-
1
-
-
4644259153
-
Cellular oxygen sensing need in CNS function: Physiological and pathological implications
-
Acker T and Acker H. Cellular oxygen sensing need in CNS function: physiological and pathological implications. J Exp Biol 207: 3171-3188, 2004.
-
(2004)
J Exp Biol
, vol.207
, pp. 3171-3188
-
-
Acker, T.1
Acker, H.2
-
2
-
-
0036132872
-
c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription
-
Alfranca A, Gutierrez MD, Vara A, Aragones J, Vidal F, and Landazuri MO. c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. Mol Cell Biol 22: 12-22, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 12-22
-
-
Alfranca, A.1
Gutierrez, M.D.2
Vara, A.3
Aragones, J.4
Vidal, F.5
Landazuri, M.O.6
-
3
-
-
4344693268
-
Glial modulation of synaptic transmission in culture
-
Araque A and Perea G. Glial modulation of synaptic transmission in culture. Glia 47: 241-248, 2004.
-
(2004)
Glia
, vol.47
, pp. 241-248
-
-
Araque, A.1
Perea, G.2
-
4
-
-
0141884303
-
Glial cells and neurotransmission: An inclusive view of synaptic function
-
Auld DS and Robitaille R. Glial cells and neurotransmission: an inclusive view of synaptic function. Neuron 40: 389-400, 2003.
-
(2003)
Neuron
, vol.40
, pp. 389-400
-
-
Auld, D.S.1
Robitaille, R.2
-
5
-
-
0034937247
-
Hypoxia induces an excitotoxic-type of dark cell degeneration in cerebellar Purkinje neurons
-
Barenberg P, Strahlendorf H, and Strahlendorf J. Hypoxia induces an excitotoxic-type of dark cell degeneration in cerebellar Purkinje neurons. Neurosci Res 40: 245-254, 2001.
-
(2001)
Neurosci Res
, vol.40
, pp. 245-254
-
-
Barenberg, P.1
Strahlendorf, H.2
Strahlendorf, J.3
-
6
-
-
1842632327
-
Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5
-
Bemis L, Chan DA, Finkielstein CV, Qi L, Sutphin PD, Chen X, Stenmark K, Giaccia AJ, and Zundel W. Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5. Genes Dev 18: 739-744, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 739-744
-
-
Bemis, L.1
Chan, D.A.2
Finkielstein, C.V.3
Qi, L.4
Sutphin, P.D.5
Chen, X.6
Stenmark, K.7
Giaccia, A.J.8
Zundel, W.9
-
7
-
-
0037337061
-
The subtle side to hypoxia inducible factor (HIFalpha) regulation
-
Bilton RL and Booker GW. The subtle side to hypoxia inducible factor (HIFalpha) regulation. Eur J Biochem 270: 791-798, 2003.
-
(2003)
Eur J Biochem
, vol.270
, pp. 791-798
-
-
Bilton, R.L.1
Booker, G.W.2
-
8
-
-
0026494916
-
Hypoxic induction of the human erythropoietin gene: Cooperation between the promoter and enhancer, each of which contains steroid receptor response elements
-
Blanchard KL, Acquaviva AM, Galson DL, and Bunn HF. Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements. Mol Cell Biol 12: 5373-5385, 1992.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5373-5385
-
-
Blanchard, K.L.1
Acquaviva, A.M.2
Galson, D.L.3
Bunn, H.F.4
-
9
-
-
3042798646
-
Dual-gene, dual-cell type therapy against an excitotoxic insult by bolstering neuroenergetics
-
Bliss TM, Ip M, Cheng E, Minami M, Pellerin L, Magistretti P, and Sapolsky RM. Dual-gene, dual-cell type therapy against an excitotoxic insult by bolstering neuroenergetics. J Neurosci 24: 6202-6208, 2004.
-
(2004)
J Neurosci
, vol.24
, pp. 6202-6208
-
-
Bliss, T.M.1
Ip, M.2
Cheng, E.3
Minami, M.4
Pellerin, L.5
Magistretti, P.6
Sapolsky, R.M.7
-
10
-
-
11144298043
-
+ exchange in hypoxia-related acute astrocyte death
-
+ exchange in hypoxia-related acute astrocyte death. Glia 49: 143-152, 2005.
-
(2005)
Glia
, vol.49
, pp. 143-152
-
-
Bondarenko, A.1
Svichar, N.2
Chesler, M.3
-
11
-
-
0035124927
-
Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim
-
Bouillet P, Zhang LC, Huang DC, Webb GC, Bottema CD, Shore P, Eyre HJ, Sutherland GR, and Adams JM. Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim. Mamm Genome 12: 163-168, 2001.
-
(2001)
Mamm Genome
, vol.12
, pp. 163-168
-
-
Bouillet, P.1
Zhang, L.C.2
Huang, D.C.3
Webb, G.C.4
Bottema, C.D.5
Shore, P.6
Eyre, H.J.7
Sutherland, G.R.8
Adams, J.M.9
-
12
-
-
0042368882
-
The hypoxia-inducible factors: Key transcriptional regulators of hypoxic responses
-
Bracken CP, Whitelaw ML, and Peet DJ. The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses. Cell Mol Life Sci 60: 1376-1393, 2003.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1376-1393
-
-
Bracken, C.P.1
Whitelaw, M.L.2
Peet, D.J.3
-
13
-
-
4744339911
-
Role of cytokines and chemokines in prion infections of the central nervous system
-
Burwinkel M, Riemer C, Schwarz A, Schultz J, Neidhold S, Bamme T, and Baier M. Role of cytokines and chemokines in prion infections of the central nervous system. Int J Dev Neurosci 22: 497-505, 2004.
-
(2004)
Int J Dev Neurosci
, vol.22
, pp. 497-505
-
-
Burwinkel, M.1
Riemer, C.2
Schwarz, A.3
Schultz, J.4
Neidhold, S.5
Bamme, T.6
Baier, M.7
-
14
-
-
0036668567
-
Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): Trends and problems
-
Bustin SA. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J Mol Endocrinol 29: 23-39, 2002.
-
(2002)
J Mol Endocrinol
, vol.29
, pp. 23-39
-
-
Bustin, S.A.1
-
15
-
-
0034875864
-
Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes
-
Canki M, Thai JN, Chao W, Ghorpade A, Potash MJ, and Volsky DJ. Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes. J Virol 75: 7925-7933, 2001.
-
(2001)
J Virol
, vol.75
, pp. 7925-7933
-
-
Canki, M.1
Thai, J.N.2
Chao, W.3
Ghorpade, A.4
Potash, M.J.5
Volsky, D.J.6
-
16
-
-
0037806885
-
Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway
-
Chang F, Steelman LS, Shelton JG, Lee JT, Navolanic PM, Blalock WL, Franklin R, and McCubrey JA. Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway. Int J Oncol 22: 469-480, 2003.
