773-778.
    • (2001) J Immunol , vol.167 , pp. 773-778
    • Cottrez, F.1    Groux, H.2
  • 32
    • 0036885067 scopus 로고    scopus 로고
    • The lineage decisions of helper T cells
    • Murphy KM, Reiner SL. The lineage decisions of helper T cells. Nat Rev Immunol. 2002;2:933-944.
    • (2002) Nat Rev Immunol , vol.2 , pp. 933-944
    • Murphy, K.M.1    Reiner, S.L.2
  • 33
    • 0042530470 scopus 로고    scopus 로고
    • Transcriptional regulation of tristetraprolin by transforming growth factor-β in human T cells
    • Ogawa K, Chen F, Kim YJ, Chen Y. Transcriptional regulation of tristetraprolin by transforming growth factor-β in human T cells. J Biol Chem. 2003;278:30373-30381.
    • (2003) J Biol Chem , vol.278 , pp. 30373-30381
    • Ogawa, K.1    Chen, F.2    Kim, Y.J.3    Chen, Y.4
  • 38
    • 6344283050 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase
    • Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassegue B, Griendling KK, Jo H. Bone morphogenetic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circ Res. 2004;95:773-779.
    • (2004) Circ Res , vol.95 , pp. 773-779
    • Sorescu, G.P.1    Song, H.2    Tressel, S.L.3    Hwang, J.4    Dikalov, S.5    Smith, D.A.6    Boyd, N.L.7    Platt, M.O.8    Lassegue, B.9    Griendling, K.K.10    Jo, H.11
  • 39
    • 0038044657 scopus 로고    scopus 로고
    • Bone morphogenetic protein4 mediates apoptosis of capillary endothelial cells during rat pupillary membrane regression
    • Kiyono M, Shibuya M. Bone morphogenetic protein4 mediates apoptosis of capillary endothelial cells during rat pupillary membrane regression. Mol Cell Biol. 2003;23:4627-4636.
    • (2003) Mol Cell Biol , vol.23 , pp. 4627-4636
    • Kiyono, M.1    Shibuya, M.2
  • 40
    • 0034074899 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro
    • Dorai H, Vukicevic S, Sampath TK. Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro. J Cell Physiol. 2000;184:37-45.
    • (2000) J Cell Physiol , vol.184 , pp. 37-45
    • Dorai, H.1    Vukicevic, S.2    Sampath, T.K.3
  • 42
    • 0033536016 scopus 로고    scopus 로고
    • Distinct patterns of transforming growth factor-β isoforms and receptor expression in human atherosclerotic lesions. Colocalisation implicates TGF-β in fibrofatty lesion development
    • Bobik A, Agrotis A, Kanellakis P, Dilley R, Krushinsky A, Smirnov V, Tararak E, Condron M, Kostolias G. Distinct patterns of transforming growth factor-β isoforms and receptor expression in human atherosclerotic lesions. Colocalisation implicates TGF-β in fibrofatty lesion development. Circulation. 1999;99:2883-2891.
    • (1999) Circulation , vol.99 , pp. 2883-2891
    • Bobik, A.1    Agrotis, A.2    Kanellakis, P.3    Dilley, R.4    Krushinsky, A.5    Smirnov, V.6    Tararak, E.7    Condron, M.8    Kostolias, G.9
  • 44
    • 0028859484 scopus 로고
    • Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β
    • McCaffrey TA, Consigli S, Du B, Falcone DJ, Sanborn TA, Spokojny AM, Bush HL Jr. Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β. J Clin Invest. 1995;96:2667-2675.
