Sodium butyrate induces apoptosis in human hepatoma cells by a mitochondria/caspase pathway, associated with degradation of β-catenin, pRb and Bcl-XL

European Journal of Cancer

Volumn 40, Issue 9, 2004, Pages 1441-1452

  Emanuele, S ^a   D'Anneo, A ^a   Bellavia, G ^a   Vassallo, B ^a   Lauricella, M ^a   De Blasio, A ^a   Vento, R ^a   Tesoriere, G ^a  

^a Policlinico   (Italy)

Author keywords

Catenin; Apoptosis; pRb

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BETA CATENIN; BUTYRIC ACID; CASPASE; CASPASE 3; CASPASE 9; CYCLIN D; CYCLIN E; CYTOCHROME C; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL X; PROTEIN BCL XL; PROTEIN BCL XS; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CELL IMMORTALIZATION; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME RELEASE; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; BCL-X PROTEIN; BETA CATENIN; BLOTTING, WESTERN; BUTYRATES; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL LINE; CYCLIN E; CYCLINS; CYTOSKELETAL PROTEINS; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIALS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS;

EID: 2942605897     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2004.01.039     Document Type: Article

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