-
(2003)
Int J Oncol
, vol.22
, pp. 469-480
-
-
Chang, F.1
Steelman, L.S.2
Shelton, J.G.3
Lee, J.T.4
Navolanic, P.M.5
Blalock, W.L.6
Franklin, R.7
McCubrey, J.A.8
-
18
-
-
0347993706
-
Oxygen sensing: Applications in humans
-
Cherniack NS. Oxygen sensing: applications in humans. J Appl Physiol 96: 352-358, 2004.
-
(2004)
J Appl Physiol
, vol.96
, pp. 352-358
-
-
Cherniack, N.S.1
-
19
-
-
20344380470
-
Failure and function of intracellular pH regulation in acute hypoxic-ischemic injury of astrocytes
-
Chesler M. Failure and function of intracellular pH regulation in acute hypoxic-ischemic injury of astrocytes. Glia 50: 398-406, 2005.
-
(2005)
Glia
, vol.50
, pp. 398-406
-
-
Chesler, M.1
-
20
-
-
13844255713
-
Anti-inflammatory roles of retinoic acid in rat brain astrocytes: Suppression of interferon-gamma-induced JAK/STAT phosphorylation
-
Choi WH, Ji KA, Jeon SB, Yang MS, Kim H, Min KJ, Shong M, Jou I, and Joe EH. Anti-inflammatory roles of retinoic acid in rat brain astrocytes: suppression of interferon-gamma-induced JAK/STAT phosphorylation. Biochem Biophys Res Commun 329: 125-131, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 125-131
-
-
Choi, W.H.1
Ji, K.A.2
Jeon, S.B.3
Yang, M.S.4
Kim, H.5
Min, K.J.6
Shong, M.7
Jou, I.8
Joe, E.H.9
-
21
-
-
4344685239
-
Glial modulation of synaptic transmission at the neuromuscular junction
-
Colomar A and Robitaille R. Glial modulation of synaptic transmission at the neuromuscular junction. Glia 47: 284-289, 2004.
-
(2004)
Glia
, vol.47
, pp. 284-289
-
-
Colomar, A.1
Robitaille, R.2
-
22
-
-
10844278331
-
2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia
-
2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res 64: 9057-9061, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 9057-9061
-
-
Comerford, K.M.1
Cummins, E.P.2
Taylor, C.T.3
-
23
-
-
0032965705
-
Regulation of gene expression and secretory functions in oxygen-sensing pheochromocytoma cells
-
Conforti L, Kobayashi S, Beitner-Johnson D, Conrad PW, Freeman T, and Millhorn DE. Regulation of gene expression and secretory functions in oxygen-sensing pheochromocytoma cells. Respir Physiol 115: 249-260, 1999.
-
(1999)
Respir Physiol
, vol.115
, pp. 249-260
-
-
Conforti, L.1
Kobayashi, S.2
Beitner-Johnson, D.3
Conrad, P.W.4
Freeman, T.5
Millhorn, D.E.6
-
24
-
-
0034746307
-
2-sensing and hypoxia tolerance in pheochromocytoma cells
-
2-sensing and hypoxia tolerance in pheochromocytoma cells. Comp Biochem Physiol B Biochem Mol Biol 128: 187-204, 2001.
-
(2001)
Comp Biochem Physiol B Biochem Mol Biol
, vol.128
, pp. 187-204
-
-
Conrad, P.W.1
Conforti, L.2
Kobayashi, S.3
Beitner-Johnson, D.4
Rust, R.T.5
Yuan, Y.6
Kim, H.W.7
Kim, R.H.8
Seta, K.9
Millhorn, D.E.10
-
25
-
-
16644389516
-
HIFs, hypoxia, and vascular development
-
Covello KL and Simon MC. HIFs, hypoxia, and vascular development. Curr Top Dev Biol 62: 37-54, 2004.
-
(2004)
Curr Top Dev Biol
, vol.62
, pp. 37-54
-
-
Covello, K.L.1
Simon, M.C.2
-
26
-
-
0032982678
-
Erythropoietin production: Evidence for multiple oxygen sensing pathways
-
Daghman NA, Elder GE, Savage GA, Winter PC, Maxwell AP, and Lappin TR. Erythropoietin production: evidence for multiple oxygen sensing pathways. Ann Hematol 78: 275-278, 1999.
-
(1999)
Ann Hematol
, vol.78
, pp. 275-278
-
-
Daghman, N.A.1
Elder, G.E.2
Savage, G.A.3
Winter, P.C.4
Maxwell, A.P.5
Lappin, T.R.6
-
27
-
-
0034632052
-
p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia
-
Denko NC, Green SL, Edwards D, and Giaccia AJ. p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia. Exp Cell Res 258: 82-91, 2000.
-
(2000)
Exp Cell Res
, vol.258
, pp. 82-91
-
-
Denko, N.C.1
Green, S.L.2
Edwards, D.3
Giaccia, A.J.4
-
28
-
-
20344364186
-
Astrocytic contributions to bioenergetics of cerebral ischemia
-
Dienel GA and Hertz L. Astrocytic contributions to bioenergetics of cerebral ischemia. Glia 50: 362-388, 2005.
-
(2005)
Glia
, vol.50
, pp. 362-388
-
-
Dienel, G.A.1
Hertz, L.2
-
29
-
-
33646370776
-
Cell type-dependent regulation of the hypoxia-responsive plasminogen activator inhibitor-1 gene by upstream stimulatory factor-2
-
Dimova EY and Kietzmann T. Cell type-dependent regulation of the hypoxia-responsive plasminogen activator inhibitor-1 gene by upstream stimulatory factor-2. J Biol Chem 281: 2999-3005, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 2999-3005
-
-
Dimova, E.Y.1
Kietzmann, T.2
-
30
-
-
1342321750
-
PI 3-kinase, Akt and cell survival
-
Downward J. PI 3-kinase, Akt and cell survival. Semin Cell Dev Biol 15: 177-182, 2004.
-
(2004)
Semin Cell Dev Biol
, vol.15
, pp. 177-182
-
-
Downward, J.1
-
31
-
-
0033566693
-
Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2
-
Feldser D, Agani F, Iyer NV, Pak B, Ferreira G, and Semenza GL. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Res 59: 3915-398, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 3915-4398
-
-
Feldser, D.1
Agani, F.2
Iyer, N.V.3
Pak, B.4
Ferreira, G.5
Semenza, G.L.6
-
32
-
-
0037131025
-
New insights into neuron-glia communication
-
Fields RD and Stevens-Graham B. New insights into neuron-glia communication. Science 298: 556-562, 2002.