    • (1995) J Clin Invest , vol.96 , pp. 2667-2675
    • McCaffrey, T.A.1    Consigli, S.2    Du, B.3    Falcone, D.J.4    Sanborn, T.A.5    Spokojny, A.M.6    Bush Jr., H.L.7
  • 45
    • 3943049366 scopus 로고    scopus 로고
    • Smad expression in human atherosclerotic lesions: Evidence for impaired TGF-β/Smad signaling in smooth muscle cells of fibrofatty lesions
    • Kalinina N, Agrotis A, Antropova Y, Ilyinskaya O, Smirnov V, Tararak E, Bobik A. Smad expression in human atherosclerotic lesions: evidence for impaired TGF-β/Smad signaling in smooth muscle cells of fibrofatty lesions. Arterioscler Thromb Vasc Biol. 2004;24:1391-1396.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1391-1396
    • Kalinina, N.1    Agrotis, A.2    Antropova, Y.3    Ilyinskaya, O.4    Smirnov, V.5    Tararak, E.6    Bobik, A.7
  • 46
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression
    • Amento EP, Ehsani N, Palmer H, Libby P. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression. Arterioscler Thromb Vasc Biol. 1991;11:1223-1230.
    • (1991) Arterioscler Thromb Vasc Biol , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 50
    • 10644252898 scopus 로고    scopus 로고
    • Differential expression patterns of proinflammatory and antiinflammatory mediators during atherogenesis in mice
    • Veillard NR, Steffens S, Burger F, Pelli G, Mach F. Differential expression patterns of proinflammatory and antiinflammatory mediators during atherogenesis in mice. Arterioscler Thromb Vasc Biol. 2004;24:2339-2344.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2339-2344
    • Veillard, N.R.1    Steffens, S.2    Burger, F.3    Pelli, G.4    Mach, F.5
  • 53
    • 17144400393 scopus 로고    scopus 로고
    • TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med. 2005;201:1061-1067.
    • (2005) J Exp Med , vol.201 , pp. 1061-1067
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 56
    • 0037837819 scopus 로고    scopus 로고
    • Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor β1 in the regulation of vascular smooth muscle phenotype
    • King KE, Iyemere VP, Weissberg PL, Shanahan CM. Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor β1 in the regulation of vascular smooth muscle phenotype. J Biol Chem. 2003;278:11661-11669.
    • (2003) J Biol Chem , vol.278 , pp. 11661-11669
    • King, K.E.1    Iyemere, V.P.2    Weissberg, P.L.3    Shanahan, C.M.4
  • 57
    • 0037341318 scopus 로고    scopus 로고
    • Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification
    • Tyson KL, Reynolds JL, McNair R, Zhang Q, Weissberg PL, Shanahan CM. Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification. Arterioscler Thromb Vasc Biol. 2003;23:489-494.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 489-494
    • Tyson, K.L.1    Reynolds, J.L.2    McNair, R.3    Zhang, Q.4    Weissberg, P.L.5    Shanahan, C.M.6
  • 60
    • 0037835949 scopus 로고    scopus 로고
    • BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure
    • Davies MR, Lund R, Kruska KA. BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. J Am Soc Nephrol. 2003;14:1559-1567.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1559-1567
    • Davies, M.R.1    Lund, R.2    Kruska, K.A.3
  • 61
    • 0031456560 scopus 로고    scopus 로고
    • Inhibition of protein tyrosine kinases attenuates increases in expression of transforming growth factor-β isoforms and their receptors after arterial injury
    • Ward MR, Agrotis A, Kanellakis P, Dilley R, Jennings G, Bobik A. Inhibition of protein tyrosine kinases attenuates increases in expression of transforming growth factor-β isoforms and their receptors after arterial injury. Arterioscler Thromb Vasc Biol. 1997;17:2461-2470.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2461-2470
    • Ward, M.R.1    Agrotis, A.2    Kanellakis, P.3    Dilley, R.4    Jennings, G.5    Bobik, A.6
  • 62
    • 0022550086 scopus 로고
    • Type β transforming growth factor in human platelets: Release during platelet degranulation and action on vascular smooth muscle cells
    • Assoain RK, Sporn MB. Type β transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells. J Cell Biol. 1986;102:1217-1223.
    • (1986) J Cell Biol , vol.102 , pp. 1217-1223
    • Assoain, R.K.1    Sporn, M.B.2
  • 63
    • 0032720627 scopus 로고    scopus 로고
    • Transforming growth factor β1 enhances platelet aggregation through a non-transcriptional effect on the fibrinogen receptor
    • Hoying JB, Yin M, Diebold R, Ormsby I, Becker A, Doetschman T. Transforming growth factor β1 enhances platelet aggregation through a non-transcriptional effect on the fibrinogen receptor. J Biol Chem. 1999;274:31008-31013.
