Histone deacetylase inhibitors as potent modulators of cellular contacts

Current Drug Targets

Volumn 7, Issue 6, 2006, Pages 773-787

  Vinken, Mathieu ^a   Peggy, Papeleu ^a   Vera, Rogiers ^a   Tamara, Vanhaecke ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

(Hemi)desmosome; Adherens junctions; Focal adhesion; Gap junction; Histone deacetylase inhibitor; Tight junction

Indexed keywords

4 N ACETYLDINALINE; ADENOVIRUS VECTOR; ALIPHATIC CARBOXYLIC ACID; ALPHA KETOAMIDE DERIVATIVE; ANTINEOPLASTIC AGENT; APICIDIN; BENZAMIDE DERIVATIVE; BUTYRIC ACID; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR; DIMETHYL SULFOXIDE; DOXORUBICIN; ETOPOSIDE; FR 901228; GANCICLOVIR; HEAT SHOCK PROTEIN 90 INHIBITOR; HEXAMETHYLENEBISACETAMIDE; HISTONE DEACETYLASE 1 INHIBITOR; HISTONE DEACETYLASE 2 INHIBITOR; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; KETONE DERIVATIVE; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PLAKOGLOBIN; TETRAPEPTIDE; TRAPOXIN; TRICHOSTATIN A; TRIFLUOROMETHYL KETONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VORINOSTAT;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; CANCER ADJUVANT THERAPY; CANCER CELL; CANCER INHIBITION; CELL COMMUNICATION; CELL INTERACTION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CLINICAL TRIAL; DEACETYLATION; DRUG BINDING; DRUG INDICATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME INHIBITION; EPIGENETICS; EXTRACELLULAR MATRIX; GAP JUNCTION; GENE EXPRESSION PROFILING; HOMEOSTASIS; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; TIGHT JUNCTION; UNSPECIFIED SIDE EFFECT; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; ANTINEOPLASTIC AGENTS; ENZYME INHIBITORS; HISTONE DEACETYLASES; HUMANS; INTERCELLULAR JUNCTIONS; MOLECULAR STRUCTURE; NEOPLASMS;

EID: 33744804024     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945006777435281     Document Type: Review

References (234)

1. Thiery, J.P. (2003) Curr. Opin. Genet. Dev., 13(4), 365-371.
2. Lodish, H.; Berk, A.; Matsudaira, P.; Kaiser, C.A.; Scott, M.P.; Zipursky, S.L. and Darnell, J. (2003) Molecular Cell Biology, W.H. Freeman and Company, New York.
3. Akiyama, T. (2000) Cytokine Growth Factor Rev., 11(4), 273-282.
4. Balda, M.S. and Matter, K. (2003) Trends Cell Biol., 13(6), 310-318.
5. Doble, B.W.; Dang, X.; Ping, P.; Fandrich, R.R.; Nickel, B.E.; Jin, Y.; Cattini, P.A. and Kardami, E. (2004) J. Cell Sci., 117(3), 507-514.
6. Guillemot, L.; Hammar, E.; Kaister, C.; Ritz, J.; Caille, D.; Jond, L.; Bauer, C.; Meda, P. and Citi, S. (2004) J. Cell Sci., 117(22), 5245-5256.
7. Cavallaro, U. and Christofori, G. (2004) Nat. Rev. Cancer, 4(2), 118-132.
8. Christofori, G. (2003) EMBO J., 22(10), 2318-2323.
9. Nair, K.S.; Naidoo, R. and Chetty, R. (2005) J. Clin. Pathol., 58(4), 343-351.
10. Hajra, K.M. and Fearon, E.R. (2002) Genes Chromosomes Cancer, 34(3), 255-268.
11. Strathdee, G. (2002) Semin. Cancer Biol., 12(5), 373-379.
12. Yamasaki, H.; Omori, Y.; Kurtovskikh, V.; Zhu, W.; Mironov, N.; Yamakage, K. and Mesnil, M. (1999) Novartis Found. Symp., 219, 241-260.
13. Cress, W.D. and Seto, E. (2000) J. Cell. Physiol., 184(1), 1-16.
14. Drummond, D.C.; Noble, C.O.; Kirpotin, D.B.; Guo, Z.; Scott, G.K. and Benz, C.C. (2005) Annu. Rev. Pharmacol. Toxicol., 45, 495-528.
15. Mai, A.; Massa, S.; Rotili, D.; Cerbara, I.; Valente, S.; Pezzi, R.; Simeoni, S. and Ragno, R. (2005) Med. Res. Rev., 25(3), 261-309.
16. Marks, P.A.; Richon, V.M. and Rifkind, R.A. (2000) J. Natl. Cancer Inst., 92(15), 1210-1216.
17. Papeleu, P., Vanhaecke, T.; Elaut, G.; Vinken, M.; Henkens, T.; Snykers, S. and Rogiers, V. (2005) Crit. Rev. Toxicol ., 35(4), 363-378.
18. Vanhaecke, T.; Papeleu, P.; Elaut, G. and Rogiers, V. (2004) Curr. Med. Chem., 11(12), 1629-1643.
19. Chiba, T.; Yokosuka, O.; Arai, M.; Tada, M.; Fukai, K.; Imazeki, F.; Kato, M.; Seki, N. and Saisho, H. (2004) J. Hepatol., 41(3), 436-445.