-
(2002)
Science
, vol.298
, pp. 556-562
-
-
Fields, R.D.1
Stevens-Graham, B.2
-
33
-
-
0028967752
-
The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1
-
Galson DL, Tsuchiya T, Tendler DS, Huang LE, Ren Y, Ogura T, and Bunn HF. The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1. Mol Cell Biol 15: 2135-2144, 1995.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2135-2144
-
-
Galson, D.L.1
Tsuchiya, T.2
Tendler, D.S.3
Huang, L.E.4
Ren, Y.5
Ogura, T.6
Bunn, H.F.7
-
34
-
-
0033529243
-
DIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development
-
Garcia-Domingo D, Leonardo E, Grandien A, Martinez P, Albar JP, Izpisua-Belmonte JC, and Martinez AC. DIO-1 is a gene involved in onset of apoptosis in vitro, whose misexpression disrupts limb development. Proc Natl Acad Sci USA 96: 7992-7997, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7992-7997
-
-
Garcia-Domingo, D.1
Leonardo, E.2
Grandien, A.3
Martinez, P.4
Albar, J.P.5
Izpisua-Belmonte, J.C.6
Martinez, A.C.7
-
35
-
-
0035399785
-
Microglia in neurodegeneration: Molecular aspects
-
Gebicke-Haerter PJ. Microglia in neurodegeneration: molecular aspects. Microsc Res Tech 54: 47-58, 2001.
-
(2001)
Microsc Res Tech
, vol.54
, pp. 47-58
-
-
Gebicke-Haerter, P.J.1
-
36
-
-
0035710229
-
An overview of real-time quantitative PCR: Applications to quantify cytokine gene expression
-
Giulietti A, Overbergh L, Valckx D, Decallonne B, Bouillon R, and Mathieu C. An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25: 386-401, 2001.
-
(2001)
Methods
, vol.25
, pp. 386-401
-
-
Giulietti, A.1
Overbergh, L.2
Valckx, D.3
Decallonne, B.4
Bouillon, R.5
Mathieu, C.6
-
37
-
-
4043110513
-
Lactate metabolism: A new paradigm for the third millennium
-
Gladden LB. Lactate metabolism: a new paradigm for the third millennium. J Physiol 558: 5-30, 2004.
-
(2004)
J Physiol
, vol.558
, pp. 5-30
-
-
Gladden, L.B.1
-
39
-
-
0036556492
-
Role of glia-derived cholesterol in synaptogenesis: New revelations in the synapseglia affair
-
Goritz C, Mauch DH, Nagler K, and Pfrieger FW. Role of glia-derived cholesterol in synaptogenesis: new revelations in the synapseglia affair. J Physiol 96: 257-263, 2002.
-
(2002)
J Physiol
, vol.96
, pp. 257-263
-
-
Goritz, C.1
Mauch, D.H.2
Nagler, K.3
Pfrieger, F.W.4
-
40
-
-
0034116376
-
The PAS superfamily: Sensors of environmental and developmental signals
-
Gu YZ, Hogenesch JB, and Bradfield CA. The PAS superfamily: sensors of environmental and developmental signals. Annu Rev Pharmacol Toxicol 40: 519-561, 2000.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 519-561
-
-
Gu, Y.Z.1
Hogenesch, J.B.2
Bradfield, C.A.3
-
41
-
-
1242296872
-
Inducible, reversible, and stable RNA interference in mammalian cells
-
Gupta S, Schoer RA, Egan JE, Hannon GJ, and Mittal V. Inducible, reversible, and stable RNA interference in mammalian cells. Proc Natl Acad Sci USA 101: 1927-1932, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 1927-1932
-
-
Gupta, S.1
Schoer, R.A.2
Egan, J.E.3
Hannon, G.J.4
Mittal, V.5
-
43
-
-
1542348215
-
Neurodegeneration or neuroprotection: The pivotal role of astrocytes
-
Heales SJ, Lam AA, Duncan AJ, and Land JM. Neurodegeneration or neuroprotection: the pivotal role of astrocytes. Neurochem Res 29: 513-519, 2004.
-
(2004)
Neurochem Res
, vol.29
, pp. 513-519
-
-
Heales, S.J.1
Lam, A.A.2
Duncan, A.J.3
Land, J.M.4
-
44
-
-
2442546861
-
Intercellular metabolic compartmentation in the brain: Past, present and future
-
Hertz L. Intercellular metabolic compartmentation in the brain: past, present and future. Neurochem Int 45: 285-296, 2004.
-
(2004)
Neurochem Int
, vol.45
, pp. 285-296
-
-
Hertz, L.1
-
45
-
-
13244300647
-
Exposure of astrocytes to hypoxia/reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6
-
Hori O, Matsumoto M, Kuwabara K, Maeda Y, Ueda H, Ohtsuki T, Kinoshita T, Ogawa S, Stern DM, and Kamada T. Exposure of astrocytes to hypoxia/ reoxygenation enhances expression of glucose-regulated protein 78 facilitating astrocyte release of the neuroprotective cytokine interleukin 6. J Neurochem 66: 973-979, 1996.
-
(1996)
J Neurochem
, vol.66
, pp. 973-979
-
-
Hori, O.1
Matsumoto, M.2
Kuwabara, K.3
Maeda, Y.4
Ueda, H.5
Ohtsuki, T.6
Kinoshita, T.7
Ogawa, S.8
Stern, D.M.9
Kamada, T.10
-
46
-
-
0031045834
-
In vivo analysis of DNA-protein interactions on the human erythropoietin enhancer
-
Hu B, Wright E, Campbell L, and Blanchard KL. In vivo analysis of DNA-protein interactions on the human erythropoietin enhancer. Mol Cell Biol 17: 851-856, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 851-856
-
-
Hu, B.1
Wright, E.2
Campbell, L.3
Blanchard, K.L.4
-
47
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
-
Huang LE, Arany Z, Livingston DM, and Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem 271: 32253-32259, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
48
-
-
0038434290
-
Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells
-
Jeong HJ, Chung HS, Lee BR, Kim SJ, Yoo SJ, Hong SH, and Kim HM. Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells. Biochem Biophys Res Commun 306: 805-811, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.306
, pp. 805-811
-
-
Jeong, H.J.1
Chung, H.S.2
Lee, B.R.3
Kim, S.J.4
Yoo, S.J.5
Hong, S.H.6
Kim, H.M.7
-
49
-
-
0034064581
-
Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: Role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection
-
Kacimi R, Chentoufi J, Honbo N, Long CS, and Karliner JS. Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection. Cardiovasc Res 46: 139-150, 2000.
-
(2000)
Cardiovasc Res
, vol.46
, pp. 139-150
-
-
Kacimi, R.1
Chentoufi, J.2
Honbo, N.3
Long, C.S.4
Karliner, J.S.5
-
50
-
-
22244440847
-
Proline hydroxylation and gene expression
-
Kaelin WG. Proline hydroxylation and gene expression. Annu Rev Biochem 74: 115-128, 2005.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 115-128
-
-
Kaelin, W.G.1
-
51
-
-
0035912198
-
Pathways to neuronal injury and apoptosis in HIV-associated dementia
-
Kaul M, Garden GA, and Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410: 988-994, 2001.