    • (1999) J Biol Chem , vol.274 , pp. 31008-31013
    • Hoying, J.B.1    Yin, M.2    Diebold, R.3    Ormsby, I.4    Becker, A.5    Doetschman, T.6
  • 64
    • 30744479182 scopus 로고    scopus 로고
    • TGF-β1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: A new mechanism for microvascular lesion during cerebral malaria
    • Wassmer SC, de Souza JB, Frere C, Candal FJ, Juhan-Vague I, Grau GE. TGF-β1 released from activated platelets can induce TNF-stimulated human brain endothelium apoptosis: a new mechanism for microvascular lesion during cerebral malaria. J Immunol. 2006;176:1180-1184.
    • (2006) J Immunol , vol.176 , pp. 1180-1184
    • Wassmer, S.C.1    De Souza, J.B.2    Frere, C.3    Candal, F.J.4    Juhan-Vague, I.5    Grau, G.E.6
  • 65
    • 0033586694 scopus 로고    scopus 로고
    • Vascular cell apoptosis: Cell type-specific modulation by transforming growth factor-β1 in endothelial cells versus smooth muscle cells
    • Pollman MJ, Naumovski L, Gibbons GH. Vascular cell apoptosis: cell type-specific modulation by transforming growth factor-β1 in endothelial cells versus smooth muscle cells. Circulation. 1999;99:2019-2026.
    • (1999) Circulation , vol.99 , pp. 2019-2026
    • Pollman, M.J.1    Naumovski, L.2    Gibbons, G.H.3
  • 69
    • 0036072237 scopus 로고    scopus 로고
    • Tranilast prevents activation of transforming growth factor system, leukocyte accumulation and neointimal growth in porcine coronary arteries after stenting
    • Ward MR, Agrotis A, Kanellakis P, Hall J, Jennings G, Bobik A. Tranilast prevents activation of transforming growth factor system, leukocyte accumulation and neointimal growth in porcine coronary arteries after stenting. Arterioscler Thromb Vasc Biol. 2002;22:940-948.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 940-948
    • Ward, M.R.1    Agrotis, A.2    Kanellakis, P.3    Hall, J.4    Jennings, G.5    Bobik, A.6
  • 70
    • 0025114866 scopus 로고
    • TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
    • Battegay EJ, Raines EW, Seifert RA, Bowen-Pope DF, Ross R. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell. 1990;63:515-524.
    • (1990) Cell , vol.63 , pp. 515-524
    • Battegay, E.J.1    Raines, E.W.2    Seifert, R.A.3    Bowen-Pope, D.F.4    Ross, R.5
  • 71
    • 30044435231 scopus 로고    scopus 로고
    • Proliferation of pulmonary interstitial fibroblasts is mediated by TGF-β induced release of extracellular FGF-2 and phosphorylation of p38MAPK and JNK
    • Khalil N, Xu YD, O'Connor R, Duronio V. Proliferation of pulmonary interstitial fibroblasts is mediated by TGF-β induced release of extracellular FGF-2 and phosphorylation of p38MAPK and JNK. J Biol Chem. 2005;280:43000-43009.
    • (2005) J Biol Chem , vol.280 , pp. 43000-43009
    • Khalil, N.1    Xu, Y.D.2    O'Connor, R.3    Duronio, V.4
  • 77
    • 0030047241 scopus 로고    scopus 로고
    • Clinical heterogeneity in hereditary haemorrhagic telangiectasia: Are pulmonary arteriovenous malformations more common in families linked to endoglin?
    • Berg J, Guttmacher A, Marchuk D, Porteous ME. Clinical heterogeneity in hereditary haemorrhagic telangiectasia: are pulmonary arteriovenous malformations more common in families linked to endoglin? J Med Genet. 1996;33:256-257.