20. Chiba, T.; Yokosuka, O.; Fukai, K.; Kojima, H.; Tada, M.; Arai, M.; Imazeki, F. and Saisho, H. (2004) Oncology, 66(6), 481-491.
21. Germann, A.; Dihlmann, S.; Hergenhahn, M.; Doeberitz, M.K. and Koesters, R. (2003) Int. J. Cancer, 106(2), 187-197.
22. Gray, S.G.; Qian, C.N.; Furge, K.; Guo, X. and Teh, B.T. (2004) Int. J. Oncol., 24(4), 773-795.
23. Mariadason, J.M.; Corner, G.A. and Augenlicht, L.H. (2000) Cancer Res., 60(16), 4561-4572.
24. Sasakawa, Y.; Naoe, Y.; Sogo, N.; Inoue, T.; Sasakawa, T.; Matsuo, M.; Manda, T. and Mutoh, S. (2005) Biochem. Pharmacol., 69(4), 603-616.
25. Sato, N.; Fukushima, N.; Maitra, A.; Matsubayashi, H.; Yeo, C.J.; Cameron, J.L.; Hruban, R.H. and Goggins, M. (2003) Cancer Res., 63(13), 3735-3742.
26. Yamashita, Y.; Shimada, M.; Harimoto, N.; Tanaka, S.; Shirabe, K.; Ijima, K.; Nakazawa, K.; Fukuda, J.; Funatsu, K. and Maehara, Y. (2004) Cell Transplant., 13(7-8), 793-799.
27. Bock, E. (1991) Biochem. Soc. Trans., 19(4), 1076-1080.
28. Geiger, B. and Ayalon, O. (1992) Annu. Rev. Cell Biol., 8, 307-332.
29. Hynes, R.O. and Lander, A.D. (1992) Cell, 68(2), 303-322.
30. Juliano, R.L. (2002) Annu. Rev. Pharmacol. Toxicol., 42, 283-323.
31. Takeichi, M. (1990) Annu. Rev. Biochem., 59, 237-252.
32. Chothia, C. and Jones, E.Y. (1997) Annu. Rev. Biochem., 66, 823-862.
33. Angst, B.D.; Marcozzi, C. and Magee, A.I. (2001) J. Cell Sci., 114(4), 625-626.
34. Blaschuk, O.W. and Rowlands, T.M. (2002) Mol. Membr. Biol., 19(2), 75-80.
35. Gooding, J.M.; Yap, K.L. and Ikura, M. (2004) Bioessays, 26(5), 497-511.
36. Magee, A.I. and Buxton, R.S. (1991) Curr. Opin. Cell Biol., 3(5), 854-861.
37. Nagafuchi, A. (2001) Curr. Opin. Cell Biol., 13(5), 600-603.
38. Takeichi, M. (1995) Curr. Opin. Cell Biol., 7(5), 619-627.
39. Wheelock, M.J. and Johnson, K.R. (2003) Annu. Rev. Cell. Dev. Biol., 19, 207-235.
40. Getsios, S.; Huen, A.C. and Green K.J. (2004) Nat. Rev. Mol. Cell Biol., 5(4), 271-281.
41. Green, K.J. and Gaudry, C.A. (2000) Nat. Rev. Mol. Cell Biol., 1(3), 208-216.
42. Huber, O. (2003) Cell. Mol. Life Sci., 60(9), 1872-1890.
43. Gonzalez-Mariscal, L.; Betanzos, A.; Nava, P. and Jaramillo, B.E. (2003) Prog. Biophys. Mol. Biol., 81(1), 1-44.
44. Matter, K. and Balda, M.S. (2003) Nat. Rev. Mol. Cell Biol., 4(3), 225-236.
45. Mitic, L.L. and Anderson, J.M. (1998) Annu. Rev. Physiol., 60, 121-142.
46. Schneeberger, E.E. and Lynch, R.D. (2004) Am. J. Physiol. Cell Physiol., 286(6), C1213-C1228.
47. Cohen, C.J.; Shieh, J.T.; Picles, R.J.; Okegawa, T.; Hsieh, J.T. and Bergelson, J.M. (2001) Proc. Natl. Acad. Sci. U.S.A., 98(26), 15191-15196.
48. Ebnet, K.; Suziki, A.; Ohno, S. and Vestweber, D. (2004) J. Cell Sci., 117(1), 19-29.
49. Tsukita, S.; Furuse, M. and Itoh, M. (2001) Nat. Rev. Mol. Cell Biol., 2(4), 285-293.
50. D'Atri, F. and Citi, S. (2002) Mol. Membr. Biol., 19(2), 103-112.
51. Gonzalez-Mariscal, L.; Betanzos, A. and Avila-Flores, A. (2000) Semin. Cell Dev. Biol., 11(4), 315-324.
52. Martin, P.E. and Evans, W.H. (2004) Cardiovasc. Res., 62(2), 378-387.
53. Musil, L.S.; Le, A.C.; VanSlyke, J.K. and Roberts, L.M. (2000) J. Biol. Chem., 275(33), 25207-25207.
54. Goodenough, D.A. and Paul, D.L. (2003) Nat. Rev. Mol. Cell Biol., 4(4), 285-294.
55. Sohl, G. and Willecke, K. (2003) Cell. Commun. Adhes., 10(4-6), 173-180.
56. Sohl, G. and Willecke, K. (2004) Cardiovasc. Res., 62(2), 228-232.
57. Alexander, D.B. and Goldberg, G.S. (2003) Curr. Med. Chem., 10(19), 2045-2058.
58. Giles, R.H.; van Es, J.H. and Clevers, H. (2003) Biochim. Biophys. Acta, 1653(1), 1-24.
59. Sharpe, C.; Lawrence, N. and Martinez Arias, A. (2001) Bioessays, 23(4), 311-318.
60. Miravet, S.; Piedra, J.; Miro, F.; Itarte, E.; Garcia de Herreros, A. and Dunach, M. (2002) J. Biol. Chem., 277(3), 1884-1891.