-
(2001)
Nature
, vol.410
, pp. 988-994
-
-
Kaul, M.1
Garden, G.A.2
Lipton, S.A.3
-
52
-
-
20344374445
-
Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy
-
Kimelberg HK. Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy. Glia 50: 389-397, 2005.
-
(2005)
Glia
, vol.50
, pp. 389-397
-
-
Kimelberg, H.K.1
-
53
-
-
0038526243
-
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells
-
Kitamuro T, Takahashi K, Ogawa K, Udono-Fujimori R, Takeda K, Furuyama K, Nakayama M, Sun J, Fujita H, Hida W, Hattori T, Shirato K, Igarashi K, and Shibahara S. Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells. J Biol Chem 278: 9125-9133, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 9125-9133
-
-
Kitamuro, T.1
Takahashi, K.2
Ogawa, K.3
Udono-Fujimori, R.4
Takeda, K.5
Furuyama, K.6
Nakayama, M.7
Sun, J.8
Fujita, H.9
Hida, W.10
Hattori, T.11
Shirato, K.12
Igarashi, K.13
Shibahara, S.14
-
54
-
-
13144275217
-
Dynamic balancing of the dual nature of HIF-1alpha for cell survival
-
Koshiji M and Huang LE. Dynamic balancing of the dual nature of HIF-1alpha for cell survival. Cell Cycle 3: 853-854, 2004.
-
(2004)
Cell Cycle
, vol.3
, pp. 853-854
-
-
Koshiji, M.1
Huang, L.E.2
-
55
-
-
3142631736
-
HIF-1alpha induces cell cycle arrest by functionally counteracting Myc
-
Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barrett JC, and Huang LE. HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. EMBO J 23: 1949-1956, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 1949-1956
-
-
Koshiji, M.1
Kageyama, Y.2
Pete, E.A.3
Horikawa, I.4
Barrett, J.C.5
Huang, L.E.6
-
56
-
-
0043091971
-
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
-
Kothari S, Cizeau J, McMillan-Ward E, Israels SJ, Bailes M, Ens K, Kirshenbaum LA, and Gibson SB. BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22: 4734-4744, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 4734-4744
-
-
Kothari, S.1
Cizeau, J.2
McMillan-Ward, E.3
Israels, S.J.4
Bailes, M.5
Ens, K.6
Kirshenbaum, L.A.7
Gibson, S.B.8
-
57
-
-
0035140981
-
Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation
-
Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M, Derr J, Taya Y, Lowe SW, Kastan M, and Giaccia A. Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Mol Cell Biol 21: 1297-1310, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1297-1310
-
-
Koumenis, C.1
Alarcon, R.2
Hammond, E.3
Sutphin, P.4
Hoffman, W.5
Murphy, M.6
Derr, J.7
Taya, Y.8
Lowe, S.W.9
Kastan, M.10
Giaccia, A.11
-
58
-
-
0029915707
-
Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain
-
Kuwabara K, Matsumoto M, Ikeda J, Hori O, Ogawa S, Maeda Y, Kitagawa K, Imuta N, Kinoshita T, Stern DM, Yanagi H, and Kamada T. Purification and characterization of a novel stress protein, the 150-kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain. J Biol Chem 271: 5025-5032, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 5025-5032
-
-
Kuwabara, K.1
Matsumoto, M.2
Ikeda, J.3
Hori, O.4
Ogawa, S.5
Maeda, Y.6
Kitagawa, K.7
Imuta, N.8
Kinoshita, T.9
Stern, D.M.10
Yanagi, H.11
Kamada, T.12
-
59
-
-
0031035576
-
The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive
-
Kvietikova I, Wenger RH, Marti HH, and Gassmann M. The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive. Kidney Int 51: 564-566, 1997.
-
(1997)
Kidney Int
, vol.51
, pp. 564-566
-
-
Kvietikova, I.1
Wenger, R.H.2
Marti, H.H.3
Gassmann, M.4
-
60
-
-
0028891906
-
The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site
-
Kvietikova I, Wenger RH, Marti HH, and Gassmann M. The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. Nucleic Acids Res 23: 4542-45450, 1995.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4542-45450
-
-
Kvietikova, I.1
Wenger, R.H.2
Marti, H.H.3
Gassmann, M.4
-
61
-
-
0036210708
-
The response of c-jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1 alpha dependent
-
Laderoute KR, Calaoagan JM, Gustafson-Brown C, Knapp AM, Li GC, Mendonca HL, Ryan HE, Wang Z, and Johnson RS. The response of c-jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1 alpha dependent. Mol Cell Biol 22: 2515-2523, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2515-2523
-
-
Laderoute, K.R.1
Calaoagan, J.M.2
Gustafson-Brown, C.3
Knapp, A.M.4
Li, G.C.5
Mendonca, H.L.6
Ryan, H.E.7
Wang, Z.8
Johnson, R.S.9
-
62
-
-
2942568513
-
Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun
-
Laderoute KR, Calaoagan JM, Knapp M, and Johnson RS. Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun. Mol Cell Biol 24: 4128-4137, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4128-4137
-
-
Laderoute, K.R.1
Calaoagan, J.M.2
Knapp, M.3
Johnson, R.S.4
-
63
-
-
0035083678
-
Astrocytes produce and release interleukin-1, interleukin-6, tumor necrosis factor alpha and interferon-gamma following traumatic and metabolic injury
-
Lau LT and Yu AC. Astrocytes produce and release interleukin-1, interleukin-6, tumor necrosis factor alpha and interferon-gamma following traumatic and metabolic injury. J Neurotrauma 18: 351-359, 2001.
-
(2001)
J Neurotrauma
, vol.18
, pp. 351-359
-
-
Lau, L.T.1
Yu, A.C.2
-
64
-
-
0031041377
-
Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
-
Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, and Choi AM. Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 5375-5381
-
-
Lee, P.J.1
Jiang, B.H.2
Chin, B.Y.3
Iyer, N.V.4
Alam, J.5
Semenza, G.L.6
Choi, A.M.7
-
65
-
-
0038449116
-
EGF receptor as a therapeutic target
-
Levitzki A. EGF receptor as a therapeutic target. Lung Cancer 41, Suppl 1: S9-S14, 2003.
-
(2003)
Lung Cancer
, vol.41
, Issue.1 SUPPL.
-
-
Levitzki, A.1
-
66
-
-
2342618936
-
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
-
Liang J and Slingerland JM. Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2: 339-345, 2003.
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
67
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ and Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
69
-
-
11244315697
-
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
-
Manalo DJ, Rowan A, Lavoie T, Natarajan L, Kelly BD, Ye SQ, Garcia JG, and Semenza GL. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 105: 659-669, 2005.
