메뉴 건너뛰기




Volumn 286, Issue 6 55-6, 2004, Pages

The tight junction: A multifunctional complex

Author keywords

Function; Regulation; Tight junction structure

Indexed keywords

CELL ADHESION MOLECULE; CLAUDIN; MEMBRANE PROTEIN; OCCLUDIN;

EID: 2442619064     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00558.2003     Document Type: Review
Times cited : (1197)

References (167)
  • 1
    • 0037385217 scopus 로고    scopus 로고
    • Junctional protein MAGI-3 interacts with receptor tyrosine phosphatase β (RPTPβ) and tyrosine-phosphorylated proteins
    • Adamsky K, Arnold K, Sabanay H, and Peles E. Junctional protein MAGI-3 interacts with receptor tyrosine phosphatase β (RPTPβ) and tyrosine-phosphorylated proteins. J Cell Sci 116: 1279-1289, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 1279-1289
    • Adamsky, K.1    Arnold, K.2    Sabanay, H.3    Peles, E.4
  • 3
    • 0038780624 scopus 로고    scopus 로고
    • Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA
    • Amieva MR, Vogelmann R, Covacci A, Tompkins LS, Nelson WJ, and Falkow S. Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science 300: 1430-1434, 2003.
    • (2003) Science , vol.300 , pp. 1430-1434
    • Amieva, M.R.1    Vogelmann, R.2    Covacci, A.3    Tompkins, L.S.4    Nelson, W.J.5    Falkow, S.6
  • 4
    • 0035354574 scopus 로고    scopus 로고
    • Molecular structure of tight junctions and their role it epithelial transport
    • Anderson JM. Molecular structure of tight junctions and their role it epithelial transport. News Physiol Sci 16: 126-130, 2001.
    • (2001) News Physiol Sci , vol.16 , pp. 126-130
    • Anderson, J.M.1
  • 6
    • 0035914359 scopus 로고    scopus 로고
    • Protein kinase C regulates the phosphorylation and cellular localization of occludin
    • Andreeva AY, Krause E, Muller EC, Blasig IE, and Utepbergenov DI. Protein kinase C regulates the phosphorylation and cellular localization of occludin. J Biol Chem 276: 38480-38486, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 38480-38486
    • Andreeva, A.Y.1    Krause, E.2    Muller, E.C.3    Blasig, I.E.4    Utepbergenov, D.I.5
  • 7
    • 0035824527 scopus 로고    scopus 로고
    • Cloning of human junctional adhesion molecule 3 (JAM-3) and its identification as the JAM-2 counter-receptor
    • Arrate MP, Rodriguez JM, Tran TM, Brock TA, and Cunningham SA. Cloning of human junctional adhesion molecule 3 (JAM-3) and its identification as the JAM-2 counter-receptor. J Biol Chem 276: 45826-45832, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 45826-45832
    • Arrate, M.P.1    Rodriguez, J.M.2    Tran, T.M.3    Brock, T.A.4    Cunningham, S.A.5
  • 8
    • 0035951873 scopus 로고    scopus 로고
    • JAM-2 a novel immunoglobulin super-family molecule, expressed by endothelial and lymphatic cells
    • Aurand-Lions MA, Duncan L, Ballestrem C, and Imhof BA. JAM-2 a novel immunoglobulin super-family molecule, expressed by endothelial and lymphatic cells. J Biol Chem 276: 2733-2741, 2000.
    • (2000) J Biol Chem , vol.276 , pp. 2733-2741
    • Aurand-Lions, M.A.1    Duncan, L.2    Ballestrem, C.3    Imhof, B.A.4
  • 9
    • 0027414695 scopus 로고
    • Two classes of tight junctions are revealed by ZO-1 isoforms
    • Balda MS and Anderson JM. Two classes of tight junctions are revealed by ZO-1 isoforms. Am J Physiol Cell Physiol 264: C918-C924, 1993.
    • (1993) Am J Physiol Cell Physiol , vol.264
    • Balda, M.S.1    Anderson, J.M.2
  • 10
    • 0030590868 scopus 로고    scopus 로고
    • The SH3 domain of the tight junction protein ZO-1 binds to a serine protein kinase that phosphorylate: A region C-terminal to this domain
    • Balda MS, Anderson JM, and Matter K. The SH3 domain of the tight junction protein ZO-1 binds to a serine protein kinase that phosphorylate: a region C-terminal to this domain. FEBS Lett 399: 326-332, 1996.
    • (1996) FEBS Lett , vol.399 , pp. 326-332
    • Balda, M.S.1    Anderson, J.M.2    Matter, K.3
  • 11
    • 0037415643 scopus 로고    scopus 로고
    • The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density
    • Balda MS, Garrett MD, and Matter K. The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J Cell Biol 160: 423-432, 2003.
    • (2003) J Cell Biol , vol.160 , pp. 423-432
    • Balda, M.S.1    Garrett, M.D.2    Matter, K.3
  • 13
    • 0038021222 scopus 로고    scopus 로고
    • Epithelial cell adhesion and the regulation of gene expression
    • Balda MS and Matter K. Epithelial cell adhesion and the regulation of gene expression. Trends Cell Biol 13: 310-318, 2003.
    • (2003) Trends Cell Biol , vol.13 , pp. 310-318
    • Balda, M.S.1    Matter, K.2
  • 14
    • 0034595219 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression
    • Balda MS and Matter K. The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression. EMBO J 19: 2024-2033, 2000.
    • (2000) EMBO J , vol.19 , pp. 2024-2033
    • Balda, M.S.1    Matter, K.2
  • 15
    • 0029799520 scopus 로고    scopus 로고
    • Functional dissociation of paracellular permeability from electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant membrane protein o tight junctions
    • Balda MS, Whitney JA, Flores C, Gonzalez S, Cereijido M, and Matter K. Functional dissociation of paracellular permeability from electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant membrane protein o tight junctions. J Cell Biol 134: 1031-1049, 1996.
    • (1996) J Cell Biol , vol.134 , pp. 1031-1049
    • Balda, M.S.1    Whitney, J.A.2    Flores, C.3    Gonzalez, S.4    Cereijido, M.5    Matter, K.6
  • 18
    • 0039027605 scopus 로고    scopus 로고
    • Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin and occludin
    • Bazzoni G, Martinez-Estrada OM, Orsenigo F, Cordenonsi M, Citi S, and Dejana E. Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin and occludin. J Biol Chem 275: 20520-20526, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 20520-20526
    • Bazzoni, G.1    Martinez-Estrada, O.M.2    Orsenigo, F.3    Cordenonsi, M.4    Citi, S.5    Dejana, E.6
  • 19
    • 0029908483 scopus 로고    scopus 로고
    • The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-Large/ZO-1) domains and an alternatively spliced region
    • Beatch M, Jesaitis LA, Gallin WJ, Goodenough DA, and Stevenson BR. The tight junction protein ZO-2 contains three PDZ (PSD-95/Discs-Large/ZO-1) domains and an alternatively spliced region. J Biol Chem 271: 25723-25726, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 25723-25726
    • Beatch, M.1    Jesaitis, L.A.2    Gallin, W.J.3    Goodenough, D.A.4    Stevenson, B.R.5
  • 22
    • 0037369552 scopus 로고    scopus 로고
    • Intestinal epithelial responses to enteric pathogens: Effects on the tight junction barrier, ion transport and inflammation
    • Berkes J, Viswanathan VK, Savkovic SD, and Hecht G. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport and inflammation. Gut 52: 439-451, 2003.
