A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia

Circulation Research

Volumn 96, Issue 6, 2005, Pages 684-692

  Toporsian, Mourad ^a,b   Gros, Robert ^b,c   Kabir, Mohammed G ^c   Vera, Sonia ^a   Govindaraju, Karuthapillai ^d   Eidelman, David H ^d   Husain, Mansoor ^b,c   Letarte, Michelle ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

Endothelium; Superoxide; Vascular disease; Vascular tone; Vasodilatation

Indexed keywords

ANTIOXIDANT; ENDOGLIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEAT SHOCK PROTEIN 90; NITRIC OXIDE; OXYGEN; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOVENOUS MALFORMATION; ARTICLE; BLOOD VESSEL TONE; CALCIUM TRANSPORT; CAPILLARY; CARDIOVASCULAR DISEASE; CAVEOLA; CONTROLLED STUDY; ENDOTHELIUM CELL; ENG GENE; ENZYME ACTIVITY; GENE; HAPLOIDY; LIPID RAFT; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RENDU OSLER WEBER DISEASE; RESISTANCE BLOOD VESSEL; STATISTICAL SIGNIFICANCE; VASCULAR DISEASE; VASOMOTOR REFLEX; VEIN DILATATION;

ACETYLCHOLINE; ANIMALS; ANTIGENS, CD; BLOOD PRESSURE; CAVEOLIN 1; CAVEOLINS; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; HETEROZYGOTE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MEMBRANE MICRODOMAINS; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCYTES, SMOOTH MUSCLE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; NITROPRUSSIDE; PHENYLEPHRINE; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TELANGIECTASIA, HEREDITARY HEMORRHAGIC; UMBILICAL VEINS; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR RESISTANCE; VASODILATION;

EID: 16444373524     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000159936.38601.22     Document Type: Article

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