61. Daniel, J.M. and Reynolds, A.B. (1999) Mol. Cell. Biol., 19(5), 3614-3623.
62. Betanzos, A.; Huerta, M.; Lopez-Bayghen, E.; Azuara, E.; Amerena, J. and Gonzalez-Mariscal, L. (2004) Exp. Cell Res., 292(1), 51-66.
63. Gottardi, C.J.; Arpin, M.; Fanning, A.S. and Louvard, D. (1996) Proc. Natl. Acad. Sci. U.S.A., 93(20), 10779-10784.
64. Dang, X.; Doble, B.W. and Kardami, E. (2003) Mol. Cell. Biochem., 242(1-2), 35-38.
65. Moorby, C. and Patel, M. (2001) Exp. Cell Res., 271(2), 238-248.
66. Woods, A. and Couchman, J.R. (2001) Curr. Opin. Cell Biol., 13(5), 578-583.
67. Alahari, S.K.; Reddig, P.J. and Juliano, R.L. (2002) Int. Rev. Cytol., 220, 145-184.
68. Goel, J.L. and Languino, L.R. (2004) Cancer Treat. Res., 119, 15-31.
69. Boudreau, N.J. and Jones, P.L. (1999) Biochem. J., 339(3), 481-488.
70. Danen, E.H. (2005) Curr. Pharm. Des., 11(7), 881-891.
71. Couchman, J.R.; Chen, L. and Woods, A. (2001) Int. Rev. Cytol., 207, 113-150.
72. Couchman, J.R. (2003) Nat. Rev. Mol. Cell Biol., 4(12), 926-937.
73. Woods, A. and Couchman, J.R. (1998) Trends Cell Biol., 8(5), 189-192.
74. Beauvais, D.M. and Rapraeger, A.C. (2004) Reprod. Biol. Endocrinol., 2(3), 1-12.
75. Carey, D.J. (1997) Biochem. J., 327(1), 1-16.
76. Tkachenko, R.; Rhodes, J.M. and Simons, M. (2005) Circ. Res., 96(5), 488-500.
77. Green, K.J. and Jones, J.C. (1996) FASEB J., 10(8), 871-881.
78. Jones, J.C.; Hopkinson, S.B. and Goldfinger, L.E. (1998) Bioessays, 20(6), 488-494.
79. Nievers, M.G.; Schaapveld, R.Q. and Sonnenberg, A. (1999) Matrix Biol., 18(1), 5-17.
80. Wozniak, M.A.; Modzelewska, K.; Kwong, L. and Keely, P.J. (2004) Biochim. Biophys. Acta, 1692(2-3), 103-119.
81. Kornberg, L.J. (1998) Head Neck, 20(8), 745-752.
82. Mitra, S.K.; Hanson, D.A. and Schlaepfer, D.D. (2005) Nat. Rev. Mol. Cell Biol., 6(1), 56-68.
83. Petit, V. and Thiery, J.P. (2000) Biol. Cell., 92(7), 477-494.
84. Wehrle-Haller, B. and Imhof, B. (2002) Trends Cell Biol., 12(8), 382-389.
85. Couchman, J.R. and Woods, A. (1999) J. Cell Sci ., 112(20), 3415-3420.
86. Zimmermann, P. and David, G. (1999) FASEB J., 13, S91-S100.
87. Chidgey, M. (2002) Histol. Histopathol., 17(4), 1179-1192.
88. Conacci-Sorrell, M.; Zhurinsky, J. and Ben-Ze'ev, A. (2002) J. Clin. Invest., 109(8), 987-991.
89. Martin, T.A. and Jiang, W.G. (2001) Histol. Histopathol., 16(4), 1183-1195.
90. Morin, P.J. (2005) Cancer Res., 65(21), 9603-9606.
91. Sawada, N.; Murata, M.; Kikuchi, K.; Osanai, M.; Tobioka, H.; Kojima, T. and Chiba, H. (2003) Med. Electron. Microsc., 36(3), 147-156.
92. Trosko, J.E. and Ruch, R.J. (2002) Curr. Drug Targets, 3(6), 465-482.
93. Luu, H.H.; Zhang, R.; Haydon, R.C.; Rayburn, E.; Kang, Q.; Park, J.K.; Wang, H.; Peng, Y.; Jiang, W. and He, T.C. (2004) Curr. Cancer Drug Targets, 4(8), 653-671.
94. Hirohashi, S. and Kanai, Y. (2003) Cancer Sci., 94(7), 575-581.
95. Chin, D.; Boyle, G.M.; Kane, A.J.; Theile, D.R.; Hayward, N.K.; Parson, P.G. and Coman, W.B. (2005) Br. J. Plast. Surg., 58(4), 466-474.
96. Park, H.; Kim, Y.; Lim, Y.; Han, I. and Oh, E.S. (2002) J. Biol. Chem., 277(33), 29730-29736.
97. Cavallaro, E. (2004) Curr. Opin. Investig. Drugs, 5(12), 1274-1278.
98. Oyamada, M.; Krutovskikh, V.A.; Mesnil, M.; Partensky, C.; Berger, F. and Yamasaki, H. (1990) Mol. Carcinog., 3(5), 273-278.