    • (2003) Gut , vol.52 , pp. 439-451
    • Berkes, J.1    Viswanathan, V.K.2    Savkovic, S.D.3    Hecht, G.4
  • 23
    • 0029043658 scopus 로고
    • Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
    • Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, Stemmermann GN, and Nomura A. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 55: 2111-2115, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2111-2115
    • Blaser, M.J.1    Perez-Perez, G.I.2    Kleanthous, H.3    Cover, T.L.4    Peek, R.M.5    Chyou, P.H.6    Stemmermann, G.N.7    Nomura, A.8
  • 24
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E 47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA, Fraga MF, Esteller M, and Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci 116: 499-511, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 26
    • 0036226069 scopus 로고    scopus 로고
    • Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells
    • Chem YH, Lu Q, Goodenough DA, and Jeansonne B. Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Mol Biol Cell 13: 1227-1237 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 1227-1237
    • Chem, Y.H.1    Lu, Q.2    Goodenough, D.A.3    Jeansonne, B.4
  • 27
    • 0034099223 scopus 로고    scopus 로고
    • Restoration of tight junction structure and barrier function by down-regulation of the mitogen activated protein kinase pathway in Ras-transformed Madin-Darby canine kidney cells
    • Chem YH, Qun L, Schneeberger EE, and Goodenough DA. Restoration of tight junction structure and barrier function by down-regulation of the mitogen activated protein kinase pathway in Ras-transformed Madin-Darby canine kidney cells. Mol Biol Cell 11: 849-862, 2000.
    • (2000) Mol Biol Cell , vol.11 , pp. 849-862
    • Chem, Y.H.1    Qun, L.2    Schneeberger, E.E.3    Goodenough, D.A.4
  • 28
    • 80053187553 scopus 로고    scopus 로고
    • The cytoplasmic plaque proteins of the tight junction
    • edited by Anderson JM and Cereijido M. Boca Raton, FL: CRC
    • Citi S. The cytoplasmic plaque proteins of the tight junction. In: Tight Junctions (2nd ed.), edited by Anderson JM and Cereijido M. Boca Raton, FL: CRC, 2001, p. 231-264.
    • (2001) Tight Junctions (2nd Ed.) , pp. 231-264
    • Citi, S.1
  • 29
    • 0017855840 scopus 로고
    • Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens
    • Claude P. Morphological factors influencing transepithelial permeability: a model for the resistance of the zonula occludens. J Membr Biol 39: 219-232, 1978.
    • (1978) J Membr Biol , vol.39 , pp. 219-232
    • Claude, P.1
  • 30
    • 0015837872 scopus 로고
    • Fracture faces of zonulae occludentes from "tight" and "leaky" epithelia
    • Claude P and Goodenough DA. Fracture faces of zonulae occludentes from "tight" and "leaky" epithelia. J Cell Biol 58: 390-400, 1973.
    • (1973) J Cell Biol , vol.58 , pp. 390-400
    • Claude, P.1    Goodenough, D.A.2
  • 32
    • 0036085515 scopus 로고    scopus 로고
    • Claudins create charge-selective channels in the paracellular pathway between epithelial cells
    • Colegio OR, Van Itallie CM, McCrea HJ, Rahner C, and MAJ. Claudins create charge-selective channels in the paracellular pathway between epithelial cells. Am J Physiol Cell Physiol 283: C142-C147, 2002.
    • (2002) Am J Physiol Cell Physiol , vol.283
    • Colegio, O.R.1    Van Itallie, C.M.2    McCrea, H.J.3    Rahner, C.4
  • 33
    • 0038701734 scopus 로고    scopus 로고
    • Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture
    • Colegio OR, Van Itallie CM, Rahner C, and Anderson JM. Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture. Am J Physiol Cell Physiol 284: C1346-C1354, 2003.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Colegio, O.R.1    Van Itallie, C.M.2    Rahner, C.3    Anderson, J.M.4
  • 38
    • 0035898658 scopus 로고    scopus 로고
    • The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
    • Ebnet K, Suzuki A, Meyer zu Brickwedde MK, Ohno S, and Vestweber D. The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM). EMBO J 14: 3738-3748, 2001.
    • (2001) EMBO J , vol.14 , pp. 3738-3748
    • Ebnet, K.1    Suzuki, A.2    Meyer Zu Brickwedde, M.K.3    Ohno, S.4    Vestweber, D.5
  • 39
    • 0035195390 scopus 로고    scopus 로고
    • Claudin-2 is selectively expressed in proximal nephron in mouse kidney
    • Enck AH, Berger UV, and Yu A. Claudin-2 is selectively expressed in proximal nephron in mouse kidney. Am J Physiol Renal Physiol 281: F966-F974, 2001.
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Enck, A.H.1    Berger, U.V.2    Yu, A.3
  • 40
    • 0037222950 scopus 로고    scopus 로고
    • Cell polarity: Par 6, aPKC and cytoskeletal crosstalk
    • Etienne-Manneville S and Hall A. Cell polarity: Par6, aPKC and cytoskeletal crosstalk. Curr Opin Cell Biol 15: 67-72, 2003.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 67-72
    • Etienne-Manneville, S.1    Hall, A.2
  • 41
    • 0033560065 scopus 로고    scopus 로고
    • PDZ domains: Fundamental building blocks in the organization of protein complexes at the plasma membrane
    • Fanning AS and Anderson JM. PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. J Clin Invest 103: 767-772, 1999.
    • (1999) J Clin Invest , vol.103 , pp. 767-772
    • Fanning, A.S.1    Anderson, J.M.2
  • 42
    • 0032491391 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    • Fanning AS, Jameson BJ, Jesaitis LA, and Anderson JM. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 273: 29745-29753, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 29745-29753
    • Fanning, A.S.1    Jameson, B.J.2    Jesaitis, L.A.3    Anderson, J.M.4
  • 43
    • 0000752197 scopus 로고
    • Junctional complexes in various epithelia
    • Farquhar MG and Palade GE. Junctional complexes in various epithelia. J Cell Biol 17: 375-412, 1963.
    • (1963) J Cell Biol , vol.17 , pp. 375-412
    • Farquhar, M.G.1    Palade, G.E.2
  • 44
    • 0034617463 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein
    • Fujita K, Katahira J, Horiguchi Y, Sonoda N, Furuse M, and Tsukita S. Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein. FEBS Lett 476: 258-261, 2000.
