Transforming growth factor β1 enhances platelet aggregation through a non-transcriptional effect on the fibrinogen receptor

Journal of Biological Chemistry

Volumn 274, Issue 43, 1999, Pages 31008-31013

  Hoying, James B ^a,c   Yin, Moying ^a   Diebold, Ronald ^a,d   Ormsby, Ilona ^a   Becker, Ann ^b   Doetschman, Thomas ^a,e  

^a UNIVERSITY OF CINCINNATI   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c University of Arizona   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 O METHYLPHORBOL 13 ACETATE 12 MYRISTATE; FIBRINOGEN; FIBRINOGEN RECEPTOR; INTEGRIN; PADGEM PROTEIN; PROTEIN KINASE C; THROMBOXANE A2; TRANSFORMING GROWTH FACTOR BETA1;

ADOLESCENT; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BLEEDING DISORDER; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; THROMBOCYTHEMIA;

ADENOSINE DIPHOSPHATE; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLEEDING TIME; BLOOD PLATELETS; COLLAGEN; CROSSES, GENETIC; FATTY ACIDS, UNSATURATED; FIBRINOGEN; MEGAKARYOCYTES; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; MICE, SCID; PLATELET AGGREGATION; PLATELET COUNT; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SIGNAL TRANSDUCTION; THROMBIN; THROMBOCYTOPENIA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032720627     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.43.31008     Document Type: Article

References (42)

1. Vlodavsky, I., Eldor, A., HyAm, E., Atzom, R., and Fuks, Z. (1982) Thromb. Res. 28, 179-191
2. Turitto, V. T., Weiss, H. J., Zimmerman, T. S., and Sussman, I. I. (1985) Blood 65, 823-831
3. Rink, T. J., Smith, S. W., and Tsien, R. Y. (1982) FEBS Lett. 148, 21-26
4. Assoian, R. K., Komoriya, A., Meyers, C. A., Miller, D. M., and Sporn, M. B. (1983) J. Biol. Chem. 258, 7155-7160
5. Grainger, D. J., Wakefield, L., Bethell, H. W., Farndale, R. W., and Metcalfe, J. C. (1995) Nat. Med. 1, 932-937
6. Gamble, J. R., and Vadas, M. A. (1988) Science 242, 97-99
7. Heimark, R. L., Twardzik, D. R., and Schwartz, S. M. (1986) Science 233, 1078-1080
8. Bjorkerud, S. (1991) Arterioscler. Thromb. 11, 892-902
9. Shi, Y., O'Brien, J. E. J., Fard, A., and Zalewski, A. (1996) Arterioscler. Thromb. Vasc. Biol. 16, 1298-1305
10. Nabel, E. G., Shum, L., Pompili, V. J., Yang, Z. Y., San, H., Shu, H. B., Liptay, S., Gold, L., Gordon, D., and Derynck, R. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 10759-10763
11. Lawrence, R., Hartmann, D. J., and Sonenshein, G. E. (1994) J. Biol. Chem. 269, 9603-9609
12. Heldin, C. H., Miyazono, K., and ten Dijke, P. (1997) Nature 390, 465-471
13. Kretzschmar, M., and Massague, J. (1998) Curr. Opin. Genet. Dev. 8, 103-111
14. Zawel, L., Dai, J. L., Buckhaults, P., Zhou, S., Kinzler, K. W., Vogelstein, B., and Kern, S. E. (1998) Mol. Cell 1, 611-617
15. Shi, Y., Wang, Y. F., Jayaraman, L., Yang, H., Massague, J., and Pavletich, N. P. (1998) Cell 94, 585-594
16. Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S., and Gauthier, J. M. (1998) EMBO J. 17, 3091-3100
17. Vindevoghel, L., Kon, A., Lechleider, R. J., Uitto, J., Roberts, A. B., and Mauviel, A. (1998) J. Biol. Chem. 273, 13053-13057
18. Kawabata, M., Imamura, T., Miyazono, K., Engel, M. E., and Moses, H. L. (1995) J. Biol. Chem. 270, 29628-29631
19. Sandhu, C., Garbe, J., Bhattacharya, N., Daksis, J., Pan, C. H., Yaswen, P., Koh, J., Slingerland, J. M., and Stampfer, M. R. (1997) Mol. Cell. Biol. 17, 2458-2467
20. Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., Yin, M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., Annunziata, N., and Doetschman, T. (1992) Nature 359, 693-699
21. Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M., and Karlsson, S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 770-774
22. Boivin, G. P., O'Toole, B. A., Ormsby, I. E., Diebold, R. J., Eis, M. J., Doetschman, T. C., and Kier, A. B. (1995) Am. J. Pathol. 146, 276-288
23. Diebold, R. J., Eis, M. J., Yin, M., Ormsby, I., Boivin, G. P., Darrow, B. J., Saffitz, J. E., and Doetschman, T. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 12215-12219
24. Oyekan, A. O., and Onabanjo, A. O. (1991) Haemostasis 21, 360-369
25. Warkentin, T. E., Fowling, M. J., and Hardisty, R. M. (1990) Br. J. Haematol. 76, 387-394
26. Shattil, S. J., Hoxie, J. A., Cunningham, M., and Brass, L. F. (1985) J. Biol. Chem. 260, 11107-11114
27. Massague, J., and Like, B. (1985) J. Biol. Chem. 260, 2636-2645
28. Dorn, G. W., and DeJesus, A. (1991) Am. J. Physiol. 260, H327-H334
29. Ishibashi, T., Miller, S. L., and Burstein, S. A. (1987) Blood 69, 1737-1741
30. Kuter, D. J., Gminski, D. M., and Rosenberg, R. D. (1992) Blood 79, 619-626
31. Zauli, G., Vitale, L., Brunelli, M. A., and Bagnara, G. P. (1992) Exp. Hematol. 20, 850-854
32. Carlino, J. A., Higley, H. R., Creson, J. R., Avis, P. D., Ogawa, Y., and Ellingsworth, L. R. (1992) Exp. Hematol. 20, 943-950
33. Tobelem, G. (1989) Baillieres Clin. Haematol. 2, 719-728
34. Wehmeier, A., Sudhoff, T., and Meierkord, F. (1997) Semin. Thromb. Hemost. 23, 391-402
35. Johnson, E. N., Brass, L. F., and Funk, C. D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3100-3105
36. Kovacsovics, T. J., Bachelot, C., Toker, A., Vlahos, C. J., Duckworth, B., Cantley, L. C., and Hartwig, J. H. (1995) J. Biol. Chem. 270, 11358-11366
37. Zhang, J., Shattil, S. J., Cunningham, M. C., and Rittenhouse, S. E. (1996) J. Biol. Chem. 271, 6265-6272
38. Wrana, J. L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. F., and Massague, J. (1992) Cell 71, 1003-1014
39. Wang, T., Danielson, P. D., Li, B. Y., Shah, P. C., Kim, S. D., and Donahoe, P. K. (1996) Science 271, 1120-1122
40. Finder, J., Stark, W. W. J., Nakayama, D. K., Geller, D., Wasserloos, K., Pitt, B. R., and Davies, P. (1995) Am. J. Physiol. 268, L862-L867
41. Kropf, J., Schurek, J. O., Wollner, A., and Gressner, A. M. (1997) Clin. Chem. 43, 1965-1974
42. Webb, D. J., Wen, J., Lysiak, J. J., Umans, L., Van Leuven, F., and Gonias, S. L. (1996) J. Biol. Chem. 271, 24982-24988