메뉴 건너뛰기




Volumn 286, Issue 3 55-3, 2004, Pages

Concerted effect of transforming growth factor-β, cyclin inhibitor p21, and c-myc on smooth muscle cell proliferation

Author keywords

Antisense oligonucleotide; Antisense plasmid DNA; Atherosclerosis; Cancer; Gene overexpression; Reverse transcriptase polymerase chain reaction

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MYC PROTEIN; PLASMID DNA; PROTEIN P21; TRANSFORMING GROWTH FACTOR BETA;

EID: 1342283050     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00462.2003     Document Type: Article
Times cited : (19)

References (63)
  • 2
    • 0035011486 scopus 로고    scopus 로고
    • Integrating Myc and TGF-β signalling in cell-cycle control
    • Amati B. Integrating Myc and TGF-β signalling in cell-cycle control. Nat Cell Biol 3: E112-E113, 2001.
    • (2001) Nat Cell Biol , vol.3
    • Amati, B.1
  • 3
    • 0027938417 scopus 로고
    • Down-regulation of the c-myc proto-oncogene in inhibition of vascular smooth-muscle cell proliferation: A signal for growth arrest?
    • Bennett MR, Littlewood TD, Hancock DC, Evan GI, and Newby AC. Down-regulation of the c-myc proto-oncogene in inhibition of vascular smooth-muscle cell proliferation: a signal for growth arrest? Biochem J 302: 701-708, 1994.
    • (1994) Biochem J , vol.302 , pp. 701-708
    • Bennett, M.R.1    Littlewood, T.D.2    Hancock, D.C.3    Evan, G.I.4    Newby, A.C.5
  • 4
    • 0020993055 scopus 로고
    • Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours
    • Bernard O, Cory S, Gerondakis S, Webb E, and Adams JM. Sequence of the murine and human cellular myc oncogenes and two modes of myc transcription resulting from chromosome translocation in B lymphoid tumours. EMBO J 2: 2375-2383, 1983.
    • (1983) EMBO J , vol.2 , pp. 2375-2383
    • Bernard, O.1    Cory, S.2    Gerondakis, S.3    Webb, E.4    Adams, J.M.5
  • 5
    • 0029952051 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of rat arterial smooth muscle cell clones: Implications for the development of experimental intimal thickening
    • Bochaton-Piallat ML, Ropraz P, Gabbiani F, and Gabbiani G. Phenotypic heterogeneity of rat arterial smooth muscle cell clones: implications for the development of experimental intimal thickening. Arterioscler Thromb Vasc Biol 16: 815-820, 1996.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 815-820
    • Bochaton-Piallat, M.L.1    Ropraz, P.2    Gabbiani, F.3    Gabbiani, G.4
  • 8
    • 0028815552 scopus 로고
    • Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty
    • Chang MW, Barr E, Lu MM, Barton K, and Leiden JM. Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J Clin Invest 96: 2260-2268, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 2260-2268
    • Chang, M.W.1    Barr, E.2    Lu, M.M.3    Barton, K.4    Leiden, J.M.5
  • 9
    • 0037067653 scopus 로고    scopus 로고
    • E2F4/5 and p107 as Smad cofactors linking the TGF-β receptor to c-myc repression
    • Chen CR, Kang Y, Siegel PM, and Massague J. E2F4/5 and p107 as Smad cofactors linking the TGF-β receptor to c-myc repression. Cell 110: 19-32, 2002.
    • (2002) Cell , vol.110 , pp. 19-32
    • Chen, C.R.1    Kang, Y.2    Siegel, P.M.3    Massague, J.4
  • 11
    • 0031826446 scopus 로고    scopus 로고
    • Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells
    • Chen HW and Huang HC. Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells. Br J Pharmacol 124: 1029-1040, 1998.
    • (1998) Br J Pharmacol , vol.124 , pp. 1029-1040
    • Chen, H.W.1    Huang, H.C.2
  • 12
    • 0034662959 scopus 로고    scopus 로고
    • A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest
    • Claassen GF and Hann SR. A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest. Proc Natl Acad Sci USA 97: 9498-9503, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9498-9503
    • Claassen, G.F.1    Hann, S.R.2
  • 13
    • 0034816303 scopus 로고    scopus 로고
    • p21 Transgene overexpression induces a significant reduction of restenosis in hypercholesterolemic apolipoprotein E knockout mice subjected to injury of common carotid artery
    • Condorelli G, Aycock JK, Frati G, and Napoli C. p21 Transgene overexpression induces a significant reduction of restenosis in hypercholesterolemic apolipoprotein E knockout mice subjected to injury of common carotid artery. FASEB J 15: 2162-2170, 2001.