-
(2005)
Blood
, vol.105
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.7
Semenza, G.L.8
-
70
-
-
8444250215
-
A neural signaling triumvirate that influences ageing and age-related disease: Insulin/IGF-1, BDNF and serotonin
-
Mattson MP, Maudsley S, and Martin B. A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin. Ageing Res Rev 3: 445-464, 2004.
-
(2004)
Ageing Res Rev
, vol.3
, pp. 445-464
-
-
Mattson, M.P.1
Maudsley, S.2
Martin, B.3
-
71
-
-
4143110440
-
HIF-1: Master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs
-
Mazure NM, Brahimi-Horn MC, Berta MA, Benizri E, Bilton RL, Dayan F, Ginouves A, Berra E, and Pouyssegur J. HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs. Biochem Pharmacol 68: 971-980, 2004.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 971-980
-
-
Mazure, N.M.1
Brahimi-Horn, M.C.2
Berta, M.A.3
Benizri, E.4
Bilton, R.L.5
Dayan, F.6
Ginouves, A.7
Berra, E.8
Pouyssegur, J.9
-
72
-
-
20344383233
-
Auditory processing deficits in rats with neonatal hypoxic-ischemic injury
-
McClure MM, Peiffer AM, Rosen GD, and Fitch RH. Auditory processing deficits in rats with neonatal hypoxic-ischemic injury. Int J Dev Neurosci 23: 351-362, 2005.
-
(2005)
Int J Dev Neurosci
, vol.23
, pp. 351-362
-
-
McClure, M.M.1
Peiffer, A.M.2
Rosen, G.D.3
Fitch, R.H.4
-
73
-
-
0035690720
-
Glial activation in Alzheimer's disease: The role of Abeta and its associated proteins
-
Meda L, Baron P, and Scarlato G. Glial activation in Alzheimer's disease: the role of Abeta and its associated proteins. Neurobiol Aging 22: 885-893, 2001.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 885-893
-
-
Meda, L.1
Baron, P.2
Scarlato, G.3
-
74
-
-
17344395628
-
Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter
-
Meissner U, Ostreicher I, Allabauer I, Rascher W, and Dotsch J. Synergistic effects of hypoxia and insulin are regulated by different transcriptional elements of the human leptin promoter. Biochem Biophys Res Commun 303: 707-712, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 707-712
-
-
Meissner, U.1
Ostreicher, I.2
Allabauer, I.3
Rascher, W.4
Dotsch, J.5
-
75
-
-
2542450917
-
HIF hydroxylation and cellular oxygen sensing
-
Metzen E and Ratcliffe PJ. HIF hydroxylation and cellular oxygen sensing. Biol Chem 385: 223-230, 2004.
-
(2004)
Biol Chem
, vol.385
, pp. 223-230
-
-
Metzen, E.1
Ratcliffe, P.J.2
-
76
-
-
0034607632
-
Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols
-
Motterlini R, Foresti R, Bassi R, Calabrese V, Clark JE, and Green CJ. Endothelial heme oxygenase-1 induction by hypoxia. Modulation by inducible nitric-oxide synthase and S-nitrosothiols. J Biol Chem 275: 13613-13620, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 13613-13620
-
-
Motterlini, R.1
Foresti, R.2
Bassi, R.3
Calabrese, V.4
Clark, J.E.5
Green, C.J.6
-
77
-
-
20344394153
-
Role of glial cells in cerebral ischemia
-
Nedergaard M and Dirnagl U. Role of glial cells in cerebral ischemia. Glia 50: 281-286, 2005.
-
(2005)
Glia
, vol.50
, pp. 281-286
-
-
Nedergaard, M.1
Dirnagl, U.2
-
78
-
-
0141533205
-
New roles for astrocytes: Redefining the functional architecture of the brain
-
Nedergaard M, Ransom B, and Goldman SA. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 26: 523-530, 2003.
-
(2003)
Trends Neurosci
, vol.26
, pp. 523-530
-
-
Nedergaard, M.1
Ransom, B.2
Goldman, S.A.3
-
79
-
-
0347993707
-
Oxygen-sensing neurons in the central nervous system
-
Neubauer JA and Sunderram J. Oxygen-sensing neurons in the central nervous system. J Appl Physiol 96: 367-374, 2004.
-
(2004)
J Appl Physiol
, vol.96
, pp. 367-374
-
-
Neubauer, J.A.1
Sunderram, J.2
-
80
-
-
0141867841
-
New roles for astrocytes: Regulation of synaptic transmission
-
Newman EA. New roles for astrocytes: regulation of synaptic transmission. Trends Neurosci 26: 536-542, 2003.
-
(2003)
Trends Neurosci
, vol.26
, pp. 536-542
-
-
Newman, E.A.1
-
81
-
-
20344366326
-
Astrocytes in cerebral ischemic injury: Morphological and general considerations
-
Panickar KS and Norenberg MD. Astrocytes in cerebral ischemic injury: morphological and general considerations. Glia 50: 287-298, 2005.
-
(2005)
Glia
, vol.50
, pp. 287-298
-
-
Panickar, K.S.1
Norenberg, M.D.2
-
82
-
-
0036909402
-
Regulation of protein kinases in insulin, growth factor and Wnt signalling
-
Pearl LH and Barford D. Regulation of protein kinases in insulin, growth factor and Wnt signalling. Curr Opin Struct Biol 12: 761-767, 2002.
-
(2002)
Curr Opin Struct Biol
, vol.12
, pp. 761-767
-
-
Pearl, L.H.1
Barford, D.2
-
83
-
-
20344398223
-
Astrocyte activation and reactive gliosis
-
Pekny M and Nilsson M. Astrocyte activation and reactive gliosis. Glia 50: 427-434, 2005.
-
(2005)
Glia
, vol.50
, pp. 427-434
-
-
Pekny, M.1
Nilsson, M.2
-
84
-
-
7944223409
-
Astrocyte intermediate filaments in CNS pathologies and regeneration
-
Pekny M and Pekna M. Astrocyte intermediate filaments in CNS pathologies and regeneration. J Pathol 204: 428-437, 2004.
-
(2004)
J Pathol
, vol.204
, pp. 428-437
-
-
Pekny, M.1
Pekna, M.2
-
85
-
-
1642457265
-
Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons
-
Pellerin L and Magistretti PJ. Neuroenergetics: calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10: 53-62, 2004.
-
(2004)
Neuroscientist
, vol.10
, pp. 53-62
-
-
Pellerin, L.1
Magistretti, P.J.2
-
86
-
-
2942624259
-
A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation
-
Percy MJ, Mooney SM, McMullin MF, Flores A, Lappin TR, and Lee FS. A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation. Mol Cancer 2: 31, 2003.