    • (1996) J Med Genet , vol.33 , pp. 256-257
    • Berg, J.1    Guttmacher, A.2    Marchuk, D.3    Porteous, M.E.4
  • 78
    • 0034443720 scopus 로고    scopus 로고
    • Endoglin-deficient mice, a unique model to study heteritart hemorrhagic telangiectasia
    • Bourdeau A, Faughnan ME, Letarte M. Endoglin-deficient mice, a unique model to study heteritart hemorrhagic telangiectasia. Trends Cardiovasc Med. 2000;10:279-285.
    • (2000) Trends Cardiovasc Med , vol.10 , pp. 279-285
    • Bourdeau, A.1    Faughnan, M.E.2    Letarte, M.3
  • 79
    • 0033757655 scopus 로고    scopus 로고
    • Arteriovenous malformations in mice lacking activin receptor-like kinase-1
    • Urness LD, Sorensen LK, Li DY. Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000;26:328-331.
    • (2000) Nat Genet , vol.26 , pp. 328-331
    • Urness, L.D.1    Sorensen, L.K.2    Li, D.Y.3
  • 80
    • 0043164827 scopus 로고    scopus 로고
    • Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFβ coreceptor
    • Sorensen LK, Brooke BS, Li DY, Urness LD. Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFβ coreceptor. Dev Biol. 2003;261:235-250.
    • (2003) Dev Biol , vol.261 , pp. 235-250
    • Sorensen, L.K.1    Brooke, B.S.2    Li, D.Y.3    Urness, L.D.4
  • 81
    • 12344255297 scopus 로고    scopus 로고
    • Defective paracrine signaling by TGFβ in yolk sac vasculature of endoglin mutant mice: A paradigm for hereditary haemorrhagic telangiectasia
    • Carvalho RL, Jonker L, Goumans MJ, Larsson J, Bouman P, Karlsson S, ten Dijke P, Arthus HM, Mummery CL. Defective paracrine signaling by TGFβ in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development. 2004;131:6237-6247.
    • (2004) Development , vol.131 , pp. 6237-6247
    • Carvalho, R.L.1    Jonker, L.2    Goumans, M.J.3    Larsson, J.4    Bouman, P.5    Karlsson, S.6    Ten Dijke, P.7    Arthus, H.M.8    Mummery, C.L.9
  • 83
    • 24344461857 scopus 로고    scopus 로고
    • Reduced endothelial secretion and plasma levels of transforming growth factor-β1 in patients with hereditary hemorrhagic telangiectasia type 1
    • Letarte M, McDonald LM, Li C, Kathirkamathamby K, Vera S, Pece-Barbara N, Kumar S. Reduced endothelial secretion and plasma levels of transforming growth factor-β1 in patients with hereditary hemorrhagic telangiectasia type 1. Cardiovasc Res. 2005;68:155-164.
    • (2005) Cardiovasc Res , vol.68 , pp. 155-164
    • Letarte, M.1    McDonald, L.M.2    Li, C.3    Kathirkamathamby, K.4    Vera, S.5    Pece-Barbara, N.6    Kumar, S.7
  • 84
    • 16444373524 scopus 로고    scopus 로고
    • A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia
    • Toporsian M, Gros R, Kabir MG, Vera S, Govindaraju K, Eidelman DH, Husian M, Letarte M. A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia. Circ Res. 2005;96:684-692.
    • (2005) Circ Res , vol.96 , pp. 684-692
    • Toporsian, M.1    Gros, R.2    Kabir, M.G.3    Vera, S.4    Govindaraju, K.5    Eidelman, D.H.6    Husian, M.7    Letarte, M.8
  • 85
    • 0034970744 scopus 로고    scopus 로고
    • Potential role of modifier genes influencing transforming growth factor-β1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia
    • Bourdeau A, Faughnan ME, McDonald ML, Paterson AD, Wanless IR, Letarte M. Potential role of modifier genes influencing transforming growth factor-β1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia. Am J Pathol. 2001;158:2011-2020.