    • (2000) FEBS Lett , vol.476 , pp. 258-261
    • Fujita, K.1    Katahira, J.2    Horiguchi, Y.3    Sonoda, N.4    Furuse, M.5    Tsukita, S.6
  • 46
    • 0030043414 scopus 로고    scopus 로고
    • Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
    • Furuse M, Fujimoto K, Sato N, Hirase T, Tsukita S, and Tsukita S. Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J Cell Sci 109: 429-435, 1996.
    • (1996) J Cell Sci , vol.109 , pp. 429-435
    • Furuse, M.1    Fujimoto, K.2    Sato, N.3    Hirase, T.4    Tsukita, S.5    Tsukita, S.6
  • 47
    • 0032577975 scopus 로고    scopus 로고
    • Claudin 1 and 2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M, Fujita K, Fujimoto K, and Tsukita S. Claudin 1 and 2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141: 1539-1550, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Fujimoto, K.3    Tsukita, S.4
  • 48
    • 0035897412 scopus 로고    scopus 로고
    • Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells
    • Furuse M, Furuse K, Sasaki H, and Tsukita S. Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J Cell Biol 153: 263-272, 2001.
    • (2001) J Cell Biol , vol.153 , pp. 263-272
    • Furuse, M.1    Furuse, K.2    Sasaki, H.3    Tsukita, S.4
  • 49
    • 0037128938 scopus 로고    scopus 로고
    • Claudin-based tight junctions are crucial for the mammalian epidermal barrier: A lesson from claudin-1 deficient mice
    • Furuse M, Hata M, Furuse K, Yoshida Y, Haratake A, Sugitani Y, Noda T, Kubo A, and Tsukita S. Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1 deficient mice. J Cell Biol 156: 1099-1111, 2002.
    • (2002) J Cell Biol , vol.156 , pp. 1099-1111
    • Furuse, M.1    Hata, M.2    Furuse, K.3    Yoshida, Y.4    Haratake, A.5    Sugitani, Y.6    Noda, T.7    Kubo, A.8    Tsukita, S.9
  • 51
    • 0032547833 scopus 로고    scopus 로고
    • A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts
    • Furuse M, Sasaki H, Fujimoto K, and Tsukita S. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 143: 391-401, 1998.
    • (1998) J Cell Biol , vol.143 , pp. 391-401
    • Furuse, M.1    Sasaki, H.2    Fujimoto, K.3    Tsukita, S.4
  • 52
    • 0033571047 scopus 로고    scopus 로고
    • Manner of interaction of heterogeneous claudin species within and between tight junction strands
    • Furuse M, Sasaki H, and Tsukita S. Manner of interaction of heterogeneous claudin species within and between tight junction strands. J Cell Biol 147: 891-903, 1999.
    • (1999) J Cell Biol , vol.147 , pp. 891-903
    • Furuse, M.1    Sasaki, H.2    Tsukita, S.3
  • 53
    • 13144252170 scopus 로고    scopus 로고
    • The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein
    • Giepmans BN and Moolenaar WH. The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr Biol 8: 931-934, 1998.
    • (1998) Curr Biol , vol.8 , pp. 931-934
    • Giepmans, B.N.1    Moolenaar, W.H.2
  • 54
    • 0034597533 scopus 로고    scopus 로고
    • Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF and high-risk papillomavirus E 6 oncoproteins
    • Glaunsinger BA, Lee SS, Thomas M, Banks L, and Javier R. Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF and high-risk papillomavirus E6 oncoproteins. Oncogene 19: 5270-5280, 2000.
    • (2000) Oncogene , vol.19 , pp. 5270-5280
    • Glaunsinger, B.A.1    Lee, S.S.2    Thomas, M.3    Banks, L.4    Javier, R.5
  • 55
    • 0035887255 scopus 로고    scopus 로고
    • Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2
    • Glaunsinger BA, Weiss RS, Lee SS, and Javier R. Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2. EMBO J 20: 5578-5586, 2001.
    • (2001) EMBO J , vol.20 , pp. 5578-5586
    • Glaunsinger, B.A.1    Weiss, R.S.2    Lee, S.S.3    Javier, R.4
  • 56
    • 0029744106 scopus 로고    scopus 로고
    • The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts
    • Gottardi CJ, Arpin M, Fanning AS, and Louvard D. The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. Proc Natl Acad Sci USA 93: 10779-10784, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10779-10784
    • Gottardi, C.J.1    Arpin, M.2    Fanning, A.S.3    Louvard, D.4
  • 58
    • 0032577562 scopus 로고    scopus 로고
    • Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells
    • Grindstaff KK, Yeaman C, Anandasabapathy N, Hsu SC, Rodri-guez-Boulan E, Scheller RH, and Nelson WJ. Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. Cell 93: 731-740, 1998.
    • (1998) Cell , vol.93 , pp. 731-740
    • Grindstaff, K.K.1    Yeaman, C.2    Anandasabapathy, N.3    Hsu, S.C.4    Rodri-Guez-Boulan, E.5    Scheller, R.H.6    Nelson, W.J.7
  • 59
    • 0026345292 scopus 로고
    • Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1
    • Gumbiner B, Lowenkopf T, and Apatira D. Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci USA 88: 3460-3464, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3460-3464
    • Gumbiner, B.1    Lowenkopf, T.2    Apatira, D.3
  • 60
    • 0022569860 scopus 로고
    • A functional assay for proteins involved in establishing an epithelial occluding barrier: Identification of a uvomorulin-like polypeptide
    • Gumbiner B and Simons K. A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide. J Cell Biol 102: 457-468, 1986.
    • (1986) J Cell Biol , vol.102 , pp. 457-468
    • Gumbiner, B.1    Simons, K.2
  • 61
    • 0037016668 scopus 로고    scopus 로고
    • Multi-PD2 domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule
    • Hamazaki Y, Itoh M, Sasaki H, Furuse M, and Tsukita S. Multi-PD2 domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem 277: 455-461, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 455-461
    • Hamazaki, Y.1    Itoh, M.2    Sasaki, H.3    Furuse, M.4    Tsukita, S.5
  • 62
    • 0026762963 scopus 로고
    • Mapping of functional regions of Clostridium perfringens type A enterotoxin
    • Hanna PC, Wieckowski EH, Mietzner TA, and McClane BA. Mapping of functional regions of Clostridium perfringens type A enterotoxin. Infect Immun 60: 2110-2114, 1992.
    • (1992) Infect Immun , vol.60 , pp. 2110-2114
    • Hanna, P.C.1    Wieckowski, E.H.2    Mietzner, T.A.3    McClane, B.A.4
  • 63
    • 0033597791 scopus 로고    scopus 로고
    • Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cells
    • Hasegawa H, Fujita H, Katoh H, Aoki J, Nakamura K, Ichikawa A, and Negishi M. Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cells. J Biol Chem 274: 20982-20988, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 20982-20988
    • Hasegawa, H.1    Fujita, H.2    Katoh, H.3    Aoki, J.4    Nakamura, K.5    Ichikawa, A.6    Negishi, M.7
  • 64
    • 0032489875 scopus 로고    scopus 로고
    • ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
    • Haskins J, Lijie G, Wittchen ES, Hibbard J, and Stevenson BR. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol 141: 199-208, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 199-208
    • Haskins, J.1    Lijie, G.2    Wittchen, E.S.3    Hibbard, J.4    Stevenson, B.R.5
  • 65
    • 0037641234 scopus 로고    scopus 로고
    • JAM-4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1
    • Hirabayashi S, Tajima M, Yao I, Nishimura W, Mori H, and Hata Y. JAM-4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol 23: 4267-4282, 2003.