99. Carrozzino, F.; Soulie, P.; Huber, D.; Mensi, N.; Orci, L.; Cano, A.; Feraille, E. and Montesano, R. (2005) Am. J. Physiol. Cell Physiol., 289(4), 1002-1014.
100. Ikenouchi, J.; Matsuda, M.; Furuse, M. and Tsukita, S. (2003) J. Cell Sci., 116(10), 1959-1967.
101. Ohkubo, T. and Ozawa, M. (2004) J. Cell Sci., 117(9), 1675-1685.
102. Peinado, H.; Ballestar, E.; Esteller, M. and Cano, A. (2004) Mol. Cell. Biol., 24(1), 306-319.
103. Vandewalle, C.; Comijn, J.; De Craene, B.; Vermassen, P.; Bruyneel, E.; Andersen, H.; Tulchinsky, E.; Van Roy, F. and Berx, G. (2005) Nucleic Acids Res., 33(20), 6566-6578.
104. Moggs, J.G.; Goodman, J.I.; Trosko, J.E. and Roberts, R.A. (2004) Toxicol. Appl. Pharmacol., 196(3), 422-430.
105. Nakao, M. (2001) Gene, 278(1-2), 25-31.
106. Szyf, M. (2003) Ageing Res., 2(3), 299-328.
107. Szyf, M.; Pakneshan, P. and Rabbani, S.A. (2004) Cancer Lett., 211(2), 133-143.
108. Dokmanovic, M. and Marks, P.A. (2005) J. Cell. Biochem., 96(2), 293-304.
109. Sengupta, N. and Seto, E. (2004) J. Cell. Biochem., 93(1), 57-67.
110. Somech, R.; Izraeli, S.J. and Simon, A. (2004) Cancer Treat. Rev., 30(5), 461-472.
111. Vanhaecke, T.; Henkens, T.; Kass, G.E. and Rogiers, V. (2004) Biochem. Pharmacol., 68(4), 753-760.
112. Weidle, U.H. and Grossmann, A. (2000) Anticancer Res., 20(3), 1471-1485.
113. Roth, S.Y.; Denu, J.M. and Allis, C.D. (2001) Annu. Rev. Biochem., 70, 81-120.
114. Dangond, F.; Henriksson, M.; Zardo, G.; Caiafa, P.; Ekstrom, T.J. and Gray, S.G. (2002) Int. J. Oncol., 19(4), 773-777.
115. Gray, S.G. and Ekstrom, T.J. (2001) Exp. Cell Res., 262(2), 75-83.
116. Grozinger, C.M.; Hassig, C.A. and Schreiber, S.L. (1999) Proc. Natl. Acad. Sci. U.S.A., 96(9), 4868-4873.
117. Finnin, M.S.; Donigian, J.R.; Cohen, A.; Richon, V.M.; Rifkind, R.A.; Marks, P.A.; Breslow, R. and Pavletich, N.P. (1999) Nature, 401(6749), 188-193.
118. Frye, R.A. (1999) Biochem. Biophys. Res. Commun., 260(1), 273-279.
119. Glaser, K.B.; Staver, M.J.; Waring, J.F.; Stender, J.; Ulrich, R.G. and Davidsen, S.K. (2003) Mol. Cancer Ther., 2(2), 151-163.
120. Marks, P.A.; Miller, R. and Richon, V.M. (2003) Curr. Opin. Pharmacol., 3(4), 344-351.
121. Van Lint, C.; Emiliani, S. and Verdin, E. (1996) Gene Expr., 5(4-5), 245-253.
122. Villar-Garea, A. and Esteller, M. (2004) Int. J. Cancer, 112(2), 171-178.
123. Maeda, T.; Towatari, M.; Kosugi, H. and Saito, H. (2000) Blood, 96(12), 3847-3856.
124. Magner, W.J.; Kazim, A.L.; Stewart, C.; Romano, M.A.; Catalano, G.; Grande, C.; Keiser, N.; Santaniello, F. and Tomasi, T.B. (2000) J. Immunol., 165(12), 7012-7024.
125. Suenaga, M.; Soda, H.; Oka, M.; Yamaguchi, A.; Nakatomi, K.; Shiozawa, K.; Kawabata, S.; Kasai, T.; Yamada, Y.; Kamihira, S.; Tei, C. and Kohno, S. (2002) Int. J. Cancer, 97(5), 621-625.
126. Wu P.; Meng, L.; Wang, H.; Zhou, J.; Xu, G.; Wang, S.; Xi, L.; Chen, G.; Wang, B.; Zhu, T.; Lu, Y. and Ma, D. (2005) Biochem. Biophys. Res. Commun., 335(1), 36-44.
127. Kwon, H.J.; Kim, M.S.; Kim, M.J.; Nakajima, H. and Kim, K.W. (2002) Int. J. Cancer, 97(3), 290-296.
128. Sasakawa, Y.; Naoe, Y.; Inoue, T.; Sasakawa, T.; Matsuo, M.; Manda, T. and Mutoh, S. (2002) Biochem. Pharmacol., 64(7), 1079-1090.
129. Sasakawa, Y.; Naoe, Y.; Noto, T.; Inoue, T.; Sadakawa, T.; Matsuo, M.; Manda, T. and Mutoh, S. (2003) Biochem. Pharmacol., 66(6), 897-906.