    • (2001) FASEB J , vol.15 , pp. 2162-2170
    • Condorelli, G.1    Aycock, J.K.2    Frati, G.3    Napoli, C.4
  • 14
    • 0028829465 scopus 로고
    • Functional analysis of the transforming growth factor-β responsive elements in the WAF/Cip1/p21 promoter
    • Datto MB, Yu Y, and Wang XP. Functional analysis of the transforming growth factor-β responsive elements in the WAF/Cip1/p21 promoter. J Biol Chem 270: 28623-28628, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 28623-28628
    • Datto, M.B.1    Yu, Y.2    Wang, X.P.3
  • 18
    • 0028917251 scopus 로고
    • Transforming growth factor-β: The key to understanding lipoprotein(a)?
    • Grainger DJ and Metcalfe JC. Transforming growth factor-β: the key to understanding lipoprotein(a)? Curr Opin Lipidol 6: 81-85, 1995.
    • (1995) Curr Opin Lipidol , vol.6 , pp. 81-85
    • Grainger, D.J.1    Metcalfe, J.C.2
  • 19
    • 0028918825 scopus 로고
    • The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis
    • Grainger DJ, Wakefield L, Bethell HW, Farndale RW, and Metcalfe JC. The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis. Nat Med 1: 74-79, 1995.
    • (1995) Nat Med , vol.1 , pp. 74-79
    • Grainger, D.J.1    Wakefield, L.2    Bethell, H.W.3    Farndale, R.W.4    Metcalfe, J.C.5
  • 21
    • 0030977841 scopus 로고    scopus 로고
    • The effect of oligonucleotides to c-myb on vascular smooth muscle cell proliferation and neointima formation after porcine coronary angioplasty
    • Gunn J, Holt CM, Francis SE, Shepherd L, Grohmann M, Newman CM, Crossman DC, and Cumberland DC. The effect of oligonucleotides to c-myb on vascular smooth muscle cell proliferation and neointima formation after porcine coronary angioplasty. Circ Res 80: 520-31, 1997.
    • (1997) Circ Res , vol.80 , pp. 520-531
    • Gunn, J.1    Holt, C.M.2    Francis, S.E.3    Shepherd, L.4    Grohmann, M.5    Newman, C.M.6    Crossman, D.C.7    Cumberland, D.C.8
  • 22
    • 0028982828 scopus 로고
    • Transforming growth factor-β1 inhibits human arterial smooth-muscle cell proliferation in a growth-rate-dependent manner
    • Halloran BG, Prorok GD, So BJ, and Baxter BT. Transforming growth factor-β1 inhibits human arterial smooth-muscle cell proliferation in a growth-rate-dependent manner. Am J Surg 170: 193-197, 1995.
    • (1995) Am J Surg , vol.170 , pp. 193-197
    • Halloran, B.G.1    Prorok, G.D.2    So, B.J.3    Baxter, B.T.4
  • 23
    • 0042190658 scopus 로고    scopus 로고
    • Arterial smooth muscle cell heterogeneity: Implications for atherosclerosis and restenosis development
    • Hao H, Gabbiani G, and Bochaton-Pialla M. Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol 23: 1510-1520, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1510-1520
    • Hao, H.1    Gabbiani, G.2    Bochaton-Pialla, M.3
  • 24
    • 0031469636 scopus 로고    scopus 로고
    • Topographical association between the cyclin-dependent kinases inhibitor P21, p53 accumulation, and cellular proliferation in human atherosclerotic tissue
    • Ihling C, Menzel G, Wellens E, Monting JS, Schaefer HE, and Zeiher AM. Topographical association between the cyclin-dependent kinases inhibitor P21, p53 accumulation, and cellular proliferation in human atherosclerotic tissue. Arterioscler Thromb Vasc Biol 17: 2218-2224, 1997.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2218-2224
    • Ihling, C.1    Menzel, G.2    Wellens, E.3    Monting, J.S.4    Schaefer, H.E.5    Zeiher, A.M.6
  • 26
    • 0031471689 scopus 로고    scopus 로고
    • Induction of vascular SMC proliferation by urokinase indicates a novel mechanism of action in vasoproliferative disorders
    • Kanse SM, Benzakour O, Kanthou C, Kost C, Lijnen HR, and Preissner KT. Induction of vascular SMC proliferation by urokinase indicates a novel mechanism of action in vasoproliferative disorders. Arterioscler Thromb Vasc Biol 17: 2848-2854, 1997.