    • (2003) Mol Cell Biol , vol.23 , pp. 4267-4282
    • Hirabayashi, S.1    Tajima, M.2    Yao, I.3    Nishimura, W.4    Mori, H.5    Hata, Y.6
  • 66
    • 0035971219 scopus 로고    scopus 로고
    • Regulation of tight junction permeability and occludin phosphorylation by RhoA-p160ROCK-dependent and -independent mechanisms
    • Hirase T, Kawashima S, Wong EYM, Ueyama T, Rikitake Y, Tsukita S, Yokoyama M, and Staddon JM. Regulation of tight junction permeability and occludin phosphorylation by RhoA-p160ROCK-dependent and -independent mechanisms. J Biol Chem 276: 10423-10431, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 10423-10431
    • Hirase, T.1    Kawashima, S.2    Wong, E.Y.M.3    Ueyama, T.4    Rikitake, Y.5    Tsukita, S.6    Yokoyama, M.7    Staddon, J.M.8
  • 69
    • 0036000009 scopus 로고    scopus 로고
    • Symplekin, a constitutive protein of karyo- and cytoplasmic particles involved in mRNA biogenesis in Xenopus laevis oocytes
    • Hofmann I, Schnoelzer M, Kaufmann I, and Franke WW. Symplekin, a constitutive protein of karyo- and cytoplasmic particles involved in mRNA biogenesis in Xenopus laevis oocytes. Mol Biol Cell 13: 1665-1676, 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 1665-1676
    • Hofmann, I.1    Schnoelzer, M.2    Kaufmann, I.3    Franke, W.W.4
  • 70
    • 0026603087 scopus 로고
    • Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types
    • Howarth AG, Hughes MR, and Stevenson BR. Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types. Am J Physiol Cell Physiol 262: C461-C469, 1992.
    • (1992) Am J Physiol Cell Physiol , vol.262
    • Howarth, A.G.1    Hughes, M.R.2    Stevenson, B.R.3
  • 71
    • 0037319350 scopus 로고    scopus 로고
    • Direct interaction of two polarity complexes implicated in epithelial tight junction assembly
    • Hurd TW, Gao L, Roh MH, Macara IG, and Margolis B. Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nat Cell Biol 5: 137-142, 2003.
    • (2003) Nat Cell Biol , vol.5 , pp. 137-142
    • Hurd, T.W.1    Gao, L.2    Roh, M.H.3    Macara, I.G.4    Margolis, B.5
  • 72
    • 0038106228 scopus 로고    scopus 로고
    • Regulation of tight junctions during epithelium-mesenchyme transition: Direct repression of the gene expression of claudins/occludin by Snail
    • Ikenouchi J, Matsuda M, Furuse M, and Tsukita S. Regulation of tight junctions during epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci 116: 1959-1967, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 1959-1967
    • Ikenouchi, J.1    Matsuda, M.2    Furuse, M.3    Tsukita, S.4
  • 73
    • 0033552629 scopus 로고    scopus 로고
    • Direct binding of three tight j unction-associated MAGUKs, ZO-1, ZO-2 and ZO-3, with the COOH termini of claudins
    • Itoh M, Furuse M, Morita K, Kubota K, Saitou M, and Tsukita S. Direct binding of three tight j unction-associated MAGUKs, ZO-1, ZO-2 and ZO-3, with the COOH termini of claudins. J Cell Biol 147: 1351-1363, 1999.
    • (1999) J Cell Biol , vol.147 , pp. 1351-1363
    • Itoh, M.1    Furuse, M.2    Morita, K.3    Kubota, K.4    Saitou, M.5    Tsukita, S.6
  • 74
    • 0033605347 scopus 로고    scopus 로고
    • Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and α catenin
    • Itoh M, Kazumasa M, and Tsukita S. Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and α catenin. J Biol Chem 274: 5981-5986, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 5981-5986
    • Itoh, M.1    Kazumasa, M.2    Tsukita, S.3
  • 75
    • 0030748548 scopus 로고    scopus 로고
    • Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments
    • Itoh M, Nagafuchi A, Moroi S, and Tsukita S. Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol 138: 181-192, 1997.
    • (1997) J Cell Biol , vol.138 , pp. 181-192
    • Itoh, M.1    Nagafuchi, A.2    Moroi, S.3    Tsukita, S.4
  • 76
    • 0027300689 scopus 로고
    • The 220-kD protein colocalizing with cadherins in nonepithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy
    • Itoh M, Nagafuchi A, Yonemura S, Kitani-Yasuda T, Tsukita S, and Tsukita S. The 220-kD protein colocalizing with cadherins in nonepithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy. J Cell Biol 121: 491-502, 1993.
    • (1993) J Cell Biol , vol.121 , pp. 491-502
    • Itoh, M.1    Nagafuchi, A.2    Yonemura, S.3    Kitani-Yasuda, T.4    Tsukita, S.5    Tsukita, S.6
  • 77
    • 0035817623 scopus 로고    scopus 로고
    • Junctional adhesion molecule (JAM) binds to PAR-3: A possible mechanism for the recruitment of PAR-3 to tight junctions
    • Itoh M, Sasaki H, Furuse M, Ozaki H, Kita T, and Tsukita S. Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions. J Cell Biol 154: 491-497, 2001.
    • (2001) J Cell Biol , vol.154 , pp. 491-497
    • Itoh, M.1    Sasaki, H.2    Furuse, M.3    Ozaki, H.4    Kita, T.5    Tsukita, S.6
  • 78
    • 0032487494 scopus 로고    scopus 로고
    • An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
    • Izumi Y, Hirose T, Tamai Y, Hirai S, Nagashima Y, Fujimoto T, Tabuse Y, Kemphues KJ, and Ohno S. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J Cell Biol 143: 95-106, 1998.
    • (1998) J Cell Biol , vol.143 , pp. 95-106
    • Izumi, Y.1    Hirose, T.2    Tamai, Y.3    Hirai, S.4    Nagashima, Y.5    Fujimoto, T.6    Tabuse, Y.7    Kemphues, K.J.8    Ohno, S.9
  • 79
    • 1542778870 scopus 로고    scopus 로고
    • Claudin-8 interacts with multi-PDZ domain protein 1 (MUPP1) and reduces paracellular conductance in epithelial cells
    • Jeansonne B, Lu Q, Goodenough DA, and Chem YH. Claudin-8 interacts with multi-PDZ domain protein 1 (MUPP1) and reduces paracellular conductance in epithelial cells. Cell Mol Biol (Noisy-le-grand) 49: 13-21, 2003.