130. Sawa, H.; Murakami, H.; Murakami, M.; Yamazaki, I.; Tamura, Y.; Mima, T.; Satone, A.; Ide, W.; Hashimoto, I. and Kamada, H. (2002) Brain Tumor Pathol., 19(2), 77-81.
131. Arterburn, L.M.; Zurlo, J.; Yager, J.D.; Overton, R.M. and Heifetz, A.H. (1995) Hepatology, 22(1), 175-187.
132. Isom, H.C.; Secott, T.; Georgoff, I.; Woodworth, C. and Mummaw, J. (1985) Proc. Natl. Acad. Sci. U.S.A., 82(10), 3252-3256.
133. Kojima, T.; Mitaka, T.; Mizuguchi, T. and Mochizuki, Y. (1996) Carcinogenesis, 17(3), 537-544.
134. Yoshizawa, T.; Watanabe, S.; Hirose, M.; Miyazaki, A. and Sato, N. (1997) J. Gastroenterol. Hepatol., 12(4), 325-330.
135. Ogawa, T.; Hayashi, T.; Kyoizumi, S.; Ito, T.; Trosko, J.E. and Yorioka, N. (1999) Lab. Invest., 79(12), 1511-1520.
136. Ogawa, T.; Hayashi, T.; Yorioka, N.; Kyoizumi, S. and Trosko, J.E. (2001) Kidney Int., 60(3), 996-1008.
137. Engelmann, G.L.; Staecker, J.L. and Richardson, A.G. (1987) In Vitro Cell. Dev. Biol., 23(2), 86-92.
138. Gladhaug, I.P.; Refsnes, M.; Sand, T.E. and Christoffersen, T. (1988) Cancer Res., 48(22), 6560-6564.
139. Iwai, M.; Tanaka, S.; Mori, T.; Harada, Y.; Muramatsu, A.; Morikawa, T.; Kashima, K. and Fushiki, S. (2002) Cell Biol. Toxicol., 18(3), 147-156.
140. Staecker, J.L.; Sattler, C.A. and Pitot, H.C. (1988) J. Cell. Physiol., 135(3), 367-376.
141. Han, J.W.; Ahn, S.H.; Park, R.H.; Wang, S.Y.; Bae, G.U.; Seo, D.W.; Kwon, H.K.; Hong, S.; Lee, H.Y.; Lee, Y.W. and Lee, H.W. (2000) Cancer Res., 60(21), 6068-6074.
142. Hoshikawa, Y.; Kwon, H.J.; Yoshida, M.; Horinouchi, S. and Beppu, T. (1994) Exp. Cell Res., 214(1), 189-197.
143. Huang, L. and Pardee, A.B. (2000) Mol. Med., 6(10), 849-866.
144. Saito, A.; Yamashita, T.; Mariko, Y.; Nosaka, Y.; Tsuchiya, K.; Ando, T.; Suzuli, T.; Tsuruo, T. and Nakanishi, O. (1999) Proc. Natl. Acad. Sci. U.S.A., 96(8), 4592-4597.
145. Primeau, M., Gagnon, J. and Momparler, R.L. (2003) Int. J. Cancer, 103(2), 177-184.
146. Strait, K.A.; Dabbas, B.; Hammond, E.H.; Warnick, C.T.; Iistrup, S.J. and Ford, C.D. (2002) Mol. Cancer Ther., 1(13), 1181-1190.
147. Wakabayashi, K.; Saito, H.; Kaneko, F.; Nakamoto, N.; Tada, S. and Hibi, T. (2005) Int. J. Oncol., 26(1), 233-239.
148. Barshishat, M.; Polak-Charcon, S. and Schwartz, B. (2000) Br. J. Cancer, 82(1), 195-203.
149. Canes, D.; Chiang, G.J.; Billmeyer, B.R.; Austin, C.A.; Kosakowski, M.; Rieger-Christ, K.M.; Libertino, J.A. and Summerhayes, I.C. (2005) Int. J. Cancer, 113(5), 841-848.
150. Kovarikova, M.; Pachernik, J.; Hofmanova, J.; Zadak, Z. and Kozubik, A. (2000) Eur. J. Cancer, 36(14), 1844-1852.
151. Masuda, T.; Saito, H.; Kaneko, F.; Atsuwaka, K.; Morita, M.; Inagaki, H.; Kumagai, N.; Tsuchimoto, K. and Ishii, A.H. (2000) In Vitro Cell. Dev. Biol. Anim., 36(6), 387-394.
152. Ohira, T.; Gemmill, R.M.; Fergson, K.; Kusy, S.; Roche, J.; Brambilla, E.; Zeng, C.; Baron, A.; Bemis, L.; Erickson, P.; Wilder, E.; Rustgi, A.; Kitajewski, J.; Gabrielson, E.; Bremnes, R.; Franklin, W. and Drabkin, H.A. (2003) Proc. Natl. Acad. Sci. U.S.A., 100(18), 10429-10434.
153. Phiel, C.J.; Zhang, F.; Huang, E.Y.; Guenther, M.G.; Lazar, M.A. and Klein, P.S. (2001) J. Biol. Chem., 276(39), 36734-36741.
154. Shim, J.S.; Kim, D.H. and Kwon, H.J. (2004) Oncogene, 23(9), 1704-1711.
155. Schroder, C.; Eckert, K. and Maurer, H.R. (1998) Int. J. Oncol., 13(6), 1335-1340.
156. Takai, N.; Desmond, J.C.; Kumagai, T.; Gui, D.; Said, J.W.; Whittaker, S.; Miyakawa, I. and Koeffler, H.P. (2004) Clin. Cancer Res., 10(3), 1141-1149.