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 2848-2854
    • Kanse, S.M.1    Benzakour, O.2    Kanthou, C.3    Kost, C.4    Lijnen, H.R.5    Preissner, K.T.6
  • 27
    • 0035570685 scopus 로고    scopus 로고
    • Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice
    • Kanwar RK, Kanwar JR, Wang D, Ormrod DJ, and Krissansen GW. Temporal expression of heat shock proteins 60 and 70 at lesion-prone sites during atherogenesis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 21: 1991-1997, 2001.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1991-1997
    • Kanwar, R.K.1    Kanwar, J.R.2    Wang, D.3    Ormrod, D.J.4    Krissansen, G.W.5
  • 28
    • 0033608385 scopus 로고    scopus 로고
    • Tacrolimus induces increased expression of transforming growth factor-β in lymphoid and non-lymphoid cells
    • Khanna A, Cairns V, and Hosenpud JD. Tacrolimus induces increased expression of transforming growth factor-β in lymphoid and non-lymphoid cells. Transplantation 67: 614-619, 1999.
    • (1999) Transplantation , vol.67 , pp. 614-619
    • Khanna, A.1    Cairns, V.2    Hosenpud, J.D.3
  • 29
    • 0033562875 scopus 로고    scopus 로고
    • CsA induces the expression of the cyclin inhibitor p21
    • Khanna A and Hosenpud J. CsA induces the expression of the cyclin inhibitor p21. Transplantation 67: 1262-1268, 1999.
    • (1999) Transplantation , vol.67 , pp. 1262-1268
    • Khanna, A.1    Hosenpud, J.2
  • 30
    • 0034663933 scopus 로고    scopus 로고
    • In vitro and in vivo transfection of p21 gene enhances cyclosporin A-mediated inhibition of lymphocyte proliferation
    • Khanna AK and Hosenpud JD. In vitro and in vivo transfection of p21 gene enhances cyclosporin A-mediated inhibition of lymphocyte proliferation. J Immunol 165: 1882-1888, 2000.
    • (2000) J Immunol , vol.165 , pp. 1882-1888
    • Khanna, A.K.1    Hosenpud, J.D.2
  • 31
    • 0030031251 scopus 로고    scopus 로고
    • Transforming growth factor-β1: Regulation with a TGF-β
    • Khanna A, Li B, Li P, and Suthanthiran M. Transforming growth factor-β1: regulation with a TGF-β1 antisense oligomer. Kidney Int Suppl 53: S2-S6, 1996.
    • (1996) Kidney Int Suppl , vol.53
    • Khanna, A.1    Li, B.2    Li, P.3    Suthanthiran, M.4
  • 33
    • 0029821728 scopus 로고    scopus 로고
    • Translocation of protein kinase C-δ by PDGF in cultured vascular smooth muscle cells: Inhibition by TGF-β 1
    • Leng L, Du B, Consigli S, and McCaffrey TA. Translocation of protein kinase C-δ by PDGF in cultured vascular smooth muscle cells: inhibition by TGF-β1. Artery 22: 140-154, 1996.
    • (1996) Artery , vol.22 , pp. 140-154
    • Leng, L.1    Du, B.2    Consigli, S.3    McCaffrey, T.A.4
  • 34
    • 0028898203 scopus 로고
    • Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect
    • Li CY, Suardet L, and Little JB. Potential role of WAF1/Cip1/p21 as a mediator of TGF-β cytoinhibitory effect. J Biol Chem 270: 4971-4974, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 4971-4974
    • Li, C.Y.1    Suardet, L.2    Little, J.B.3
  • 36
    • 10244232854 scopus 로고    scopus 로고
    • Sensitivity to transforming growth factor β1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21 induction are important early events
    • Malliri A, Yeudall WA, Nikolic M, Crouch DH, Parkinson EK, and Ozanne B. Sensitivity to transforming growth factor β1-induced growth arrest is common in human squamous cell carcinoma cell lines: c-MYC down-regulation and p21 induction are important early events. Cell Growth Differ 7: 1291-1304, 1996.
    • (1996) Cell Growth Differ , vol.7 , pp. 1291-1304
    • Malliri, A.1    Yeudall, W.A.2    Nikolic, M.3    Crouch, D.H.4    Parkinson, E.K.5    Ozanne, B.6
  • 37
    • 0031279160 scopus 로고    scopus 로고
    • Atherosclerosis, just another cancer?
