Histone deacetylase inhibitor trichostatin a induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells

International Journal of Cancer

Volumn 103, Issue 5, 2003, Pages 572-576

  Yamashita, Yo ichi ^a   Shimada, Mitsuo ^a   Harimoto, Norifumi ^a   Rikimaru, Tatsuya ^a   Shirabe, Ken ^a   Tanaka, Shinj ^a   Sugimachi, Keizo ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

HepG2; Hepotocyte differentiation; Histone deacetylase inhibitor; Huh 7; Trichostatin A

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HISTONE H4; TRICHOSTATIN A;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL GROWTH; CELL STRAIN HEPG2; CHROMATIN; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME INHIBITION; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER FUNCTION; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ALBUMINS; AMMONIA; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTES; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; LIVER NEOPLASMS; NEOPLASM PROTEINS; TUMOR CELLS, CULTURED;

EID: 0037455825     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10699     Document Type: Article

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