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Volumn 163, Issue 6, 2003, Pages 1303-1311

TGF-β receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells

Author keywords

Claudin 5; Endothelial development; SB 431542; Tight junction; Vascular progenitor cells

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN; CLAUDIN; CLAUDIN 5; PHOSPHOTRANSFERASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 0347363474     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200305147     Document Type: Article
Times cited : (155)

References (26)
  • 1
    • 0037439630 scopus 로고    scopus 로고
    • Making sense of latent TGF-β activation
    • Annes, J.P., J.S. Munger, and D.B. Rifkin. 2003. Making sense of latent TGF-β activation. J. Cell Sci. 116:217-224.
    • (2003) J. Cell Sci. , vol.116 , pp. 217-224
    • Annes, J.P.1    Munger, J.S.2    Rifkin, D.B.3
  • 3
    • 0022538577 scopus 로고
    • Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors
    • Baird, A., and T. Durkin. 1986. Inhibition of endothelial cell proliferation by type β-transforming growth factor: interactions with acidic and basic fibroblast growth factors. Biochem. Biophys. Res. Commun. 138:476-482.
    • (1986) Biochem. Biophys. Res. Commun. , vol.138 , pp. 476-482
    • Baird, A.1    Durkin, T.2
  • 5
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet, P. 2000. Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6:389-395.
    • (2000) Nat. Med. , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 7
    • 0030448814 scopus 로고    scopus 로고
    • Blood vessel formation: What is its molecular basis?
    • Folkman, J., and P.A. D'Amore. 1996. Blood vessel formation: what is its molecular basis? Cell. 87:1153-1155.
    • (1996) Cell , vol.87 , pp. 1153-1155
    • Folkman, J.1    D'Amore, P.A.2
  • 8
    • 0033625416 scopus 로고    scopus 로고
    • Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice
    • Goumans, M.J., and C. Mummery. 2000. Functional analysis of the TGF-β receptor/Smad pathway through gene ablation in mice. Int. J. Dev. Biol. 44:253-265.
    • (2000) Int. J. Dev. Biol. , vol.44 , pp. 253-265
    • Goumans, M.J.1    Mummery, C.2
  • 9
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
    • Goumans, M.J., G. Valdimarsdottir, S. Itoh, A. Rosendahl, P. Sideras, and P. ten Dijke. 2002. Balancing the activation state of the endothelium via two distinct TGF-β type I receptors. EMBO J. 21:1743-1753.
    • (2002) EMBO J. , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    Ten Dijke, P.6
  • 10
    • 0036085920 scopus 로고    scopus 로고
    • SB-431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
    • Inman, G.J., F.J. Nicolas, J.F. Callahan, J.D. Harling, L.M. Gaster, A.D. Reith, N.J. Laping, and C.S. Hill. 2002. SB-431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol. Pharmacol. 62:65-74.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 65-74
    • Inman, G.J.1    Nicolas, F.J.2    Callahan, J.F.3    Harling, J.D.4    Gaster, L.M.5    Reith, A.D.6    Laping, N.J.7    Hill, C.S.8
  • 11
    • 0032528041 scopus 로고    scopus 로고
    • Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors
    • Kawabata, M., H. Inoue, A. Hanyu, T. Imamura, and K. Miyazono. 1998. Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors. EMBO J. 17:4056-4065.
    • (1998) EMBO J. , vol.17 , pp. 4056-4065
    • Kawabata, M.1    Inoue, H.2    Hanyu, A.3    Imamura, T.4    Miyazono, K.5
  • 12
    • 0037092510 scopus 로고    scopus 로고
    • Endothelial cells genetically selected from differentiating mouse embryonic stem cells incorporate at sites of neovascularization in vivo
    • Marchetti, S., C. Gimond, K. Iljin, C. Bourcier, K. Alitalo, J. Pouyssegur, and G. Pages. 2002. Endothelial cells genetically selected from differentiating mouse embryonic stem cells incorporate at sites of neovascularization in vivo. J. Cell Sci. 115:2075-2085.
    • (2002) J. Cell Sci. , vol.115 , pp. 2075-2085
    • Marchetti, S.1    Gimond, C.2    Iljin, K.3    Bourcier, C.4    Alitalo, K.5    Pouyssegur, J.6    Pages, G.7
  • 13
    • 0031695806 scopus 로고    scopus 로고
    • Genetic abnormalities in hereditary hemorrhagic telangiectasia
    • Marchuk, D.A. 1998. Genetic abnormalities in hereditary hemorrhagic telangiectasia. Curr. Opin. Hematol. 5:332-338.
    • (1998) Curr. Opin. Hematol. , vol.5 , pp. 332-338
    • Marchuk, D.A.1
  • 14
    • 0031685620 scopus 로고    scopus 로고
    • TGF-β signal transduction
    • Massague, J. 1998. TGF-β signal transduction. Annu. Rev. Biochem. 67:753-791.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 753-791
    • Massague, J.1
  • 15
    • 0033523758 scopus 로고    scopus 로고
    • Endothelial claudin: Claudin-5/TMVCF constitutes tight junction strands in endothelial cells
    • Morita, K., H. Sasaki, M. Furuse, and S. Tsukita. 1999. Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J. Cell Biol. 147:185-194.
    • (1999) J. Cell Biol. , vol.147 , pp. 185-194
    • Morita, K.1    Sasaki, H.2    Furuse, M.3    Tsukita, S.4
  • 16
    • 0036735752 scopus 로고    scopus 로고
    • Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension
    • Nishihara, A., T. Watabe, T. Imamura, and K. Miyazono. 2002. Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension. Mol. Biol. Cell. 13:3055-3063.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 3055-3063
    • Nishihara, A.1    Watabe, T.2    Imamura, T.3    Miyazono, K.4
  • 19
    • 0036888627 scopus 로고    scopus 로고
    • Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells
    • Ota, T., M. Fujii, T. Sugizaki, M. Ishii, K. Miyazawa, H. Aburatani, and K. Miyazono. 2002. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-β in human umbilical vein endothelial cells. J. Cell. Physiol. 193:299-318.
    • (2002) J. Cell. Physiol. , vol.193 , pp. 299-318
    • Ota, T.1    Fujii, M.2    Sugizaki, T.3    Ishii, M.4    Miyazawa, K.5    Aburatani, H.6    Miyazono, K.7
  • 20
    • 0033586694 scopus 로고    scopus 로고
    • Vascular cell apoptosis: Cell type-specific modulation by transforming growth factor-β1 in endothelial cells versus smooth muscle cells
    • Pollman, M.J., L. Naumovski, and G.H. Gibbons. 1999. Vascular cell apoptosis: cell type-specific modulation by transforming growth factor-β1 in endothelial cells versus smooth muscle cells. Circulation. 99:2019-2026.
    • (1999) Circulation , vol.99 , pp. 2019-2026
    • Pollman, M.J.1    Naumovski, L.2    Gibbons, G.H.3
  • 21
    • 0030952289 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis
    • Risau, W. 1997. Mechanisms of angiogenesis. Nature. 386:671-674.
    • (1997) Nature , vol.386 , pp. 671-674
    • Risau, W.1
  • 23
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger, D.R., S.J. Galli, A.M. Dvorak, C.A. Perruzzi, V.S. Harvey, and H.F. Dvorak. 1983. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science. 219:983-985.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 24
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension
    • The International PPH Consortium. 2000. Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. Nat. Genet. 26:81-84.
    • (2000) Nat. Genet. , vol.26 , pp. 81-84


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.