    • Markowitz SD. Atherosclerosis, just another cancer? J Clin Invest 100: 2143-2145, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 2143-2145
    • Markowitz, S.D.1
  • 38
    • 0028859484 scopus 로고
    • Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β1
    • McCaffrey TA, Consigli S, Du B, Falcone DJ, Sanborn TA, Spokojny AM, and Bush HL Jr. Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β1. J Clin Invest 96: 2667-2675, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 2667-2675
    • McCaffrey, T.A.1    Consigli, S.2    Du, B.3    Falcone, D.J.4    Sanborn, T.A.5    Spokojny, A.M.6    Bush Jr., H.L.7
  • 41
    • 0027529271 scopus 로고
    • Evidence for an age-related dysfunction in the antiproliferative response to transforming growth factor-β in vascular smooth muscle cells
    • McCaffrey TA and Falcone DJ. Evidence for an age-related dysfunction in the antiproliferative response to transforming growth factor-β in vascular smooth muscle cells. Mol Biol Cell 4: 315-322, 1993.
    • (1993) Mol Biol Cell , vol.4 , pp. 315-322
    • McCaffrey, T.A.1    Falcone, D.J.2
  • 42
    • 0029070665 scopus 로고
    • Transforming growth factor-β and the protection from cardiovascular injury hypothesis
    • Metcalfe JC and Grainger DJ. Transforming growth factor-β and the protection from cardiovascular injury hypothesis. Biochem Soc Trans 23: 403-406, 1995.
    • (1995) Biochem Soc Trans , vol.23 , pp. 403-406
    • Metcalfe, J.C.1    Grainger, D.J.2
  • 45
    • 0027177398 scopus 로고
    • Transforming growth factor-β inhibits human smooth muscle cell growth and migration
    • Mii S, Ware JA, and Kent KC. Transforming growth factor-β inhibits human smooth muscle cell growth and migration. Surgery 114: 464-470, 1993.
    • (1993) Surgery , vol.114 , pp. 464-470
    • Mii, S.1    Ware, J.A.2    Kent, K.C.3
  • 47
    • 0037474452 scopus 로고    scopus 로고
    • Calcineurin-mediated pathway involved in the differentiated phenotype of smooth muscle cells
    • Ohkawa Y, Hayashi K, and Sobue K. Calcineurin-mediated pathway involved in the differentiated phenotype of smooth muscle cells. Biochem Biophys Res Commun 301: 78-83, 2003.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 78-83
    • Ohkawa, Y.1    Hayashi, K.2    Sobue, K.3
  • 48
    • 0026072875 scopus 로고
    • Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells
    • Opas M, Dziak E, Fliegel L, and Michalak M. Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells. J Cell Physiol 149: 160-171, 1991.
    • (1991) J Cell Physiol , vol.149 , pp. 160-171
    • Opas, M.1    Dziak, E.2    Fliegel, L.3    Michalak, M.4
  • 49
    • 0028132601 scopus 로고
    • Isolation of a morphologically and functionally distinct smooth muscle cell type from the intimal aspect of the normal rat aorta; evidence for smooth muscle cell heterogeneity
    • Patton WF, Erdjument-Bromage H, Marks AR, Tempst P, Taubman MB, Villaschi S, Nicosia RF, and Smith MR. Isolation of a morphologically and functionally distinct smooth muscle cell type from the intimal aspect of the normal rat aorta; evidence for smooth muscle cell heterogeneity. In Vitro Cell Dev Biol Anim 30A: 589-595, 1994.