    • (2003) Cell Mol Biol (Noisy-le-grand) , vol.49 , pp. 13-21
    • Jeansonne, B.1    Lu, Q.2    Goodenough, D.A.3    Chem, Y.H.4
  • 80
    • 0028287035 scopus 로고
    • Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein
    • Jesaitis LA and Goodenough DA. Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J Cell Biol 124: 949-961, 1994.
    • (1994) J Cell Biol , vol.124 , pp. 949-961
    • Jesaitis, L.A.1    Goodenough, D.A.2
  • 81
    • 0034253536 scopus 로고    scopus 로고
    • The cell-polarity protein Par 6 links Par3 and atypical protein kinase C to Cdc42
    • Joberty G, Petersen C, Gao L, and Macara IG. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol 2: 531-539, 2000.
    • (2000) Nat Cell Biol , vol.2 , pp. 531-539
    • Joberty, G.1    Petersen, C.2    Gao, L.3    Macara, I.G.4
  • 82
    • 0032514134 scopus 로고    scopus 로고
    • Structural and functional regulation of tight junctions by RhoA and Rac 1 small GTPases
    • Jou TS, Schneeberger EE, and Nelson WJ. Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol 142: 101-115, 1998.
    • (1998) J Cell Biol , vol.142 , pp. 101-115
    • Jou, T.S.1    Schneeberger, E.E.2    Nelson, W.J.3
  • 83
    • 0029840160 scopus 로고    scopus 로고
    • Symplekin, a novel type of tight junction plaque protein
    • Keon BH, Schafer S, Kuhn C, Grund C, and Franke WW. Symplekin, a novel type of tight junction plaque protein. J Cell Biol 134: 1003-1018, 1996.
    • (1996) J Cell Biol , vol.134 , pp. 1003-1018
    • Keon, B.H.1    Schafer, S.2    Kuhn, C.3    Grund, C.4    Franke, W.W.5
  • 84
    • 0036208599 scopus 로고    scopus 로고
    • Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments
    • Kiuchi-Saishin Y, Gotoh S, Furuse M, Takasuga A, Tano Y, and Tsukita S. Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments. J Am Soc Nephrol 13: 875-886, 2002.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 875-886
    • Kiuchi-Saishin, Y.1    Gotoh, S.2    Furuse, M.3    Takasuga, A.4    Tano, Y.5    Tsukita, S.6
  • 87
    • 0028953668 scopus 로고
    • Increase Tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes
    • Kurihara H, Anderson JM, and Farquhar MG. Increase Tyr phosphorylation of ZO-1 during modification of tight junctions between glomerular foot processes. Am J Physiol Renal Fluid Electrolyte Physiol 268: F514-F524, 1995.
    • (1995) Am J Physiol Renal Fluid Electrolyte Physiol , vol.268
    • Kurihara, H.1    Anderson, J.M.2    Farquhar, M.G.3
  • 88
    • 0033815457 scopus 로고    scopus 로고
    • Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF and high risk papillomavirus type 18 E6 oncoproteins
    • Lee SS, Glaunsinger BA, Mantovani F, Banks L, and Javier RT. Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF and high risk papillomavirus type 18 E6 oncoproteins. J Virol 74: 9680-9693, 2000.
    • (2000) J Virol , vol.74 , pp. 9680-9693
    • Lee, S.S.1    Glaunsinger, B.A.2    Mantovani, F.3    Banks, L.4    Javier, R.T.5
  • 89
    • 0034695923 scopus 로고    scopus 로고
    • Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin
    • Li D and Mrsny RJ. Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin. J Cell Biol 148: 791-800, 2000.
    • (2000) J Cell Biol , vol.148 , pp. 791-800
    • Li, D.1    Mrsny, R.J.2
  • 90
    • 0000202186 scopus 로고    scopus 로고
    • A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Racl and aPKC signalling and cell polarity
    • Lin D, Edwards AS, Fawcett JP, Mbamalu G, Scott JD, and Pawson T. A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Racl and aPKC signalling and cell polarity. Nat Cell Biol 2: 540-547, 2000.
    • (2000) Nat Cell Biol , vol.2 , pp. 540-547
    • Lin, D.1    Edwards, A.S.2    Fawcett, J.P.3    Mbamalu, G.4    Scott, J.D.5    Pawson, T.6
  • 91
    • 0034122209 scopus 로고    scopus 로고
    • Expression from the human occludin promoter is affected by tumor necrosis factor ct a and interferon γ
    • Mankertz J, Tavalali S, Schmitz H, Mankertz A, Riecken EO, Fromm M, and Schulzke JD. Expression from the human occludin promoter is affected by tumor necrosis factor ct a and interferon γ. J Cell Sci 113: 2085-2090, 2000.
    • (2000) J Cell Sci , vol.113 , pp. 2085-2090
    • Mankertz, J.1    Tavalali, S.2    Schmitz, H.3    Mankertz, A.4    Riecken, E.O.5    Fromm, M.6    Schulzke, J.D.7
  • 92
    • 0035937810 scopus 로고    scopus 로고
    • Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial Caco-2 cells
    • Martinez-Estrada OM, Villa A, Breviario F, Orsenigro F, Dejana E, and Bazzoni G. Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial Caco-2 cells. J Biol Chem 276: 9291-9296, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 9291-9296
    • Martinez-Estrada, O.M.1    Villa, A.2    Breviario, F.3    Orsenigro, F.4    Dejana, E.5    Bazzoni, G.6
  • 95
    • 0037336565 scopus 로고    scopus 로고
    • Signalling to and from tight junctions
    • Matter K and Balda MS. Signalling to and from tight junctions. Nat Mol Cell Biol 4: 225-236, 2003.
    • (2003) Nat Mol Cell Biol , vol.4 , pp. 225-236
    • Matter, K.1    Balda, M.S.2
  • 98
    • 0023871271 scopus 로고
    • Divalent cation involvement in the action of Clostridium perfringens type A enterotoxin
    • McClane BA, Wnek AP, Hulkower KI, and Hanna PC. Divalent cation involvement in the action of Clostridium perfringens type A enterotoxin. J Biol Chem 263: 2423-2435, 1988.
    • (1988) J Biol Chem , vol.263 , pp. 2423-2435
    • McClane, B.A.1    Wnek, A.P.2    Hulkower, K.I.3    Hanna, P.C.4
  • 99
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor H and Parker PJ. The extended protein kinase C superfamily. Biochem J 332: 281-292, 1998.
    • (1998) Biochem J , vol.332 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 100
    • 0037067660 scopus 로고    scopus 로고
    • Zonula occludens-1 is a scaffolding protein for signaling molecules
    • Meyer TN, Schwesinger C, and Denker BM. Zonula occludens-1 is a scaffolding protein for signaling molecules. J Biol Chem 277: 24855-24858, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 24855-24858
    • Meyer, T.N.1    Schwesinger, C.2    Denker, B.M.3
  • 101
    • 0031944250 scopus 로고    scopus 로고
    • Molecular architecture of tight junctions
    • Mitic LL and Anderson JM. Molecular architecture of tight junctions. Annu Rev Physiol 60: 121-142, 1998.