157. Takai, N.; Kawamata, N.; Gui, D.; Said, J.W.; Miyakawa, I. and Koeffler, H.P. (2004) Cancer, 101(12), 2760-2770.
158. Takai, N.; Ueda, T.; Nishida, M.; Nasu, K. and Narahara, H. (2006) Gynecol. Oncol., 101(1), 108-113.
159. Vincan, E.; Leet, C.S.; Reyes, N.I.; Dilley, R.J.; Thomas, R.J. and Phillips, W.A. (2000) Oncol. Res., 12(4), 193-201.
160. Winn, R.A.; Bremnes, R.M.; Bemis, L.; Franklin, W.A.; Miller, Y.E.; Cool, C. and Heasley, L.E. (2002) Oncogene, 21(49), 7497-7506.
161. Wolter, F. and Stein, J. (2002) J. Nutr., 132(7), 2082-2086.
162. Kim, Y.; Park, H.; Lim, Y.; Han, I.; Kwon, H.J.; Woods, A. and Oh, S.E. (2003) Oncogene, 22(6), 826-830.
163. Koizume, S.; Tachibana, K. and Shiraishi, M. (2003) Biol. Chem., 384(5),787-790.
164. Emanuele, S.; D'Anneo, A.; Bellavia, G.; Vassallo, B.; Lauricella, M.; De Blasio, A.; Vento, R. and Tesorieri, G. (2004) Eur. J. Cancer, 40(9), 1441-1452.
165. Fukuda, K. (1999) Int. J. Biochem. Cell Biol., 31(3-4), 519-529.
166. Kondo, K.; Kohno, N.; Yokoyama, A. and Hiwada, K. (1998) Cancer Res., 58(9), 2014-2019.
167. Ramsay, R.G.; Ciznadija, D.; Sicurella, C.; Reyes, N.; Mitchelhill, K.; Darcy, P.K.; D'Abaco, G. and Mantamadiotis, T. (2005) DNA Cell Biol., 24(1), 21-29.
168. Bordonaro, M.; Mariadson, J.M.; Aslam, F.; Heerdt, B.G. and Augenlicht, L.H. (1999) Cell Growth Differ., 10(10), 713-720.
169. Bordonaro, M.; Lazarova, D.L.; Augenlicht, L.H. and Sartorelli, A.C. (2002) Int. J. Cancer, 97(1), 42-51.
170. Wilson, A.J.; Velcich, A.; Arango, D.; Kurland, A.R.; Shenoy, S.M.; Pezo, R.C.; Levsky, J.M.; Singer, R.H. and Augenlicht, L.H. (2002) Cancer Res., 62(21), 6006-6010.
171. El-Zawahry, A.; Lu, P.; White, S.J. and Voelkel-Johnson, C. (2006) Cancer Gene Ther., 13(3), 281-289.
172. Goldsmith, M.E.; Kitazono, M.; Fok, P.; Aikou, T.; Bates, S. and Fojo, T. (2003) Clin. Cancer Res., 9(14), 5394-53401.
173. Hemminki, A.; Kanerva, A.; Liu, B.; Wang, M.; Alvarez, R.D.; Siegal, G.P. and Curiel, D.T. (2003) Cancer Res., 63(4), 847-853.
174. Kitazono, M.; Goldschmith, M.E.; Aikou, T.; Bates, S. and Fojo, T. (2001) Cancer Res., 61(17), 6328-6330.
175. Kitazono, M.; Rao, V.K.; Robey, R.; Aikou, T.; Bates, S.; Fojo, T. and Goldschmith, M.E. (2002) Blood, 99(6), 2248-2251.
176. Lai, Y.L.; Pong, R.C.; McConnell, J.D. and Hsieh, J.T. (2003) Biotechniques, 35(1), 186-194.
177. Lee, C.T.; Seol, J.Y.; Park, K.H.; Yoo, C.G.; Kim, Y.W.; Ahn, C.; Song, Y.W.; Han, S.K.; Han, J.S.; Kim, S.; Lee, J.S. and Shim, Y.S. (2001) Clin. Cancer Res., 7(1), 210-214.
178. Okegawa, T.; Nutahara, K.; Pong, R.C.; Higashihara, E. and Hsieh, J.T. (2005) J. Urol., 174(2), 747-752.
179. Pong, R.C.; Lai, Y.J.; Chen, H.; Okegawa, T.; Frenkel, E.; Sagalowsky, A. and Hsieh, J.T. (2003) Cancer Res., 63(24), 8680-8686.
180. Sachs, M.D.; Ramamurthy, M.; Ple, H.; Wickham, T.J.; Lamfers, M.; Gerritsen, W.; Chowdhury, W.; Li, Y.; Schoenberg, M.P. and Rodriguez, R. (2004) Cancer Gene Ther., 11(7), 477-486.
181. Taura, K.; Yamamoto, Y.; Nakajima, A.; Hata, K.; Uchinami, H.; Yonezawa, K.; Hatano, E.; Nishino, N. and Yamaoka, Y. (2004) J. Gene Med., 6(5), 526-536.