-
(2003)
Mol Cancer
, vol.2
, pp. 31
-
-
Percy, M.J.1
Mooney, S.M.2
McMullin, M.F.3
Flores, A.4
Lappin, T.R.5
Lee, F.S.6
-
87
-
-
12144282625
-
Synaptic regulation of the astrocyte calcium signal
-
Perea G and Araque A. Synaptic regulation of the astrocyte calcium signal. J Neural Transm 112: 127-135, 2005.
-
(2005)
J Neural Transm
, vol.112
, pp. 127-135
-
-
Perea, G.1
Araque, A.2
-
88
-
-
20444445920
-
Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha
-
Phillips RJ, Mestas J, Gharaee-Kermani M, Burdick MD, Sica A, Belperio JA, Keane MP, and Strieter RM. Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. J Biol Chem 280: 22473-22481, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 22473-22481
-
-
Phillips, R.J.1
Mestas, J.2
Gharaee-Kermani, M.3
Burdick, M.D.4
Sica, A.5
Belperio, J.A.6
Keane, M.P.7
Strieter, R.M.8
-
89
-
-
0034793529
-
Transient oxygen-glucose deprivation induces rapid morphological changes in rat hippocampal dendrites
-
Piccini A and Malinow R. Transient oxygen-glucose deprivation induces rapid morphological changes in rat hippocampal dendrites. Neuropharmacology 41: 724-729, 2001.
-
(2001)
Neuropharmacology
, vol.41
, pp. 724-729
-
-
Piccini, A.1
Malinow, R.2
-
92
-
-
24344443670
-
Hypoxia-dependent activation of HIF into a transcriptional regulator
-
Ruas JL and Poellinger L. Hypoxia-dependent activation of HIF into a transcriptional regulator. Semin Cell Dev Biol 16: 514-522, 2005.
-
(2005)
Semin Cell Dev Biol
, vol.16
, pp. 514-522
-
-
Ruas, J.L.1
Poellinger, L.2
-
93
-
-
0036183640
-
The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia
-
Salnikow K, Kluz T, Costa M, Piquemal D, Demidenko ZN, Xie K, and Blagosklonny MV. The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia. Mol Cell Biol 22: 1734-1741, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1734-1741
-
-
Salnikow, K.1
Kluz, T.2
Costa, M.3
Piquemal, D.4
Demidenko, Z.N.5
Xie, K.6
Blagosklonny, M.V.7
-
94
-
-
0036470213
-
Insulin signaling pathways in time and space
-
Saltiel AR and Pessin JE. Insulin signaling pathways in time and space. Trends Cell Biol 12: 65-71, 2002.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 65-71
-
-
Saltiel, A.R.1
Pessin, J.E.2
-
95
-
-
0036333737
-
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
-
Scheid MP, Marignani PA, and Woodgett JR. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol Cell Biol 22: 6247-6260, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6247-6260
-
-
Scheid, M.P.1
Marignani, P.A.2
Woodgett, J.R.3
-
96
-
-
0037862006
-
Unravelling the activation mechanisms of protein kinase B/Akt
-
Scheid MP and Woodgett JR. Unravelling the activation mechanisms of protein kinase B/Akt. FEBS Lett 546: 108-112, 2003.
-
(2003)
FEBS Lett
, vol.546
, pp. 108-112
-
-
Scheid, M.P.1
Woodgett, J.R.2
-
98
-
-
16644363476
-
HIF-1 and p53: Communication of transcription factors under hypoxia
-
Schmid T, Zhou J, and Brune B. HIF-1 and p53: communication of transcription factors under hypoxia. J Cell Mol Med 8: 423-431, 2004.
-
(2004)
J Cell Mol Med
, vol.8
, pp. 423-431
-
-
Schmid, T.1
Zhou, J.2
Brune, B.3
-
100
-
-
0041440036
-
The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice
-
Scortegagna M, Morris MA, Oktay Y, Bennett M, and Garcia JA. The HIF family member EPAS1/HIF-2alpha is required for normal hematopoiesis in mice. Blood 102: 1634-1640, 2003.
-
(2003)
Blood
, vol.102
, pp. 1634-1640
-
-
Scortegagna, M.1
Morris, M.A.2
Oktay, Y.3
Bennett, M.4
Garcia, J.A.5
-
101
-
-
0037023755
-
Signaling networks that link cell proliferation and cell fate
-
Sears RC and Nevins JR. Signaling networks that link cell proliferation and cell fate. J Biol Chem 277: 11617-11620, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 11617-11620
-
-
Sears, R.C.1
Nevins, J.R.2
-
102
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza GL. Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology 19: 176-182, 2004.
-
(2004)
Physiology
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
103
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
104
-
-
0026072341
-
Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice
-
Semenza GL, Koury ST, Nejfelt MK, Gearhart JD, and Antonarakis SE. Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice. Proc Natl Acad Sci USA 88: 8725-8729, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8725-8729
-
-
Semenza, G.L.1
Koury, S.T.2
Nejfelt, M.K.3
Gearhart, J.D.4
Antonarakis, S.E.5
-
105
-
-
0026075610
-
Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene
-
Semenza GL, Nejfelt MK, Chi SM, and Antonarakis SE. Hypoxia-inducible nuclear factors bind to an enhancer element located 3′ to the human erythropoietin gene. Proc Natl Acad Sci USA 88: 5680-5684, 1991.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5680-5684
-
-
Semenza, G.L.1
Nejfelt, M.K.2
Chi, S.M.3
Antonarakis, S.E.4
-
106
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza GL and Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12: 5447-5454, 1992.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 5447-5454
-
-
Semenza, G.L.1
Wang, G.L.2
-
107
-
-
0037024550
-
Genomic and physiological analysis of oxygen sensitivity and hypoxia tolerance in PC12 cells
-
Seta K, Kim HW, Ferguson T, Kim R, Pathrose P, Yuan Y, Lu G, Spicer Z, and Millhorn DE. Genomic and physiological analysis of oxygen sensitivity and hypoxia tolerance in PC12 cells. Ann NY Acad Sci 971: 379-388, 2002.
-
(2002)
Ann NY Acad Sci
, vol.971
, pp. 379-388
-
-
Seta, K.1
Kim, H.W.2
Ferguson, T.3
Kim, R.4
Pathrose, P.5
Yuan, Y.6
Lu, G.7
Spicer, Z.8
Millhorn, D.E.9
-
108
-
-
1642443219
-
Discovery of oxygen-responsive genes in pheochromocytoma cells
-
Seta KA, Ferguson TK, and Millhorn DE. Discovery of oxygen-responsive genes in pheochromocytoma cells. Methods Enzymol 381: 449-464, 2004.
-
(2004)
Methods Enzymol
, vol.381
, pp. 449-464
-
-
Seta, K.A.1
Ferguson, T.K.2
Millhorn, D.E.3
-
109
-
-
0942265977
-
Functional genomics approach to hypoxia signaling
-
Seta KA and Millhorn DE. Functional genomics approach to hypoxia signaling. J Appl Physiol 96: 765-773, 2004.