    • (1998) Annu Rev Physiol , vol.60 , pp. 121-142
    • Mitic, L.L.1    Anderson, J.M.2
  • 102
    • 0037304386 scopus 로고    scopus 로고
    • Expression, solubilization and biochemical characterization of the tight junction transmembrane protein claudin-4
    • Mitic LL, Unger VM, and Anderson JM. Expression, solubilization and biochemical characterization of the tight junction transmembrane protein claudin-4. Protein Sci 12: 218-227, 2003.
    • (2003) Protein Sci , vol.12 , pp. 218-227
    • Mitic, L.L.1    Unger, V.M.2    Anderson, J.M.3
  • 103
    • 0002899825 scopus 로고    scopus 로고
    • Occludin and claudins: Transmembrane proteins of the tight junction
    • edited by Cereijido M and Anderson JM. Boca Raton, FL: CRC
    • Mitic LL and Van Itallie CM. Occludin and claudins: transmembrane proteins of the tight junction. In: Tight Junctions (2nd ed.), edited by Cereijido M and Anderson JM. Boca Raton, FL: CRC, 2001, p. 213-230.
    • (2001) Tight Junctions (2nd Ed.) , pp. 213-230
    • Mitic, L.L.1    Van Itallie, C.M.2
  • 104
    • 0034584636 scopus 로고    scopus 로고
    • Involvement of claudin-1 in the β-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers
    • Miwa N, Furuse M, Tsukita S, Niikawa N, Nakamura Y, and Furukawa Y. Involvement of claudin-1 in the β-catenin/Tcf signaling pathway and its frequent upregulation in human colorectal cancers. Oncol Res 12: 469-476, 2000.
    • (2000) Oncol Res , vol.12 , pp. 469-476
    • Miwa, N.1    Furuse, M.2    Tsukita, S.3    Niikawa, N.4    Nakamura, Y.5    Furukawa, Y.6
  • 105
    • 0042232080 scopus 로고    scopus 로고
    • Self-association of PAR-3-mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions
    • Mizuno K, Suzuki A, Hirose T, Kitamura K, Kutsuzawa K, Futaki M, Amano Y, and Ohno S. Self-association of PAR-3-mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions. J Biol Chem 278: 31240-31250, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 31240-31250
    • Mizuno, K.1    Suzuki, A.2    Hirose, T.3    Kitamura, K.4    Kutsuzawa, K.5    Futaki, M.6    Amano, Y.7    Ohno, S.8
  • 106
    • 0033996784 scopus 로고    scopus 로고
    • Occludin IB, a variant of the tight junction protein
    • Muresan Z, Paul DL, and Goodenough DA. Occludin IB, a variant of the tight junction protein. Mol Biol Cell 11: 627-634, 2000.
    • (2000) Mol Biol Cell , vol.11 , pp. 627-634
    • Muresan, Z.1    Paul, D.L.2    Goodenough, D.A.3
  • 107
    • 0036156362 scopus 로고    scopus 로고
    • Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells
    • Musch A, Cohen D, Yeaman C, Nelson WJ, Rodriguez-Boulan E, and Brennwald PJ. Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells. Mol Biol Cell 13: 158-168, 2002.
    • (2002) Mol Biol Cell , vol.13 , pp. 158-168
    • Musch, A.1    Cohen, D.2    Yeaman, C.3    Nelson, W.J.4    Rodriguez-Boulan, E.5    Brennwald, P.J.6
  • 108
    • 12944262412 scopus 로고    scopus 로고
    • huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions
    • Nakamura T, Blechman J, Tada S, Rozovskaia T, Itoyama T, Bullrich F, Mazo A, Croce CM, Geiger B, and Canaani E. huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions. Proc Natl Acad Sci USA 97: 7284-7289, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7284-7289
    • Nakamura, T.1    Blechman, J.2    Tada, S.3    Rozovskaia, T.4    Itoyama, T.5    Bullrich, F.6    Mazo, A.7    Croce, C.M.8    Geiger, B.9    Canaani, E.10
  • 110
    • 0037009005 scopus 로고    scopus 로고
    • Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex
    • Nunbhakdi-Craig V, Machleidt T, Ogris E, Bellotto D, White CL, and Sontag E. Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex. J Cell Biol 158: 967-978, 2002.
    • (2002) J Cell Biol , vol.158 , pp. 967-978
    • Nunbhakdi-Craig, V.1    Machleidt, T.2    Ogris, E.3    Bellotto, D.4    White, C.L.5    Sontag, E.6
  • 111
    • 0034703027 scopus 로고    scopus 로고
    • The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction
    • Nusrat A, Chem JA, Foley CS, Liang TW, Toth J, Cromwell M, Quant C, and Mrsny RJ. The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction. J Biol Chem 275: 29816-29822, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 29816-29822
    • Nusrat, A.1    Chem, J.A.2    Foley, C.S.3    Liang, T.W.4    Toth, J.5    Cromwell, M.6    Quant, C.7    Mrsny, R.J.8
  • 112
    • 17344379177 scopus 로고    scopus 로고
    • Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion
    • Odenbreit S, Puls J, Sedlmaier B, Gerland E, Fischer W, and Haas R. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 287: 1497-1500, 2000.
    • (2000) Science , vol.287 , pp. 1497-1500
    • Odenbreit, S.1    Puls, J.2    Sedlmaier, B.3    Gerland, E.4    Fischer, W.5    Haas, R.6
  • 113
    • 0034705379 scopus 로고    scopus 로고
    • Vascular-endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells
    • Palmeri D, van Zante A, Huang CC, Hemmerich S, and Rosen SD. Vascular-endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J Biol Chem 275: 19139-19145, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 19139-19145
    • Palmeri, D.1    Van Zante, A.2    Huang, C.C.3    Hemmerich, S.4    Rosen, S.D.5
  • 114
    • 0035920152 scopus 로고    scopus 로고
    • A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions
    • Perez-Moreno MA, Locascio a Rodrigo I, Dhondt G, Portillo F, Nieto MA, and Cano A. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J Biol Chem 2001: 27424-27431, 2001.
    • (2001) J Biol Chem , vol.2001 , pp. 27424-27431
    • Perez-Moreno, M.A.1    Locascio, A.2    Rodrigo, I.3    Dhondt, G.4    Portillo, F.5    Nieto, M.A.6    Cano, A.7
  • 117
    • 0040782187 scopus 로고    scopus 로고
    • The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney I cells
    • Reichert M, Mueller T, and Hunziker W. The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney I cells. J Biol Chem 275: 9492-9500, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 9492-9500
    • Reichert, M.1    Mueller, T.2    Hunziker, W.3
  • 118
    • 0037178864 scopus 로고    scopus 로고
    • The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions
    • Roh MH, Liu CJ, Laurinec S, and Margolis B. The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions. J Biol Chem 277: 27501-27509, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 27501-27509
    • Roh, M.H.1    Liu, C.J.2    Laurinec, S.3    Margolis, B.4
  • 120
    • 0042466237 scopus 로고    scopus 로고
    • Composition and function of PDZ protein complexes during cell polarization
    • Roh MH and Margolis B. Composition and function of PDZ protein complexes during cell polarization. Am J Physiol Renal Physiol 285: F377-F387, 2003.