182. Bordin, M.; D'Atri, F.; Guillemot, L. and Citi, S. (2004) Mol. Cancer Res., 2(12), 692-701.
183. Ohata, A.; Usami, M. and Miyoshi, M. (2005) Nutrition, 21(7-8), 838-847.
184. Yamashita, Y.; Shimada, M.; Harimoto, N.; Rikimaru, T.; Shirabe, K.; Tanaka, S. and Sugimachi, K. (2003) Int. J. Cancer, 103(5), 572-576.
185. Ammerpohl, O.; Thormeyer, D.; Khan, Z.; Appelskog, I.B.; Gojkovic, Z.; Almqvist, P.M. and Ekstrom, T.J. (2004) Biochem. Biophys. Res. Commun., 324(1), 8-14.
186. Asklund, T.; Appelskog, I.B.; Ammerpohl, O.; Ekstrom, T.J. and Almqvist, P.M. (2004) Eur. J. Cancer, 40(7), 1073-1081.
187. Ogawa, T.; Hayashi, T.; Tokunou, M.; Nakachi, K.; Trosko, J.E.; Chang, C.C. and Yorioka, N. (2005) Cancer Res., 65(21), 9771-9778.
188. Robe, P.A.; Jolois, O.; N'Guyen, M.; Princen, F.; Malgrange, B.; Merville, M.P. and Bours, V. (2004) Int. J. Oncol., 25(1), 187-192.
189. Ishihara, K.; Hong, J.; Zee, O. and Ohuchi, K. (2004) Br. J. Pharmacol., 142(6), 1020-1030.
190. Lin, K.T.; Yeh, S.H.; Chen, D.S.; Chen, P.J. and Jou, Y.S. (2005) J. Biomed. Sci., 12(5), 803-813.
191. Lim, Y.; Han, I.; Kwon, H.J. and Oh, E.S. (2002) J. Biol. Chem., 277(15), 12735-12740.
192. Rishikof, D.C.; Ricupero, D.A.; Liu, H. and Goldstein, R.H. (2004) J. Cell. Biochem., 91(4), 740-748.
193. Rombouts, K.; Niki, T.; Greenwel, P.; Vandermonde, A.; Wielant, A.; Hellemans, K.; De Bleser, P.; Yoshida, M.; Schuppan, D.; Rojkind, M. and Geerts, A. (2002) Exp. Cell Res., 278(2), 184-197.
194. Niki, T.; Rombouts, K.; De Bleser, P.; De Smet, K.; Rogiers, V.; Schuppan, D.; Yoshida, M.; Gabbiani, G. and Geerts, A. (1999) Hepatology, 29(3), 858-867.
195. Joseph, J.; Mudduluru, G.; Antony, S.; Vashistha, S.; Ajitkumar, P. and Somasundaram, K. (2004) Oncogene, 23(37), 6304-6315.
196. Ailenberg, M. and Silverman, M. (2002) Biochem. Biophys. Res. Commun., 298(1), 110-115.
197. Kaneko, F.; Saito, H.; Saito, Y.; Wakabayashi, K.; Nakamoto, N.; Tada, S.; Suzuki, H.; Tsunematsu, S.; Kumegai, N. and Ishii, H. (2004) Int. J. Oncol., 24(4), 837-845.
198. Liu, L.T.; Chang, H.C.; Chiang, L.C. and Hung, W.C. (2003) Cancer Res., 63(12), 3069-3072.
199. Gagnon, J.; Shaker, S.; Primeau, M.; Hurtubise, A. and Momparler, R.L. (2003) Anticancer Drugs, 14(3), 193-202.
200. Polette, M. and Birembaut, P. (1998) Int. J. Biochem. Cell Biol., 30(11), 1195-1202.
201. Elaut, G.; Rogiers, V. and Vanhaecke, T. (2006) Curr. Pharm. Design, in press.
202. Dion, L.D.; Goldsmith, K.T.; Tang, D.C.; Engler, J.A.; Yoshida, M. and Garver, R.I.Jr. (1997) Virology, 231(2), 201-209.
203. Andrade-Rozental, A.F.; Rozental, R.; Hopperstad, M.G.; Wu, J.K.; Vrionis, F.D. and Spray, D.C. (2000) Brain Res. Brain Res. Rev., 32(1), 308-315.
204. Mesnil, M. and Yamasaki, H. (2000) Cancer Res., 60(15), 3989-3999.
205. Dilber, M.D.; Abedi, M.R.; Christensson, B.; Bjorkstrand, B.; Kidder, G.M.; Naus, C.C.; Cahrton, G. and Smith, C.I. (1997) Cancer Res., 57(8), 1523-1528.
206. Yamamoto, S.; Yamano, T.; Tanaka, M.; Hoon, D.S.; Takao, S.; Morishita, R.; Aikou, T. and Kaneda, Y. (2003) Cancer Gene Ther., 10(3), 179-186.
207. Armeanu, S.; Pathil, A.; Venturelli, S.; Mascagni, S.; Weiss, T.S.; Gottlicher, M.; Gottlicher, M.; Gregor, M.; Lauer, U.M. and Bitzer, M. (2005) J. Hepatol., 42(2), 210-218.
208. Herold, C.; Ganslmayer, M.; Ocker, M.; Hermann, M.; Geerts, A.; Hahn, E.G. and Schuppan, D. (2002) J. Hepatol., 36(2), 233-240.
209. Papeleu, P.; Loyer, P.; Vanhaecke, T.; Elaut, G.; Geerts, A.; Guguen-Guillouzo, C. and Rogiers, V. (2003) J. Hepatol., 39(3), 374-382.