    • (2001) Am J Pathol , vol.158 , pp. 2011-2020
    • Bourdeau, A.1    Faughnan, M.E.2    McDonald, M.L.3    Paterson, A.D.4    Wanless, I.R.5    Letarte, M.6
  • 89
    • 8644256840 scopus 로고    scopus 로고
    • BMPR-II heterozygous mice have mild pulmonary hypertension and impaired pulmonary vascular remodeling response to prolonged hypoxia
    • Beppu H, Ichinose F, Kawai N, Jones RC, Yu PB, Zapol WM, Miyazono K, Li E, Blcoh KD. BMPR-II heterozygous mice have mild pulmonary hypertension and impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol. 2004;287:L1241-L1247.
    • (2004) Am J Physiol , vol.287
    • Beppu, H.1    Ichinose, F.2    Kawai, N.3    Jones, R.C.4    Yu, P.B.5    Zapol, W.M.6    Miyazono, K.7    Li, E.8    Blcoh, K.D.9
  • 91
    • 0022506203 scopus 로고
    • The case for treatment of selected patients with primary pulmonary hypertension
    • Reeves JT, Groves BM, Turkevich D. The case for treatment of selected patients with primary pulmonary hypertension. Am Rev Respir Dis. 1986;134:342-346.
    • (1986) Am Rev Respir Dis , vol.134 , pp. 342-346
    • Reeves, J.T.1    Groves, B.M.2    Turkevich, D.3
  • 93
    • 0035859940 scopus 로고    scopus 로고
    • Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-β1 and bone morphogenetic proteins
    • Morrell NW, Yang X, Upton PD, Jourdan KB, Morgan N, Sheares KK, Trembath RC. Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-β1 and bone morphogenetic proteins. Circulation. 2001;104:790-795.
    • (2001) Circulation , vol.104 , pp. 790-795
    • Morrell, N.W.1    Yang, X.2    Upton, P.D.3    Jourdan, K.B.4    Morgan, N.5    Sheares, K.K.6    Trembath, R.C.7
  • 94
    • 0348013127 scopus 로고    scopus 로고
    • Functional interaction between BMPR-II and Tctex-1, a light chain of dynein, is isoforms-specific and disrupted by mutations underlying primary pulmonary hypertension
    • Machado RD, Rudarakanchana N, Atkinson C, Flanagan JA, Harrison R, Morrell NW, Trembath RC. Functional interaction between BMPR-II and Tctex-1, a light chain of dynein, is isoforms-specific and disrupted by mutations underlying primary pulmonary hypertension. Hum Mol Genet. 2003;12:3277-3286.
    • (2003) Hum Mol Genet , vol.12 , pp. 3277-3286
    • Machado, R.D.1    Rudarakanchana, N.2    Atkinson, C.3    Flanagan, J.A.4    Harrison, R.5    Morrell, N.W.6    Trembath, R.C.7
  • 95
    • 27644572195 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor type II C-terminus interacts with c-Src
    • Wong WK, Knowles JA, Morse JH. Bone morphogenetic protein receptor type II C-terminus interacts with c-Src. Am J Respir Cell Mol Biol. 2005;33:438-446.
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 438-446
    • Wong, W.K.1    Knowles, J.A.2    Morse, J.H.3
  • 98
    • 31444445231 scopus 로고    scopus 로고
    • The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signaling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells
    • Xin C, Ren S, Eberhardt W, Pfeilschifter J, Huwiler A. The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signaling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells. Br J Pharmacol. 2006;147:164-174.
    • (2006) Br J Pharmacol , vol.147 , pp. 164-174
    • Xin, C.1    Ren, S.2    Eberhardt, W.3    Pfeilschifter, J.4    Huwiler, A.5
  • 99
    • 31044448265 scopus 로고    scopus 로고
    • Characterization of SIS3, a novel specific inhibitor of smad3 and its effects on transforming growth factor-β1-induced extracellular matrix expression
    • Jinnin M, Ihn H, Tamaki K. Characterization of SIS3, a novel specific inhibitor of smad3 and its effects on transforming growth factor-β1-induced extracellular matrix expression. Mol Pharmacol. 2006;69:597-607.
    • (2006) Mol Pharmacol , vol.69 , pp. 597-607
    • Jinnin, M.1    Ihn, H.2    Tamaki, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.