    • (2003) Am J Physiol Renal Physiol , vol.285
    • Roh, M.H.1    Margolis, B.2
  • 122
    • 0032550221 scopus 로고    scopus 로고
    • Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
    • Saitou M, Fujimoto K, Doi Y, Itoh M, Fujimoto T, Furuse M, Takano H, Noda T, and Tsukita S. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol 141: 397-408, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 397-408
    • Saitou, M.1    Fujimoto, K.2    Doi, Y.3    Itoh, M.4    Fujimoto, T.5    Furuse, M.6    Takano, H.7    Noda, T.8    Tsukita, S.9
  • 124
    • 0037077248 scopus 로고    scopus 로고
    • Cloning of the human claudin-2 5′-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1α
    • Sakaguchi T, Gu X, Golden HM, Suh ER, Rhoads DB, and Reinecker HC. Cloning of the human claudin-2 5′-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1α. J Biol Chem 277: 21361-21370, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 21361-21370
    • Sakaguchi, T.1    Gu, X.2    Golden, H.M.3    Suh, E.R.4    Rhoads, D.B.5    Reinecker, H.C.6
  • 125
    • 0030982357 scopus 로고    scopus 로고
    • Possible involvement of phosphorylation of occludin in tight junction formation
    • Sakakibara A, Furuse M, Saitou M, Ando-Akatsuka Y, and Tsukita Y. Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol 137: 1393-1401, 1997.
    • (1997) J Cell Biol , vol.137 , pp. 1393-1401
    • Sakakibara, A.1    Furuse, M.2    Saitou, M.3    Ando-Akatsuka, Y.4    Tsukita, Y.5
  • 127
    • 0019520573 scopus 로고
    • Segmental differentiation of endothelial intercellular junctions in intra-acinar arteries and veins of the rat lung
    • Schneeberger EE. Segmental differentiation of endothelial intercellular junctions in intra-acinar arteries and veins of the rat lung. Circ Res 49: 1102-1111, 1981.
    • (1981) Circ Res , vol.49 , pp. 1102-1111
    • Schneeberger, E.E.1
  • 128
    • 0017116756 scopus 로고
    • Substructure of intercellular junctions in freeze-fractured alveolar-capillary membranes of mouse lung
    • Schneeberger EE and Karnovsky MJ. Substructure of intercellular junctions in freeze-fractured alveolar-capillary membranes of mouse lung. Circ Res 38: 404-411, 1976.
    • (1976) Circ Res , vol.38 , pp. 404-411
    • Schneeberger, E.E.1    Karnovsky, M.J.2
  • 129
    • 0024202115 scopus 로고
    • Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cells
    • Siliciano JD and Goodenough DA. Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cells. J Cell Biol 107: 2389-2399, 1988.
    • (1988) J Cell Biol , vol.107 , pp. 2389-2399
    • Siliciano, J.D.1    Goodenough, D.A.2
  • 131
    • 0033523773 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier
    • Sonoda N, Furuse M, Sasaki H, Yonemura S, Katahira J, Horiguchi Y, and Tsukita S. Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: evidence for direct involvement of claudins in tight junction barrier. J Cell Biol 147: 195-204, 1999.
    • (1999) J Cell Biol , vol.147 , pp. 195-204
    • Sonoda, N.1    Furuse, M.2    Sasaki, H.3    Yonemura, S.4    Katahira, J.5    Horiguchi, Y.6    Tsukita, S.7
  • 132
    • 0015846194 scopus 로고
    • Further observations on the fine structure of freeze-cleaved tight junctions
    • Staehelin LA. Further observations on the fine structure of freeze-cleaved tight junctions. J Cell Sci 13: 763-786, 1973.
    • (1973) J Cell Sci , vol.13 , pp. 763-786
    • Staehelin, L.A.1
  • 133
  • 134
    • 0024211161 scopus 로고
    • Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial electrical resistance
    • Stevenson BR, Anderson JM, Goodenough DA, and Mooseker MS. Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial electrical resistance. J Cell Biol 107: 2401-2408, 1988.
    • (1988) J Cell Biol , vol.107 , pp. 2401-2408
    • Stevenson, B.R.1    Anderson, J.M.2    Goodenough, D.A.3    Mooseker, M.S.4
  • 135
    • 0032440448 scopus 로고    scopus 로고
    • The tight junction: Morphology to molecules
    • Stevenson BR and Keon BH. The tight junction: morphology to molecules. Annu Rev Cell Dev Biol 14: 89-109, 1998.
    • (1998) Annu Rev Cell Dev Biol , vol.14 , pp. 89-109
    • Stevenson, B.R.1    Keon, B.H.2
  • 136
    • 0023030826 scopus 로고
    • Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
    • Stevenson BR, Siliciano JD, Mooseker JD, and Goodenough DA. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol 103: 755-766, 1986.
    • (1986) J Cell Biol , vol.103 , pp. 755-766
    • Stevenson, B.R.1    Siliciano, J.D.2    Mooseker, J.D.3    Goodenough, D.A.4
  • 137
    • 0037106581 scopus 로고    scopus 로고
    • aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization
    • Suzuki A, Ishiyama C, Hashiba K, Shimizu M, Ebnet K, and Ohno S. aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization. J Cell Sci 115: 3565-3573, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 3565-3573
    • Suzuki, A.1    Ishiyama, C.2    Hashiba, K.3    Shimizu, M.4    Ebnet, K.5    Ohno, S.6
  • 138
    • 0033984159 scopus 로고    scopus 로고
    • Complex protein interactions within the human polyadenylation machinery identify a novel component
    • Takagaki Y and Manley JL. Complex protein interactions within the human polyadenylation machinery identify a novel component. Mol Cell Biol 20: 1515-1525, 2000.
    • (2000) Mol Cell Biol , vol.20 , pp. 1515-1525
    • Takagaki, Y.1    Manley, J.L.2
  • 139
    • 0037342777 scopus 로고    scopus 로고
    • Paracellular ion channel at the tight junction
    • Tang VW and Goodenough DA. Paracellular ion channel at the tight junction. Biophys J 84: 1660-1673, 2003.
    • (2003) Biophys J , vol.84 , pp. 1660-1673
    • Tang, V.W.1    Goodenough, D.A.2
  • 141
    • 0037462794 scopus 로고    scopus 로고
    • The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B
    • Traweger A, Fuchs R, Krizbai IA, Weiger TM, Bauer HC, and Bauer H. The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B. J Biol Chem 278: 2692-2700, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 2692-2700
    • Traweger, A.1    Fuchs, R.2    Krizbai, I.A.3    Weiger, T.M.4    Bauer, H.C.5    Bauer, H.6
  • 142
    • 0033004247 scopus 로고    scopus 로고
    • Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins
    • Tsukamoto T and Nigam SK. Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. Am J Physiol Renal Physiol 276: F737-F750, 1999.