210. Cong, Y.S. and Bacchetti, S. (2000) J. Biol. Chem., 275(46), 35665-35668.
211. Takakura, M.; Kyo, S.; Sowa, Y.; Wang, Z.; Yatabe, N.; Maida, Y.; Tanaka, M. and Inoue, M. (2001) Nucleic Acids Res., 29(14), 3006-3011.
212. Vinken, M.; Papeleu, P.; Vanhaecke, T. and Rogiers, V. (2006) J. Pharmacol. Exp. Ther., submitted.
213. Whetstine, J.R.; Ceron, J.; Ladd, B.; Dufourcq, P.; Reinke, V. and Shi, Y. (2005) Mol. Cell, 18(4), 483-490.
214. Camphausen, K.; Cerna, D.; Scott, T.; Sproull, M.; Burgan, W.E.; Cerra, M.A.; Fine, H. and Tofilon, J.J. (2005) Int. J. Cancer, 114(3), 380-386.
215. Jung, M.; Velena, A.; Chen, B.; Petukhov, P.A.; Kozikowski, A.P. and Dritschilo, A. (2005) Radiat. Res., 163(5), 488-493.
216. Munshi, A.; Kurland, J.F.; Nishikawa, T.; Tanaka, T.; Hobbs, M.L.; Tucker, S.L; Ismail, S.; Stevens, C. and Meyn, R.E. (2005) Clin. Cancer Res., 11(13), 4912-4922.
217. Rosato, R.R. and Grant, S. (2004) Expert. Opin. Investig. Drugs, 13(1), 21-38.
218. Shaker, S.; Bernstein, M. and Momparler, R.L. (2004) Oncol. Rep., 11(6), 1253-1256.
219. Riggs, M.G., Whittaker, R.G., Neumann, J.R. and Ingram, V.M. (1977) Nature, 268(5619), 462-464.
220. Boffa, L.C.; Vidali, G.; Mann, R.S. and Allfrey, V.G. (1978) J. Biol. Chem., 253(10), 3364-3366.
221. Gottlicher, M.; Minucci, S.; Zhu, P.; Kramer, O.H.; Schimpf, A.; Giavara, S.; Sleeman, J.P.; LoCocco, F.; Nervi, C., Pelicci, P.G. and Heinzel, T. (2001) EMBO J., 20(24), 6969-6978.
222. Yoshida, M.; Kijima, M.; Akita, M. and Beppu, T. (1990) J. Biol. Chem., 265(28), 17174-17179.
223. Richon, V.M.; Emiliani, S.; Verdin, E.; Webb, Y.; Breslow, R.; Rifkind, R.A. and Marks, P.A. (1998) Proc. Natl. Acad. Sci. U.S.A., 95(6), 3003-3007.
224. Suzuki, T.; Ando, T.; Tsuchiya, K.; Fukazawa, N.; Saito, A.; Mariko, Y.; Yamashita, T. and Nakanishi, O. (1999) J. Med. Chem., 42(15), 3001-3003.
225. Kraker, A.J.; Mizzen, C.A.; Hartl, B.G.; Miin, J.; Allis, C.D. and Merriman, R.L. (2003) Mol. Cancer Ther., 2(4), 401-408.
226. Frey, R.R.; Wada, C.K.; Garland, R.B.; Curtin, M.L.; Michaelides, M.R.; Li, J.; Pease, L.J.; Glaser, K.B.; Marcotte, P.A.; Bouska, J.J.; Murphy, S.S. and Davidsen, S.K. (2002) Bioorg. Med. Chem. Lett., 12(23), 3443-3447.
227. Glaser, K.B.; Li, J.; Pease, L.J.; Staver, M.J.; Marcotte, P.A.; Guo, J.; Frey, R.R.; Garland, R.B.; Heyman, H.R.; Wada, C.K.; Vasudevan, A.; Michaelides, M.R.; Davidsen, S.K. and Curtin, M.L. (2004) Biochem. Biophys. Res. Commun., 325(3), 683-690.
228. Kijima, M.; Yoshida, M.; Sugita, K.; Horinouchi, S. and Beppu T. (1993) J. Biol. Chem., 268(30), 22429-22435.
229. Brosch, G.; Ransom, R.; Lechner, T.; Walton, J.D. and Loidl, P. (1995) Plant Cell, 7(11), 1941-1950.
230. Nakajima, H.; Kim, Y.B.; Terano, H.; Yoshida, M. and Horinouchi, S. (1998) Exp. Cell Res., 241(1), 126-133.
231. Darkin-Rattray, S.J.; Gurnett, A.M.; Myers, R.W.; Dulski, P.M.; Crumley, T.M.; Allocco, J.J.; Cannova, C.; Meinke, P.T.; Colletti, S.L.; Bednarek, M.A.; Singh, S.B.; Goetz, M.A.; Dombrowski, A.W.; Polishook, J.D. and Schmatz, D.M. (1996) Proc. Natl. Acad. Sci. U.S.A., 93(23), 13143-13147.
232. Myzak, M.C.; Karplus, P.A.; Chung, F.L. and Dashwood, R.H. (2004) Cancer Res., 64(16), 5767-5774.
233. Kucerova, D.; Sloncova, E.; Tuhackova, Z.; Uhlirova, M.; Kos, M. and Sovova, V. (1999) Int. J. Mol. Med., 4(5), 541-544.
234. Fiorino, A.S. and Zvibel, I. (1996) Cell Biol. Int., 20(7), 489-499.