    • (1994) In Vitro Cell Dev Biol Anim , vol.30 A , pp. 589-595
    • Patton, W.F.1    Erdjument-Bromage, H.2    Marks, A.R.3    Tempst, P.4    Taubman, M.B.5    Villaschi, S.6    Nicosia, R.F.7    Smith, M.R.8
  • 50
    • 0029160854 scopus 로고
    • Components of the protein synthesis and folding machinery are induced in vascular smooth muscle cells by hypertrophic and hyperplastic agents. Identification by comparative protein phenotyping and microsequencing
    • Patton WF, Erdjument-Bromage H, Marks AR, Tempst P, and Taubman MB. Components of the protein synthesis and folding machinery are induced in vascular smooth muscle cells by hypertrophic and hyperplastic agents. Identification by comparative protein phenotyping and microsequencing. J Biol Chem 270: 21404-21410, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 21404-21410
    • Patton, W.F.1    Erdjument-Bromage, H.2    Marks, A.R.3    Tempst, P.4    Taubman, M.B.5
  • 51
    • 0029115266 scopus 로고
    • Linoleic acid and its metabolites, hydroperoxyoctadecadienoic acids, stimulate c-Fos, c-Jun, and c-Myc mRNA expression, mitogen-activated protein kinase activation, and growth in rat aortic smooth muscle cells
    • Rao GN, Alexander RW, and Runge MS. Linoleic acid and its metabolites, hydroperoxyoctadecadienoic acids, stimulate c-Fos, c-Jun, and c-Myc mRNA expression, mitogen-activated protein kinase activation, and growth in rat aortic smooth muscle cells. J Clin Invest 96: 842-847, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 842-847
    • Rao, G.N.1    Alexander, R.W.2    Runge, M.S.3
  • 52
    • 0030596054 scopus 로고    scopus 로고
    • Stress proteins and atherosclerosis
    • Roma P and Catapano AL. Stress proteins and atherosclerosis. Atherosclerosis 127: 147-154, 1996.
    • (1996) Atherosclerosis , vol.127 , pp. 147-154
    • Roma, P.1    Catapano, A.L.2
  • 54
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A prospective for the 1990s
    • Ross R. The pathogenesis of atherosclerosis: a prospective for the 1990s. Nature 362: 801-809, 1993.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 55
    • 0028286486 scopus 로고
    • Molecular and cellular concepts in atherosclerosis
    • Sanders M. Molecular and cellular concepts in atherosclerosis. Pharmacol Ther 61: 109-153, 1994.
    • (1994) Pharmacol Ther , vol.61 , pp. 109-153
    • Sanders, M.1
  • 56
    • 0028674508 scopus 로고
    • Mechanism of transforming growth factor-β1-induced cell cycle arrest
    • Satterwhite DJ and Moses HL. Mechanism of transforming growth factor-β1-induced cell cycle arrest. Invasion Metastasis 14: 309-318, 1994.
    • (1994) Invasion Metastasis , vol.14 , pp. 309-318
    • Satterwhite, D.J.1    Moses, H.L.2
  • 57
    • 0032878291 scopus 로고    scopus 로고
    • A deletion in the gene for transforming growth factor β type I receptor abolishes growth regulation by transforming growth factor β in a cutaneous T-cell lymphoma
    • Schiemann WP, Pfeifer WM, Levi E, Kadin ME, and Lodish HF. A deletion in the gene for transforming growth factor β type I receptor abolishes growth regulation by transforming growth factor β in a cutaneous T-cell lymphoma. Blood 94: 2854-2861, 1999.
    • (1999) Blood , vol.94 , pp. 2854-2861
    • Schiemann, W.P.1    Pfeifer, W.M.2    Levi, E.3    Kadin, M.E.4    Lodish, H.F.5
  • 59
    • 0031888616 scopus 로고    scopus 로고
    • Myb proteins in life, death and differentiation
    • Weston K. Myb proteins in life, death and differentiation. Curr Opin Genet Dev 8: 76-81, 1998.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 76-81
    • Weston, K.1
  • 60
    • 0028865580 scopus 로고
    • Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions
    • Wilson E, Sudhir K, and Ives HE. Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions. J Clin Invest 96: 2364-2372, 1995.
    • (1995) J Clin Invest , vol.96 , pp. 2364-2372
    • Wilson, E.1    Sudhir, K.2    Ives, H.E.3
  • 61
    • 0026513154 scopus 로고
    • TGF-β1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector
    • Wu S, Theodorescu D, Kerbel RS, Wilson JKB, Mulder KM, Humphrey LS, and Brattain MG. TGF-β1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. J Cell Biol 116: 187-196, 1992.
    • (1992) J Cell Biol , vol.116 , pp. 187-196
    • Wu, S.1    Theodorescu, D.2    Kerbel, R.S.3    Wilson, J.K.B.4    Mulder, K.M.5    Humphrey, L.S.6    Brattain, M.G.7
  • 63
    • 0029794891 scopus 로고    scopus 로고
    • Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury
    • Yang ZY, Simari RD, Perkins ND, San H, Gordon D, Nabel GJ, and Nabel EG. Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury. Proc Natl Acad Sci USA 93: 7905-7910, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7905-7910
    • Yang, Z.Y.1    Simari, R.D.2    Perkins, N.D.3    San, H.4    Gordon, D.5    Nabel, G.J.6    Nabel, E.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.