    • (1999) Am J Physiol Renal Physiol , vol.276
    • Tsukamoto, T.1    Nigam, S.K.2
  • 143
  • 144
    • 0036336486 scopus 로고    scopus 로고
    • Permeability barrier dysfunction in transgenic mice overexpressing claudin 6
    • Turksen K and Troy TC. Permeability barrier dysfunction in transgenic mice overexpressing claudin 6. Development 129: 1775-1784, 2002.
    • (2002) Development , vol.129 , pp. 1775-1784
    • Turksen, K.1    Troy, T.C.2
  • 145
    • 0030983484 scopus 로고    scopus 로고
    • Occludin confers adhesiveness when expressed in fibroblasts
    • Van Itallie CM and Anderson JM. Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci 110: 1113-1121, 1997.
    • (1997) J Cell Sci , vol.110 , pp. 1113-1121
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 146
    • 0035013499 scopus 로고    scopus 로고
    • Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability
    • Van Itallie C, Rahner C, and Anderson JM. Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability. J Clin Invest 107: 1319-1327, 2001.
    • (2001) J Clin Invest , vol.107 , pp. 1319-1327
    • Van Itallie, C.1    Rahner, C.2    Anderson, J.M.3
  • 147
    • 0037145045 scopus 로고    scopus 로고
    • Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape
    • Walters RW, Freimuth P, Zabner J, and Welsh MJ. Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape. Cell 110: 789-799, 2002.
    • (2002) Cell , vol.110 , pp. 789-799
    • Walters, R.W.1    Freimuth, P.2    Zabner, J.3    Welsh, M.J.4
  • 148
    • 0034112105 scopus 로고    scopus 로고
    • Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1
    • Wan H, Winton HL, Soeller C, Gruenert DC, Thompson PJ, Cannell MB, Stewart GA, Garrod DR, and Robinson C. Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1. Clin Exp Allergy 30: 685-698, 2000.
    • (2000) Clin Exp Allergy , vol.30 , pp. 685-698
    • Wan, H.1    Winton, H.L.2    Soeller, C.3    Gruenert, D.C.4    Thompson, P.J.5    Cannell, M.B.6    Stewart, G.A.7    Garrod, D.R.8    Robinson, C.9
  • 151
    • 0034891627 scopus 로고    scopus 로고
    • Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers
    • Watson CJ, Rowland M, and Warhurst G, Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers. Am J Physiol Cell Physiol 281: C388-C397, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Watson, C.J.1    Rowland, M.2    Warhurst, G.3
  • 154
    • 0027240084 scopus 로고
    • The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions
    • Willott E, Balda MS, Fanning AS, Jameson B, Van Itallie C, and Anderson JM. The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc Natl Acad Sci USA 90: 7834-7838, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7834-7838
    • Willott, E.1    Balda, M.S.2    Fanning, A.S.3    Jameson, B.4    Van Itallie, C.5    Anderson, J.M.6
  • 156
    • 0034645048 scopus 로고    scopus 로고
    • Exogenous expression of the amino-terminal half of the tight junction protein ZO-3 perturbs junctional complex assembly
    • Wittchen ES, Haskins J, and Stevenson BR. Exogenous expression of the amino-terminal half of the tight junction protein ZO-3 perturbs junctional complex assembly. J Cell Biol 151: 825-836, 2000.
    • (2000) J Cell Biol , vol.151 , pp. 825-836
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 157
    • 0038586530 scopus 로고    scopus 로고
    • NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: Linking a tight junction protein to Rho GTPases
    • Wittchen ES, Haskins J, and Stevenson BR. NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: linking a tight junction protein to Rho GTPases. Mol Biol Cell 14: 1757-1768, 2003.
    • (2003) Mol Biol Cell , vol.14 , pp. 1757-1768
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 158
    • 0033521140 scopus 로고    scopus 로고
    • Protein interactions at the tight junction. Actin has multiple binding partners and ZO-I forms independent complexes with ZO-2 and ZO-3
    • Wittchen ES, Haskins J, and Stevenson BR. Protein interactions at the tight junction. Actin has multiple binding partners and ZO-I forms independent complexes with ZO-2 and ZO-3. J Biol Chem 274: 35179-35185, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 35179-35185
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 159
    • 0031047483 scopus 로고    scopus 로고
    • A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier
    • Wong V and Gumbiner BM. A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J Cell Biol 136: 399-409, 1997.
    • (1997) J Cell Biol , vol.136 , pp. 399-409
    • Wong, V.1    Gumbiner, B.M.2
  • 161
    • 0034647496 scopus 로고    scopus 로고
    • Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI-3, a novel membrane-associated guanylate kinase
    • Wu Y, Dowbenko D, Spencer S, Laura R, Lee J, Gu Q, and Lasky LA. Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI-3, a novel membrane-associated guanylate kinase. J Biol Chem 275: 21477-21485, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 21477-21485
    • Wu, Y.1    Dowbenko, D.2    Spencer, S.3    Laura, R.4    Lee, J.5    Gu, Q.6    Lasky, L.A.7
  • 162
    • 0030724368 scopus 로고    scopus 로고
    • The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells
    • Yamamoto T, Harada N, Kano K, Taya S, Canaani E, Matsuura Y, Mizoguchi A, CI, and Kaibuchi K. The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cells. J Cell Biol 139: 785-795, 1997.
    • (1997) J Cell Biol , vol.139 , pp. 785-795
    • Yamamoto, T.1    Harada, N.2    Kano, K.3    Taya, S.4    Canaani, E.5    Matsuura, Y.6    Mizoguchi, A.7    Kaibuchi, K.8
  • 165
    • 0037930880 scopus 로고    scopus 로고
    • Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation
    • Yu AS, Enck AH, Lencer WI, and Schneeberger EE. Claudin-8 expression in Madin-Darby canine kidney cells augments the paracellular barrier to cation permeation. J Biol Chem 278: 17350-17359, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 17350-17359
    • Yu, A.S.1    Enck, A.H.2    Lencer, W.I.3    Schneeberger, E.E.4
  • 166
    • 0028008838 scopus 로고
    • A small rab GTPase is distributed in cytoplasmic vesicles in nonpolarized cells but colocalizes with the TJ marker ZO-1 in polarized epithelial cells
    • Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, and Louvard D. A small rab GTPase is distributed in cytoplasmic vesicles in nonpolarized cells but colocalizes with the TJ marker ZO-1 in polarized epithelial cells. J Cell Biol 124: 101-115, 1994.
    • (1994) J Cell Biol , vol.124 , pp. 101-115
    • Zahraoui, A.1    Joberty, G.2    Arpin, M.3    Fontaine, J.J.4    Hellio, R.5    Tavitian, A.6    Louvard, D.7
  • 167
    • 0027393734 scopus 로고
    • Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2
    • Zhong Y, Saitoh T, Minase T, Sawada N, Enomoto K, and Mori M. Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J Cell Biol 120: 477-483, 1993.
    • (1993) J Cell Biol , vol.120 , pp. 477-483
    • Zhong, Y.1    Saitoh, T.2    Minase, T.3    Sawada, N.4    Enomoto, K.5    Mori, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.