-
(2004)
J Appl Physiol
, vol.96
, pp. 765-773
-
-
Seta, K.A.1
Millhorn, D.E.2
-
110
-
-
0037143512
-
Responding to hypoxia: Lessons from a model cell line
-
Seta KA, Spicer Z, Yuan Y, Lu G, and Millhorn DE. Responding to hypoxia: lessons from a model cell line. Sci STKE: RE11, 2002.
-
(2002)
Sci STKE
-
-
Seta, K.A.1
Spicer, Z.2
Yuan, Y.3
Lu, G.4
Millhorn, D.E.5
-
111
-
-
3342955696
-
The role of calcium in hypoxia-induced signal transduction and gene expression
-
Seta KA, Yuan Y, Spicer Z, Lu G, Bedard J, Ferguson TK, Pathrose P, Cole-Strauss A, Kaufhold A, and Millhorn DE. The role of calcium in hypoxia-induced signal transduction and gene expression. Cell Calcium 36: 331-340, 2004.
-
(2004)
Cell Calcium
, vol.36
, pp. 331-340
-
-
Seta, K.A.1
Yuan, Y.2
Spicer, Z.3
Lu, G.4
Bedard, J.5
Ferguson, T.K.6
Pathrose, P.7
Cole-Strauss, A.8
Kaufhold, A.9
Millhorn, D.E.10
-
112
-
-
2642555563
-
HIF1 and oxygen sensing in the brain
-
Sharp FR and Bernaudin M. HIF1 and oxygen sensing in the brain. Nat Rev Neurosci 5: 437-448, 2004.
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 437-448
-
-
Sharp, F.R.1
Bernaudin, M.2
-
113
-
-
0141680722
-
Repression of heme oxygenase-1 expression as a defense strategy in humans
-
Shibahara S, Nakayama M, Kitamuro T, Udono-Fujimori R, and Takahashi K. Repression of heme oxygenase-1 expression as a defense strategy in humans. Exp Biol Med (Maywood) 228: 472-473, 2003.
-
(2003)
Exp Biol Med (Maywood)
, vol.228
, pp. 472-473
-
-
Shibahara, S.1
Nakayama, M.2
Kitamuro, T.3
Udono-Fujimori, R.4
Takahashi, K.5
-
114
-
-
3242737585
-
Energetic basis of brain activity: Implications for neuroimaging
-
Shulman RG, Rothman DL, Behar KL, and Hyder F. Energetic basis of brain activity: implications for neuroimaging. Trends Neurosci 27: 489-495, 2004.
-
(2004)
Trends Neurosci
, vol.27
, pp. 489-495
-
-
Shulman, R.G.1
Rothman, D.L.2
Behar, K.L.3
Hyder, F.4
-
116
-
-
22144431886
-
Autocrine, paracrine and juxtacrine signaling by EGFR ligands
-
Singh AB and Harris RC. Autocrine, paracrine and juxtacrine signaling by EGFR ligands. Cell Signal 17: 1183-1193, 2005.
-
(2005)
Cell Signal
, vol.17
, pp. 1183-1193
-
-
Singh, A.B.1
Harris, R.C.2
-
117
-
-
0141867844
-
New roles for astrocytes: Regulation of CNS synaptogenesis
-
Slezak M and Pfrieger FW. New roles for astrocytes: regulation of CNS synaptogenesis. Trends Neurosci 26: 531-535, 2003.
-
(2003)
Trends Neurosci
, vol.26
, pp. 531-535
-
-
Slezak, M.1
Pfrieger, F.W.2
-
118
-
-
3142583358
-
Oxygen sensing in neuroendocrine cells and other cell types: Pheochromocytoma (PC12) cells as an experimental model
-
Spicer Z and Millhorn DE. Oxygen sensing in neuroendocrine cells and other cell types: pheochromocytoma (PC12) cells as an experimental model. Endocr Pathol 14: 277-291, 2003.
-
(2003)
Endocr Pathol
, vol.14
, pp. 277-291
-
-
Spicer, Z.1
Millhorn, D.E.2
-
119
-
-
0031691801
-
Oxygen tension regulates heme oxygenase-1 gene expression in mammalian cell lines
-
Takahashi S, Takahashi Y, Yoshimi T, and Miura T. Oxygen tension regulates heme oxygenase-1 gene expression in mammalian cell lines. Cell Biochem Funct 16: 183-193, 1998.
-
(1998)
Cell Biochem Funct
, vol.16
, pp. 183-193
-
-
Takahashi, S.1
Takahashi, Y.2
Yoshimi, T.3
Miura, T.4
-
120
-
-
0035108699
-
ORP150 protects against hypoxia/ischemia-induced neuronal death
-
Tamatani M, Matsuyama T, Yamaguchi A, Mitsuda N, Tsukamoto Y, Taniguchi M, Che YH, Ozawa K, Hori O, Nishimura H, Yamashita A, Okabe M, Yanagi H, Stern DM, Ogawa S, and Tohyama M. ORP150 protects against hypoxia/ischemia-induced neuronal death. Nat Med 7: 317-323, 2001.
-
(2001)
Nat Med
, vol.7
, pp. 317-323
-
-
Tamatani, M.1
Matsuyama, T.2
Yamaguchi, A.3
Mitsuda, N.4
Tsukamoto, Y.5
Taniguchi, M.6
Che, Y.H.7
Ozawa, K.8
Hori, O.9
Nishimura, H.10
Yamashita, A.11
Okabe, M.12
Yanagi, H.13
Stern, D.M.14
Ogawa, S.15
Tohyama, M.16
-
121
-
-
0032185232
-
Hypoxia-induced interleukin-6 and interleukin-8 production is mediated by platelet-activating factor and platelet-derived growth factor in primary human lung cells
-
Tamm M, Bihl M, Eickelberg O, Stulz P, Perruchoud AP, and Roth M. Hypoxia-induced interleukin-6 and interleukin-8 production is mediated by platelet-activating factor and platelet-derived growth factor in primary human lung cells. Am J Respir Cell Mol Biol 19: 653-661, 1998.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 653-661
-
-
Tamm, M.1
Bihl, M.2
Eickelberg, O.3
Stulz, P.4
Perruchoud, A.P.5
Roth, M.6
-
122
-
-
0036014523
-
Endothelial response to hypoxia: Physiologic adaptation and pathologic dysfunction
-
Ten VS and Pinsky DJ. Endothelial response to hypoxia: physiologic adaptation and pathologic dysfunction. Curr Opin Crit Care 8: 242-250, 2002.
-
(2002)
Curr Opin Crit Care
, vol.8
, pp. 242-250
-
-
Ten, V.S.1
Pinsky, D.J.2
-
123
-
-
25444432052
-
Genetic instability: The dark side of the hypoxic response
-
To KK, Koshiji M, Hammer S, and Huang LE. Genetic instability: the dark side of the hypoxic response. Cell Cycle 4: 881-882, 2005.
-
(2005)
Cell Cycle
, vol.4
, pp. 881-882
-
-
To, K.K.1
Koshiji, M.2
Hammer, S.3
Huang, L.E.4
-
124
-
-
20344394152
-
Neuroprotective role of astrocytes in cerebral ischemia: Focus on ischemic preconditioning
-
Trendelenburg G and Dirnagl U. Neuroprotective role of astrocytes in cerebral ischemia: focus on ischemic preconditioning. Glia 50: 307-320, 2005.
-
(2005)
Glia
, vol.50
, pp. 307-320
-
-
Trendelenburg, G.1
Dirnagl, U.2
-
126
-
-
23044435896
-
Astrocytes, from brain glue to communication elements: The revolution continues
-
Volterra A and Meldolesi J. Astrocytes, from brain glue to communication elements: the revolution continues. Nat Rev Neurosci 6: 626-640, 2005.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 626-640
-
-
Volterra, A.1
Meldolesi, J.2
-
127
-
-
0027427588
-
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
-
Wang GL and Semenza GL. Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem 268: 21513-21518, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 21513-21518
-
-
Wang, G.L.1
Semenza, G.L.2
-
128
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
Wang GL and Semenza GL. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 90: 4304-4308, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
129
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL and Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 270: 1230-1237, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
130
-
-
12144291605
-
Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: Potential role in neuropathogenesis
-
Wang Z, Trillo-Pazos G, Kim SY, Canki M, Morgello S, Sharer LR, Gelbard HA, Su ZZ, Kang DC, Brooks AI, Fisher PB, and Volsky DJ. Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: potential role in neuropathogenesis. J Neurovirol 10, Suppl 1: 25-32, 2004.
-
(2004)
J Neurovirol
, vol.10
, Issue.1 SUPPL.
, pp. 25-32
-
-
Wang, Z.1
Trillo-Pazos, G.2
Kim, S.Y.3
Canki, M.4
Morgello, S.5
Sharer, L.R.6
Gelbard, H.A.7
Su, Z.Z.8
Kang, D.C.9
Brooks, A.I.10
Fisher, P.B.11
Volsky, D.J.12
-
131
-
-
3342938491
-
Calcium, mitochondria and oxygen sensing in the pulmonary circulation
-
Ward JP, Snetkov VA, and Aaronson PI. Calcium, mitochondria and oxygen sensing in the pulmonary circulation. Cell Calcium 36: 209-220, 2004.
-
(2004)
Cell Calcium
, vol.36
, pp. 209-220
-
-
Ward, J.P.1
Snetkov, V.A.2
Aaronson, P.I.3
-
132
-
-
0032079558
-
Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site
-
Wenger RH, Kvietikova I, Rolfs A, Camenisch G, and Gassmann M. Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. Eur J Biochem 253: 771-777, 1998.
-
(1998)
Eur J Biochem
, vol.253
, pp. 771-777
-
-
Wenger, R.H.1
Kvietikova, I.2
Rolfs, A.3
Camenisch, G.4
Gassmann, M.5
-
134
-
-
1942541169
-
The role of epidermal growth factor and its receptors in mammalian CNS
-
Wong RW and Guillaud L. The role of epidermal growth factor and its receptors in mammalian CNS. Cytokine Growth Factor Rev 15: 147-156, 2004.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 147-156
-
-
Wong, R.W.1
Guillaud, L.2
-
135
-
-
0035195388
-
Transcriptional regulation of heme oxygenases by HIF-1α in renal medullary interstitial cells
-
Yang ZZ and Zou AP. Transcriptional regulation of heme oxygenases by HIF-1α in renal medullary interstitial cells. Am J Physiol Renal Physiol 281: F900-F908, 2001.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
-
-
Yang, Z.Z.1
Zou, A.P.2
-
136
-
-
0033068143
-
BNIP3alpha: A human homolog of mitochondrial proapoptotic protein BNIP3
-
Yasuda M, Han JW, Dionne CA, Boyd JM, and Chinnadurai G. BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3. Cancer Res 59: 533-537, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 533-537
-
-
Yasuda, M.1
Han, J.W.2
Dionne, C.A.3
Boyd, J.M.4
Chinnadurai, G.5
-
137
-
-
0141643339
-
Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha
-
Yim S, Choi SM, Choi Y, Lee N, Chung J, and Park H. Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha. J Biol Chem 278: 38260-38268, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 38260-38268
-
-
Yim, S.1
Choi, S.M.2
Choi, Y.3
Lee, N.4
Chung, J.5
Park, H.6
-
138
-
-
4644275138
-
HIF-1: The knowns and unknowns of hypoxia sensing
-
Zagorska A and Dulak J. HIF-1: the knowns and unknowns of hypoxia sensing. Acta Biochim Pol 51: 563-585, 2004.
-
(2004)
Acta Biochim Pol
, vol.51
, pp. 563-585
-
-
Zagorska, A.1
Dulak, J.2
-
139
-
-
0032169214
-
Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT
-
Zelzer E, Levy Y, Kahana C, Shilo BZ, Rubinstein M, and Cohen B. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT. EMBO J 17: 5085-5094, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 5085-5094
-
-
Zelzer, E.1
Levy, Y.2
Kahana, C.3
Shilo, B.Z.4
Rubinstein, M.5
Cohen, B.6
-
140
-
-
0141818115
-
Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-β receptor/ phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells
-
Zhang SX, Gozal D, Sachleben, LR Jr, Rane M, Klein JB, and Gozal E. Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-β receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells. FASEB J 17: 1709-1711, 2003.
-
(2003)
FASEB J
, vol.17
, pp. 1709-1711
-
-
Zhang, S.X.1
Gozal, D.2
Sachleben Jr., L.R.3
Rane, M.4
Klein, J.B.5
Gozal, E.6
-
141
-
-
0347997608
-
MAPK signal pathways in the regulation of cell proliferation in mammalian cells
-
Zhang W and Liu HT. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res 12: 9-18, 2002.
-
(2002)
Cell Res
, vol.12
, pp. 9-18
-
-
Zhang, W.1
Liu, H.T.2
-
142
-
-
0036178621
-
Detecting and responding to hypoxia
-
Zhu H, Jackson T, and Bunn HF. Detecting and responding to hypoxia. Nephrol Dial Transplant 17, Suppl 1: 3-7, 2002.
-
(2002)
Nephrol Dial Transplant
, vol.17
, Issue.1 SUPPL.
, pp. 3-7
-
-
Zhu, H.1
Jackson, T.2
Bunn, H.F.3
-
143
-
-
33244481462
-
Ser/Thr phosphorylation of IRS proteins: A molecular basis for insulin resistance
-
Zick Y. Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance. Sci STKE: PE4, 2005.
-
(2005)
Sci STKE
-
-
Zick, Y.1
|